Sökresultat - "Extrusion"

Preparation of self-dispersible eutectic mixtures for poorly soluble drugs: Hot-melt extrusion vs. melt casting.

Schlosser P; Technische Universität Braunschweig, Institut für Pharmazeutische Technologie und Biopharmazie, Mendelssohnstraße 1, 38106 Braunschweig, Germany; Technische Universität Braunschweig, Zentrum für Pharmaverfahrenstechnik, Franz-Liszt-Straße 35A, 38106 Braunschweig, Germany., Bunjes H; Technische Universität Braunschweig, Institut für Pharmazeutische Technologie und Biopharmazie, Mendelssohnstraße 1, 38106 Braunschweig, Germany; Technische Universität Braunschweig, Zentrum für Pharmaverfahrenstechnik, Franz-Liszt-Straße 35A, 38106 Braunschweig, Germany. Electronic address: heike.bunjes@tu-braunschweig.de.

Journal Article; Comparative Study , 2025

Comparative evaluation of four traction scenarios on a labially impacted dilacerated maxillary central incisor: a three-dimensional finite element analysis.

Alyafrusee ES; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China.; Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dentistry, Ibb University, IBB, Yemen., Zheng B; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China. bwzheng@cmu.edu.cn.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China. bwzheng@cmu.edu.cn., Telha W; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Thamar University, Thamar, Yemen., Li M; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China., Wu H; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China., Yang X; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China., Almaqrami BS; Department of Orthodontics, Ningbo Dental Hospital, Ningbo, Zhejiang, 315032, China.; Orthodontics Division, Faculty of Medicine and Health Sciences, Taiz University, Taiz, Yemen., Al-Worafi NA; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China., Al-Somairi MAA; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China.; Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dentistry, Ibb University, IBB, Yemen., Alhammadi MS; Orthodontics and Dentofacial Orthopedics, Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia., Liu Y; Department of Orthodontics, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Disease, China Medical University, Shenyang, Liaoning, 110002, China. liuyi@cmu.edu.cn.; Shenyang Clinical Medical Research Center of Orthodontic Disease, Shenyang, Liaoning, 110002, China. liuyi@cmu.edu.cn.

Journal Article; Comparative Study , 2025

Comparative study of Hot-Melt Extrusion, spray drying, and KinetiSol® processing to formulate a poorly water-soluble and thermolabile drug.

Jara MO; Molecular Pharmaceutics and Drug Delivery Division, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA., Behrend-Keim B; Molecular Pharmaceutics and Drug Delivery Division, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA., Bedogni G; Instituto de Química Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas (IQUIR-CONICET), Suipacha 531, Rosario 2000, Argentina; Área Técnica Farmacéutica, Departamento de Farmacia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Suipacha 531, Universidad Nacional de Rosario, Rosario 2000, Argentina., Michelena LV; Instituto de Química Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas (IQUIR-CONICET), Suipacha 531, Rosario 2000, Argentina; Área Técnica Farmacéutica, Departamento de Farmacia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Suipacha 531, Universidad Nacional de Rosario, Rosario 2000, Argentina., Davis DA Jr; AustinPx, 111 W. Cooperative Way, Georgetown, TX 78626, USA., Miller DA; AustinPx, 111 W. Cooperative Way, Georgetown, TX 78626, USA., Salomon C; Instituto de Química Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas (IQUIR-CONICET), Suipacha 531, Rosario 2000, Argentina; Área Técnica Farmacéutica, Departamento de Farmacia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Suipacha 531, Universidad Nacional de Rosario, Rosario 2000, Argentina., Williams RO 3rd; Molecular Pharmaceutics and Drug Delivery Division, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA. Electronic address: bill.williams@austin.utexas.ed.

Journal Article; Comparative Study , 2025

Orodispersible films prepared by hot-melt extrusion versus solvent casting.

