Search Results - "AP-1"

The Activation of the CCND1 Promoter by AP-1 and SOX Transcription Factors in PC3 Prostate Cancer Cells Can Be Prevented by Anacardic Acid Analogs.

Brunie M; Biology Department, Université de Moncton, Moncton, NB, Canada., Robichaud MA; Chemistry and Biochemistry Department, Université de Moncton, Moncton, NB, Canada., Touaibia M; Chemistry and Biochemistry Department, Université de Moncton, Moncton, NB, Canada., Martin LJ; Biology Department, Université de Moncton, Moncton, NB, Canada. Luc.Martin@umoncton.ca.

Journal Article , 2025

Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer.

Dayanc B; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Eris S; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Gulfirat NE; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Ozden-Yilmaz G; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Cakiroglu E; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Coskun Deniz OS; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Karakülah G; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Erkek-Ozhan S; Izmir Biomedicine and Genome Center, Izmir, Türkiye.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye., Senturk S; Izmir Biomedicine and Genome Center, Izmir, Türkiye. serif.senturk@ibg.edu.tr.; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Türkiye. serif.senturk@ibg.edu.tr.

Journal Article , 2025

AP1-mediated reprogramming of EGFR expression triggers resistance to BLU-667 and LOXO-292 in RET-rearranged tumors.

Esposito D; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Ascione CM; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Belli S; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Napolitano F; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Servetto A; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Pepe F; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy., Malapelle U; Department of Public Health, University of Naples Federico II, Naples, Italy., Iaccarino A; Department of Public Health, University of Naples Federico II, Naples, Italy., Troncone G; Department of Public Health, University of Naples Federico II, Naples, Italy., Barone D; University Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy.; Isola Tiberina Hospital, Gemelli Isola, Rome, Italy., Bria E; University Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy.; Isola Tiberina Hospital, Gemelli Isola, Rome, Italy., Ferrara R; University Vita-Salute San Raffaele, Milan, Italy., Lorenzini D; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Lombardia, Italy., Lo Russo G; Medical Oncology Department 1, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy., Ghigna MR; Department of Pathology, Gustave Roussy, Villejuif, France., Marinello A; Department of Cancer Medicine, Gustave Roussy, Villejuif, France., Aldea M; Department of Cancer Medicine, Gustave Roussy, Villejuif, France.; Paris-Saclay University, Paris, France., Besse B; Department of Cancer Medicine, Gustave Roussy, Villejuif, France.; Paris-Saclay University, Paris, France., Formisano L; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy. luigi.formisano1@unina.it., Bianco R; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, 80131, Italy. robianco@unina.it.

Journal Article , 2025

Upregulated CEMIP promotes intervertebral disc degeneration via AP-1-mediated change in chromatin accessibility.

Shu S; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Zhang X; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Feng Z; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Liu Z; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Wang K; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Li F; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Wu Y; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Shi B; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Qiu Y; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Zhu Z; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Bao H; Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Journal Article , 2025

Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation.

Cadefau-Fabregat M; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain.; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Doctoral Program in Biomedicine, Universitat de Barcelona (UB), Barcelona, Spain., Martínez-Cebrián G; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Lorenzi L; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Weiss FD; Institute of Innate Immunity, Department for Systems Immunology and Proteomics, Medical Faculty, University Hospital Bonn, University of Bonn, 53127, Bonn, Germany., Frank AK; The Finsen Laboratory, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre (BRIC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Castelló-García JM; Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Julià-Vilella E; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain.; Doctoral Program in Biomedicine, Universitat de Barcelona (UB), Barcelona, Spain., Gámez-García A; Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Yera L; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., de Castro CPM; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain.; Doctoral Program in Biomedicine, Universitat de Barcelona (UB), Barcelona, Spain., Wang YF; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK., Meissner F; Institute of Innate Immunity, Department for Systems Immunology and Proteomics, Medical Faculty, University Hospital Bonn, University of Bonn, 53127, Bonn, Germany., Vaquero A; Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Merkenschlager M; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK., Porse BT; The Finsen Laboratory, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre (BRIC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Cuartero S; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain. scuartero@carrerasresearch.org.; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain. scuartero@carrerasresearch.org.

Journal Article , 2025

Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos.

