Sökresultat - "Cyclization"

The catalytic asymmetric polyene cyclization of homofarnesol to ambrox.

Luo N; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Turberg M; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Leutzsch M; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Mitschke B; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Brunen S; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Wakchaure VN; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Nöthling N; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany., Schelwies M; Synthesis and Homogeneous Catalysis, BASF SE, Ludwigshafen, Germany., Pelzer R; New Business Development Aroma Ingredients, BASF SE, Ludwigshafen, Germany., List B; Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany. list@kofo.mpg.de.

Journal Article , 2024

Crystal Structure and Catalytic Mechanism of the cis-Eunicellane Cyclase AriE.

Li FR; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., Yang Q; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., He J; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., Sun X; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., Pan X; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., Xu HM; The Public Laboratory Platform, China Pharmaceutical University, Nanjing, 211198, China., Rudolf JD; Department of Chemistry, University of Florida, Gainesville, Florida, 32611-7011, United States., Dong LB; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.

Journal Article , 2025

An overview: total synthesis of arborisidine, and arbornamine.

Yadav G; Department of Chemistry, Indira Gandhi University, Meerpur, Rewari, Haryana, 122502, India.; Department of Chemistry, Baba Mastnath University Asthal bohar, Rohtak, Haryana, 124021, India., Megha; Department of Chemistry, Indira Gandhi University, Meerpur, Rewari, Haryana, 122502, India., Yadav S; Department of Chemistry, Netaji Subhas University of Technology, Dwarka, Delhi, 110078, India., Tomar R; Department of Chemistry, SRM Institute of Science & Technology, Delhi-NCR Campus, Modinagar, Ghaziabad, 201204, India. ravitomar451@gmail.com.; Department of Chemical Engineering, Indian Institute of Technology Delhi, Delhi, 110016, India. ravitomar451@gmail.com.

Journal Article; Review , 2025

Mechanism of cyclization-degradation of silazanes: A DFT study.

Ding YQ; School of Chemistry and Chemical Engineering, Qilu University of Technology, Jinan, Shandong, 250353, PR China. Electronic address: dyq@qlu.edu.cn., Mou QH; Advanced Materials Institute, Shandong Academy of Science, Jinan, Shandong, 250014, PR China., Wang T; School of Chemistry and Chemical Engineering, Qilu University of Technology, Jinan, Shandong, 250353, PR China., Zhang J; School of Chemistry and Chemical Engineering, Qilu University of Technology, Jinan, Shandong, 250353, PR China.

Journal Article , 2025

Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation.

Yang W; Department of Ocean Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China., Feng X; Department of Ocean Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China., Chen H; Department of Ocean Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China., Liman GLS; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523., Santangelo TJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523., Zhang C; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801., Zeng Z; Department of Ocean Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China.

Journal Article , 2025

High Bendability of Short RNA-DNA Hybrid Duplex Revealed by Single-Molecule Cyclization and Molecular Dynamics Simulations.

Wu B; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China., Tian F; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China., Yang Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China., Dai L; Department of Physics, City University of Hong Kong, Hong Kong, China., Zhang X; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China.

Journal Article , 2025

Cyclization of Short Peptides Designed from Late Embryogenesis Abundant Protein to Improve Stability and Functionality.

Wu Y; Department of Biological Functions Engineering, Kyushu Institute of Technology, Kitakyushu Science and Research Park, Kitakyushu, Fukuoka, Japan., Ikeno S; Department of Biological Functions Engineering, Kyushu Institute of Technology, Kitakyushu Science and Research Park, Kitakyushu, Fukuoka, Japan.

Journal Article , 2025

Total Syntheses of Bryostatins 1, 7, 9 and 9-N 3 .

Guo Q; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Yang Y; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Zhang H; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Wang D; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Li B; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Jiang D; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Tu X; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Gao X; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Zhang C; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Qin Y; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Gao L; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Wang W; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China., Song Z; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced, Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.

Journal Article , 2025

A Review of Approaches Developed for Spiroether Synthesis.

Ahmadpourmir H; Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Taghizadeh SF; Applied Biomedical Research Center, Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran., Mezhuev Y; A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Vavilov Street, 28, 119991, Moscow, Russia.; Department of Biomaterials, Mendeleev University of Chemical Technology of Russia, Miusskaya Sq., 9, 125047, Moscow, Russia., Salavati Nik AA; Department of Horticultural Sciences and Landscape Architecture, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran., Tzatzarakis M; Laboratory of Toxicology, Medical School, University of Crete, Heraklion, Crete, Greece., Tsatsakis A; Laboratory of Toxicology, Medical School, University of Crete, Heraklion, Crete, Greece., Rezaee R; Applied Biomedical Research Center, Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran. raminrezaee1983@gmail.com.

