Search Results - "Klumpp-Thomas, Carleen"

Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules

Ryu, Seungmi^Aff4, Chu, Pei-Hsuan^Aff4, Malley, Claire^Aff4, Braisted, John^Aff4, Ormanoglu, Pinar^Aff4, Huang, Ruili^Aff4, Itkin, Misha^Aff4, Itkin, Zina^Aff4, Shinn, Paul^Aff4, Klumpp-Thomas, Carleen^Aff4, Michael, Sam^Aff4, Tristan, Carlos A.^Aff4, Simeonov, Anton^Aff4, Singeç, Ilyas^Aff4

Nagy, Andras^Aff2, Turksen, Kursad^Aff3, Walker, John M.^Aff1

High-Throughput Screening for Drug Combinations

Shinn, Paul^Aff4, Chen, Lu^Aff4, Ferrer, Marc^Aff4, Itkin, Zina^Aff4, Klumpp-Thomas, Carleen^Aff4, McKnight, Crystal^Aff4, Michael, Sam^Aff4, Mierzwa, Tim^Aff4, Thomas, Craig^Aff4, Wilson, Kelli^Aff4, Guha, Rajarshi^Aff5

Larson, Richard S.^Aff2, Oprea, Tudor I.^Aff3, Walker, John M.^Aff1

Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

Shrimp, Jonathan H., Janiszewski, John, Chen, Catherine Z., Xu, Miao, Wilson, Kelli M., Kales, Stephen C., Sanderson, Philip E., Shinn, Paul, Schneider, Rick, Itkin, Zina, Guo, Hui, Shen, Min, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei, Simeonov, Anton, Hall, Matthew D.

Discovery and Optimization of 2H‑1λ2‑Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer

Rohde, Jason M.^aff1, Karavadhi, Surendra^aff1, Pragani, Rajan^aff1, Liu, Li^aff1, Fang, Yuhong^aff1, Zhang, Weihe^aff2, McIver, Andrew^aff2, Zheng, Hongchao^aff2, Liu, Qingyang^aff2, Davis, Mindy I.^aff1, Urban, Daniel J.^aff1, Lee, Tobie D.^aff1, Cheff, Dorian M.^aff1, Hollingshead, Melinda^aff3, Henderson, Mark J.^aff1, Martinez, Natalia J.^aff1, Brimacombe, Kyle R.^aff1, Yasgar, Adam^aff1, Zhao, Wei^aff1, Klumpp-Thomas, Carleen^aff1, Michael, Sam^aff1, Covey, Joseph^aff4, Moore, William J.^aff5, Stott, Gordon M.^aff5, Li, Zhuyin^aff1, Simeonov, Anton^aff1, Jadhav, Ajit^aff1, Frye, Stephen^aff2, Hall, Matthew D.^aff1, Shen, Min^aff1, Wang, Xiaodong^aff2, Patnaik, Samarjit^aff1, Boxer, Matthew B.^aff1

The SARS-CoV‑2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

Gorshkov, Kirill^aff1, Chen, Catherine Z.^aff1, Bostwick, Robert^aff2, Rasmussen, Lynn^aff2, Tran, Bruce Nguyen^aff1, Cheng, Yu-Shan^aff1, Xu, Miao^aff1, Pradhan, Manisha^aff1, Henderson, Mark^aff1, Zhu, Wei^aff1, Oh, Eunkeu^aff3, Susumu, Kimihiro^{aff3, aff4}, Wolak, Mason^aff3, Shamim, Khalida^aff1, Huang, Wenwei^aff1, Hu, Xin^aff1, Shen, Min^aff1, Klumpp-Thomas, Carleen^aff1, Itkin, Zina^aff1, Shinn, Paul^aff1, Carlos de la Torre, Juan^aff5, Simeonov, Anton^aff1, Michael, Sam G.^aff1, Hall, Matthew D.^aff1, Lo, Donald C.^aff1, Zheng, Wei^aff1

Identifying SARS-CoV‑2 Entry Inhibitors through Drug Repurposing Screens of SARS‑S and MERS‑S Pseudotyped Particles