Hartley A; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH, UK.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Galbraith LCA; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Shaw R; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Tibbo A; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH, UK.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Veeratterapillay R; Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK., Wilson L; Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK., Heer R; Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK., Blyth K; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH, UK.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Leung H; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH, UK.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK., Ahmad I; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH, UK. Imran.Ahmad@glasgow.ac.uk.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK. Imran.Ahmad@glasgow.ac.uk.

Journal Article , 2025

RAGE/AP-1/OTR signaling pathway in rat hippocampus DG involved in CUS induced depressive-like behaviors.

Li X; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China., Wang X; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China., Xue L; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China., Luo L; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China., Hu L; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China., Jiang W; Key Laboratory of Molecular and Biochemical Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, China. Electronic address: jiangwengao@cqmu.edu.cn.

Journal Article , 2025

Anti-inflammatory effects of Lactiplantibacillus plantarum strains through MAPK, NF-κB, and AP-1 signaling pathways and its application in soy milk.

Lee YR; Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea., Lee HW; Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea., Park KM; Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea., Lee NK; Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea., Paik HD; Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea. Electronic address: hdpaik@konkuk.ac.kr.

Journal Article , 2025

Serum Starvation-induced ROS Production Activates the ERK-AP-1-TfR1 Pathway to Up-regulate Survivin to Support Nasopharyngeal Carcinoma Cell Viability.

Wang CC; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C.; Department of Otolaryngology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C., Hwang TZ; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C.; Department of Otolaryngology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C., Lien CF; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C.; Department of Otolaryngology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C., Li Y; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C., Lan YY; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C.; yyinmed@isu.edu.tw.

Journal Article , 2025

Single-cell RNA sequencing indicates AP-1 as a potential therapeutic target for autoimmune uveitis.

Zhao S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou 510060, China., Wu D; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou 510060, China., Lu Y; National Clinical Research Center for Eye Diseases, Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Zhu L; Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China., Wang S; Sun Yat-sen University, Guangzhou 510060, China., Li Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou 510060, China., Peng X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou 510060, China., Li H; Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China., Xu X; Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China. Electronic address: xuxu0139@hotmail.com., Su W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou 510060, China. Electronic address: suwenru@sjtu.edu.cn.

Journal Article , 2025

K Ca 3.1 upregulation mediated by Ang II-induced JNK/AP-1 activation contributes to atrial fibrosis.

Zhang D; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China., Li G; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China., Liu X; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China., Wang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an 710061, Shaanxi, China., Wu J; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China., Ren Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an 710061, Shaanxi, China., She G; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an 710061, Shaanxi, China., Zheng D; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China., Zhao Y; Central Laboratory, Shanghai Xuhui Central Hospital, 366 North Longchuan Road, Shanghai 200031, China., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an 710061, Shaanxi, China., Li M; Institute of Biology and Medical Sciences, Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China. Electronic address: minl_zju@126.com., Zhao L; Department of Pathology and Pathophysiology, Suzhou Medical College of Soochow University, 199 Ren-ai Road, Suzhou 215123, Jiangsu, China; MOE Key Laboratory of Geriatric Diseases and Immunology, School of Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, Jiangsu, China. Electronic address: lmzhao@suda.edu.cn.

Journal Article , 2025

DUBR non-coding RNA regulates gene expression by affecting AP-1 enhancer accessibility.

Hall SD; Department of Chemistry and Biochemistry, University of California San Diego, Urey Hall Room 6213, 9500 Gilman Drive MC 0314, La Jolla, CA, 92093, USA., Tran K; Department of Chemistry and Biochemistry, University of California San Diego, Urey Hall Room 6213, 9500 Gilman Drive MC 0314, La Jolla, CA, 92093, USA., Zhu J; Department of Chemistry and Biochemistry, University of California San Diego, Urey Hall Room 6213, 9500 Gilman Drive MC 0314, La Jolla, CA, 92093, USA., Su T; Department of Chemistry and Biochemistry, University of California San Diego, Urey Hall Room 6213, 9500 Gilman Drive MC 0314, La Jolla, CA, 92093, USA., McHugh CA; Department of Chemistry and Biochemistry, University of California San Diego, Urey Hall Room 6213, 9500 Gilman Drive MC 0314, La Jolla, CA, 92093, USA. c1mchugh@ucsd.edu.

Journal Article , 2025

Maternal Melatonin Contributes to Offspring Hair Follicle Development Through Transcriptional Regulation of the AP-1 Complex and MAPK Pathway.

