Search Results - "Ing-Jun Chen"

Restoration of uridine 5′-triphosphate-suppressed delayed rectifying K+ currents by an NO activator KMUP-1 involves RhoA/Rho kinase signaling in pulmonary artery smooth muscle cells

Zen-Kong Dai, Chang-Ling Kao, Su-Ling Hsieh, Ing-Jun Chen, Bin-Nan Wu

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Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca2+ sensitization

Chung-Pin Liu, Jwu-Lai Yeh, Shu-Fen Liou, Bin-Nan Wu, Ing-Jun Chen

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Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss[S]

Kung-Kai Kuo, Bin-Nan Wu, Chung-Pin Liu, Tzu-Yang Yang, Li-Pin Kao, Jiunn-Ren Wu, Wen-Ter Lai, Ing-Jun Chen

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KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways

Shu-Fen Liou, Jong-Hau Hsu, You-Ting Chen, Ing-Jun Chen, Jwu-Lai Yeh

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Buffered l-ascorbic acid, alone or bound to KMUP-1 or sildenafil, reduces vascular endothelium growth factor and restores endothelium nitric oxide synthase in hypoxic pulmonary artery

Jiunn-Ren Wu, Li-Pin Kao, Bin-Nan Wu, Zen-Kong Dai, Yi-Ya Wang, Chee-Yin Chai, Ing-Jun Chen

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Endothelial nitric oxide synthase-enhancing G-protein coupled receptor antagonist inhibits pulmonary artery hypertension by endothelin-1-dependent and endothelin-1-independent pathways in a monocrotaline model

Chung-Pin Liu, Zen-Kong Dai, Chein-Heng Huang, Jwu-Lai Yeh, Bin-Nan Wu, Jiunn-Ren Wu, Ing-Jun Chen

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Eugenosedin-A ameliorates hyperlipidemia-induced vascular endothelial dysfunction via inhibition of α1-adrenoceptor/5-HT activity and NADPH oxidase expression

Kuo-Ping Shen, Hui-Li Lin, Wen-Tsan Chang, Jou-Chun Lin, Li-Mei An, Ing-Jun Chen, Bin-Nan Wu

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KMUP-1 inhibits hypertension-induced left ventricular hypertrophy through regulation of nitric oxide synthases, ERK1/2, and calcineurin

Jwu-Lai Yeh, Chung-Pin Liu, Jong-Hau Hsu, Ching-Jiunn Tseng, Ping-Ju Wu, Yi-Ya Wang, Jiunn-Ren Wu, Ing-Jun Chen

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KMUP-1 inhibits L-type Ca2+ channels involved the protein kinase C in rat basilar artery myocytes

Jun-Yih Chen, Min-Chi Jiang, Li-Wen Chu, Su-Ling Hsieh, Ing-Jun Chen, Bin-Nan Wu

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ANTI-PROLIFERATIVE EFFECTIVENESS OF LERCANIDIPINE AND ITS MECHANISM OF ACTION (EXPERIMENTAL STUDY)

Jiunn-Ren Wu, Shu-Fen Liou, Shin-Wha Lin, Chee-Yin Chai, Zen-Kong Dai, Jyh-Chong Liang, Ing-Jun Chen, Jwu-Lai Yeh

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KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPARγ and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes

Chung-Pin Liu, Pei-Chun Chau, Chain-Ting Chang, Li-Mei An, Jwu-Lai Yeh, Ing-Jun Chen, Bin-Nan Wu

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KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways.

Shu-Fen Liou, Jong-Hau Hsu, I-Ling Lin, Mei-Ling Ho, Pei-Chuan Hsu, Li-Wen Chen, Ing-Jun Chen, Jwu-Lai Yeh

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Theophylline-Based KMUP-1 Improves Steatohepatitis via MMP-9/IL-10 and Lipolysis via HSL/p-HSL in Obese Mice.

Bin-Nan Wu, Kung-Kai Kuo, Yu-Hsun Chen, Chain-Ting Chang, Hung-Tu Huang, Chee-Yin Chai, Zen-Kong Dai, Ing-Jun Chen

Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells.

I-Shan Chen, Zen-Kong Dai, Welsh, Donald G., Ing-Jun Chen, Bin-Nan Wu

Roles of the Genetic Polymorphisms of Alcohol-Metabolizing Enzymes on the Immunology in High-Risk Drinkers.

Yang-Ming Tseng, Shih-Meng Tsai, Sheng-Yi Chen, Chun-Chin Lin, Yi-Ru Jin, Wei-Hao Yeh, Yi-Ru Wu, Ing-Jun Chen, Jang-Hwa Lee, Li-Yu Tsai

Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet.

Kuo-Ping Shen, Hui-Li Lin, Su-Ling Hsieh, Aij-Lie Kwan, Ing-Jun Chen, Bin-Nan Wu

Isoeugenodilol inhibits smooth muscle cell proliferation and neointimal thickening after balloon injury via inactivation of ERK1/2 pathway.

Jwu-Lai Yeh, Shu-Fen Liou, Yu-Pay Chang, Shin-Wha Lin, Ts'an-Shiun Liu, Bin-Nan Wu, Ing-Jun Chen, Jiunn-Ren Wu

Eugenosedin-A amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2.

Kuo-Ping Shen, Shu-Fen Liou, Su-Ling Hsieh, Ing-Jun Chen, Bin-Nan Wu

KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases.

Bin-Nan Wu, Hsiao-Fang Tu, Welsh, Donald G., Ing-Jun Chen

KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K⁺ channels.

Wu, Bin-Nan, Lin, Rong-Jyh, Yi-Ching Lo, Kuo-Pyng Shen, Chao-Chuan Wang, Young-Tso Lin, Ing-Jun Chen