Search Results - "Hooft van Huijsduijnen, Rob"

The Pandemic Response BoxAccelerating Drug Discovery Efforts after Disease Outbreaks

Samby, Kirandeep^aff1, Besson, Dominique^aff1, Dutta, Anirban^aff2, Patra, Buddhadev^aff2, Doy, Angelique^aff1, Glossop, Paul^aff3, Mills, James^aff3, Whitlock, Gavin^aff3, Hooft van Huijsduijnen, Rob^aff1, Monaco, Alessandra^aff4, Bilbe, Graeme^aff4, Mowbray, Charles^aff4, Perry, Benjamin^aff4, Adam, Anna^aff1, Wells, Timothy N. C.^aff1, Willis, Paul A.^aff1

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Van Voorhis, Wesley C, Adams, John H, Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H, Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T, Avery, Simon V, Avery, Vicky M, Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E, Boyom, Fabrice F, Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R, Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L, Colón-López, Daisy D, Corbett, Yolanda, Crowther, Gregory J, Cowan, Noemi, D'Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L, Du, Alan Y, Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T, Fernández Robledo, José A, Fidock, David A, Florent, Isabelle, Fokou, Patrick VT, Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M, Guha, Rajarshi, Guiguemde, W Armand, Gural, Nil, Guy, R Kiplin, Hansen, Michael AE, Hanson, Kirsten K, Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B, Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A, Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T, Jiang, Rays HY, Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P, Kyle, Dennis E, Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M, Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I, Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis

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The antimalarial pipeline

Hooft van Huijsduijnen, Rob, Wells, Timothy NC

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan

Both Intrinsic Substrate Preference and Network Context Contribute to Substrate Selection of Classical Tyrosine Phosphatases

Palma, Anita, Tinti, Michele, Paoluzi, Serena, Santonico, Elena, Brandt, Bernd Willem, Hooft van Huijsduijnen, Rob, Masch, Antonia, Heringa, Jaap, Schutkowski, Mike, Castagnoli, Luisa, Cesareni, Gianni

Two successful decades of Swiss collaborations to develop new anti-malarials

Hooft van Huijsduijnen, Rob^Aff1, Wells, Timothy^Aff1, Tanner, Marcel^{Aff2, Aff3}, Wittlin, Sergio^{Aff2, Aff3}

A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria

Burrows, Jeremy^Aff1, Slater, Hannah^{Aff2, Aff3}, Macintyre, Fiona, Rees, Sarah, Thomas, Anna, Okumu, Fredros^{Aff5, Aff6, Aff7}, Hooft van Huijsduijnen, Rob, Duparc, Stephan, Wells, Timothy N. C.

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria

Macintyre, Fiona, Ramachandruni, Hanu, Burrows, Jeremy N., Holm, René^{Aff2, Aff3}, Thomas, Anna, Möhrle, Jörg J., Duparc, Stephan, Hooft van Huijsduijnen, Rob, Greenwood, Brian, Gutteridge, Winston E., Wells, Timothy N. C.^Aff1, Kaszubska, Wiweka

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines

Alirol, Emilie, Wi, Teodora E., Bala, Manju, Bazzo, Maria Luiza, Chen, Xiang-Sheng, Deal, Carolyn, Dillon, Jo-Anne R., Kularatne, Ranmini, Heim, Jutta, Hooft van Huijsduijnen, Rob, Hook, Edward W., Lahra, Monica M., Lewis, David A., Ndowa, Francis, Shafer, William M., Tayler, Liz, Workowski, Kimberly, Unemo, Magnus, 1970, Balasegaram, Manica

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Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B

Gomez, Elodie, Vercauteren, Magali, Kurtz, Baptiste, Ouvrard-Pascaud, Antoine, Mulder, Paul, Henry, Jean-Paul, Besnier, Marie, Waget, Aurélie, Hooft Van Huijsduijnen, Rob, Tremblay, Michel L., Burcelin, Remy, Thuillez, Christian, Richard, Vincent

Reassessing therapeutic antibodies for neglected and tropical diseases.

Hooft van Huijsduijnen, Rob¹ (AUTHOR), Kojima, Somei² (AUTHOR), Carter, Dee³ (AUTHOR), Okabe, Hisafumi⁴ (AUTHOR), Sato, Akihide⁴ (AUTHOR), Akahata, Wataru⁵ (AUTHOR), Wells, Timothy N. C.¹ (AUTHOR), Katsuno, Kei^6,7,8 (AUTHOR) kei.katsuno@lshtm.ac.uk

Monitor – Biology

Cheung, Herman H., Kruidering, Marieke, Noble, Christian G, Miller, David J., Barnes, Matt J., Gao, George F., Collin, Mattias, Chen, Shawn, Hooft van Huijsduijnen, Rob

Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Infection Medicine (BMC), Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Infektionsmedicin, Originator

Prospects for Inhibitors of Protein Tyrosine Phosphatase 1B as Antidiabetic Drugs

Hooft van Huijsduijnen, Rob, Sauer, Wolfgang H. B., Bombrun, Agnes, Swinnen, Dominique

Protein tyrosine phosphatases in glioma biology

Navis, Anna C., van den Eijnden, Monique, Schepens, Jan T. G., Hooft van Huijsduijnen, Rob, Wesseling, Pieter, Hendriks, Wiljan J. A. J.

Decompartmentalizing target validation—thinking outside the pipeline boxes

Hooft van Huijsduijnen, Rob, Rommel, Christian

Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

Grundner, Christoph, Perrin, Dominique, Hooft van Huijsduijnen, Rob, Swinnen, Dominique, Gonzalez, Jérome, Gee, Christine L., Wells, Timothy N., Alber, Tom

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPρ/PTPRT)

Besco, Julie A., Hooft van Huijsduijnen, Rob, Frostholm, Adrienne, Rotter, Andrej

Applying the SPOT peptide synthesis procedure to the study of protein tyrosine phosphatase substrate specificity: probing for the heavenly match in vitro

Espanel, Xavier ^*, Hooft van Huijsduijnen, Rob ^*

Biology

Haefner, Burkhard, Golsteyn, Roy M, Seringhaus, Michael R, Hooft van Huijsduijnen, Rob, Hooft van Huijsduijnen, Olfa, Ilag, Leodevico L, Gaither, Alex, Heath, Victoria, Sarker, Dipak K

The Pandemic Response Box Accelerating Drug Discovery Efforts after Disease Outbreaks.

Samby, Kirandeep¹ sambyk-consultants@mmv.org, Besson, Dominique¹, Dutta, Anirban², Patra, Buddhadev², Angelique Doy¹, Glossop, Paul³, Mills, James³, Whitlock, Gavin³, Hooft van Huijsduijnen, Rob¹, Monaco, Alessandra⁴, Bilbe, Graeme⁴, Mowbray, Charles⁴, Perry, Benjamin⁴, Adam, Anna¹, Wells, Timothy N. C.¹, Willis, Paul A.¹ willisp@mmv.org