Sökresultat - "Selective vulnerability"

Molecular signatures of regional vulnerability to tauopathy in excitatory cortical neurons

Broekaart, Diede W. M.^{Aff1, Aff2}, Sharma, Abhijeet^{Aff1, Aff2}, Ramakrishnan, Aarthi, Chongtham, Anjalika^{Aff1, Aff2}, Günther, Dorothee M.^{Aff1, Aff2}, Subramaniyan, Saraswathi^{Aff1, Aff2}, Wang, Minghui^{Aff4, Aff5}, Patel, Vishwendra, Zhang, Bin^{Aff4, Aff5}, Grinberg, Lea T., Blitzer, Robert D.^{Aff7, Aff8}, Schmidt, Eric F., Shen, Li, Hof, Patrick R.^{Aff2, Aff3}, Pereira, Ana C.^{Aff1, Aff2, IDs00401025028792_cor1}

Locus coeruleus integrity and neuropsychiatric symptoms in a cohort of early‐ and late‐onset Alzheimer's disease

Falgàs, Neus, Peña‐González, Marta, Val‐Guardiola, Andrea, Pérez‐Millan, Agnès, Guillén, Núria, Sarto, Jordi, Esteller, Diana, Bosch, Beatriz, Fernández‐Villullas, Guadalupe, Tort‐Merino, Adrià, Mayà, Gerard, Augé, Josep Maria, Iranzo, Alex, Balasa, Mircea, Lladó, Albert, Morales‐Ruiz, Manuel, Bargalló, Núria, Muñoz‐Moreno, Emma, Grinberg, Lea T, Sánchez‐Valle, Raquel

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Comorbid neuropathology and atypical presentation of Alzheimer's disease

Pina‐Escudero, Stefanie D, La Joie, Renaud, Spina, Salvatore, Hwang, Ji‐Hye, Miller, Zachary A, Huang, Eric J, Grant, Harli, Mundada, Nidhi S, Boxer, Adam L, Gorno‐Tempini, Maria Luisa, Rosen, Howard J, Kramer, Joel H, Miller, Bruce L, Seeley, William W, Rabinovici, Gil D, Grinberg, Lea Tenenholz

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hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

Ian Weidling, Christina N. Preiss, Sarah E. Chancellor, Gyan Srivastava, Lauren Gibilisco, Gen Lin, Melanie Shackett Brennan, Janice Lee, Lindsay M. Roth, Olga Morozova, Kyong Nyon Nam, Nehal R. Patel, Qing Liu, J. K. Thomas, Peter Reinhardt, Ruven Wilkens, Dagmar E. Ehrnhoefer, Andreas Striebinger, Stefan Barghorn, Christina Xanthopoulos, Marie-Theres Weil, Sandra Biesinger, Miroslav Cik, Nandini Romanul, Kiran Yanamandra, Alessandra M. Welker, Jessica Wu, Laura Gasparini, Jan Stöhr, Xavier Langlois, Justine D. Manos

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TRPA1 exacerbates selective retinal ganglion cell vulnerability under acute ocular hypertension

Wenhan Lu, Yu Wang, Wei Hu, Xinyi Lin, Xiaoyu Tong, Yi Tian, Yuning Chen, Yicong Wang, Yan Xiao, Hongfang Yang, Yi Feng, Xinghuai Sun

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Selective cellular and regional vulnerability in frontotemporal lobar degeneration: a scoping review

Kashif Ravasia, Veronica Hirsch-Reinshagen

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Alzheimer's disease phenotypes show different sleep architecture

Falgàs, Neus, Walsh, Christine M, Yack, Leslie, Simon, Alexander J, Allen, Isabel E, Kramer, Joel H, Rosen, Howard J, La Joie, Renaud, Rabinovici, Gil, Miller, Bruce, Spina, Salvatore, Seeley, William W, Ranasinghe, Kamalini, Vossel, Keith, Neylan, Thomas C, Grinberg, Lea T

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Down syndrome frontal cortex layer III and layer V pyramidal neurons exhibit lamina specific degeneration in aged individuals

Alldred, Melissa J.^{Aff1, Aff2}, Ibrahim, Kyrillos W., Pidikiti, Harshitha, Chiosis, Gabriela^{Aff5, Aff6}, Mufson, Elliott J., Stutzmann, Grace E., Ginsberg, Stephen D.^{Aff1, Aff2, Aff3, Aff4, IDs4047802401891z_cor7}

Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome

Alldred, Melissa J.^{Aff1, Aff2}, Pidikiti, Harshitha, Ibrahim, Kyrillos W., Lee, Sang Han^{Aff1, Aff2}, Heguy, Adriana^{Aff3, Aff4}, Hoffman, Gabriel E.^{Aff5, Aff6}, Roussos, Panos^{Aff5, Aff6}, Wisniewski, Thomas^{Aff2, Aff4, Aff7, Aff9}, Wegiel, Jerzy, Stutzmann, Grace E., Mufson, Elliott J., Ginsberg, Stephen D.^{Aff1, Aff2, Aff8, Aff9, IDs00401024027680_cor12}

Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice

Wang, Nan ^{1, 2, 7}, Zhang, Shasha ^{1, 2, 7}, Langfelder, Peter ^{1, 2, 7}, Ramanathan, Lalini ^{1, 2}, Gao, Fuying ^{1, 2}, Plascencia, Mary ^{1, 2}, Vaca, Raymond ^{1, 2}, Gu, Xiaofeng ^{1, 2}, Deng, Linna ^{1, 2}, Dionisio, Leonardo E. ^{1, 2}, Vu, Ha ³, Maciejewski, Emily ³, Ernst, Jason ³, Prasad, Brinda C. ⁴, Vogt, Thomas F. ⁴, Horvath, Steve ^{5, 6}, Aaronson, Jeffrey S. ⁴, Rosinski, Jim ⁴, Yang, X. William ^{1, 2, 8, ∗}

A novel three-dimensional method for detailed analysis of RGC central projections under acute ocular hypertension

Lu, Wenhan ^{a, c, d}, Wang, Yu ^{d, e}, Hu, Wei ^{d, e}, Lin, Xinyi ^f, Tong, Xiaoyu ^{d, e}, Tian, Yi ^{a, c}, Chen, Yuning ^g, Wang, Yicong ^{d, e}, Xiao, Yan ^{d, e}, Yang, Hongfang ^{a, c, ⁎}, Feng, Yi ^{d, e, ⁎⁎}, Sun, Xinghuai ^{a, b, c, ⁎⁎⁎}

Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging

Sohee Jeon, Miranda A. Salvo, Alia O. Alia, Jelena Popovic, Mitchell Zagardo, Sidhanth Chandra, Malik Nassan, David Gate, Robert Vassar, Leah K. Cuddy

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A review of proposed mechanisms for neurodegenerative disease

Benjamin M. Kelser, Eric M. Teichner, Robert C. Subtirelu, Kevin N. Hoss

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Selective Inhibitory Circuit Dysfunction after Chronic Frontal Lobe Contusion.

Nolan, Amber L, Sohal, Vikaas S, Rosi, Susanna

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Histopathological Assessments of Animal Models of Cerebral Ischemia

Raval, Ami P.^Aff1, Hu, Bingren^Aff2

Chen, Jun^AffID1, Xu, Xiao-Ming^AffID2, Xu, Zao C.^AffID3, Zhang, John H.^AffID4

Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease.

Steinkellner, Thomas, Conrad, William S, Kovacs, Imre, Rissman, Robert A, Lee, Edward B, Trojanowski, John Q, Freyberg, Zachary, Roy, Subhojit, Luk, Kelvin C, Lee, Virginia M, Hnasko, Thomas S

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Cerebellar Heterogeneity and Selective vulnerability in Spinocerebellar Ataxia Type 1 (SCA1)

Katherine Hamel, Emmanuel Labrada Moncada, Carrie Sheeler, Juao-Guilherme Rosa, Stephen Gilliat, Ying Zhang, Marija Cvetanovic

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Comorbid neuropathology and atypical presentation of Alzheimer's disease

Stefanie D. Pina‐Escudero, Renaud La Joie, Salvatore Spina, Ji‐Hye Hwang, Zachary A. Miller, Eric J. Huang, Harli Grant, Nidhi S. Mundada, Adam L. Boxer, Maria Luisa Gorno‐Tempini, Howard J. Rosen, Joel H. Kramer, Bruce L. Miller, William W. Seeley, Gil D. Rabinovici, Lea Tenenholz Grinberg

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Deepen into sleep and wake patterns across Alzheimer's disease phenotypes

Falgàs, Neus, Walsh, Christine M, Neylan, Thomas C, Grinberg, Lea T

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The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease

Matchett, Billie J, Grinberg, Lea T, Theofilas, Panos, Murray, Melissa E

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