Sökresultat - "Chekler, Eugene P."

Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments

Riehl, Paul S.^aff1, Zhang, Meng Yao^aff1, Dhar, Payal^aff1, Wang, Zhiying^aff2, Pan, Jie^aff2, Mansfield, Kathleen^aff1, Johnson, Walter L.^aff1, Zhang, Qian^aff1, Li, Yvonne^aff1, D’Souza, Ryan^aff2, Zhang, Jun^aff2, Olsen, Jonathan^aff2, Deshpande, Madhura^aff1, Kotapati, Srikanth^aff1, Hollingsworth, Scott A.^aff1, Verma, Isha^aff1, Li, Yi-xin^aff1, Su, Yang^aff1, Cheng, Qinqin^aff1, Yamazoe, Sayumi^aff1, Micci, Luca^aff1, Broz, Miranda^aff1, Janc, James^aff1, Chekler, Eugene P.^aff1, Lo, Julian C.^aff1

Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells

Sega, Emanuela, Kotapati, Srikanth, Poudel, Yam B., Cheng, Qinqin, Sadanala, Keerthi, Schneider, Bridget, Chekler, Eugene P., Rao, Chetana, Gangwar, Sanjeev, Sproul, Tim, Law, Deborah, Broz, Miranda, Strop, Pavel, Yamazoe, Sayumi

Optimization of a micro-scale air–liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2

Sen, Chandani, Rickabaugh, Tammy M, Jeyachandran, Arjit Vijey, Yuen, Constance, Ghannam, Maisam, Durra, Abdo, Aziz, Adam, Castillo, Kristen, Garcia, Gustavo, Purkayastha, Arunima, Han, Brandon, Boulton, Felix W, Chekler, Eugene, Garces, Robert, Wolff, Karen C, Riva, Laura, Kirkpatrick, Melanie G, Gebara-Lamb, Amal, McNamara, Case W, Betz, Ulrich AK, Arumugaswami, Vaithilingaraja, Damoiseaux, Robert, Gomperts, Brigitte N

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Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach

Poudel, Yam B.^aff1, Lo, Julian C.^aff1, Norris, Derek J.^aff2, Cox, Matthew^aff1, He, Liqi^aff1, Johnson, Walter L.^aff1, A. M. Subbaiah, Murugaiah^aff3, Mondal, Santigopal^aff3, Thangavel, Soodamani^aff3, Subramani, Lakshumanan^aff3, Reddy, Maheswara^aff3, Jain, Suraksha^aff3, Weiss, Dahlia R.^aff1, Sivaprakasam, Prasanna^aff2, Critton, David^aff2, Mulligan, Dawn^aff2, Xie, Chunshan^aff2, Dhar, Payal^aff1, Li, Yvonne^aff1, Sega, Emanuela^aff1, Yamazoe, Sayumi^aff1, Gavai, Ashvinikumar V.^aff2, Mathur, Arvind^aff2, Zapf, Christoph W.^aff4, Chekler, Eugene P.^aff1

The New Frontier: Merging Molecular Glue Degrader and Antibody–Drug Conjugate Modalities To Overcome Strategic Challenges

Poudel, Yam B.^aff1, Thakore, Ruchita R.^aff2, Chekler, Eugene P.^aff1

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Correction to 'The New Frontier: Merging Molecular Glue Degrader and Antibody–Drug Conjugate Modalities To Overcome Strategic Challenges'

Poudel, Yam B., Thakore, Ruchita R., Chekler, Eugene P.

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Target validation using chemical probes

Bunnage, Mark E^{Aff1, IDnchembio1197_cor1}, Chekler, Eugene L Piatnitski^{Aff1, IDnchembio1197_cor2}, Jones, Lyn H^{Aff1, IDnchembio1197_cor3}

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The next frontier in drug discovery: Unveiling the pharmacological potential of proximity inducers

Holmberg-Douglas, Natalie ^a, Keenan, Katherine N. ^a, Gonzalez-Lopez de Turiso, Felix ^a, Chekler, Eugene P. ^b, Shanmugasundaram, Veerabahu ^c, Riggs, Jennifer R. ^a, Zapf, Christoph W. ^a

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