Sökresultat - "D'Andrea, Alan D."

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Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs

Swift, Michelle L, Zhou, Rui, Syed, Aleem, Moreau, Lisa A, Tomasik, Bartłomiej, Tainer, John A, Konstantinopoulos, Panagiotis A, D’Andrea, Alan D, He, Yizhou Joseph, Chowdhury, Dipanjan

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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression

Diossy, Miklos^{Aff1, Aff2}, Tisza, Viktoria^{Aff2, Aff3}, Li, Hua^{Aff4, Aff5}, Sahgal, Pranshu^{Aff2, Aff3, Aff6}, Zhou, Jia, Sztupinszki, Zsofia^{Aff1, Aff2}, Young, Denise^{Aff4, Aff5}, Nousome, Darryl^{Aff4, Aff5}, Kuo, Claire^{Aff4, Aff5}, Jiang, Jiji^{Aff4, Aff5}, Chen, Yongmei^{Aff4, Aff5}, Ebner, Reinhard, Sesterhenn, Isabell A., Moncur, Joel T., Chesnut, Gregory T., Petrovics, Gyorgy^{Aff4, Aff5}, Klus, Gregory T.^{Aff2, Aff10}, Valcz, Gabor, Nuzzo, Pier Vitale^{Aff3, Aff12}, Ribli, Dezso, Börcsök, Judit, Prosz, Aurel, Krzystanek, Marcin, Ried, Thomas, Szuts, David, Rizwan, Kinza, Kaochar, Salma, Pathania, Shailja^{Aff16, Aff17}, D’Andrea, Alan D.^{Aff7, Aff18}, Csabai, Istvan, Srivastava, Shiv^{Aff4, Aff19}, Freedman, Matthew L.^{Aff3, Aff6, Aff12, IDs41698024007058_cor32}, Dobi, Albert^{Aff4, Aff5, IDs41698024007058_cor33}, Spisak, Sandor^{Aff14, IDs41698024007058_cor34}, Szallasi, Zoltan^{Aff1, Aff2, Aff20, IDs41698024007058_cor35}

USP1 inhibition: A journey from target discovery to clinical translation

Torrado, Carlos ^a, Ashton, Nicholas W. ^b, D'Andrea, Alan D. ^{b, c}, Yap, Timothy A. ^{a, ⁎}

Isolation of Cytokine-Inducible Genes from Hematopoietic Cells by Differential Display

Zhu, Yuan^Aff3, Hahn, Tom^Aff3, D’Andrea, Alan D.^Aff3

Liang, Peng^Aff1, Pardee, Arthur B.^Aff2, Walker, John M.

The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway

Harada, Naoya, Asada, Shuhei, Jiang, Lige, Nguyen, Huy, Moreau, Lisa, Marina, Ryan J., Adelman, Karen, Iyer, Divya R., D’Andrea, Alan D.

CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair

Li, Feng^{Aff1, IDs41467025568346_cor1}, Zhang, Tianpeng, Syed, Aleem, Elbakry, Amira, Holmer, Noella, Nguyen, Huy^{Aff1, Aff3}, Mukkavalli, Sirisha, Greenberg, Roger A., D’Andrea, Alan D.^{Aff1, Aff3, IDs41467025568346_cor2}

CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining

Iyer, Divya Ramalingam, Harada, Naoya, Clairmont, Connor, Jiang, Lige, Martignetti, David, Nguyen, Huy, He, Yizhou Joseph, Chowdhury, Dipanjan, D’Andrea, Alan D.

Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

Patterson-Fortin, Jeffrey^{Aff1, Aff2}, Jadhav, Heta, Pantelidou, Constantia^{Aff1, Aff9}, Phan, Tin, Grochala, Carter^{Aff3, Aff10}, Mehta, Anita K.^{Aff4, Aff11}, Guerriero, Jennifer L., Wulf, Gerburg M., Wolpin, Brian M.^{Aff1, Aff2, Aff6}, Stanger, Ben Z., Aguirre, Andrew J.^{Aff1, Aff2, Aff6}, Cleary, James M.^{Aff1, Aff2, Aff6}, D’Andrea, Alan D.^{Aff3, Aff8}, Shapiro, Geoffrey I.^{Aff1, Aff2, Aff8, IDs41467023438030_cor14}

RETRACTED ARTICLE: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

Patterson-Fortin, Jeffrey^{Aff1, Aff2}, Jadhav, Heta, Pantelidou, Constantia^{Aff1, Aff9}, Phan, Tin, Grochala, Carter^{Aff3, Aff10}, Mehta, Anita K.^{Aff4, Aff11}, Guerriero, Jennifer L., Wulf, Gerburg M., Wolpin, Brian M.^{Aff1, Aff2, Aff6}, Stanger, Ben Z., Aguirre, Andrew J.^{Aff1, Aff2, Aff6}, Cleary, James M.^{Aff1, Aff2, Aff6}, D’Andrea, Alan D.^{Aff3, Aff8}, Shapiro, Geoffrey I.^{Aff1, Aff2, Aff8, IDs41467023370966_cor14}

Targeting replication stress in cancer therapy

da Costa, Alexandre André B. A., Chowdhury, Dipanjan, Shapiro, Geoffrey I., D’Andrea, Alan D.^{Aff1, Aff3, IDs41573022005585_cor4}, Konstantinopoulos, Panagiotis A.^{Aff2, IDs41573022005585_cor5}

A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2

Dubois, Emilie L, Guitton-Sert, Laure, Béliveau, Mariline, Parmar, Kalindi, Chagraoui, Jalila, Vignard, Julien, Pauty, Joris, Caron, Marie-Christine, Coulombe, Yan, Buisson, Rémi, Jacquet, Karine, Gamblin, Clémence, Gao, Yuandi, Laprise, Patrick, Lebel, Michel, Sauvageau, Guy, d’Andrea, Alan D, Masson, Jean-Yves

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CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair

Li, Feng ¹, Sarangi, Prabha ¹, Iyer, Divya Ramalingam ¹, Feng, Hanrong ¹, Moreau, Lisa ¹, Nguyen, Huy ^{1, 2}, Clairmont, Connor ¹, D’Andrea, Alan D. ^{1, 2, 3, ∗}

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

Pouliot, Gayle P, Degar, James, Hinze, Laura, Kochupurakkal, Bose, Vo, Chau D, Burns, Melissa A, Moreau, Lisa, Ganesa, Chirag, Roderick, Justine, Peirs, Sofie, Menten, Bjorn, Loh, Mignon L, Hunger, Stephen P, Silverman, Lewis B, Harris, Marian H, Stevenson, Kristen E, Weinstock, David M, Weng, Andrew P, Van Vlierberghe, Pieter, D’Andrea, Alan D, Gutierrez, Alejandro

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Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours

Konstantinopoulos, Panagiotis A.^{Aff1, IDs41416021016648_cor1}, Cheng, Su-Chun, Supko, Jeffrey G., Polak, Madeline, Wahner-Hendrickson, Andrea E., Ivy, S. Percy, Bowes, Brittany, Sawyer, Hannah, Basada, Patrice, Hayes, Martin, Curtis, Jennifer, Horowitz, Neil, Wright, Alexi A., Campos, Susana M., Ivanova, Elena V., Paweletz, Cloud P., Palakurthi, Sangeetha, Liu, Joyce F., D’Andrea, Alan D., Gokhale, Prafulla C., Chowdhury, Dipanjan, Matulonis, Ursula A., Shapiro, Geoffrey I.

p31 comet promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase

Sarangi, Prabha, Clairmont, Connor S., Galli, Lucas D., Moreau, Lisa A., D’Andrea, Alan D.

REV7 directs DNA repair pathway choice

Clairmont, Connor S., D’Andrea, Alan D.

The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair

Adeyemi, Richard O., Willis, Nicholas A., Elia, Andrew E.H., Clairmont, Connor, Li, Shibo, Wu, Xiaohua, D’Andrea, Alan D., Scully, Ralph, Elledge, Stephen J.