Search Results - "Frontotemporal lobar degeneration"

WDR49-Positive Astrocytes Mark Severity of Neurodegeneration in Frontotemporal Lobar Degeneration and Alzheimer's Disease.

Rajicic A; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Giannini LAA; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Gerrits E; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., van Buuren R; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Melhem S; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Slotman JA; Department of Pathology and Erasmus Optical Imaging Center, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Rozemuller AJM; Department of Pathology, Amsterdam Neuroscience, Amsterdam University Medical Center, Amsterdam, The Netherlands., Eggen BJL; Department of Biomedical Sciences of Cells & Systems, Section of Molecular Neurobiology, University of Groningen and University Medical Center Groningen, Groningen, Netherlands., van Swieten JC; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Seelaar H; Department of Neurology and Alzheimer Centre Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

Journal Article , 2025

Clinical and Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP-43 A and B.

Coulborn S; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Schafer R; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Roy ARK; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Sokolowski A; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Cryns NG; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Leichter D; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Lago AL; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Ramos EM; Department of Neurology, University of California, Los Angeles, California, USA., Cobigo Y; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Spina S; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Grinberg LT; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA.; Department of Pathology, University of California, San Francisco, California, USA., Geschwind DH; Department of Neurology, University of California, Los Angeles, California, USA.; Department of Human Genetics, University of California, Los Angeles, California, USA.; Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, California, USA., Gorno-Tempini ML; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Kramer JH; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Rosen HJ; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Miller BL; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Seeley WW; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA.; Department of Pathology, University of California, San Francisco, California, USA., Perry DC; Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA.

Journal Article , 2025

Disclosure of plasma p-tau217 measure improves diagnostic confidence in patients with Alzheimer's disease versus syndromes associated with frontotemporal lobar degeneration.

Cantoni V; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Cotelli MS; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy., Rota M; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Alberici A; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy., Libri I; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy., Huber H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; German Center of Neurodegenerative Diseases (DZNE), Bonn, Germany., Tan K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Ghidoni R; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio, Fatebenefratelli, Brescia, Italy., Bellini S; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio, Fatebenefratelli, Brescia, Italy., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Shatin, Hong Kong, China., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, P.R. China., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; Banner Sun Health Research Institute, Sun City, Arizona, USA.; Banner Alzheimer's Institute and University of Arizona, Phoenix, Arizona, USA., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio, Fatebenefratelli, Brescia, Italy.

Journal Article , 2025

Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing.

Faura J; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Heeman B; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Pottier C; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St Louis, MO, USA., Baker MC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., DeJesus-Hernandez M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Küçükali F; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Heiß L; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Wynants S; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Van den Broeck M; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., De Rijk P; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Neuromics Support Facility, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., De Pooter T; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Neuromics Support Facility, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Joris G; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Neuromics Support Facility, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Finch NA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Asmann Y; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Strazisar M; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Neuromics Support Facility, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Oskarsson B; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Sleegers K; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Josephs KA; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Nguyen AT; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Reichard RR; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Graff-Radford NR; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., van Blitterswijk M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Rademakers R; Applied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium. rosa.rademakers@uantwerpen.be.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. rosa.rademakers@uantwerpen.be.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. rosa.rademakers@uantwerpen.be.

Journal Article , 2025

GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration.

Hughes LE; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK., Adams NE; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Rouse MA; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK., Naessens M; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK., Shaw A; Psychology Department, University of Exeter, Exeter, UK., Murley AG; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK., Cope TE; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK., Holland N; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK., Nesbitt D; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK., Street D; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK., Whiteside DJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK., Rowe JB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK.; Cambridge University Hospitals, Cambridge, UK.

Journal Article , 2025

Microbial Composition, Disease Trajectory and Genetic Background in a Slow Onset Model of Frontotemporal Lobar Degeneration.

Daude N; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 8M8, Canada., Machado I; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 8M8, Canada., Arce L; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 8M8, Canada., Yang J; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 8M8, Canada., Westaway D; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 8M8, Canada.

Journal Article , 2025

LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP.

