Search Results - "Kukimoto-Niino, Mutsuko"

A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer

Suzuki, Mai^{Aff1, Aff2}, Uchibori, Ken^{Aff1, Aff3}, Oh-hara, Tomoko, Nomura, Yumi, Suzuki, Ryusei, Takemoto, Ai, Araki, Mitsugu, Matsumoto, Shigeyuki, Sagae, Yukari, Kukimoto-Niino, Mutsuko, Kawase, Yusuke, Shirouzu, Mikako, Okuno, Yasushi, Nishio, Makoto, Fujita, Naoya, Katayama, Ryohei^{Aff1, Aff2, IDs41698024005429_cor16}

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state

Kukimoto-Niino, Mutsuko, Katsura, Kazushige, Ishizuka-Katsura, Yoshiko, Mishima-Tsumagari, Chiemi, Yonemochi, Mayumi, Inoue, Mio, Nakagawa, Reiko, Kaushik, Rahul, Zhang, Kam Y.J., Shirouzu, Mikako

A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor

Furutani, Yutaka^{Aff1, Aff2, Aff3, Aff4, IDs4142002301755w_cor1}, Hirano, Yoshinori^{Aff5, Aff6}, Toguchi, Mariko, Higuchi, Shoko, Qin, Xian-Yang^{Aff2, Aff7}, Yanaka, Kaori^{Aff1, Aff2, Aff4}, Sato-Shiozaki, Yumi, Takahashi, Nobuaki, Sakai, Marina, Kongpracha, Pornparn^{Aff1, Aff4}, Suzuki, Takehiro, Dohmae, Naoshi, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Nagamori, Shushi^{Aff1, Aff4}, Suzuki, Harukazu, Kobayashi, Kaoru, Masaki, Takahiro, Koyama, Hiroo, Sekiba, Kazuma, Otsuka, Motoyuki^{Aff12, Aff13}, Koike, Kazuhiko, Kohara, Michinori, Kojima, Soichi, Kakeya, Hideaki, Matsuura, Tomokazu^{Aff1, Aff2, Aff4, Aff15}

Targeting Ras-binding domain of ELMO1 by computational nanobody design

Tam, Chunlai^{Aff1, Aff2}, Kukimoto-Niino, Mutsuko^{Aff3, IDs4200302304657w_cor2}, Miyata-Yabuki, Yukako, Tsuda, Kengo, Mishima-Tsumagari, Chiemi, Ihara, Kentaro, Inoue, Mio, Yonemochi, Mayumi, Hanada, Kazuharu, Matsumoto, Takehisa, Shirouzu, Mikako^{Aff3, Aff4}, Zhang, Kam Y. J.^{Aff1, Aff2, IDs4200302304657w_cor12}

Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery

Dileep, K.V., Ihara, Kentaro, Mishima-Tsumagari, Chiemi, Kukimoto-Niino, Mutsuko, Yonemochi, Mayumi, Hanada, Kazuharu, Shirouzu, Mikako, Zhang, Kam Y.J.

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Structural insights into the small GTPase specificity of the DOCK guanine nucleotide exchange factors

Kukimoto-Niino, Mutsuko, Ihara, Kentaro, Murayama, Kazutaka, Shirouzu, Mikako

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells.

Hou, Jiahui, Uejima, Tamami, Tanaka, Miho, Son, You Lee, Hanada, Kazuharu, Kukimoto-Niino, Mutsuko, Yamaguchi, Shigeru, Hashimoto, Shigeru, Yokoyama, Shigeyuki, Takemori, Toshitada, Saito, Takashi, Shirouzu, Mikako, Kondo, Toru

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Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor

Kukimoto-Niino, Mutsuko, Tsuda, Kengo, Ihara, Kentaro, Mishima-Tsumagari, Chiemi, Honda, Keiko, Ohsawa, Noboru, Shirouzu, Mikako

Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression

Katsura, Kazushige, Tomabechi, Yuri, Matsuda, Takayoshi, Yonemochi, Mayumi, Mikuni, Junko, Ohsawa, Noboru, Terada, Takaho, Yokoyama, Shigeyuki, Kukimoto-Niino, Mutsuko, Takemoto, Chie, Shirouzu, Mikako

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer

Mizuta, Hayato^{Aff1, Aff2}, Okada, Koutaroh^{Aff1, Aff3}, Araki, Mitsugu, Adachi, Jun, Takemoto, Ai, Kutkowska, Justyna, Maruyama, Kohei^{Aff1, Aff3}, Yanagitani, Noriko, Oh-hara, Tomoko, Watanabe, Kana, Tamai, Keiichi, Friboulet, Luc, Katayama, Kazuhiro, Ma, Biao, Sasakura, Yoko, Sagae, Yukari, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Takagi, Satoshi, Simizu, Siro, Nishio, Makoto, Okuno, Yasushi, Fujita, Naoya, Katayama, Ryohei^{Aff1, Aff3}

Reduced efficacy of a Src kinase inhibitor in crowded protein solution

Kasahara, Kento, Re, Suyong, Nawrocki, Grzegorz, Oshima, Hiraku, Mishima-Tsumagari, Chiemi, Miyata-Yabuki, Yukako, Kukimoto-Niino, Mutsuko, Yu, Isseki, Shirouzu, Mikako, Feig, Michael^Aff2, Sugita, Yuji^{Aff1, Aff5, Aff6}

Structural Insight into TNIK Inhibition.

Kukimoto-Niino, Mutsuko¹ (AUTHOR) kukimoto@riken.jp, Shirouzu, Mikako¹ (AUTHOR), Yamada, Tesshi² (AUTHOR)

Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen

Yuki, Hitomi, Kikuzato, Ko, Koda, Yasuko, Mikuni, Junko, Tomabechi, Yuri, Kukimoto-Niino, Mutsuko, Tanaka, Akiko, Shirai, Fumiyuki, Shirouzu, Mikako, Koyama, Hiroo, Honma, Teruki

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1

Tajiri, Hirotada, Uruno, Takehito, Shirai, Takahiro, Takaya, Daisuke, Matsunaga, Shigeki, Setoyama, Daiki, Watanabe, Mayuki, Kukimoto-Niino, Mutsuko, Oisaki, Kounosuke, Ushijima, Miho, Sanematsu, Fumiyuki, Honma, Teruki, Terada, Takaho, Oki, Eiji, Shirasawa, Senji, Maehara, Yoshihiko, Kang, Dongchon, Côté, Jean-François, Yokoyama, Shigeyuki, Kanai, Motomu, Fukui, Yoshinori

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Structural Basis for the Specific Recognition of the Major Antigenic Peptide from the Japanese Cedar Pollen Allergen Cry j 1 by HLA-DP5

Kusano, Seisuke, Kukimoto-Niino, Mutsuko, Satta, Yoko, Ohsawa, Noboru, Uchikubo-Kamo, Tomomi, Wakiyama, Motoaki, Ikeda, Mariko, Terada, Takaho, Yamamoto, Ken, Nishimura, Yasuharu, Shirouzu, Mikako, Sasazuki, Takehiko, Yokoyama, Shigeyuki

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