Sökresultat - "AMINOPEPTIDASES"

Inhibition of methionine aminopeptidase in C2C12 myoblasts disrupts cell integrity via increasing endoplasmic reticulum stress.

Osana S; Department of Sports and Medical Science, Graduate School of Emergency Medical System, Kokushikan University, Tokyo 206-8515, Japan; Center for Neuroscience and Biomedical Engineering, University of Electro-Communications, Tokyo 182-8585, Japan. Electronic address: shiono@kokushikan.ac.jp., Tsai CT; The Institute of Physical Education, Kokushikan University, Tokyo 206-8515, Japan., Suzuki N; Department of Rehabilitation Medicine, Graduate School of Medicine, Tohoku University, Miyagi 980-8575, Japan., Murayama K; Division of Biomedical Measurements and Diagnostics, Graduate School of Biomedical Engineering, Tohoku University, Miyagi 980-8575, Japan., Kaneko M; The Institute of Physical Education, Kokushikan University, Tokyo 206-8515, Japan., Hata K; Department of Sports and Medical Science, Graduate School of Emergency Medical System, Kokushikan University, Tokyo 206-8515, Japan., Takada H; Designing Future Health Initiative, Center for Promotion of Innovation Strategy, Head Office of Enterprise Partnerships, Tohoku University, Miyagi 980-8579, Japan., Kano Y; Center for Neuroscience and Biomedical Engineering, University of Electro-Communications, Tokyo 182-8585, Japan; Department of Engineering Science, Graduate School of Informatics and Engineering, University of Electro-Communications, Tokyo 182-8585, Japan., Nagatomi R; Designing Future Health Initiative, Center for Promotion of Innovation Strategy, Head Office of Enterprise Partnerships, Tohoku University, Miyagi 980-8579, Japan. Electronic address: ryoichi.nagatomi.c4@tohoku.ac.jp.

Journal Article , 2025

Methionine Aminopeptidase 2 (MetAP2) Inhibitor BL6 Attenuates Inflammation in Cultured Microglia and in a Mouse Model of Alzheimer's Disease.

Zhang X; Division of Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA., Subbanna S; Division of Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA., Williams CRO; Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA., Canals-Baker S; Division of Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA., Hashim A; Division of Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA., Wilson DA; Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.; Department of Child and Adolescent Psychiatry, New York University Medical Center, New York, NY 10016, USA., Weiss LM; Department of Pathology/Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Shukla S; School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14201, USA., Chokkalingam P; School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14201, USA., Das S; School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14201, USA., Das BC; School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14201, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Saito M; Division of Neurochemistry, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.; Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA.

Journal Article , 2025

Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity.

Cornelius P; SynDevRx, Inc., Cambridge, Massachusetts., Mayes BA; SynDevRx, Inc., Cambridge, Massachusetts., Petersen JS; SynDevRx, Inc., Cambridge, Massachusetts., Turnquist DJ; SynDevRx, Inc., Cambridge, Massachusetts., Dufour PJ; SynDevRx, Inc., Cambridge, Massachusetts., Dannenberg AJ; Emerald BioVentures, New York, New York., Shanahan JM; SynDevRx, Inc., Cambridge, Massachusetts., Carver BJ; SynDevRx, Inc., Cambridge, Massachusetts.

Journal Article; Research Support, Non-U.S. Gov't , 2024

ERAP1 Activity Modulates the Immunopeptidome but Also Affects the Proteome, Metabolism, and Stress Responses in Cancer Cells.

Nikopaschou M; National Centre for Scientific Research Demokritos, Agia Paraskevi, Greece; Department of Chemistry, National and Kapodistrian University of Athens, Zografou, Greece., Samiotaki M; Biomedical Sciences Research Center 'Alexander Fleming', Institute for Bioinnovation, Vari, Greece., Stylianaki EA; Biomedical Sciences Research Center 'Alexander Fleming', Institute for Fundamental Biomedical Research, Vari, Greece., Król K; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Gragera P; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Raja A; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Aidinis V; Biomedical Sciences Research Center 'Alexander Fleming', Institute for Fundamental Biomedical Research, Vari, Greece., Chroni A; National Centre for Scientific Research Demokritos, Agia Paraskevi, Greece., Fruci D; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Panayotou G; Biomedical Sciences Research Center 'Alexander Fleming', Institute for Bioinnovation, Vari, Greece., Stratikos E; National Centre for Scientific Research Demokritos, Agia Paraskevi, Greece; Department of Chemistry, National and Kapodistrian University of Athens, Zografou, Greece. Electronic address: estratikos@chem.uoa.gr.

