Search Results - "Lerit DA"

Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model.

Adebambo TH; Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA., Medina-Flores F; Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA., Zhang S; Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

Journal Article , 2025

Centrocortin potentiates co-translational localization of its mRNA to the centrosome via dynein.

Zein-Sabatto H; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322., Brockett JS; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322., Jin L; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, UK., Husbands CA; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322., Lee J; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322.; Present Address: University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104., Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322., Buehler J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322., Bullock SL; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, UK.; co-corresponding authors., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.; co-corresponding authors.

Journal Article; Preprint , 2024

Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model.

Adebambo TH; Department of Cell Biology, Emory University School of Medicine, Atlanta GA 30322., Flores MFM; Department of Cell Biology, Emory University School of Medicine, Atlanta GA 30322., Zhang SL; Department of Cell Biology, Emory University School of Medicine, Atlanta GA 30322., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta GA 30322.; Winship Cancer Institute, Emory University, Atlanta GA 30322.

Journal Article; Preprint , 2024

A missense SNP in the tumor suppressor SETD2 reduces H3K36me3 and mitotic spindle integrity in Drosophila.

Brockett JS; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Manalo T; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Zein-Sabatto H; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Lee J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Chu P; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Feng H; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Patil D; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Davidson P; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Ogan K; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Master VA; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Pattaras JG; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA., Roberts DL; Emory University Department of Medicine, Division of General Internal Medicine, Atlanta, GA 30322, USA., Bergquist SH; Emory University Department of Medicine, Division of General Internal Medicine, Atlanta, GA 30322, USA., Reyna MA; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Petros JA; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA., Arnold RS; Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural , 2024

The PCM scaffold enables RNA localization to centrosomes.

Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.; Equal contributions., Tian W; Equal contributions.; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322., Quintanilla MA; Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153., Beach JR; Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.

Journal Article; Preprint , 2024

Reflections on mentorship as an early career researcher.

Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.; Winship Cancer Institute, Emory University, Atlanta, GA 30322.

Journal Article , 2022

Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly.

Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2022

Signed, sealed, and delivered: RNA localization and translation at centrosomes.

Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.

Journal Article; Research Support, N.I.H., Extramural , 2022

Drosophila centrocortin is dispensable for centriole duplication but contributes to centrosome separation.

Mehta DS; College of Science and Mathematics, Augusta University, Augusta, GA 30912, USA., Zein-Sabatto H; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Ryder PV; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Wandrer, Atlanta, GA 30340, USA., Lee J; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322, USA., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Journal Article; Research Support, N.I.H., Extramural , 2022

The Identification and Functional Analysis of mRNA Localizing to Centrosomes.

Zein-Sabatto H; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States.

Journal Article; Review , 2021

Antagonism between germ cell-less and Torso receptor regulates transcriptional quiescence underlying germline/soma distinction.

Colonnetta MM; Department of Molecular Biology, Princeton University, Princeton, United States., Lym LR; Department of Cell Biology, Emory University School of Medicine, Atlanta, United States., Wilkins L; Department of Molecular Biology, Princeton University, Princeton, United States., Kappes G; Department of Molecular Biology, Princeton University, Princeton, United States., Castro EA; Department of Cell Biology, Emory University School of Medicine, Atlanta, United States., Ryder PV; Department of Cell Biology, Emory University School of Medicine, Atlanta, United States., Schedl P; Department of Molecular Biology, Princeton University, Princeton, United States., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, United States., Deshpande G; Department of Molecular Biology, Princeton University, Princeton, United States.

Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. , 2021

centrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis.

Ryder PV; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA., Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2020

Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells.

Robinson BV; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A., Faundez V; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review , 2020

Quantitative analysis of subcellular distributions with an open-source, object-based tool.

Ryder PV; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA dlerit@emory.edu ryderp@gmail.com., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA dlerit@emory.edu ryderp@gmail.com.

Journal Article; Research Support, N.I.H., Extramural , 2020

Drosophila pericentrin-like protein promotes the formation of primordial germ cells.

Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2020

Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary.

Benner L; Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.; Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218., Castro EA; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322., Whitworth C; Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.; Department of Biology, Indiana University, Bloomington, Indiana 47405., Venken KJT; Verna and Marrs McLean Department of Biochemistry and Molecular Biology.; McNair Medical Institute at the Robert and Janice McNair Foundation.; Dan L. Duncan Cancer Center, Center for Drug Discovery.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas 77030., Yang H; Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892., Fang J; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322., Oliver B; Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 briano@nih.gov dlerit@emory.edu., Cook KR; Department of Biology, Indiana University, Bloomington, Indiana 47405., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322 briano@nih.gov dlerit@emory.edu.

Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. , 2019

RNA localization regulates diverse and dynamic cellular processes.

Ryder PV; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia., Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia.

Journal Article; Research Support, N.I.H., Extramural; Review , 2018

Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation.

Lerit DA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: dlerit@emory.edu., Shebelut CW; School of Medicine, University of Virginia, Charlottesville, VA 22908, USA., Lawlor KJ; Department of Neuroscience, Columbia University, New York, NY 10032, USA., Rusan NM; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA., Gavis ER; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Schedl P; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119991, Russia., Deshpande G; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: gdeshpan@princeton.edu.

Journal Article , 2017

Centrosomes are multifunctional regulators of genome stability.

Lerit DA; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, MD, 20892, USA. dorothy.lerit@nih.gov.; National Institutes of Health, 50 South Drive, Building 50, Room 2122, Bethesda, MD, 20892, USA. dorothy.lerit@nih.gov., Poulton JS; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA. poultonj@email.unc.edu.; University of North Carolina, Fordham 519, CB#3280, Chapel Hill, NC, 27599, USA. poultonj@email.unc.edu.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review , 2016

Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function.

Lerit DA; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Jordan HA; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Poulton JS; Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Fagerstrom CJ; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Galletta BJ; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Peifer M; Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Rusan NM; Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 Nasser@nih.gov.

Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't , 2015