Shahidehpour RK; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Neuroscience, University of Kentucky, Lexington, KY, USA., Katsumata Y; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Biostatistics, University of Kentucky, Lexington, KY, 40536, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Ghayal NB; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Aung KZ; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Biostatistics, University of Kentucky, Lexington, KY, 40536, USA., Wu X; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Biostatistics, University of Kentucky, Lexington, KY, 40536, USA., Phe P; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA., Jicha GA; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Neurology, University of Kentucky, Lexington, KY, 40536, USA., Neltner AM; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA., Archer JRC; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA., Corrada MM; Department of Neurology, University of California, Irvine, CA, USA.; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA., Kawas CH; Department of Neurology, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Ahmad Sajjadi S; Department of Neurology, University of California, Irvine, CA, USA.; Department of Pathology and Laboratory Medicine, University of California, Irvine, CA, USA., Woodworth DC; Department of Neurology, University of California, Irvine, CA, USA., Bukhari SA; Department of Pathology, Stanford University, Stanford, CA, USA., Montine TJ; Department of Pathology, Stanford University, Stanford, CA, USA., Fardo DW; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA.; Department of Biostatistics, University of Kentucky, Lexington, KY, 40536, USA., Nelson PT; Sanders-Brown Center On Aging, University of Kentucky, Rm 575 Lee Todd Jr Bldg/U. Kentucky, 789 S. Limestone Ave, Lexington, KY, 40536, USA. peter.nelson@uky.edu.; Department of Neuroscience, University of Kentucky, Lexington, KY, USA. peter.nelson@uky.edu.; Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Kentucky, Lexington, KY, 40536, USA. peter.nelson@uky.edu.

Journal Article , 2025

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.

Pottier C; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. cpottier@wustl.edu.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. cpottier@wustl.edu.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium. cpottier@wustl.edu.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA. cpottier@wustl.edu.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St Louis, MO, USA. cpottier@wustl.edu., Küçükali F; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Baker M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Batzler A; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Jenkins GD; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., van Blitterswijk M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Vicente CT; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., De Coster W; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Wynants S; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Van de Walle P; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Faura J; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Haggarty SJ; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., van Rooij JG; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands., Mol MO; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands., Hsiung GR; Department of Medicine, Division of Neurology, University of British Columbia, Vancouver, BC, Canada., Graff C; Division of Neurogeriatrics, Karolinska Institutet, Solna, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital, Solna, Sweden., Öijerstedt L; Division of Neurogeriatrics, Karolinska Institutet, Solna, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital, Solna, Sweden., Neumann M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Neuropathology, University of Tübingen, Tübingen, Germany., Asmann Y; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA., McDonnell SK; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Baheti S; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Josephs KA; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Whitwell JL; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Bieniek KF; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; University of Texas Health Science Center San Antonio, San Antonio, TX, USA., Forsberg L; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Heuer H; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Lago AL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Geier EG; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Yokoyama JS; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Oddi AP; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Flanagan M; University of Texas Health Science Center San Antonio, San Antonio, TX, USA., Mao Q; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Hodges JR; Central Clinical School and Brain and Mind Centre, University of Sydney, Sydney, NSW, Australia., Kwok JB; University of Sydney, Sydney, NSW, Australia.; NeuRA, University of New South Wales, Randwick, NSW, Australia., Domoto-Reilly K; Department of Neurology, University of Washington, Seattle, WA, USA., Synofzik M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division Translational Genomics of Neurodegenerative Diseases, Center for Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Wilke C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division Translational Genomics of Neurodegenerative Diseases, Center for Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Onyike C; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Dickerson BC; Department of Neurology, Case Western Reserve University, Cleveland, OH, USA., Evers BM; Division of Neuropathology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Dugger BN; Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA, USA., Munoz DG; St. Michael's Hospital, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Keith J; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Zinman L; Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Rogaeva E; Krembil Discovery Tower, Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON, Canada., Suh E; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Gefen T; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, IL, USA., Geula C; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, IL, USA., Weintraub S; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, IL, USA., Diehl-Schmid J; Department of Psychiatry and Psychotherapy, Technical University of Munich, Munich, Germany.; kbo-Inn-Salzach-Klinikum, Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Wasserburg/Inn, Germany., Farlow MR; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA., Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Woodruff BK; Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA., Caselli RJ; Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA., Donker Kaat LL; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands., Huey ED; Department of Psychiatry and Human Behavior, Brown Alpert Medical School, Brown University, Providence, RI, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA., Mead S; MRC Prion Unit at University College London, Institute of Prion Diseases, London, UK., King A; Department of Basic and Clinical Neuroscience, London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Department of Clinical Neuropathology, King's College Hospital NHS Foundation Trust, London, UK., Roeber S; Centre for Neuropathology and Prion Research, Ludwig-Maximilians-University of Munich, Munich, Germany., Nana AL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Knopman DS; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Uitti RJ; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Ramos EM; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Grinberg LT; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Tempini MLG; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Rosen HJ; Department of Pathology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Spina S; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Piguet O; School of Psychology and Brain and Mind Centre, University of Sydney, Sydney, SWA, Australia., Grossman M; Department of Neurology, Penn Frontotemporal Degeneration Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Trojanowski JQ; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Keene CD; University of Washington BioRepository and Integrated Neuropathology (BRaIN) lab, Harborview Medical Center, Seattle, WA, USA., Jin LW; M.I.N.D. Institute Laboratory, University of California, Davis Medical Center, Sacramento, CA, USA., Prudlo J; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Neurology, Rostock University Medical Center, Rostock, Germany., Geschwind DH; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Rissman RA; Alzheimer's Therapeutic Research Institute, Keck School of Medicine of the University of Southern California, San Diego, CA, USA., Cruchaga C; Department of Psychiatry, Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO, USA., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Halliday GM; University of Sydney, Sydney, NSW, Australia., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, USA., Serrano GE; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, USA., Arzberger T; Centre for Neuropathology and Prion Research, Ludwig-Maximilians-University of Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany., Herms J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Centre for Neuropathology and Prion Research, Ludwig-Maximilians-University of Munich, Munich, Germany., Boxer AL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Honig LS; Department of Neurology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Vonsattel JP; Department of Pathology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Lopez OL; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Kofler J; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., White CL 3rd; Division of Neuropathology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Gearing M; Department of Pathology and Laboratory Medicine and Department of Neurology, Emory University, Atlanta, GA, USA., Glass J; Department of Pathology and Laboratory Medicine and Department of Neurology, Emory University, Atlanta, GA, USA., Rohrer JD; Department of Neurodegenerative Disease, Dementia Research Centre, University College London, Queen Square Institute of Neurology, London, UK., Irwin DJ; Department of Neurology, Penn Frontotemporal Degeneration Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Lee EB; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Van Deerlin V; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Castellani R; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Mesulam MM; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, IL, USA., Tartaglia MC; Krembil Discovery Tower, Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON, Canada., Finger EC; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Troakes C; Department of Basic and Clinical Neuroscience, London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Al-Sarraj S; Department of Basic and Clinical Neuroscience, London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; King's College Hospital NHS Foundation Trust, London, UK., Dalgard CL; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Miller BL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Seelaar H; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands., Graff-Radford NR; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Mackenzie IR; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., van Swieten JC; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands., Seeley WW; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Sleegers K; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Biernacka JM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA., Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. rosa.rademakers@uantwerpen.vib.be.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. rosa.rademakers@uantwerpen.vib.be.; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium. rosa.rademakers@uantwerpen.vib.be.

