Sökresultat - "Janet Piñero"

A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug‐induced toxicity

Louis Gall, Ferran Jardi, Lieve Lammens, Janet Piñero, Terezinha M. Souza, Daniela Rodrigues, Danyel G. J. Jennen, Theo M. deKok, Luke Coyle, Seung‐Wook Chung, Sofia Ferreira, Heeseung Jo, Kylie A. Beattie, Colette Kelly, Carrie A. Duckworth, D. Mark Pritchard, Carmen Pin

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Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches

Anna Niarakis, Marek Ostaszewski, Alexander Mazein, Inna Kuperstein, Martina Kutmon, Marc E. Gillespie, Akira Funahashi, Marcio Luis Acencio, Ahmed Hemedan, Michael Aichem, Karsten Klein, Tobias Czauderna, Felicia Burtscher, Takahiro G. Yamada, Yusuke Hiki, Noriko F. Hiroi, Finterly Hu, Nhung Pham, Friederike Ehrhart, Egon L. Willighagen, Alberto Valdeolivas, Aurelien Dugourd, Francesco Messina, Marina Esteban-Medina, Maria Peña-Chilet, Kinza Rian, Sylvain Soliman, Sara Sadat Aghamiri, Bhanwar Lal Puniya, Aurélien Naldi, Tomáš Helikar, Vidisha Singh, Marco Fariñas Fernández, Viviam Bermudez, Eirini Tsirvouli, Arnau Montagud, Vincent Noël, Miguel Ponce-de-Leon, Dieter Maier, Angela Bauch, Benjamin M. Gyori, John A. Bachman, Augustin Luna, Janet Piñero, Laura I. Furlong, Irina Balaur, Adrien Rougny, Yohan Jarosz, Rupert W. Overall, Robert Phair, Livia Perfetto, Lisa Matthews, Devasahayam Arokia Balaya Rex, Marija Orlic-Milacic, Luis Cristobal Monraz Gomez, Bertrand De Meulder, Jean Marie Ravel, Bijay Jassal, Venkata Satagopam, Guanming Wu, Martin Golebiewski, Piotr Gawron, Laurence Calzone, Jacques S. Beckmann, Chris T. Evelo, Peter D’Eustachio, Falk Schreiber, Julio Saez-Rodriguez, Joaquin Dopazo, Martin Kuiper, Alfonso Valencia, Olaf Wolkenhauer, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID-19 Disease Map Community

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Genomic and proteomic biomarker landscape in clinical trials

Janet Piñero, Pablo S. Rodriguez Fraga, Jordi Valls-Margarit, Francesco Ronzano, Pablo Accuosto, Ricard Lambea Jane, Ferran Sanz, Laura I. Furlong

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Visualization of automatically combined disease maps and pathway diagrams for rare diseases

Piotr Gawron, David Hoksza, Janet Piñero, Maria Peña-Chilet, Marina Esteban-Medina, Jose Luis Fernandez-Rueda, Vincenza Colonna, Ewa Smula, Laurent Heirendt, François Ancien, Valentin Groues, Venkata P. Satagopam, Reinhard Schneider, Joaquin Dopazo, Laura I. Furlong, Marek Ostaszewski

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Assessing network-based methods in the context of system toxicology

Jordi Valls-Margarit, Janet Piñero, Barbara Füzi, Natacha Cerisier, Olivier Taboureau, Laura I. Furlong

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Identifying multiscale translational safety biomarkers using a network-based systems approach

Giulia Callegaro, Johannes P. Schimming, Janet Piñero González, Steven J. Kunnen, Lukas Wijaya, Panuwat Trairatphisan, Linda van den Berk, Kim Beetsma, Laura I. Furlong, Jeffrey J. Sutherland, Jennifer Mollon, James L. Stevens, Bob van de Water

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Benchmarking post-GWAS analysis tools in major depression: Challenges and implications

Judith Pérez-Granado, Janet Piñero, Laura I. Furlong

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Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice

Ana Martín-Sánchez, Janet Piñero, Lara Nonell, Magdalena Arnal, Elena M. Ribe, Alejo Nevado-Holgado, Simon Lovestone, Ferran Sanz, Laura I. Furlong, Olga Valverde

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The DisGeNET cytoscape app: Exploring and visualizing disease genomics data

Janet Piñero, Josep Saüch, Ferran Sanz, Laura I. Furlong

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An ensemble learning approach for modeling the systems biology of drug-induced injury

