Sökresultat - "Jesper Wengel"

Anti-gene oligonucleotides targeting Friedreich’s ataxia expanded GAA⋅TTC repeats increase Frataxin expression

Negin Mozafari, Salomé Milagres, Tea Umek, Cristina S.J. Rocha, Claudia M. Vargiu, Fiona Freyberger, Osama Saher, Marek Napierala, Jill S. Napierala, Pontus Blomberg, Per T. Jørgensen, Tanel Punga, C. I. Edvard Smith, Jesper Wengel, Rula Zain

electronic resource

Visa; Visa

Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers

Jörg Duschmalé, Adrian Schäublin, Erik Funder, Steffen Schmidt, Łukasz J. Kiełpiński, Helle Nymark, Klaus Jensen, Troels Koch, Martina Duschmalé, Erich Koller, Marianne Ravn Møller, Simone Schadt, Christophe Husser, Andreas Brink, Sabine Sewing, Tanja Minz, Jesper Wengel, Konrad Bleicher, Meiling Li

electronic resource

Visa; Visa

Chirality transmission in macromolecular domains

Shankar Pandey, Shankar Mandal, Mathias Bogetoft Danielsen, Asha Brown, Changpeng Hu, Niels Johan Christensen, Alina Vitaliyivna Kulakova, Shixi Song, Tom Brown, Knud J. Jensen, Jesper Wengel, Chenguang Lou, Hanbin Mao

electronic resource

Visa

Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides

Mathias B. Danielsen, Jesper Wengel

electronic resource

Visa

Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds

Marjan Omer, Veronica Liv Andersen, Jesper Sejrup Nielsen, Jesper Wengel, Jørgen Kjems

electronic resource

Visa; Visa

Spectral imaging and nucleic acid mimics fluorescence in situ hybridization (SI-NAM-FISH) for multiplex detection of clinical pathogens

Andreia S. Azevedo, Ricardo M. Fernandes, Ana R. Faria, Oscar F. Silvestre, Jana B. Nieder, Chenguang Lou, Jesper Wengel, Carina Almeida, Nuno F. Azevedo

electronic resource

Visa; Visa

Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation

Anet Laanesoo, Egon Urgard, Kapilraj Periyasamy, Martti Laan, Yury A. Bochkov, Alar Aab, Nathaniel Magilnick, Margus Pooga, James E. Gern, Sebastian L. Johnston, Jonathan M. Coquet, Mark P. Boldin, Jesper Wengel, Alan Altraja, Grazyna Bochenek, Bogdan Jakiela, Ana Rebane

electronic resource

Visa

Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury

Pedro M.D. Moreno, Ana R. Ferreira, Daniela Salvador, Maria T. Rodrigues, Marília Torrado, Eva D. Carvalho, Ulf Tedebark, Mónica M. Sousa, Isabel F. Amaral, Jesper Wengel, Ana P. Pêgo

electronic resource

Visa; Visa

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

Weronika Kotkowiak, Jolanta Lisowiec-Wachnicka, Jakub Grynda, Ryszard Kierzek, Jesper Wengel, Anna Pasternak

electronic resource

Visa; Visa

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications

Matthias Kuhlmann, Jonas B.R. Hamming, Anders Voldum, Georgia Tsakiridou, Maja T. Larsen, Julie S. Schmøkel, Emil Sohn, Konrad Bienk, David Schaffert, Esben S. Sørensen, Jesper Wengel, Daniel M. Dupont, Kenneth A. Howard

electronic resource

Visa; Visa

Polyamine–Oligonucleotide Conjugates: 2′-OMe-Triazole-Linked 1,4,7,10-Tetraazacyclododecane and Intercalating Dyes and Their Effect on the Thermal Stability of DNA Duplexes

Mateusz D. Tomczyk, Mariusz Zalewski, Per T. Jørgensen, Jesper Wengel, Krzysztof Walczak

electronic resource

Visa; Visa

Intramuscular Evaluation of Chimeric Locked Nucleic Acid/2′OMethyl-Modified Antisense Oligonucleotides for Targeted Exon 23 Skipping in Mdx Mice

Michaella Georgiadou, Melina Christou, Kleitos Sokratous, Jesper Wengel, Kyriaki Michailidou, Kyriacos Kyriacou, Andrie Koutsoulidou, Nikolaos P. Mastroyiannopoulos, Leonidas A. Phylactou

electronic resource

Visa; Visa

Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies

Yossa Dwi Hartono, Y. Vladimir Pabon-Martinez, Arzu Uyar, Jesper Wengel, Karin E. Lundin, Rula Zain, C. I. Edvard Smith, Lennart Nilsson, Alessandra Villa

electronic resource

Visa

Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

Chenguang Lou, Manuel C. Martos-Maldonado, Charlotte S. Madsen, Rasmus P. Thomsen, Søren Roi Midtgaard, Niels Johan Christensen, Jørgen Kjems, Peter W. Thulstrup, Jesper Wengel, Knud J. Jensen

electronic resource

Visa

Can Vitamin B12 Assist the Internalization of Antisense LNA Oligonucleotides into Bacteria?

Sara Pereira, Ruwei Yao, Mariana Gomes, Per Trolle Jørgensen, Jesper Wengel, Nuno Filipe Azevedo, Rita Sobral Santos

electronic resource

Visa; Visa

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study.

You Xu, Olof Gissberg, Y Vladimir Pabon-Martinez, Jesper Wengel, Karin E Lundin, C I Edvard Smith, Rula Zain, Lennart Nilsson, Alessandra Villa

electronic resource

Visa

Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides

Yogesh Yadav, Deepti Sharma, Kumar Kaushik, Vineet Kumar, Amitabh Jha, Ashok K. Prasad, Christophe Len, Sanjay V. Malhotra, Jesper Wengel, Virinder S. Parmar

electronic resource

Visa; Visa

Amplification and Re-Generation of LNA-Modified Libraries

Jesper Wengel, Birte Vester, Lykke H. Hansen, Rakesh N. Veedu, Holger Doessing

electronic resource

Visa; Visa

Oligonucleotide Binding to Non-B-DNA in MYC

Tea Umek, Karin Sollander, Helen Bergquist, Jesper Wengel, Karin E. Lundin, C.I. Edvard Smith, Rula Zain

electronic resource

Visa; Visa

Fluorescence In Vivo Hybridization (FIVH) for Detection of Helicobacter pylori Infection in a C57BL/6 Mouse Model.

Sílvia Fontenete, Marina Leite, Davie Cappoen, Rita Santos, Chris Van Ginneken, Céu Figueiredo, Jesper Wengel, Paul Cos, Nuno Filipe Azevedo

electronic resource

Visa; Visa