Chen, Catherine Z.^aff1, Xu, Miao^aff1, Pradhan, Manisha^aff1, Gorshkov, Kirill^aff1, Petersen, Jennifer D.^aff2, Straus, Marco R.^aff3, Zhu, Wei^aff1, Shinn, Paul^aff1, Guo, Hui^aff1, Shen, Min^aff1, Klumpp-Thomas, Carleen^aff1, Michael, Samuel G.^aff1, Zimmerberg, Joshua^aff2, Zheng, Wei^aff1, Whittaker, Gary R.^aff3

Identification of SARS-CoV‑2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

Zhu, Wei, Xu, Miao, Chen, Catherine Z., Guo, Hui, Shen, Min, Hu, Xin, Shinn, Paul, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei

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Large-scale human myeloma cell line small molecule compound screen dataset

Hughitt, V. Keith, Simmons, John K.^{Aff1, Aff2}, Gorjifard, Sayeh^{Aff1, Aff3}, Michalowski, Aleksandra, Wilson, Kelli, Zhang, Xiaohu, Shinn, Paul, Klumpp-Thomas, Carleen, McKnight, Crystal, Itkin, Zina, Chen, Lu, Michael, Sam, Keats, Jonathan, Thomas, Craig, Mock, Beverly A.^{Aff1, IDs41597025049898_cor1}

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Kearney, Sara E.^aff1, Zahoránszky-Kőhalmi, Gergely^aff1, Brimacombe, Kyle R.^aff1, Henderson, Mark J.^aff1, Lynch, Caitlin^aff1, Zhao, Tongan^aff1, Wan, Kanny K.^{aff1, aff2}, Itkin, Zina^aff1, Dillon, Christopher^aff1, Shen, Min^aff1, Cheff, Dorian M.^aff1, Lee, Tobie D.^aff1, Bougie, Danielle^aff1, Cheng, Ken^aff1, Coussens, Nathan P.^aff1, Dorjsuren, Dorjbal^aff1, Eastman, Richard T.^aff1, Huang, Ruili^aff1, Iannotti, Michael J.^aff1, Karavadhi, Surendra^aff1, Klumpp-Thomas, Carleen^aff1, Roth, Jacob S.^aff1, Sakamuru, Srilatha^aff1, Sun, Wei^aff1, Titus, Steven A.^aff1, Yasgar, Adam^aff1, Zhang, Ya-Qin^aff1, Zhao, Jinghua^aff1, Andrade, Rodrigo B.^aff3, Brown, M. Kevin^aff4, Burns, Noah Z.^aff5, Cha, Jin K.^aff6, Mevers, Emily E.^aff7, Clardy, Jon^aff7, Clement, Jason A.^aff8, Crooks, Peter A.^aff9, Cuny, Gregory D.^aff10, Ganor, Jake^aff11, Moreno, Jesus^aff12, Morrill, Lucas A.^aff12, Picazo, Elias^aff12, Susick, Robert B.^aff12, Garg, Neil K.^aff12, Goess, Brian C.^aff13, Grossman, Robert B.^aff14, Hughes, Chambers C.^aff15, Johnston, Jeffrey N.^aff16, Joullie, Madeleine M.^aff17, Kinghorn, A. Douglas^aff18, Kingston, David G.I.^aff19, Krische, Michael J.^aff20, Kwon, Ohyun^aff12, Maimone, Thomas J.^aff21, Majumdar, Susruta^{aff22, aff23}, Maloney, Katherine N.^aff24, Mohamed, Enas^aff25, Murphy, Brian T.^aff26, Nagorny, Pavel^aff27, Olson, David E.^{aff28, aff29, aff30}, Overman, Larry E.^aff31, Brown, Lauren E.^aff32, Snyder, John K.^aff32, Porco, John A., Jr.^aff32, Rivas, Fatima^aff33, Ross, Samir A.^aff25, Sarpong, Richmond^aff34, Sharma, Indrajeet^aff35, Shaw, Jared T.^aff28, Xu, Zhengren^aff36, Shen, Ben^aff36, Shi, Wei^aff37, Stephenson, Corey R.J.^aff27, Verano, Alyssa L.^aff38, Tan, Derek S.^{aff38, aff39}, Tang, Yi^aff12, Taylor, Richard E.^aff40, Thomson, Regan J.^aff41, Vosburg, David A.^aff2, Wu, Jimmy^aff42, Wuest, William M.^{aff43, aff44}, Zakarian, Armen^aff45, Zhang, Yufeng^aff46, Ren, Tianjing^aff46, Zuo, Zhong^aff46, Inglese, James^aff1, Michael, Sam^aff1, Simeonov, Anton^aff1, Zheng, Wei^aff1, Shinn, Paul^aff1, Jadhav, Ajit^aff1, Boxer, Matthew B.^aff1, Hall, Matthew D.^aff1, Xia, Menghang^aff1, Guha, Rajarshi^aff1, Rohde, Jason M.^aff1