Feng Y; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Yang R; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Zhang J; College of Animal Science and Technology, Shihezi University, Shihezi 832003, China., Yuan H; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Yan Z; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Wang P; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Ma X; Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China., Liu T; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China., Gun S; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.

Journal Article , 2025

FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1.

Ferreira FJ; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal.; Vertebrate Development and Regeneration Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.; Aging and Aneuploidy Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.; Graduate Program in Areas of Basic and Applied Biology (GABBA), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, 4050-313, Porto, Portugal., Galhardo M; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal.; Vertebrate Development and Regeneration Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.; Aging and Aneuploidy Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal., Nogueira JM; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal.; Vertebrate Development and Regeneration Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.; Doctoral program in Molecular and Cell Biology (MCbiology), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, 4050-313, Porto, Portugal., Teixeira J; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal.; Vertebrate Development and Regeneration Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.; Doctoral program in Molecular and Cell Biology (MCbiology), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, 4050-313, Porto, Portugal., Logarinho E; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal. elsa.logarinho@i3s.up.pt.; Aging and Aneuploidy Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal. elsa.logarinho@i3s.up.pt., Bessa J; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Portugal. jose.bessa@ibmc.up.pt.; Vertebrate Development and Regeneration Group, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal. jose.bessa@ibmc.up.pt.

Journal Article , 2025

Celecoxib paradoxically induces COX-2 expression and astrocyte activation through the ERK/JNK/AP-1 signaling pathway in the cerebral cortex of rats.

Wei KC; Department of Dermatology, Kaohsiung Veterans General Hospital, Kaoshiung, 813, Taiwan; College of Medicine, National Yang-Ming Chiao Tung University, Taipei, 112, Taiwan., Lin JT; Master and PhD Programs in Pharmacology and Toxicology, School of Medicine, Tzu Chi University, Hualien, 970, Taiwan., Lin CH; Master and PhD Programs in Pharmacology and Toxicology, School of Medicine, Tzu Chi University, Hualien, 970, Taiwan; Department of Pharmacology, School of Medicine, Tzu Chi University, Hualien, 970, Taiwan. Electronic address: chlin97@mail.tcu.edu.tw.

Journal Article , 2025

Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling.

Jiao YX; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China., Zhou YM; School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China., Zhou ZW; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China., He Y; Shenzhen University General Hospital, Shenzhen University, Shenzhen 518055, China., Liu S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China., Xu XT; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China., Ji K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China; School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China. Electronic address: jkm@szu.edu.cn., Chen JJ; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China. Electronic address: chenjj@szu.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Curcumin relieves CFA-induced inflammatory pain by inhibiting the AP-1/c-Jun-CCL2-CCR2 pathway in the spinal dorsal horn.

Zhu Y; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Jiang Y; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Lu X; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Li S; Kangda College of Nanjing Medical University Department, Lianyungang, Jiangsu, China., Liu F; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Xu Y; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Tian Y; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Gao L; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China., Wei L; Department of Anesthesiology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.

Journal Article , 2025

Lnc NBAT1 Inhibits the Proliferation and Migration of Liver Cancer Cells Through the miR-21/PDCD4/AP-1 Signaling Axis.

Zai H; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Wu X; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Zhou Y; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Hu Y; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Zhu Q; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. zhuqinn08@163.com.

Journal Article , 2025

Blockade of the vaspin-AP-1 axis inhibits arthritis development.

Jeon J; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea., Cho C; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea.; Center for Systems Biology, Massachusetts General Hospital Research Institute; Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kim S; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea., Kim H; Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Lee H; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea., Kim SJ; Department of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, Republic of Korea., Park H; Department of Bioscience and Biotechnology, Sejong University, Seoul, Republic of Korea., Yu JH; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI hub), Daegu, Republic of Korea., Lee S; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea., Lee KS; Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. ekuse74@kribb.re.kr., Jung J; Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. jjung@kribb.re.kr.; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea. jjung@kribb.re.kr., Yang S; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea. yangsy@skku.edu.

Journal Article , 2025

Degraded products generated by iron stent inhibit the vascular smooth muscle cell proliferation by downregulating AP-1.

Huang J; Department of Cardiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, PR China., Liu B; Department of Neurology, Wuhan Hospital of Traditional Chinese and Western Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China., Zhao C; General ICU/Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, PR China., Li J; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, PR China. Lijing.neurology@aliyun.com., Qiu D; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, PR China. qiudongxu1988@csu.edu.cn.

Journal Article , 2025