Journal Article , 2025

Regional cerebral blood flow correlated with aphasia in dementia of the Alzheimer's type and frontotemporal lobar degeneration.

Ota M; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan., Koshibe Y; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan., Kitabatake A; Department of Clinical Psychology, University of Tsukuba Hospital, Ibaraki, Japan., Tamura M; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan., Takahashi T; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan., Nemoto K; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan., Arai T; Department of Psychiatry, Division of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.

Journal Article , 2025

aFTLD-U presenting with primary progressive aphasia suggestive of non-fluent type with apraxia of speech.

Patira R; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh,PA, USA., Shahabadi AZ; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Lopez O; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh,PA, USA., Kofler J; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh,PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

Journal Article; Case Reports , 2025

Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer's disease.

Veverová K; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Katonová A; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Horáková H; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Laczó J; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Angelucci F; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Hort J; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic., Lautrup S; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, 1478, Norway.; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway., Fang EF; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, 1478, Norway. e.f.fang@medisin.uio.no.; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway. e.f.fang@medisin.uio.no., Vyhnálek M; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic. martin.vyhnalek@lfmotol.cuni.cz.

Journal Article , 2025

Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar degeneration.

Malpetti M; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Swann P; Department of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK., Tsvetanov KA; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK.; Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK., Chouliaras L; Department of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK., Strauss A; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Chikaura T; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Murley AG; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal S-431 80, Sweden.; Wallenberg Centre for Molecular Medicine, University of Gothenburg, Gothenburg S-413 45, Sweden.; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Institute Clinical Neuroscience Institute, London SE5 9RT, UK.; NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation, London SE5 8AF, UK., Barker P; NIHR Cambridge Biomedical Research Centre, Core Biochemical Assay Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK., Jones PS; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Fryer TD; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Hong YT; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Cope TE; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK.; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK., Savulich G; Department of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK., Street D; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Bevan-Jones WR; Department of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK., Rittman T; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal S-431 80, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal S-431 80, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal S-431 80, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal S-431 80, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London WC1N 6BG, UK.; UK Dementia Research Institute at UCL, London WC1N 6BG, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Aigbirhio FI; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., O'Brien JT; Department of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK., Rowe JB; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK.; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK.

Journal Article , 2025

Plasma p-tau 217 and neurofilament/p-tau 217 ratio in differentiating Alzheimer's disease from syndromes associated with frontotemporal lobar degeneration.

