Sökresultat - "Computer Simulation"

Computational modelling for improved translation of cardiac inotropic and lusitropic drug effects from rats to humans.

Jung A; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging - Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria. Electronic address: alexander.jung@medunigraz.at., Augustin CM; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging - Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria., Voglhuber-Höller J; BioTechMed-Graz, Graz, Austria; Department of Cardiology, Medical University of Graz, Graz, Austria., Kiessling M; BioTechMed-Graz, Graz, Austria; Department of Cardiology, Medical University of Graz, Graz, Austria., Ljubojevic-Holzer S; BioTechMed-Graz, Graz, Austria; Department of Cardiology, Medical University of Graz, Graz, Austria; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging - Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Mirams GR; Centre for Mathematical Medicine & Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, United Kingdom., Niederer SA; Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom., Plank G; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging - Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria.

Journal Article , 2025

Development of a breast reconstruction-specific computational model to predict shoulder function in breast cancer survivors.

Pataky J; Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA., Graves CL; Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA., Heitzenrater J; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Caru M; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.; Department of Pediatrics, Division of Hematology and Oncology, Penn State College of Medicine, Hershey, PA, USA., Vidt ME; Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA. mzv130@psu.edu.; Department of Physical Medicine and Rehabilitation, Penn State College of Medicine, Hershey, PA, USA. mzv130@psu.edu.

Journal Article , 2025

Heterogeneous network modelling and robustness analysis of production line operation under the influence of design changes.

Yan, Douxi¹ (AUTHOR), Qiu, Zhilong¹ (AUTHOR), Leng, Jiewu¹ (AUTHOR), Zhang, Ding¹ (AUTHOR), Liu, Qiang¹ (AUTHOR) liuqiang@gdut.edu.cn

Optimization of monocrystalline silicon photovoltaic module assembly lines based on simulation model.

Liu Y; College of Materials Science and Engineering, Beijing University of Technology, Beijing, China., Xia X; Yingli Energy (China) Co., Ltd., Baoding, China., Zhang J; College of Materials Science and Engineering, Beijing University of Technology, Beijing, China., Wang K; Yingli Energy (China) Co., Ltd., Baoding, China., Yu B; National Key Laboratory of Photovoltaic Materials and Cells, Yingli Energy Development Co., Ltd., Baoding, China., Wu M; Yingli Energy (China) Co., Ltd., Baoding, China., Shi J; National Key Laboratory of Photovoltaic Materials and Cells, Yingli Energy Development Co., Ltd., Baoding, China., Ma C; Yingli Energy (China) Co., Ltd., Baoding, China., Liu Y; Yingli Energy (China) Co., Ltd., Baoding, China., Hu B; Yingli Energy (China) Co., Ltd., Baoding, China., Wang X; Yingli Energy (China) Co., Ltd., Baoding, China., Wang B; College of Materials Science and Engineering, Beijing University of Technology, Beijing, China., Wang R; College of Materials Science and Engineering, Beijing University of Technology, Beijing, China., Wang B; College of Materials Science and Engineering, Beijing University of Technology, Beijing, China.

Journal Article , 2025

Start & Stop: a PhysiCell and PhysiBoSS 2.0 add-on for interactive simulation control.

Smeriglio R; Department of Control and Computer Engineering, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129, Turin, TO, Italy., Bardini R; Department of Control and Computer Engineering, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129, Turin, TO, Italy. roberta.bardini@polito.it., Savino A; Department of Control and Computer Engineering, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129, Turin, TO, Italy., Di Carlo S; Department of Control and Computer Engineering, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129, Turin, TO, Italy. stefano.dicarlo@polito.it.

Journal Article , 2025

An Open-Science Computational Model of Organelle Acidification to Integrate Putative Mechanisms of Synaptic Vesicle Acidification and Filling.

Baraglia EC; Synthetic Physiology Lab, Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy., Fattorini G; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, Università Politecnica delle Marche, Ancona, Italy.; Center for Neurobiology of Aging, INRCA IRCCS, Ancona, Italy., Chattaraj S; Synthetic Physiology Lab, Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy., Pasqualini F; Synthetic Physiology Lab, Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy. francesco.pasqualini@unipv.it., Conti F; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, Università Politecnica delle Marche, Ancona, Italy.; Center for Neurobiology of Aging, INRCA IRCCS, Ancona, Italy.