Journal Article , 2025

Simultaneously Enhancing the Catalytic Activity and Thermostability of Pseudomonas aeruginosa Aminopeptidase via Structure-based Design.

Liu WL; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China., Wen ZH; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China., Li QY; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China.; Key Laboratory of Guangxi Biorefinery, Nanning 530003, PR China., Liu HB; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China., Li QL; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China., Chen HY; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China., Tang AX; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China.; Key Laboratory of Guangxi Biorefinery, Nanning 530003, PR China., Liu YY; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, PR China.; Key Laboratory of Guangxi Biorefinery, Nanning 530003, PR China.

Journal Article , 2025

A Halophilic Aminopeptidase With Broad Substrate Specificity: Exploring Its Catalytic Potential and Application in Salt-Fermented Foods.

Hou J; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Mao YL; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Lu YH; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Nwankwo C; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Hu Y; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Zhu LR; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Dong XY; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China., Cui HL; School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China.

Journal Article , 2025

Defining a genetic background for bamboo spine and axial spondyloarthritis.

Özkaya ŞÇ; Marmara University, Institute of Health Sciences, Department of Medical Biology and Genetics, Istanbul, Turkey., Abacar K; Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey., Dilek YE; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem University, Istanbul, Turkey., Akçapınar GB; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem University, Istanbul, Turkey., Atagündüz MP; Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey., Erzik C; Marmara University, Institute of Health Sciences, Department of Medical Biology and Genetics, Istanbul, Turkey; Department of Medical Biology, School of Medicine, Marmara University, Istanbul, Turkey. Electronic address: canerzik@marmara.edu.tr.

Journal Article , 2025

PaAP-Activatable NIR Probe for Diagnosing, Imaging, and Discovering Small-Molecule Therapeutics against Implant-Associated Biofilm Infections.

Liu K; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Liu Y; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Wang Q; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Nazaré M; Medicinal Chemistry, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, 13125 Berlin, Germany., Zhang L; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Pan X; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Hu HY; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

Journal Article , 2025

Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.

Lee Y; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Kim H; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.; Division of Medical Sciences, College of Medicine, Yonsei University, Seoul, 03722, Republic of Korea., Lee E; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Hahn H; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Heo Y; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Jang DM; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea., Kwak K; Division of Medical Sciences, College of Medicine, Yonsei University, Seoul, 03722, Republic of Korea., Kim HJ; College of Pharmacy, Woosuk University, Wanju, 55338, Republic of Korea. hyojungkim@woosuk.ac.kr., Kim HS; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea. hskim@ncc.re.kr.

Journal Article , 2023

A novel directed enzymolysis strategy for the preparation of umami peptides in Stropharia rugosoannulata and its mechanism of taste perception.

Chen D; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China., Rong M; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China., Tang S; School of Food Science and Technology, Shihezi University, Shihezi 832000, China., Zhang C; Department of Micro/Nano Electronics, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China., Wei H; Department of Micro/Nano Electronics, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China., Yuan Z; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China., Miao T; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China., Song H; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China., Jiang H; School of Life Science and Technology, Inner Mongolia University of Science and Technology, Baotou 014010, China., Yang Y; Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Engineering Research Center of Edible Fungi, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, the People's Republic of China, 1000 Jinqi Road, Shanghai 201403, China. Electronic address: yangyan@saas.sh.cn., Zhang L; Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China. Electronic address: ljzhang@chem.ecnu.edu.cn.

Journal Article , 2025

The expression of ERAP1 is favorable for the prognosis and immunotherapy in colorectal cancer: a study based on the bioinformatic and immunohistochemical analysis.

Gan L; Department of Gastroenterological Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China., Yang C; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China., Zhao L; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China., Wang S; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China., Ye Y; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China., Gao Z; Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China. gaozhidong@pkuph.edu.cn.

Journal Article , 2025

Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population.