Benussi A; Neurology Unit, Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Huber H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden., Tan K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden., Cantoni V; Cognitive and Behavioural Neurology Unit, Department of Continuity of Care and Frailty, ASST Spedali Civili di Brescia, Brescia, Italy., Rivolta J; Cognitive and Behavioural Neurology Unit, Department of Continuity of Care and Frailty, ASST Spedali Civili di Brescia, Brescia, Italy., Cotelli MS; Cognitive and Behavioural Neurology Unit, Department of Continuity of Care and Frailty, ASST Spedali Civili di Brescia, Brescia, Italy., Benedet AL; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, P.R. China., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute, Department of Molecular Neuroscience, UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Division of Life Science, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden.; Banner Sun Health Research Institute, Sun City, Arizona, USA.; Banner Alzheimer's Institute, Phoenix, Arizona, USA., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.

Journal Article , 2025

Predicting survival rate by plasma biomarkers and clinical variables in syndromes associated with frontotemporal lobar degeneration.

Cotelli MS; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy., Tarantino B; Department of Brain and Behavioural Sciences, Medical and Genomic Statistics Unit, University of Pavia, Pavia, Italy., Tan K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Huber H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cantoni V; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy., Bracca V; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Gasparotti R; Neuroradiology Unit, University of Brescia, Brescia, Italy., Premi E; Stroke Unit, ASST Spedali Civili, Brescia, Italy., Logroscino G; Center for Neurodegenerative Diseases and the Aging Brain, Pia Fondazione Cardinale Giovanni Panico, University of Bari-Aldo Moro, Bari, Italy., Benedet AL; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, P.R. China., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Grassi M; Department of Brain and Behavioural Sciences, Medical and Genomic Statistics Unit, University of Pavia, Pavia, Italy., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Banner Sun Health Research Institute, Sun City, Arizona, USA.; Banner Alzheimer's Institute and University of Arizona, Phoenix, Arizona, USA., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.

Journal Article , 2025

TMEM106B C-terminal fragments aggregate and drive neurodegenerative proteinopathy in transgenic Caenorhabditis elegans.

Riordan R; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Saxton A; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA., Han M; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, Washington, USA., McMillan PJ; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA., Kow RL; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Liachko NF; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, Washington, USA., Kraemer BC; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, Washington, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.

Journal Article , 2025

Boostering diagnosis of frontotemporal lobar degeneration with AI-driven neuroimaging - A systematic review and meta-analysis.

Wu Q; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Clinic for Neurology, University of Leipzig Medical Center, Leipzig, Germany. Electronic address: wuqi@cbs.mpg.de., Kiakou D; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Department of Neurology, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Mueller K; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Department of Neurology, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Köhler W; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Clinic for Neurology, University of Leipzig Medical Center, Leipzig, Germany., Schroeter ML; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Clinic for Cognitive Neurology, University of Leipzig Medical Center, Leipzig, Germany. Electronic address: schroet@cbs.mpg.de.

Journal Article; Systematic Review; Meta-Analysis , 2025

Origin and cell type specificity of mitochondrial DNA mutations in C9ORF72 ALS-FTLD human brain organoids.

Nie Y; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Szebényi K; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Wenger LMD; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Lakatos A; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Chinnery PF; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

Journal Article , 2025

The graded multidimensional geometry of phenotypic variation and progression in neurodegenerative syndromes.

Ramanan S; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK., Akarca D; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK., Henderson SK; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK.; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Rouse MA; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK., Allinson K; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK.; Department of Pathology, Cambridge University Hospitals NHS Trust, Cambridge CB2 1QP, UK., Patterson K; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK.; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Rowe JB; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK.; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 0SZ, UK., Lambon Ralph MA; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK.

Journal Article , 2025

Alternative 3' UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD.

Eck RJ; Graduate Program in Neuroscience, University of Washington, Seattle, WA, 98195, USA.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA, 98104, USA., Valdmanis PN; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, 98195, USA., Liachko NF; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA, 98104, USA.; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, 98108, USA., Kraemer BC; Graduate Program in Neuroscience, University of Washington, Seattle, WA, 98195, USA. kraemerb@uw.edu.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA, 98104, USA. kraemerb@uw.edu.; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, 98108, USA. kraemerb@uw.edu.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA. kraemerb@uw.edu.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, 98195, USA. kraemerb@uw.edu.

Journal Article , 2025

Clinical and imaging correlates of hyperorality in syndromes associated with frontotemporal lobar degeneration.

Altomare D; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Bracca V; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Premi E; Stroke Unit, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili, Brescia, Italy., Micheli A; Casa di Cura San Francesco, Istituto Madre Rubatto, Bergamo, Italy., Cotelli MS; Department of Continuity of Care and Frailty, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili, Brescia, Italy., Gasparotti R; Neuroradiology Unit, University of Brescia, Brescia, Italy., Alberici A; Department of Continuity of Care and Frailty, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili, Brescia, Italy., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Department of Continuity of Care and Frailty, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili, Brescia, Italy.

Journal Article , 2024