Sökresultat - "Brzozowski CF"

Early α-synuclein aggregation decreases corticostriatal glutamate drive and synapse density.

Brzozowski CF; Department of Neurology, Killon Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Challa H; Department of Neurology, Killon Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Gcwensa NZ; Department of Neurology, Killon Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Hall D; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Nabert D; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Chambers N; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Gallardo I; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Millet M; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA., Volpicelli-Daley L; Department of Neurology, Killon Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Moehle MS; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegeneration, and Fixel Institute, University of Florida, Gainesville, FL 32610, USA. Electronic address: mark.moehle@ufl.edu.

Journal Article , 2025

Corrigendum to "Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala" [Neurobiology of Disease 199 (2024) 106595].

Gcwensa NZ; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: gcwenolw@uab.edu., Russell DL; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: dre28@uab.edu., Long KY; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: klonguab@uab.edu., Brzozowski CF; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: cfbrzozo@uab.edu., Liu X; Center for Cellular and Molecular Imaging, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address: xinran.liu@yale.edu., Gamble KL; Department of Psychiatry and Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: karengamble@uabmc.edu., Cowell RM; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: ritacowell@uabmc.edu., Volpicelli-Daley LA; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: lvolpicellidaley@uabmc.edu.

Published Erratum , 2025

Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala.

Gcwensa NZ; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: gcwenolw@uab.edu., Russell DL; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: dre28@uab.edu., Long KY; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: klonguab@uab.edu., Brzozowski CF; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: cfbrzozo@uab.edu., Liu X; Center for Cellular and Molecular Imaging, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address: xinran.liu@yale.edu., Gamble KL; Department of Psychiatry and Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: karengamble@uabmc.edu., Cowell RM; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: ritacowell@uabmc.edu., Volpicelli-Daley LA; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: lvolpicellidaley@uabmc.edu.

Journal Article , 2024

Cortico-amygdala synaptic structural abnormalities produced by templated aggregation of α-synuclein.

Gcwensa NZ, Russell DL, Long KY, Brzozowski CF, Liu X, Gamble KL, Cowell RM, Volpicelli-Daley LA

Preprint; Journal Article , 2024

Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein.

Brzozowski CF; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.; Interfaculty Institute for Biochemistry, University of Tübingen, 72076, Tübingen, Germany., Hijaz BA; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Singh V; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Gcwensa NZ; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Kelly K; Duke Center for Neurodegeneration Research, Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Boyden ES; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., West AB; Duke Center for Neurodegeneration Research, Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Sarkar D; MIT Media Lab, Departments of Biological Engineering and Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Volpicelli-Daley LA; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. lvolpicellidaley@uabmc.edu.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2021