Kril I; Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wrocław, Poland., Wiśniewski A; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wrocław, Poland., Tarnowska A; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wrocław, Poland., Lishchuk-Yakymovych K; Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine., Bojko Y; Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine., Kuśnierczyk P; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wrocław, Poland., Chopyak VV; Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine., Nowak I; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wrocław, Poland.

Journal Article , 2025

Genetic and enzymatic profiling reveals aminopeptidase potential of Lactobacillus acidophilus ItalPN270.

Barreto Pinilla CM; Dairy Technology Center (TECNOLAT) of the Food Technology Institute (ITAL), 13070-178 Campinas, São Paulo, Brazil., Guzman Escudero F; Medical School, Universidad Cientifica del Sur, 150142 Lima, Peru., Maria Spadoti L; Dairy Technology Center (TECNOLAT) of the Food Technology Institute (ITAL), 13070-178 Campinas, São Paulo, Brazil., Brandelli A; Laboratory of Applied Microbiology and Biochemistry, Institute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), 91501-970 Porto Alegre, Brazil., Torres Silva E Alves A; Dairy Technology Center (TECNOLAT) of the Food Technology Institute (ITAL), 13070-178 Campinas, São Paulo, Brazil.

Journal Article , 2025

Extracellular aminopeptidase regulates exopolysaccharide production of Pseudomonas aeruginosa via quorum sensing.

Zhao T; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, No. 1 Yanqihu East Rd, Huairou District, Beijing 101408, PR China., Lei F; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; School of Life Sciences, Yunnan University, Kunming 650091, China., Zhang Z; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, No. 1 Yanqihu East Rd, Huairou District, Beijing 101408, PR China., Wang D; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China., Ma LZ; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Medical School, University of Chinese Academy of Sciences, No. 1 Yanqihu East Rd, Huairou District, Beijing 101408, PR China.; College of Life Sciences, University of Chinese Academy of Sciences, No. 1 Yanqihu East Rd, Huairou District, Beijing 101408, PR China.

Journal Article , 2025

Mendelian randomization analysis identifies ERAP1 and IL23R as potential drug targets for ankylosing spondylitis.

Wu W; Department of Transfusion Medicine, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China., Sun K; Department of Transfusion Medicine, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China., Zhang C; School of Medical Laboratory, Shandong Second Medical University, Weifang, Shandong, China., Zhang Q; Department of Orthopedics, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China. Electronic address: huanxj@sdmc.edu.cn., Huang X; Department of Transfusion Medicine, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China. Electronic address: zcjy@stu.sdsmu.edu.cn.

Journal Article , 2025

The association of HLA-DRB1 allele group but not HLA-B or ERAP1-rs7063 gene polymorphisms with atopic dermatitis.

Niepiekło-Miniewska W; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland., Matusiak Ł; Department of Dermato-Venereology, 4th Military Hospital, Wroclaw, Poland; Faculty of Medicine, Wroclaw University of Science and Technology, Wroclaw, Poland., Narbutt J; Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Poland., Lesiak A; Laboratory of Autoinflammatory, Genetic and Rare Skin Disorders, Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Poland; Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Poland., Kuna P; Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland., Szepietowski JC; Department of Dermato-Venereology, 4th Military Hospital, Wroclaw, Poland; Faculty of Medicine, Wroclaw University of Science and Technology, Wroclaw, Poland., Kuśnierczyk P; Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.

Journal Article , 2025

Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis.

