Search Results - "activity‐based protein profiling"

A Chemoproteomic Approach to Monitor Native Iron–Sulfur Cluster Binding

Bak, Daniel W.^Aff3, Weerapana, Eranthie^Aff3

Khalimonchuk, Oleh^Aff2, Walker, John M.^Aff1

Global Assessment of Drug Target Engagement and Selectivity of Covalent Cysteine-Reactive Inhibitors Using Alkyne-Functionalized Probes

Rothweiler, Elisabeth M.^{Aff4, Aff5}, Huber, Kilian V. M.^{Aff4, Aff5}

Merk, Daniel^Aff2, Chaikuad, Apirat^Aff3, Walker, John M.^Aff1

Chemical Labeling of Protein 4′-Phosphopantetheinylation in Surfactin-Producing Nonribosomal Peptide Synthetases

Ishikawa, Fumihiro^Aff4, Tanabe, Genzoh^Aff4

Burkart, Michael^Aff2, Ishikawa, Fumihiro^Aff3, Walker, John M.^Aff1

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien, Darragh P.^aff1, Jones, Hannah B.L.^aff1, Shi, Yuqi^aff2, Guenther, Franziska^aff3, Vendrell, Iolanda^{aff1, aff4}, Viner, Rosa^aff2, Brennan, Paul E.^aff3, Mead, Emma^aff3, Zarganes-Tzitzikas, Tryfon^aff3, Davis, John B.^aff3, Pinto-Fernández, Adán^{aff1, aff4}, England, Katherine S.^aff3, Murphy, Emma J.^aff3, Turnbull, Andrew P.^aff5, Kessler, Benedikt M.^{aff1, aff4}

Production of Natural Penicillin-Binding Protein 2 and Development of a Signal-Amplified Fluorescence Polarization Assay for the Determination of 28 Beta-Lactam Antibiotics in Milk

Hu, Jia Jia, Wang, Jian Ping

Profiling of Protein Carbonylations in Ferroptosis by Chemical Proteomics

Chen, Ying^Aff4, Wang, Chu^{Aff4, Aff5}

Barcenilla, Hugo^Aff2, Diaz, David^Aff3, Walker, John M.^Aff1

Celastrol inhibits the DPYSL2-JAK/STAT pathway by targeting mito-IDHs mediated mitochondrial metabolism to exhaust breast cancer

Shi, Qiao-li^Aff1, Feng, Chen-ran^Aff1, Li, Hui-ying^{Aff2, Aff3}, Wang, Pei-li^Aff4, Chen, Peng, Wei, Xu, Kuang, Wen-hua, Li, Guan-jun, Qin, Shi-jie, Liu, Rui, Chen, Rui-xing, Zhang, Jun-zhe, Song, Ping^{Aff4, IDs41401025015480_cor1}, Yuan, Yuan^{Aff5, IDs41401025015480_cor2}, Wang, Ji-gang^{Aff1, Aff2, Aff3, Aff8, IDs41401025015480_cor3}, Huang, Ling^{Aff1, Aff2, IDs41401025015480_cor4}

Target Fishing Reveals a Novel Mechanism of N‑Acylamino Saccharin Derivatives Targeting Glyceraldehyde-3-Phosphate Dehydrogenase toward Cyanobacterial Blooms Control

Cao, Hongxuan^aff1, Huang, Zeyue^aff1, Liu, Zheng^aff1, Hameed, Muhammad Salman^aff1, Wan, Jian^aff1, Rao, Li^aff1, Makunga, Nokwanda P.^aff2, Dobrikov, Georgi M.^aff3, Su, Chen^aff4, Peng, Chao^aff4, Ren, Yanliang^aff1

Synthesis, Bioactivities, and Antibacterial Mechanism of 5‑(Thioether)‑N‑phenyl/benzyl-1,3,4-oxadiazole-2-carboxamide/amine Derivatives

Zhang, Awei, He, Hongfu, Wang, Ronghua, Shen, Zhongjie, Wu, Zengxue, Song, Runjiang, Song, Baoan