Reuther M; AdhexPharma, 42-44 Rue de Longvic, 21300 Chenôve, France; Univ. Bourgogne Franche-Comté, L'Institut Agro, Université Bourgogne Europe, INRAE, UMR PAM 1517, 21000 Dijon, France., Rollet N; AdhexPharma, 42-44 Rue de Longvic, 21300 Chenôve, France., Debeaufort F; Univ. Bourgogne Franche-Comté, L'Institut Agro, Université Bourgogne Europe, INRAE, UMR PAM 1517, 21000 Dijon, France; Université Bourgogne Europe, IUT-Dijon-Auxerre, Dpt BioEngineering, 7 blvd Docteur Petitjean, 20178 Dijon Cedex, France., Chambin O; Univ. Bourgogne Franche-Comté, L'Institut Agro, Université Bourgogne Europe, INRAE, UMR PAM 1517, 21000 Dijon, France; Université Bourgogne Europe, Faculty of Health Sciences, Dpt of Pharmaceutical Technology, Bd Jeanne d'Arc, 21000 Dijon, France. Electronic address: odile.chambin@ube.fr.

Journal Article; Comparative Study , 2025

Identification and Characterization of Interaction Product Impurities and Degradation Products of Atorvastatin Hot Melt Extrusion Formulation Using LC-HRMS/MS and ATR-IR.

Mittal A; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India., Aras G; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India., Yuvaraaj VK; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India., Badgujar D; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India., Benival D; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India., Sharma N; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujarat, India.

Journal Article , 2025

Orthodontic extrusion with fixed appliances for treatment of intrusive luxation injuries: A prospective study of 28 permanent maxillary incisors.

Zhang J; Department of Paediatric Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Wang N; Department of Paediatric Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.; Department of Stomatology, Peking University Third Hospital, Beijing, China., Gao X; Department of Orthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Qin M; Department of Paediatric Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Journal Article , 2025

Exploration of Conventional and FDM-Mediated 3D Printed Tablets Fabricated Using HME-Based Filaments for pH-Dependent Drug Delivery.

Patil R; Department of Pharmaceutical Technology (Formulations), National Institute of Pharmaceutical Education and Research, Sila Village, Changsari, Kamrup District, Guwahati, Assam, India, 781101., Bule P; Department of Pharmaceutical Technology (Formulations), National Institute of Pharmaceutical Education and Research, Sila Village, Changsari, Kamrup District, Guwahati, Assam, India, 781101., Chella N; Department of Pharmaceutical Technology (Formulations), National Institute of Pharmaceutical Education and Research, Sila Village, Changsari, Kamrup District, Guwahati, Assam, India, 781101. naveen@niperguwahati.in.

Journal Article , 2025

Stability and recrystallization of amorphous solid dispersions prepared by hot-melt extrusion and spray drying.

Martynek D; Department of Chemical Engineering, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6, Dejvice, Czech Republic; Zentiva, k.s., Ukabelovny 130, 10237 Prague 10, Czech Republic., Ridvan L; Zentiva, k.s., Ukabelovny 130, 10237 Prague 10, Czech Republic., Sivén M; Division of Pharmaceutical Chemistry and Technology, University of Helsinki, Viikinkaari 5 E, 00014, Helsinki, Finland; Helsinki Institute of Sustainability Science, HELSUS, Finland., Šoóš M; Department of Chemical Engineering, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6, Dejvice, Czech Republic. Electronic address: soosm@vscht.cz.

Journal Article , 2025

Exploring the impact of material selection on the efficacy of hot-melt extrusion.

Kapoor DU; Dr. Dayaram Patel Pharmacy College, Bardoli 394601, Gujarat, India., Vaishnav DJ; CK Pithawala Institute of Pharmaceutical Education and Research, Surat 395007, Gujarat, India., Garg R; Asian College of Pharmacy, Udaipur 313001, Rajasthan, India., Saini PK; Department of Pharmaceutics, Sri Balaji College of Pharmacy, Jaipur 302026, Rajasthan, India., Prajapati BG; Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva 384012, Gujarat, India. Electronic address: bhupendra.prajapati@ganpatuniversity.ac.in., Castro GR; Nanomedicine Research Unit, Center for Natural and Human Sciences, Federal University of ABC, Santo André, Sao Paulo 09210-580, Brazil., Suttiruengwong S; Sustainable Materials Laboratory, Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakhon Pathom 73000, Thailand., Limmatvapirat S; Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Sriamornsak P; Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand; Academy of Science, The Royal Society of Thailand, Bangkok 10300, Thailand; Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, Tamil Nadu, India. Electronic address: sriamornsak_p@su.ac.th.