Rayinda T; St John's Institute of Dermatology, King's College London, London, United Kingdom.; Department of Dermatology and Venereology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia., Dand N; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., McSweeney SM; St John's Institute of Dermatology, King's College London, London, United Kingdom., Christou E; St John's Institute of Dermatology, King's College London, London, United Kingdom., Ung CY; St John's Institute of Dermatology, King's College London, London, United Kingdom., Stefanato CM; St John's Institute of Dermatology, King's College London, London, United Kingdom., Fenton DA; St John's Institute of Dermatology, King's College London, London, United Kingdom., Harries M; Centre for Dermatology Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.; Department of Dermatology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom., Palamaras I; Department of Dermatology, Barnet and Chase Farm Hospitals, Royal Free NHS Foundation Trust, London, United Kingdom., Tidman A; Department of Dermatology, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Holmes S; Department of Dermatology, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Koutalopoulou A; Department of Dermatology, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom., Ardern-Jones M; Department of Dermatology, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom., Kaur M; Department of Dermatology, Solihull Hospital, Solihull, United Kingdom., Papanikou S; Department of Dermatology and Venereology of NHS, Hospital of Skin and Venereal Diseases, Andreas Syggros, Athens, Greece., Chasapi V; Department of Dermatology and Venereology of NHS, Hospital of Skin and Venereal Diseases, Andreas Syggros, Athens, Greece., Vañó-Galvan S; Hair Disorders Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, Spain., Saceda-Corralo D; Hair Disorders Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, Spain., Melián-Olivera A; Hair Disorders Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, Spain., Azcarraga-Llobet C; Hair Disorders Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, Spain., Lobato-Berezo A; Servicio de Dermatología Hospital del Mar-Parc de Salut Mar, Barcelona, Spain., Bustamante M; Institute for Global Health (ISGlobal), Barcelona, Spain., Sunyer J; Institute for Global Health (ISGlobal), Barcelona, Spain., Starace MVR; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Piraccini BM; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Wiss IP; Harvard Medical School and Lahey Hospital and Medical Center, Boston, Massachusetts., Senna MM; Harvard Medical School and Lahey Hospital and Medical Center, Boston, Massachusetts., Singh R; Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Hillmann K; Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Kanti-Schmidt V; Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Johannes Wesling Klinikum Minden, Department of Dermatology, Venerology, Allergology and Phlebology, University Hospital of the Ruhr University of Bochum, Minden, Germany., Blume-Peytavi U; Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany., McGrath JA; St John's Institute of Dermatology, King's College London, London, United Kingdom., Simpson MA; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Tziotzios C; Hair Disorders Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, Spain.

Journal Article; Meta-Analysis; Comment , 2025

The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis.

Su SH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China., Cai XQ; Department of Respiratory and Critical Care Medicine, Anhui Chest Hospital, Hefei, China., Li YH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China., Xu AH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China., Huang Q; School of Public Health, Anhui Medical University, Hefei, China. huangxiaoxi201602@163.com., Niu H; Department of Respiratory and Critical Care Medicine, Anhui Chest Hospital, Hefei, China. nhvssj@sina.com., You QH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China. amormor@126.com., Sun GY; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei, China. sungengy@126.com.

Journal Article , 2025

Genetic analysis implicates ERAP1 and HLA as risk factors for severe Puumala virus infection.

Haapaniemi H; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland., Strausz S; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland.; Department of Oral and Maxillofacial Diseases, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 1, 00290 Helsinki, Finland.; Department of Plastic Surgery, Cleft Palate and Craniofacial Center, Helsinki University Hospital and University of Helsinki, Stenbäckinkatu 11, 00290 Helsinki, Finland.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, United States., Tervi A; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland., Jones SE; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland., Kanerva M; Department of Hospital Hygiene and Infection Control, TYKS Turku University Hospital, Kiinamyllynkatu 4-8, 20521 Turku, Finland., Abner E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia tn 23b, 51010 Tartu, Estonia., Fors Connolly AM; Department of Clinical Microbiology, Umeå University, Biologihuset, 90187 Umeå, Sweden., Ollila HM; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, United States.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRB 444 Boston, MA, United States.; Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, United States.

FinnGen, Estonian Biobank Research Team

Journal Article , 2025

Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patients.

Soangra R; Crean College of Health and Behavioral Sciences, Chapman University, Orange, CA, 92866, USA.; Fowler School of Engineering, Chapman University, Orange, CA, 92866, USA., Grant-Beuttler M; Department of Physical Therapy, Oregon Institute of Technology, Klamath Falls, OR, 97601, USA., Chang H; Division of Metabolic Disorders, CHOC Children's Hospital, Orange, CA, 92868, USA., Wang RY; Division of Metabolic Disorders, CHOC Children's Hospital, Orange, CA, 92868, USA. RaWang@choc.org.; Department of Pediatrics, University of California-Irvine School of Medicine, Orange, CA, 92868, USA. RaWang@choc.org.

Journal Article; Research Support, N.I.H., Extramural , 2025