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

Koomen, David C.^Aff3, Guingab-Cagmat, Joy D.^Aff4, Oliveira, Paula S.^Aff3, Fang, Bin^Aff3, Liu, Min^Aff3, Welsh, Eric A.^Aff3, Meads, Mark B.^Aff3, Nguyen, Tuan^Aff3, Meke, Laurel^Aff4, Eschrich, Steven A.^Aff3, Shain, Kenneth H.^Aff3, Garrett, Timothy J.^Aff4, Koomen, John M.^Aff3

Bhattacharya, Sanjoy K.^Aff2, Walker, John M.^Aff1

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu

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Concentration-Dependent Enrichment Identifies Primary Protein Targets of Multitarget Bioactive Molecules

Xu, Manyi, Ma, Xingyu, Ye, Zi, Wang, Fengge, Xu, Shiqi, Zhang, Chong-Jing

Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis.

Zhang, Lydia, Tang, Michelle, Tao, Xavier, Shao, Qian, Thomas, Vienna, Shimizu, Saki, Kasano, Miki, Ishikawa, Yoshinori, Inukai, Takayuki, Nomura, Daniel

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Profiling the Activity of Deubiquitinating Enzymes Using Chemically Synthesized Ubiquitin-Based Probes

Leestemaker, Yves^{Aff4, Aff5}, de Jong, Annemieke^Aff5, Ovaa, Huib^{Aff4, Aff5}

Overkleeft, Herman S.^Aff2, Florea, Bogdan I.^Aff3, Walker, John M.^Aff1

Activity-based protein profiling and global proteome analysis reveal MASTL as a potential therapeutic target in gastric cancer

Choi, Kyoung-Min, Kim, Sung-Jin, Ji, Mi-Jung, Kim, Eunjung, Kim, Jae-Sung, Park, Hyun‑Mee, Kim, Jae-Young^{Aff1, IDs12964024017838_cor7}

Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities

Ninck, Sabrina^{Aff1, IDs40793024005772_cor1}, Klaus, Thomas, Kochetkova, Tatiana V., Esser, Sarah P., Sewald, Leonard, Kaschani, Farnusch, Bräsen, Christopher, Probst, Alexander J.^{Aff4, Aff5, Aff6}, Kublanov, Ilya V., Siebers, Bettina^{Aff2, IDs40793024005772_cor10}, Kaiser, Markus^{Aff1, IDs40793024005772_cor11}

CellEKT: A Robust Chemical Proteomics Workflow to Profile Cellular Target Engagement of Kinase Inhibitors

Rüegger, Joel ¹, Gagestein, Berend ^{1, 2}, Janssen, Antonius P.A. ¹, Valeanu, Alexandra ³, Mori, Alger Lazo ¹, van der Peet, Marielle ¹, Boutkan, Michael S. ¹, Florea, Bogdan I. ⁴, Henneman, Alex A. ², Hochstrasser, Remo ³, Wang, Haiyan ³, Westwood, Paul ³, Topp, Andreas ³, Gomez Barila, Patricia M. ⁵, Medema, Jan Paul ⁵, Jimenez, Connie R. ², Woersdoerfer, Bigna ³, Kirchner, Stephan ³, Zhang, Jitao David ³, Grether, Uwe ³, Rufer, Arne C. ³, van der Stelt, Mario ^{1, ∗}

Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics

Li, Zongmin^{aff1, aff2}, Liu, Keke^aff2, Xu, Ping^{aff1, aff2}, Yang, Jing^aff2

Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB.

King, Elizabeth, Cho, Yoojin, Hsu, Nathan, Dovala, Dustin, McKenna, Jeffrey, Tallarico, John, Schirle, Markus, Nomura, Daniel

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Antibiotic target discovery by integrated phenotypic and activity-based profiling of electrophilic fragments

Jin, Yizhen ^{1, 2, 3}, Jana, Sadhan ^{2, 3}, Abbasov, Mikail E. ^{2, ∗}, Lin, Hening ^{4, 5, 6, ∗∗}