Search Results - "Eckardt, Jan‑Niklas"

Generating Reliable Synthetic Clinical Trial Data: The Role of Hyperparameter Optimization and Domain Constraints

Hahn, Waldemar, Eckardt, Jan-Niklas, Röllig, Christoph, Sedlmayr, Martin, Middeke, Jan Moritz, Wolfien, Markus

Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations

Eckardt, Jan‑Niklas, Stölzel, Friedrich, Kunadt, Desiree, Röllig, Christoph, Stasik, Sebastian, Wagenführ, Lisa, Jöhrens, Korinna, Kuithan, Friederike, Krämer, Alwin, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Kunzmann, Volker, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Herbst, Regina, Hänel, Mathias, Hanoun, Maher, Kaiser, Ulrich, Kaufmann, Martin, Rácil, Zdenek, Mayer, Jiri, Kroschinsky, Frank, Berdel, Wolfgang E., Ehninger, Gerhard, Serve, Hubert, Müller‑Tidow, Carsten, Platzbecker, Uwe, Baldus, Claudia D., Schetelig, Johannes, Bornhäuser, Martin, Thiede, Christian, Middeke, Jan Moritz

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Deep learning identifies Acute Promyelocytic Leukemia in bone marrow smears

Eckardt, Jan‑Niklas, Schmittmann, Tim, Riechert, Sebastian, Kramer, Michael, Shekh Sulaiman, Anas, Sockel, Katja, Kroschinsky, Frank, Schetelig, Johannes, Wagenführ, Lisa, Schuler, Ulrich, Platzbecker, Uwe, Thiede, Christian, Stölzel, Friedrich, Röllig, Christoph, Bornhäuser, Martin, Wendt, Karsten, Middeke, Jan Moritz

201; info:eu-repo/grantAgreement/Technische Universität Dresden/MeDDrive/60499 //Machine Learning for advanced integrated diagnostics in hematological malignancies

How I diagnose and treat patients in the pre-fibrotic phase of primary myelofibrosis (pre-PMF) - practical approaches of a German expert panel discussion in 2024

Griesshammer, Martin, Al-Ali, Haifa Kathrin, Eckardt, Jan-Niklas^{Aff3, Aff4}, Fiegl, Michael, Göthert, Joachim, Jentsch-Ullrich, Kathleen, Koschmieder, Steffen^{Aff8, Aff9}, Kvasnicka, Hans Michael, Reiter, Andreas, Schmidt, Burkhard, Heidel, Florian H.^{Aff13, Aff14, Aff15, Aff16, IDs00277025061917_cor1}

The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions

Ma, Jun, Xie, Ronald, Ayyadhury, Shamini, Ge, Cheng, Gupta, Anubha, Gupta, Ritu, Gu, Song, Zhang, Yao, Lee, Gihun, Kim, Joonkee, Lou, Wei, Li, Haofeng, Upschulte, Eric, Dickscheid, Timo, de Almeida, José Guilherme, Wang, Yixin, Han, Lin, Yang, Xin, Labagnara, Marco, Gligorovski, Vojislav, Scheder, Maxime, Rahi, Sahand Jamal, Kempster, Carly, Pollitt, Alice, Espinosa, Leon, Mignot, Tâm, Middeke, Jan Moritz, Eckardt, Jan-Niklas, Li, Wangkai, Li, Zhaoyang, Cai, Xiaochen, Bai, Bizhe, Greenwald, Noah F., Van Valen, David, Weisbart, Erin, Cimini, Beth A., Cheung, Trevor, Brück, Oscar, Bader, Gary D., Wang, Bo

How to customize common data models for rare diseases: an OMOP-based implementation and lessons learned

Ahmadi, Najia^{Aff1, IDs13023024033129_cor1}, Zoch, Michele, Guengoeze, Oya, Facchinello, Carlo, Mondorf, Antonia, Stratmann, Katharina, Musleh, Khader, Erasmus, Hans-Peter, Tchertov, Jana, Gebler, Richard, Schaaf, Jannik, Frischen, Lena S., Nasirian, Azadeh, Dai, Jiabin, Henke, Elisa, Tremblay, Douglas, Srisuwananukorn, Andrew, Bornhäuser, Martin, Röllig, Christoph, Eckardt, Jan-Niklas^{Aff8, Aff9}, Middeke, Jan Moritz^{Aff8, Aff9}, Wolfien, Markus^{Aff1, Aff10}, Sedlmayr, Martin

Large language models and multimodal foundation models for precision oncology

Truhn, Daniel, Eckardt, Jan-Niklas^{Aff2, Aff3}, Ferber, Dyke^{Aff4, Aff5}, Kather, Jakob Nikolas^{Aff2, Aff3, Aff4, Aff5, IDs41698024005732_cor4}

Mimicking clinical trials with synthetic acute myeloid leukemia patients using generative artificial intelligence