Journal Article; Review , 2025

Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusion.

Keßler L; Soft Matter Chemistry, Department of Chemistry, and Helsinki Institute of Sustainability Science, Faculty of Science, University of Helsinki, Helsinki 00014, Finland., Mishra R; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland., Hietala S; Department of Chemistry, University of Helsinki, P.O. Box 55, Helsinki FIN-00014, Finland., Lammens M; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland; Laboratory of Pharmaceutical Technology, Ghent University, Ghent 9000, Belgium., Peltonen L; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland., Rades T; Department of Pharmacy, University of Copenhagen, Copenhagen 2100, Denmark., van Veen B; Pharmaceutical Sciences, Orion Corporation, Espoo 02200, Finland., Juppo A; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland., Laaksonen T; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland; Faculty of Engineering and Natural Sciences, Tampere University, Tampere 33101, Finland., Strachan C; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland., Luxenhofer R; Soft Matter Chemistry, Department of Chemistry, and Helsinki Institute of Sustainability Science, Faculty of Science, University of Helsinki, Helsinki 00014, Finland. Electronic address: robert.luxenhofer@helsinki.fi.

Journal Article , 2025

Digital orthodontic extrusion system for complex crown-root fracture of anterior teeth: A technique report.

Sun A; Attending Faculty, Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, Hangzhou, PR China; Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, PR China., Feng X; Attending Faculty, Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, Hangzhou, PR China., Chen L; Associate Professor, Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing, PR China., Gu X; Professor, Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, Hangzhou, PR China. Electronic address: 610964127@qq.com.

Journal Article , 2024

Investigation of the Influence of Copovidone Properties and Hot-Melt Extrusion Process on Level of Impurities, In Vitro Release, and Stability of an Amorphous Solid Dispersion Product.

Saraf I; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria., Jakasanovski O; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.; Product Development, Lek Pharmaceuticals d.d., Verovškova 57, 1526 Ljubljana, Slovenia., Stanić T; Product Development, Lek Pharmaceuticals d.d., Verovškova 57, 1526 Ljubljana, Slovenia., Kralj E; Product Development, Lek Pharmaceuticals d.d., Verovškova 57, 1526 Ljubljana, Slovenia., Petek B; Product Development, Lek Pharmaceuticals d.d., Verovškova 57, 1526 Ljubljana, Slovenia., Williams JD; Institute of Chemistry, University of Graz, NAWI Graz, Heinrichstrasse 28, 8010 Graz, Austria.; Center for Continuous Flow Synthesis and Processing (CCFLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, 8010 Graz, Austria., Dmytro N; Institute of Physical and Theoretical Chemistry, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria., Georg G; Institute of Physical and Theoretical Chemistry, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria., Bernd W; Institute of Chemistry, University of Graz, Heinrichstr. 28, 8010 Graz, Austria., Klaus Z; Institute of Chemistry, University of Graz, Heinrichstr. 28, 8010 Graz, Austria., Perhavec P; Product Development, Lek Pharmaceuticals d.d., Verovškova 57, 1526 Ljubljana, Slovenia., German Ilić I; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia., Paudel A; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.; Institute of Process and Particle Engineering, Graz University of Technology, 8010 Graz, Austria., Kushwah V; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.

Journal Article , 2024

Role of rheology in formulation and process design of hot melt extruded amorphous solid dispersions.

