Search Results - "Jörg Lippert"

Harnessing Open‐Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference

André Dallmann, Denise Feick, Pavel Balazki, Salih Benamara, Rolf Burghaus, Marylore Chenel, Siak‐Leng Choi, Henrik Cordes, Mariana Guimarães, Abdullah Hamadeh, Ibrahim Ince, Kathleen M. Job, Tobias Kanacher, Andreas Kovar, Lars Kuepfer, Jörg Lippert, Julia Macente, Nina Nauwelaerts, Christoph Niederalt, Sheila Peters, Susana Proença, Masanobu Sato, Stephan Schaller, Jan Frederik Schlender, Annika Schneider, Erik Sjögren, Juri Solodenko, Alexander Staab, Paul Vrenken, Thomas Wendl, Wilhelmus E. A. deWitte, Donato Teutonico

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Data-driven identification of heart failure disease states and progression pathways using electronic health records

Tasha Nagamine, Brian Gillette, John Kahoun, Rolf Burghaus, Jörg Lippert, Mayur Saxena

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Model‐informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease

Stefan Willmann, Ibrahim Ince, Maurice Ahsman, Katrin Coboeken, Yang Zhang, Kirstin Thelen, Dagmar Kubitza, Peter Zannikos, Wangda Zhou, Liza Miriam Pina, Teun Post, Jörg Lippert

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CKD subpopulations defined by risk‐factors: A longitudinal analysis of electronic health records

Rajagopalan Ramaswamy, Soon Nan Wee, Kavya George, Abhijit Ghosh, Joydeep Sarkar, Rolf Burghaus, Jörg Lippert

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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically‐based pharmacokinetic predictions

Stefan Willmann, Katrin Coboeken, Yang Zhang, Hannah Mayer, Ibrahim Ince, Emir Mesic, Kirstin Thelen, Dagmar Kubitza, Anthonie W. A. Lensing, Haitao Yang, Peijuan Zhu, Wolfgang Mück, Henk‐Jan Drenth, Jörg Lippert

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Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment

Rebekka Fendt, Ute Hofmann, Annika R. P. Schneider, Elke Schaeffeler, Rolf Burghaus, Ali Yilmaz, Lars Mathias Blank, Reinhold Kerb, Jörg Lippert, Jan‐Frederik Schlender, Matthias Schwab, Lars Kuepfer

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A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4–mediated drug–drug interactions

Sebastian Frechen, Juri Solodenko, Thomas Wendl, André Dallmann, Ibrahim Ince, Thorsten Lehr, Jörg Lippert, Rolf Burghaus

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Multiscale classification of heart failure phenotypes by unsupervised clustering of unstructured electronic medical record data

Tasha Nagamine, Brian Gillette, Alexey Pakhomov, John Kahoun, Hannah Mayer, Rolf Burghaus, Jörg Lippert, Mayur Saxena

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Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

Jörg Lippert, Rolf Burghaus, Andrea Edginton, Sebastian Frechen, Mats Karlsson, Andreas Kovar, Thorsten Lehr, Peter Milligan, Valerie Nock, Sergej Ramusovic, Matthew Riggs, Stephan Schaller, Jan Schlender, Stephan Schmidt, Michaël Sevestre, Erik Sjögren, Juri Solodenko, Alexander Staab, Donato Teutonico

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Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin

Stefan Willmann, Matthias Frei, Gabriele Sutter, Katrin Coboeken, Thomas Wendl, Thomas Eissing, Jörg Lippert, Heino Stass

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Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study

Stefan Willmann, Kirstin Thelen, Dagmar Kubitza, Anthonie W. A. Lensing, Matthias Frede, Katrin Coboeken, Jan Stampfuss, Rolf Burghaus, Wolfgang Mück, Jörg Lippert

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Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach.

Priyata Kalra, Julian Brandl, Thomas Gaub, Christoph Niederalt, Jörg Lippert, Sven Sahle, Lars Küpfer, Ursula Kummer

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Integrating cellular metabolism into a multiscale whole-body model.

Markus Krauss, Stephan Schaller, Steffen Borchers, Rolf Findeisen, Jörg Lippert, Lars Kuepfer

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