Journal Article , 2025

Hands-on practicals in pharmacology teaching at university level: Outpaced by computer-based simulations, or is there a (blended) future?

Wilhelmus MMM; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Anatomy and Neurosciences, Team Education & Innovation, Amsterdam Neuroscience, De Boelelaan 1117, Amsterdam, the Netherlands. Electronic address: m.wilhelmus@amsterdamumc.nl., Drukarch B; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Anatomy and Neurosciences, Team Education & Innovation, Amsterdam Neuroscience, De Boelelaan 1117, Amsterdam, the Netherlands.

Journal Article; Review , 2025

Principal fitted component framework for robust support vector regression based on bounded loss: A simulation study with potential applications.

Tahir A; College of Statistical Sciences, University of the Punjab, Lahore, Pakistan., Ilyas M; College of Statistical Sciences, University of the Punjab, Lahore, Pakistan.

Journal Article , 2025

Numerical simulation study on multifield coupling of enhanced geothermal systems under different fracture characteristics.

Cui H; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China., Jiang X; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China., Mo Z; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China., Guo S; School of Materials Science and Engineering, Chang'an University, Xi'an, China., Zhao C; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China., Zhuang W; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China., Guo F; School of Architecture and Civil Engineering, Anhui Polytechnic University, Wuhu, China.; Engineering Research Center of Anhui Green Building and Digital Construction, Anhui Polytechnic University, Wuhu, China.

Journal Article , 2025

Leveraging large language models in pharmacometrics: evaluation of NONMEM output interpretation and simulation capabilities.

Cha HJ; Department of Pharmacology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, Korea.; PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea., Choe K; Department of Pharmacology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, Korea.; PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea., Shin E; Artificial Intelligence and Clinical Pharmacology Laboratory, Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, 14214-8033, USA., Ramanathan M; Artificial Intelligence and Clinical Pharmacology Laboratory, Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, 14214-8033, USA. murali@buffalo.edu., Han S; Department of Pharmacology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, Korea. shan@catholic.ac.kr.; PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea. shan@catholic.ac.kr.

Journal Article , 2025

Comparing 3 Evidence-Based Strategies to Reduce Cardiovascular Disease Burden: An Individual-Based Cardiometabolic Policy Simulation.

Lutze S; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Bachmeier S; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Bowman A; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., DeCleene N; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Jafari H; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Kappel M; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Kinuthia C; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Lindstedt P; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Lindstrom M; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Mudambi R; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Razo C; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA.; Department of Health Metrics Sciences University of Washington Seattle WA USA., Swedin K; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA., Flaxman A; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA.; Department of Health Metrics Sciences University of Washington Seattle WA USA.; Department of Global Health University of Washington Seattle WA USA., Roth G; Institute for Health Metrics and Evaluation University of Washington Seattle WA USA.; Department of Health Metrics Sciences University of Washington Seattle WA USA.; Division of Cardiology, Department of Medicine University of Washington Seattle WA USA.

Journal Article; Comparative Study , 2025

Nondifferential misclassification of outcome under (near-) perfect specificity: a simulation study.

Ma W; The Robert Larner, MD College of Medicine at the University of Vermont, Burlington, VT 05405, United States., MacLehose RF; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, United States., Lash TL; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States., Collin LJ; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT  84112, United States., Tuo Y; Department of Medicine, The Robert Larner, MD College of Medicine at the University of Vermont, Burlington, VT  05405, United States., Ahern TP; Departments of Surgery and Biochemistry, The Robert Larner, MD College of Medicine at the University of Vermont, Burlington, VT  05405, United States.

Journal Article , 2025

Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in comparing classification methods on high-dimensional data.

Stolte M; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany., Schreck N; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany.; Faculty of Liberal Arts and Sciences, Technical University of Applied Sciences Augsburg, Augsburg, Bavaria, Germany., Slynko A; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada., Saadati M; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany., Benner A; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany., Rahnenführer J; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany., Bommert A; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany.

topic group “High-dimensional data” (TG9) of the STRATOS Initiative

Journal Article; Comparative Study , 2025

Critical Roles for Modeling and Simulation and Real-World Evidence to Inform Challenges in Clinical Trial Diversity Planning.