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Peat, Tyler J., Gaikwad, Snehal M., Dubois, Wendy, Gyabaah-Kessie, Nana, Zhang, Shuling, Gorjifard, Sayeh, Phyo, Zaw, Andres, Megan, Hughitt, V. Keith, Simpson, R. Mark, Miller, Margaret A., Girvin, Andrew T., Taylor, Andrew, Williams, Daniel, D'Antonio, Nelson, Zhang, Yong, Rajagopalan, Adhithi, Flietner, Evan, Wilson, Kelli, Zhang, Xiaohu, Shinn, Paul, Klumpp-Thomas, Carleen, McKnight, Crystal, Itkin, Zina, Chen, Lu, Kazandijian, Dickran, Zhang, Jing, Michalowski, Aleksandra M., Simmons, John K., Keats, Jonathan, Thomas, Craig J., Mock, Beverly A.

Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4

Cheff, Dorian M., Cheng, Qing, Guo, Hui, Travers, Jameson, Klumpp-Thomas, Carleen, Shen, Min, Arnér, Elias S.J., Hall, Matthew D.

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High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

Lang, Martin^{Aff1, Aff2}, Schmidt, Laura S.^{Aff1, Aff3}, Wilson, Kelli M., Ricketts, Christopher J., Sourbier, Carole, Vocke, Cathy D., Wei, Darmood, Crooks, Daniel R., Yang, Youfeng, Gibbs, Benjamin K., Zhang, Xiaohu, Klumpp-Thomas, Carleen, Chen, Lu, Guha, Rajarshi, Ferrer, Marc, McKnight, Crystal, Itkin, Zina, Wangsa, Darawalee, Wangsa, Danny, James, Amy, Difilippantonio, Simone, Karim, Baktir, Morís, Francisco, Ried, Thomas, Merino, Maria J., Srinivasan, Ramaprasad, Thomas, Craig J., Linehan, W. Marston^{Aff1, IDs13046023026674_cor28}

Preclinical validation of a novel therapeutic strategy for choroid plexus carcinoma

Martin, Brice, Garman, Tyler, Laramee, Madeline, Wang, Amy, Zhang, Xiaohu, Beck, Erin, Wilson, Kelli, Klumpp-Thomas, Carleen, McKnight, Crystal, Xu, Xin, Hagen, Natalie, Holland, David, Dahmane, Nadia, Thomas, Craig J., Souweidane, Mark

The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity

Tong, Zhi-Bin, Huang, Ruili, Wang, Yuhong, Klumpp-Thomas, Carleen A., Braisted, John C., Itkin, Zina, Shinn, Paul, Xia, Menghang, Simeonov, Anton, Gerhold, David L.

Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

Ooka, Masato, Zhao, Jinghua, Shah, Pranav, Travers, Jameson, Klumpp-Thomas, Carleen, Xu, Xin, Huang, Ruili, Ferguson, Stephen, Witt, Kristine L., Smith-Roe, Stephanie L., Simeonov, Anton, Xia, Menghang^{Aff1, IDs00204022032915_cor12}

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A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Shen, Min, Guo, Hui, Zhu, Wei, Klumpp-Thomas, Carleen, Michael, Sam, Itkin, Misha, Itkin, Zina, Straus, Marco R., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R., Chen, Catherine Z.

Cross-Platform Bayesian Optimization System for Autonomous Biological Assay Development

Elder, Sam ^*, Klumpp-Thomas, Carleen ^*, Yasgar, Adam, Travers, Jameson, Frebert, Shayne, Wilson, Kelli M., Zakharov, Alexey V., Dahlin, Jayme L., Kreisbeck, Christoph, Sheberla, Dennis, Sittampalam, Gurusingham S., Godfrey, Alexander G., Simeonov, Anton, Michael, Sam ^*