Search Results - "Autophagy-lysosome pathway"

Hesperidin Alleviates Hepatic Injury Caused by Deoxynivalenol Exposure through Activation of mTOR and AKT/GSK3β/TFEB Pathways

Wang, Xin^aff1, Chen, Hao^aff1, Jiang, Junze^aff1, Ma, Jun^{aff1, aff2}

Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice

Xin Wang, Wei Wu, Guang Yang, Xue-Wei Yang, Xu Ma, Dan-Dan Zhu, Kabir Ahmad, Khizar Khan, Ying-Zi Wang, Ao-Ran Sui, Song-Yu Guo, Yue Kong, Bo Yuan, Tian-Yuan Luo, Cheng-Kang Liu, Peng Zhang, Yue Zhang, Qi-Fa Li, Bin Wang, Qiong Wu, Xue-Fei Wu, Zhi-Cheng Xiao, Quan-Hong Ma, Shao Li

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First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy–lysosome pathway

Ye Zhong, Jing Xu, Huiying Cao, Jie Gao, Shaoyue Ding, Zhaohui Ren, Huali Yang, Yili Sun, Maosheng Cheng, Jia Li, Yang Liu

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GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy

Liu, Donghua^{j_fzm-2024-0021_aff_001}, Zhang, Yang^{j_fzm-2024-0021_aff_002}, Liu, Xin^{j_fzm-2024-0021_aff_002}, Huang, Qihe^{j_fzm-2024-0021_aff_002}, Zhang, Xiaofang^{j_fzm-2024-0021_aff_002}, Yang, Rui^{j_fzm-2024-0021_aff_002}, Zhao, Yue^{j_fzm-2024-0021_aff_003}, Li, Penghui^{j_fzm-2024-0021_aff_002}, He, Jiayi^{j_fzm-2024-0021_aff_001}, Zhang, Kexiao^{j_fzm-2024-0021_aff_001}, Pan, Zhenwei^{j_fzm-2024-0021_aff_005}, Liu, Huiwen^{j_fzm-2024-0021_aff_001}, Yang, Baofeng^{j_fzm-2024-0021_aff_006}

Mitochondrial dysfunction in Parkinson’s disease

Hattori, Nobutaka^{Aff1, Aff2, IDs00702024028632_cor1}, Sato, Shigeto^{Aff1, Aff3}

Fusobacterium nucleatum downregulated MLH1 expression in colorectal cancer by activating autophagy-lysosome pathway

Tingting Ding, Minkang Wu, Li Zhao, Hu Liu, Xuanke Cao, Jing Guo, Xingchen Zhu, Lamei Zhao, Heping Zhang, Yaohui Gao, Qing Wei

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Innovative discovery and mechanistic validation of HyT-PD ligands for selective CDK9-targeted protein degradation

Yizhan Zhai, Jianfeng Cai

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Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway

Sweeney, Nicholas, Kim, Tae Yeon^{Aff1, Aff2}, Morrison, Cody T., Li, Liangping, Acosta, Diana, Liang, Jiawen, Datla, Nithin V., Fitzgerald, Julie A., Huang, Haoran, Liu, Xianglan, Tan, Gregory Huang, Wu, Min, Karelina, Kate, Bray, Chelsea E., Weil, Zachary M., Scharre, Douglas W., Serrano, Geidy E., Saito, Takashi^{Aff7, Aff8}, Saido, Takaomi C., Beach, Thomas G., Kokiko-Cochran, Olga N.^{Aff1, Aff10}, Godbout, Jonathan P.^{Aff1, Aff10}, Johnson, Gail V. W., Fu, Hongjun^{Aff1, Aff10, IDs00401024028101_cor24}

Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans

Kumar, Arun, Saha, Manti Kumar, Kumar, Vipin, Bhattacharya, Anupam, Barge, Sagar, Mukherjee, Ashis K.^{Aff4, Aff5}, Kalita, Mohan C., Khan, Mojibur R.^{Aff1, IDs1297902400457w_cor8}