Eckardt, Jan-Niklas^{Aff1, Aff2, IDs4174602401076x_cor1}, Hahn, Waldemar^{Aff3, Aff4}, Röllig, Christoph, Stasik, Sebastian, Platzbecker, Uwe, Müller-Tidow, Carsten, Serve, Hubert, Baldus, Claudia D., Schliemann, Christoph, Schäfer-Eckart, Kerstin, Hanoun, Maher, Kaufmann, Martin, Burchert, Andreas, Thiede, Christian, Schetelig, Johannes, Sedlmayr, Martin, Bornhäuser, Martin^{Aff1, Aff14, Aff15}, Wolfien, Markus^{Aff3, Aff4}, Middeke, Jan Moritz^{Aff1, Aff2}

Validation of the revised 2022 European LeukemiaNet risk stratification in adult patients with acute myeloid leukemia

Ruhnke, Leo ^{1, ∗}, Bill, Marius ^{1, 2, 3, 4}, Zukunft, Sven ¹, Eckardt, Jan-Niklas ^{1, 2, 5}, Schäfer, Silvia ^{2, 3}, Stasik, Sebastian ¹, Hanoun, Maher ⁶, Schroeder, Thomas ⁶, Fransecky, Lars ⁷, Steffen, Björn ⁸, Krause, Stefan W. ⁹, Scholl, Sebastian ¹⁰, Hochhaus, Andreas ¹⁰, Sauer, Tim ¹¹, Kraus, Sabrina ¹², Schäfer-Eckart, Kerstin ¹³, Kaufmann, Martin ¹⁴, Jost, Edgar ¹⁵, Brümmendorf, Tim ¹⁵, Schliemann, Christoph ¹⁶, Mikesch, Jan-Henrik ¹⁶, Krug, Utz ¹⁷, Hänel, Mathias ¹⁸, Morgner, Anke ¹⁸, Schaich, Markus ¹⁹, Neubauer, Andreas ²⁰, Repp, Roland ²¹, Niemann, Dirk ²², Seggewiss-Bernhardt, Ruth ²³, Meinhardt, Achim ²⁴, Kullmer, Johannes ²⁵, Kaiser, Ulrich ²⁶, Blau, Wolfgang ²⁷, Kiani, Alexander ²⁸, Grigoleit, Götz Ulrich ²⁹, Giagounidis, Aristoteles ³⁰, Wurm, Alexander A. ^{1, 2, 3, 4}, Altmann, Heidi ¹, Middeke, Jan Moritz ¹, Schetelig, Johannes ¹, Müller-Tidow, Carsten ^{11, 31}, Stölzel, Friedrich ⁷, Baldus, Claudia D. ⁷, Platzbecker, Uwe ³², Serve, Hubert ⁸, Bornhäuser, Martin ^{1, 2, 3, 4}, Thiede, Christian ^{1, 33}, Röllig, Christoph ¹

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Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia

Eckardt, Jan-Niklas^{Aff1, IDs41375023020611_cor1}, Stasik, Sebastian, Röllig, Christoph, Petzold, Andreas, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Kunzmann, Volker, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Herbst, Regina, Hänel, Mathias, Hanoun, Maher, Kaiser, Ulrich, Kaufmann, Martin, Rácil, Zdenek, Mayer, Jiri, Oelschlägel, Uta, Berdel, Wolfgang E., Ehninger, Gerhard, Serve, Hubert, Müller-Tidow, Carsten, Platzbecker, Uwe, Baldus, Claudia D., Dahl, Andreas, Schetelig, Johannes^{Aff1, Aff21}, Bornhäuser, Martin^{Aff1, Aff22, Aff23}, Middeke, Jan Moritz, Thiede, Christian

Secondary-type mutations do not impact outcome in NPM1-mutated acute myeloid leukemia – implications for the European LeukemiaNet risk classification

Eckardt, Jan-Niklas, Bill, Marius^{Aff1, Aff2, Aff3, Aff4}, Rausch, Christian, Metzeler, Klaus, Spiekermann, Karsten, Stasik, Sebastian, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H., Krug, Utz, Wörmann, Bernhard, Hiddemann, Wolfgang, Görlich, Dennis, Sauerland, Cristina, Steffen, Björn, Einsele, Hermann, Neubauer, Andreas, Burchert, Andreas, Schäfer-Eckart, Kerstin, Berdel, Wolfgang E., Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Hanoun, Maher, Kaufmann, Martin, Fransecky, Lars, Braess, Jan, Ruhnke, Leo, Schetelig, Johannes, Middeke, Jan Moritz, Serve, Hubert, Baldus, Claudia D., Platzbecker, Uwe, Müller-Tidow, Carsten, Bornhäuser, Martin^{Aff1, Aff2, Aff3, Aff4}, Herold, Tobias, Thiede, Christian, Röllig, Christoph^{Aff1, IDs41375023020166_cor40}

Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology

Kerle, Irina A.^{Aff1, Aff2, Aff3, IDs41698024007883_cor1}, Gross, Thomas^Aff4, Kögler, Anja, Arnold, Jonas S., Werner, Maximilian^{Aff1, Aff2, Aff3}, Eckardt, Jan-Niklas^{Aff6, Aff7}, Möhrmann, Elena E.^{Aff1, Aff2, Aff3}, Arlt, Marie, Hutter, Barbara, Hüllein, Jennifer, Richter, Daniela^{Aff1, Aff2, Aff9}, Schneider, Martin M. K., Hlevnjak, Mario, Möhrmann, Lino^{Aff1, Aff2, Aff3}, Hanf, Dorothea^{Aff1, Aff2, Aff3}, Heilig, Christoph E.^{Aff10, Aff11}, Kreutzfeldt, Simon, Teleanu, Maria-Veronica^{Aff10, Aff11}, Schröck, Evelin^{Aff4, Aff5}, Hübschmann, Daniel^{Aff8, Aff12, Aff13, Aff14}, Horak, Peter, Heining, Christoph^{Aff1, Aff2, Aff3}, Fröhling, Stefan^{Aff10, Aff12, Aff15}, Glimm, Hanno^{Aff1, Aff2, Aff3, Aff9}

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An overview and a roadmap for artificial intelligence in hematology and oncology

Rösler, Wiebke, Altenbuchinger, Michael, Baeßler, Bettina, Beissbarth, Tim, Beutel, Gernot, Bock, Robert, von Bubnoff, Nikolas, Eckardt, Jan-Niklas^{Aff7, Aff8}, Foersch, Sebastian, Loeffler, Chiara M. L.^{Aff7, Aff8}, Middeke, Jan Moritz^{Aff7, Aff8}, Mueller, Martha-Lena, Oellerich, Thomas, Risse, Benjamin, Scherag, André, Schliemann, Christoph, Scholz, Markus, Spang, Rainer, Thielscher, Christian, Tsoukakis, Ioannis, Kather, Jakob Nikolas^{Aff7, Aff8, Aff19, IDs00432023046675_cor21}

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The future landscape of large language models in medicine

Clusmann, Jan^{Aff1, Aff2}, Kolbinger, Fiona R.^{Aff1, Aff3}, Muti, Hannah Sophie^{Aff1, Aff3}, Carrero, Zunamys I., Eckardt, Jan-Niklas^{Aff1, Aff4}, Laleh, Narmin Ghaffari^{Aff1, Aff2}, Löffler, Chiara Maria Lavinia^{Aff1, Aff4}, Schwarzkopf, Sophie-Caroline, Unger, Michaela, Veldhuizen, Gregory P., Wagner, Sophia J.^{Aff5, Aff6}, Kather, Jakob Nikolas^{Aff1, Aff2, Aff4, Aff7, IDs43856023003701_cor12}

UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome

Georgi, Julia-Annabell, Stasik, Sebastian, Eckardt, Jan-Niklas, Zukunft, Sven, Hartwig, Marita, Röllig, Christoph, Middeke, Jan Moritz, Oelschlägel, Uta, Krug, Utz, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D., Kaufmann, Martin, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Ehninger, Gerhard, Bornhäuser, Martin^{Aff1, Aff21}, Schetelig, Johannes^{Aff1, Aff22}, Kroschinsky, Frank, Thiede, Christian^{Aff1, Aff23, IDs4140802300858y_cor36}

Unsupervised meta-clustering identifies risk clusters in acute myeloid leukemia based on clinical and genetic profiles

Eckardt, Jan-Niklas^{Aff1, Aff2, IDs43856023002986_cor1}, Röllig, Christoph, Metzeler, Klaus, Heisig, Peter, Stasik, Sebastian, Georgi, Julia-Annabell, Kroschinsky, Frank, Stölzel, Friedrich, Platzbecker, Uwe, Spiekermann, Karsten, Krug, Utz, Braess, Jan, Görlich, Dennis, Sauerland, Cristina, Woermann, Bernhard, Herold, Tobias, Hiddemann, Wolfgang, Müller-Tidow, Carsten^{Aff10, Aff11}, Serve, Hubert, Baldus, Claudia D., Schäfer-Eckart, Kerstin, Kaufmann, Martin, Krause, Stefan W., Hänel, Mathias, Berdel, Wolfgang E., Schliemann, Christoph, Mayer, Jiri, Hanoun, Maher, Schetelig, Johannes, Wendt, Karsten^{Aff2, Aff4}, Bornhäuser, Martin^{Aff1, Aff11, Aff21}, Thiede, Christian, Middeke, Jan Moritz^{Aff1, Aff2}

Alterations of cohesin complex genes in acute myeloid leukemia: differential co-mutations, clinical presentation and impact on outcome

Eckardt, Jan-Niklas^{Aff1, Aff2, IDs41408023007901_cor1}, Stasik, Sebastian, Röllig, Christoph, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Kunzmann, Volker, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Herbst, Regina, Hänel, Mathias, Hanoun, Maher, Kaiser, Ulrich, Kaufmann, Martin, Rácil, Zdenek, Mayer, Jiri, Cerqueira, Tiago, Kroschinsky, Frank, Berdel, Wolfgang E., Serve, Hubert, Müller-Tidow, Carsten, Platzbecker, Uwe, Baldus, Claudia D., Schetelig, Johannes^{Aff1, Aff21}, Siepmann, Timo^{Aff2, Aff22}, Bornhäuser, Martin^{Aff1, Aff23, Aff24}, Middeke, Jan Moritz, Thiede, Christian