Search Results - "Felsenfeld DP"

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Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons.

Stocksdale JT; Department of Neurobiology and Behavior, UC Irvine, Irvine, CA 92677, USA., Leventhal MJ; MIT PhD Program in Computational and Systems Biology, Cambridge, MA 02139, USA; MIT Department of Biological Engineering, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Lam S; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Xu YX; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Wang YO; Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Wang KQ; Department of Neurobiology and Behavior, UC Irvine, Irvine, CA 92677, USA., Thomas R; Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA 94158, USA., Faghihmonzavi Z; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Raghav Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Smith C; Department of Psychiatry and Human Behavior, UC Irvine, Irvine, CA 92697, USA., Wu J; Department of Biological Chemistry, UC Irvine, Irvine, CA 92697, USA., Miramontes R; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA., Sarda K; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Johnston H; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Shin MG; Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA 94158, USA., Huang T; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Foster M; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Barch M; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Amirani N; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Paiz C; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Easter L; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Duderstadt E; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA., Vaibhav V; Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Sundararaman N; Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Felsenfeld DP; CHDI Management, Inc, New York, NY 10001, USA., Vogt TF; CHDI Management, Inc, New York, NY 10001, USA., Van Eyk J; Advanced Clinical Biosystems Research Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Finkbeiner S; Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA 94158, USA; Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurology, University of California San Francisco, San Francisco, CA 94158, USA; Taube/Koret Center for Neurodegenerative Disease Research, Gladstone Institutes, San Francisco, CA 94158, USA., Kaye JA; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158, USA; Taube/Koret Center for Neurodegenerative Disease Research, Gladstone Institutes, San Francisco, CA 94158, USA., Fraenkel E; MIT PhD Program in Computational and Systems Biology, Cambridge, MA 02139, USA; MIT Department of Biological Engineering, Cambridge, MA 02139, USA., Thompson LM; Department of Neurobiology and Behavior, UC Irvine, Irvine, CA 92677, USA; Department of Psychiatry and Human Behavior, UC Irvine, Irvine, CA 92697, USA; Department of Biological Chemistry, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA. Electronic address: lmthomps@uci.edu.

Journal Article , 2025

Author Correction: Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Galimberti M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Nucera MR; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Stem Cell Biology Department; Murdoch Children's Research Institute, Parkville, VIC, 3052, Australia., Bocchi VD; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Center for Stem Cell Biology and Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Conforti P; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Vezzoli E; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; ALEMBIC Advanced Light and Electron Microscopy BioImaging Center, San Raffaele Scientific Institute, DIBIT 1, Via Olgettina 58, 20132, Milan, Italy., Cereda M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Maffezzini C; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Iennaco R; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Scolz A; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Falqui A; Department of Physics 'Aldo Pontremoli', University of Milan, Via Celoria 16, 20133, Milan, Italy., Cordiglieri C; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Cremona M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Swiss Stem Cell Foundation, Via Petrini 2, 6900, Lugano, Switzerland., Espuny-Camacho I; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; GIGA-Neuroscience, Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, C.H.U. Sart Tilman, 4000, Liège, Belgium., Faedo A; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Axxam, OpenZone, Via Meucci 3, 20091, Bresso, Milan, Italy., Felsenfeld DP; CHDI Management/CHDI Foundation, New York, NY, USA., Vogt TF; CHDI Management/CHDI Foundation, New York, NY, USA., Ranzani V; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Zuccato C; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Besusso D; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Cattaneo E; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy. elena.cattaneo@unimi.it.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy. elena.cattaneo@unimi.it.

Published Erratum , 2025

Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Galimberti M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Nucera MR; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Stem Cell Biology Department; Murdoch Children's Research Institute, Parkville, VIC, 3052, Australia., Bocchi VD; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Center for Stem Cell Biology and Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Conforti P; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Vezzoli E; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; ALEMBIC Advanced Light and Electron Microscopy BioImaging Center, San Raffaele Scientific Institute, DIBIT 1, Via Olgettina 58, 20132, Milan, Italy., Cereda M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Maffezzini C; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Iennaco R; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Scolz A; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Falqui A; Department of Physics 'Aldo Pontremoli', University of Milan, Via Celoria 16, 20133, Milan, Italy., Cordiglieri C; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Cremona M; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Swiss Stem Cell Foundation, Via Petrini 2, 6900, Lugano, Switzerland., Espuny-Camacho I; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; GIGA-Neuroscience, Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, C.H.U. Sart Tilman, 4000, Liège, Belgium., Faedo A; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Axxam, OpenZone, Via Meucci 3, 20091, Bresso, Milan, Italy., Felsenfeld DP; CHDI Management/CHDI Foundation, New York, NY, USA., Vogt TF; CHDI Management/CHDI Foundation, New York, NY, USA., Ranzani V; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Zuccato C; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Besusso D; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Cattaneo E; Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases, Department of Biosciences, University of Milan, 20122, Milan, Italy. elena.cattaneo@unimi.it.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy. elena.cattaneo@unimi.it.

Journal Article , 2024

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).

Li MM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America., Lau Z; Integrated Screening Core, Experimental Therapeutics Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Cheung P; Integrated Screening Core, Experimental Therapeutics Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Aguilar EG; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America., Schneider WM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America., Bozzacco L; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America., Molina H; Proteomics Resource Center, The Rockefeller University, New York, New York, United States of America., Buehler E; Trans-NIH RNAi Screening Facility, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, Maryland, United States of America., Takaoka A; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America., Felsenfeld DP; Integrated Screening Core, Experimental Therapeutics Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., MacDonald MR; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2017

Suramin inhibits cullin-RING E3 ubiquitin ligases.

Wu K; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029;, Chong RA; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029;, Yu Q; Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou 310029, Zhejiang, China;, Bai J; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical College, Xuzhou, 221002, China;, Spratt DE; Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London N6A 5C1, ON, Canada;, Ching K; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029;, Lee C; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029;, Miao H; Department of Pharmacology, University of Washington, Seattle, WA 98195; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195;, Tappin I; Program in Molecular Biology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021;, Hurwitz J; Program in Molecular Biology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021; j-hurwitz@ski.mskcc.org zhen-qiang.pan@mssm.edu., Zheng N; Department of Pharmacology, University of Washington, Seattle, WA 98195; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195;, Shaw GS; Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London N6A 5C1, ON, Canada;, Sun Y; Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou 310029, Zhejiang, China; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109;, Felsenfeld DP; Department of Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, NY 10029;, Sanchez R; Department of Structural and Chemical Biology, The Icahn School of Medicine at Mount Sinai, New York, NY 10029., Zheng JN; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical College, Xuzhou, 221002, China;, Pan ZQ; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical College, Xuzhou, 221002, China; j-hurwitz@ski.mskcc.org zhen-qiang.pan@mssm.edu.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2016