Discovery and mechanism verification of first-in-class hydrophobic tagging-based degraders of HBV core protein

Xu, Shujing ^{a, †}, Wang, Ya ^{b, †}, Shi, Dazhou ^a, Wang, Shuo ^a, Qiao, Lijun ^b, Yang, Ge ^b, Zhou, Yang ^a, Liu, Xinyong ^a, Wu, Shuo ^{c, ⁎}, Li, Yuhuan ^{c, ⁎}, Zhan, Peng ^{a, ⁎}

Gene-modified animal models of Parkinson's disease

Peng, Yong ^{a, b, ⁎}, Jiang, Dai-yi ^{a, b}, Yao, Shun-yu ^{a, b}, Zhang, Xiuli ^c, Kazuo, Sugimoto ^{d, e}, Liu, Jia ^{d, e}, Du, Miao-qiao ^{a, b}, Lin, Lan-xin ^{a, b}, Chen, Quan ^{a, b}, Jin, Hong ^{a, b}

Pathogenesis of Parkinson’s disease: from hints from monogenic familial PD to biomarkers

Hattori, Nobutaka^{Aff1, Aff2, Aff3, Aff4, Aff5, IDs00702024027475_cor1}, Funayama, Manabu^{Aff1, Aff2, Aff3}, Imai, Yuzuru^{Aff1, Aff4}, Hatano, Taku

The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity

Wang, Xiaolu ^{1, 2, 3}, Wang, Lingling ^{1, 3}, Zhou, Zhili ^{1, 3}, Jiang, Chenhao ^{1, 3}, Bao, Ziyu ^{1, 3}, Wang, Yuexin ^{1, 2}, Zhang, Ying ¹, Song, Lili ¹, Zhao, Yueling ¹, Li, Xinying ¹, Li, Qianqian ¹, Shen, Yujun ^{1, 2}, Yu, Ying ^{1, 2, ∗}, Mi, Wenyi ^{1, 4, ∗∗}

Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis

Yixian Li, Peng Yang, Ran Meng, Shuting Xu, Lingling Zhou, Kang Qian, Pengzhen Wang, Yunlong Cheng, Dongyu Sheng, Minjun Xu, Tianying Wang, Jing Wu, Jinxu Cao, Qizhi Zhang

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TLR9 regulates the autophagy–lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6‐cGAS‐STING pathway

Ying Liu, Fang‐Zhi Wei, Yu‐Wei Zhan, Ru Wang, Bi‐Yao Mo, Shu‐Dian Lin

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mTOR-dependent TFEB activation and TFEB overexpression enhance autophagy-lysosome pathway and ameliorate Alzheimer's disease-like pathology in diabetic encephalopathy

Lizhen Cheng, Yixin Chen, Donghao Guo, Yuan Zhong, Wei Li, Yijia Lin, Ya Miao

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Autophagy-lysosome pathway alteration in ocular surface manifestations in Fabry disease patients

Marco Marenco, Marco Segatto, Marta Sacchetti, Pietro Mangiantini, Francesca Giovannetti, Rocco Plateroti

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Selective dopaminergic vulnerability in Parkinson’s disease: new insights into the role of DAT

Maged M. Harraz

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Destruction or Reconstruction: A Subtle Liaison between the Proteolytic and Signaling Role of Protein Ubiquitination in Spermatogenesis

Berruti, Giovanna^Aff9

Crusio, Wim E., Series Editor^Aff1, Dong, Haidong, Series Editor^Aff2, Radeke, Heinfried H., Series Editor^Aff3, Rezaei, Nima, Series Editor^Aff4, Steinlein, Ortrud, Series Editor^Aff5, Xiao, Junjie, Series Editor^Aff6, Cheng, C.Yan, editor^Aff7, Sun, Fei, editor^Aff8