Joaquim Aguirre-Plans, Janet Piñero, Terezinha Souza, Giulia Callegaro, Steven J. Kunnen, Ferran Sanz, Narcis Fernandez-Fuentes, Laura I. Furlong, Emre Guney, Baldo Oliva

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SARS‐CoV‐2 sculpts the immune system to induce sustained virus‐specific naïve‐like and memory B‐cell responses

Leire de Campos‐Mata, Sonia Tejedor Vaquero, Roser Tachó‐Piñot, Janet Piñero, Emilie K Grasset, Itziar Arrieta Aldea, Natalia Rodrigo Melero, Carlo Carolis, Juan P Horcajada, Andrea Cerutti, Judit Villar‐García, Giuliana Magri

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The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research [version 1; peer review: 2 approved]

David Salgado, Irina M. Armean, Michael Baudis, Sergi Beltran, Salvador Capella-Gutierrez, Denise Carvalho-Silva, Victoria Dominguez Del Angel, Joaquin Dopazo, Laura I. Furlong, Bo Gao, Leyla Garcia, Dietlind Gerloff, Ivo Gut, Attila Gyenesei, Nina Habermann, John M. Hancock, Marc Hanauer, Eivind Hovig, Lennart F. Johansson, Thomas Keane, Jan Korbel, Katharina B. Lauer, Steve Laurie, Brane Leskošek, David Lloyd, Tomas Marques-Bonet, Hailiang Mei, Katalin Monostory, Janet Piñero, Krzysztof Poterlowicz, Ana Rath, Pubudu Samarakoon, Ferran Sanz, Gary Saunders, Daoud Sie, Morris A. Swertz, Kirill Tsukanov, Alfonso Valencia, Marko Vidak, Cristina Yenyxe González, Bauke Ylstra, Christophe Béroud

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Genetic and functional characterization of disease associations explains comorbidity

Carlota Rubio-Perez, Emre Guney, Daniel Aguilar, Janet Piñero, Javier Garcia-Garcia, Barbara Iadarola, Ferran Sanz, Narcís Fernandez-Fuentes, Laura I. Furlong, Baldo Oliva

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The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

François Pognan, Thomas Steger-Hartmann, Carlos Díaz, Niklas Blomberg, Frank Bringezu, Katharine Briggs, Giulia Callegaro, Salvador Capella-Gutierrez, Emilio Centeno, Javier Corvi, Philip Drew, William C. Drewe, José M. Fernández, Laura I. Furlong, Emre Guney, Jan A. Kors, Miguel Angel Mayer, Manuel Pastor, Janet Piñero, Juan Manuel Ramírez-Anguita, Francesco Ronzano, Philip Rowell, Josep Saüch-Pitarch, Alfonso Valencia, Bob van de Water, Johan van der Lei, Erik van Mulligen, Ferran Sanz

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Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury

Terezinha Souza, Panuwat Trairatphisan, Janet Piñero, Laura I. Furlong, Julio Saez-Rodriguez, Jos Kleinjans, Danyel Jennen

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Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response

Janet Piñero, Abel Gonzalez-Perez, Emre Guney, Joaquim Aguirre-Plans, Ferran Sanz, Baldo Oliva, Laura I. Furlong

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Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology

Joaquim Aguirre-Plans, Janet Piñero, Jörg Menche, Ferran Sanz, Laura I. Furlong, Harald H. H. W. Schmidt, Baldo Oliva, Emre Guney

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Mining the modular structure of protein interaction networks.

Ariel José Berenstein, Janet Piñero, Laura Inés Furlong, Ariel Chernomoretz

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Correction: Automatic Filtering and Substantiation of Drug Safety Signals.

Anna Bauer-Mehren, Erik M. van Mullingen, Paul Avillach, María del Carmen Carrascosa, Ricard Garcia-Serna, Janet Piñero, Bharat Singh, Pedro Lopes, José L. Oliveira, Gayo Diallo, Ernst Ahlberg Helgee, Scott Boyer, Jordi Mestres, Ferran Sanz, Jan A. Kors, Laura I. Furlong

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Automatic filtering and substantiation of drug safety signals.

Anna Bauer-Mehren, Erik M van Mullingen, Paul Avillach, María Del Carmen Carrascosa, Ricard Garcia-Serna, Janet Piñero, Bharat Singh, Pedro Lopes, José L Oliveira, Gayo Diallo, Ernst Ahlberg Helgee, Scott Boyer, Jordi Mestres, Ferran Sanz, Jan A Kors, Laura I Furlong

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