Journal Article; Review , 2025

Indolylamide Macrocyclization by a Streptococcus pneumoniae ThiF-like Enzyme Family Member.

Rajput A; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States., Butler KS; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States., Springer DA; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States., Chekan JR; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States.

Journal Article , 2025

Gold-Catalyzed Conia-Ene Cyclization/Aza-Michael Addition Cascades: Access to Indolinylazepinone PNPs with Anticancer Activity.

Ling X; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Wang J; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Chen Y; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Zhao P; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Ni D; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Wei Y; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., Nie S; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), Department of Urology of the Second Affiliated Hospital & College of Pharmacy, Chongqing Medical University, Chongqing 400016, China., He Y; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.

Journal Article , 2025

Structural Basis for Medium-Chain Dehydrogenase/Reductase-Catalyzed Reductive Cyclization in Polycyclic Tetramate Macrolactam Biosynthesis.

Xie X; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Li F; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Mu Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Lu M; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Luo J; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Wang H; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, People's Republic of China., Shen Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China.; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, People's Republic of China., Du L; Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, United States., Zhu D; School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China., Li Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, People's Republic of China.

Journal Article , 2025

Structure of bifunctional variediene synthase yields unique insight on biosynthetic diterpene assembly and cyclization.

Wenger ES; Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, PA, USA., Christianson DW; Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, PA, USA. chris@sas.upenn.edu.

Journal Article , 2025

Synthesis of Stylissamide B, a Pro-Rich Cyclic Heptapeptide Isolated From the Marine Sponge Stylissa caribica.

Li Y; Department of Chemistry and Biological Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata, Japan., Ling H; Department of Chemistry and Biological Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata, Japan., Teruya K; Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan., Konno H; Department of Chemistry and Biological Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata, Japan.

Journal Article , 2025

Construction of 1,6-anhydro-functionalized carbohydrate-fused spiro-chromanones via intramolecular domino/spirocyclization.

Jankowski N; Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, United States., Hager C; Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, United States., Arcure H; Department of Chemistry & Biochemistry, Wilkes University, 84 W. South Street, Wilkes-Barre, PA, 18766, United States., Lopez J; Department of Chemistry & Biochemistry, Wilkes University, 84 W. South Street, Wilkes-Barre, PA, 18766, United States., Barrios Gomez AM; Department of Chemistry & Biochemistry, Wilkes University, 84 W. South Street, Wilkes-Barre, PA, 18766, United States., Witczak ZJ; Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, United States. Electronic address: zbigniew.witczak@wilkes.edu., Bielski R; Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, United States., Mencer DE; Department of Chemistry & Biochemistry, Wilkes University, 84 W. South Street, Wilkes-Barre, PA, 18766, United States.

Journal Article , 2025

Biomimetic 1,2-amino migration via photoredox catalysis.

Fan W; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Cui Y; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Zhan B; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Chen Y; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Bao L; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Liang Y; Early TDE Discovery, Oncology R&D, AstraZeneca, Waltham, MA, USA., Zhang X; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. xiahengz@ucas.ac.cn.

Journal Article , 2025

Cyclization of the Analgesic α-Conotoxin Vc1.1 With a Non-Natural Linker: Effects on Structure, Stability, and Bioactivity.

Zhang Y; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, QLD, Australia., Tae HS; Molecular Horizons/Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia., Adams DJ; Molecular Horizons/Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia., Durek T; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, QLD, Australia., Craik DJ; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, QLD, Australia.

Journal Article , 2025

Helicity-Dependent Enzymatic Peptide Cyclization.

Durukan C; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute of Molecular and Life Sciences, VU University Amsterdam, Amsterdam, Netherlands., Faierson J; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands., van der Wal I; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands., Pérez JL; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute of Molecular and Life Sciences, VU University Amsterdam, Amsterdam, Netherlands., Hennig S; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute of Molecular and Life Sciences, VU University Amsterdam, Amsterdam, Netherlands., Grossmann TN; Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute of Molecular and Life Sciences, VU University Amsterdam, Amsterdam, Netherlands.

Journal Article , 2025

Non-enzymatic methylcyclization of alkenes.

Plangger I; Department of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria., Schmidhammer E; Department of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria., Schaar S; Department of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria., Wurst K; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Podewitz M; Department of Materials Chemistry, TU Wien, Vienna, Austria. maren.podewitz@tuwien.ac.at., Magauer T; Department of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria. thomas.magauer@uibk.ac.at.

Journal Article , 2025

Total Synthesis of (-)-Illisimonin A Enabled by Pattern Recognition and Olefin Transposition.

Xu B; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Zhang Z; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Dai M; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.; Department of Pharmacology and Chemical Biology, School of Medicine, Emory University, Atlanta, Georgia 30322, United States.

Journal Article , 2025