Badruddoza AZM; Pharmaceutical Sciences Small Molecule, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA. Electronic address: abuzayedmd.badruddoza@pfizer.com., Moseson DE; Pharmaceutical Sciences Small Molecule, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA., Lee HG; Pharmaceutical Sciences Small Molecule, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA., Esteghamatian A; Pharmaceutical Sciences Small Molecule, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA., Thipsay P; Pharmaceutical Sciences Small Molecule, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA.

Journal Article; Review , 2024

Upgrading Extrusion Process for the Production of Croutons: Optimization and Quality Characteristics.

Rokalla, Preethi¹ (AUTHOR), Dikkala, Praveen Kumar² (AUTHOR), Pandurangrao, Bobade Hanuman¹ (AUTHOR), Sridhar, Kandi³ (AUTHOR), Singh, Baljit¹ (AUTHOR) baljit@pau.edu, Sharma, Minaxi⁴ (AUTHOR) minaxi86sharma@gmail.com, Hebishy, Essam (AUTHOR) ehebishy+eic@wiley.com

Development of poly (lactic-co-glycolic acid) (PLGA) based implants using hot melt extrusion (HME) for sustained release of drugs: The impacts of PLGA's material characteristics.

Yang F; Ashland Specialty Ingredients, Wilmington, DE, USA. Electronic address: fyyang@ashland.com., Stahnke R; Ashland Specialty Ingredients, Wilmington, DE, USA., Lawal K; Ashland Specialty Ingredients, Wilmington, DE, USA., Mahnen C; Ashland Specialty Ingredients, Wilmington, DE, USA., Duffy P; Ashland Specialty Ingredients, Wilmington, DE, USA., Xu S; Ashland Specialty Ingredients, Wilmington, DE, USA., Durig T; Ashland Specialty Ingredients, Wilmington, DE, USA.

Journal Article , 2024

The Impact of Orthodontic Extrusion on Keratinized Gingiva.

Arsić I; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Marinković N; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Pajević T; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Marković J; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Dragović M; School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Stamenković Z; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Stefanović N; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia., Nedeljković N; Clinic for Orthodontics, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Journal Article , 2024

Computer-assisted open exposure of palatally impacted canines for orthodontic eruption: A randomized clinical trial.

Kivovics M; Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40. 1088 Budapest, Hungary. Electronic address: kivovics.marton@semmelweis.hu., Szanyi SM; Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40. 1088 Budapest, Hungary., Takács A; Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40. 1088 Budapest, Hungary., Répási M; Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40. 1088 Budapest, Hungary., Németh O; Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40. 1088 Budapest, Hungary., Mijiritsky E; Department of Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, School of Medicine, Tel-Aviv University, Tel Aviv 64239, Israel; Goldschleger School of Dental Medicine, Faculty of Medicine, Tel-Aviv University, Tel Aviv 39040, Israel.

Journal Article; Randomized Controlled Trial , 2024

The role of lignin extracted from patchouli fiber waste in sustainable ternary biopolymer blends.

Muhammad, Syaifullah^1,2 syaiful.muhammad@usk.ac.id, Bairwan, Rahul Dev³, Abdul Khalil, H. P. S.⁴, M., Marwan¹, Baharudin, Mohd Syukri⁵, Ahmad, Mardiana Idayu^5,6

Analysis of the Wear of Forming Tools in the Process of Extruding Ceramic Bands Using Selected Research Methods for Evaluating Operational Durability.

Hawryluk, Marek¹ (AUTHOR) marek.hawryluk@pwr.edu.pl, Marzec, Jan^1,2 (AUTHOR), Leśniewski, Tadeusz¹ (AUTHOR), Krawczyk, Justyna^1,2 (AUTHOR), Madej, Łukasz² (AUTHOR), Perzyński, Konrad² (AUTHOR)

The Influence of Grain Structure on Mechanical Properties of LPBF AlSi10Mg Alloy Obtained via Conventional and KOBO Extrusion Process.

Snopiński, Przemysław¹ (AUTHOR) przemyslaw.snopinski@polsl.pl, Ostachowski, Paweł² (AUTHOR), Matus, Krzysztof³ (AUTHOR), Żaba, Krzysztof⁴ (AUTHOR)