Kadambi A; Certara USA, Radnor, Pennsylvania, USA., Krekels EHJ; Certara NL, Leiden, the Netherlands., Martinecz A; Certara Canada Corporation, Montreal, Quebec, Canada., Fatzinger G; Certara UK, Sheffield, UK., Jones HM; Certara UK, Sheffield, UK., Khachatryan A; Certara UK, London, UK., Yeo KR; Certara UK, Sheffield, UK., Brown F; Certara USA, Radnor, Pennsylvania, USA.

Journal Article; Review , 2025

In silico modeling of a clinical photon-counting CT system: Verification and validation.

McCabe C; Center for Virtual Imaging Trials, Duke University, Durham, North Carolina, USA., Harrawood B; Center for Virtual Imaging Trials, Duke University, Durham, North Carolina, USA., Samei E; Center for Virtual Imaging Trials, Duke University, Durham, North Carolina, USA., Abadi E; Center for Virtual Imaging Trials, Duke University, Durham, North Carolina, USA.

Journal Article; Validation Study , 2025

High-Dimensional Multiresponse Partially Functional Linear Regression.

Cai X; School of Statistics and Data Science, Nanjing Audit University, Nanjing, China., Cao J; Department of Statistics and Actuarial Science, Simon Fraser University, British Columbia, Canada., Yan X; School of Mathematics and Statistics, Jiangsu Normal University, Xuzhou, China., Zhao P; School of Mathematics and Statistics, Jiangsu Normal University, Xuzhou, China.

Journal Article , 2025

Translation of Animal Study to Human: In Silico Based Development of Implantable Pulmonary Artery Pressure Sensor.

Goubergrits L; Institute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany., Yevtushenko P; Institute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany., Schlief A; Institute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany., Romberg J; Biotronik, Berlin, Germany., Kuehne T; Institute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany., Arndt A; Biotronik, Berlin, Germany.; Technische Universität Dresden, Dresden, Germany., Bruening J; Institute of Computer-Assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany.

Journal Article , 2025

Femoral bone growth predictions based on personalized multi-scale simulations: validation and sensitivity analysis of a mechanobiological model.

Koller W; Department of Biomechanics, Kinesiology and Computer Science in Sport, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria. willi.koller@univie.ac.at.; Neuromechanics Research Group, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria. willi.koller@univie.ac.at.; Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, University of Vienna, Vienna, Austria. willi.koller@univie.ac.at., Svehlik M; Department of Orthopedics and Traumatology, Medical University of Graz, Graz, Austria., Wallnöfer E; Department of Biomechanics, Kinesiology and Computer Science in Sport, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria.; Neuromechanics Research Group, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria.; Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, University of Vienna, Vienna, Austria., Kranzl A; Laboratory for Gait and Human Movements, Orthopaedic Hospital Speising, Vienna, Austria.; Vienna Bone and Growth Center, Vienna, Austria., Mindler G; Department of Pediatric Orthopaedics, Orthopaedic Hospital Speising, Vienna, Austria.; Vienna Bone and Growth Center, Vienna, Austria., Baca A; Department of Biomechanics, Kinesiology and Computer Science in Sport, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria., Kainz H; Department of Biomechanics, Kinesiology and Computer Science in Sport, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria.; Neuromechanics Research Group, Centre for Sport Science and University Sports, University of Vienna, Vienna, Austria.

Journal Article; Validation Study , 2025

The impact of extended reality simulators on ophthalmic surgical training and performance: a systematic review and meta-analysis of 17,623 eyes.

Yang L; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Al-Ani A; Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB, Canada. aalani@ucalgary.ca., Bondok MS; Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB, Canada., Gooi P; Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB, Canada., Chung H; Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB, Canada.

Journal Article; Systematic Review; Meta-Analysis , 2025

Computational construction and design optimization of a novel tri-tube heart valve.

Li J; Department of Biomedical Engineering, University of Minnesota, 7-114 NHH, 312 Church St SE, Minneapolis, MN, 55455, USA.; Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA., Yu Y; Department of Biomedical Engineering, University of Minnesota, 7-114 NHH, 312 Church St SE, Minneapolis, MN, 55455, USA., Tranquillo RT; Department of Biomedical Engineering, University of Minnesota, 7-114 NHH, 312 Church St SE, Minneapolis, MN, 55455, USA. tranquillo@umn.edu.; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, USA. tranquillo@umn.edu.

Journal Article , 2025