Sökresultat - "Müschen M"

Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation

McCracken, AN, McMonigle, RJ, Tessier, J, Fransson, R, Perryman, MS, Chen, B, Keebaugh, A, Selwan, E, Barr, SA, Kim, SM, Roy, SG, Liu, G, Fallegger, D, Sernissi, L, Brandt, C, Moitessier, N, Snider, AJ, Clare, S, Müschen, M, Huwiler, A, Kleinman, MT, Hanessian, S, Edinger, AL

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Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition

Köhrer, S, Havranek, O, Seyfried, F, Hurtz, C, Coffey, GP, Kim, E, ten Hacken, E, Jäger, U, Vanura, K, O'Brien, S, Thomas, DA, Kantarjian, H, Ghosh, D, Wang, Z, Zhang, M, Ma, W, Jumaa, H, Debatin, K-M, Müschen, M, Meyer, LH, Davis, RE, Burger, JA

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BCOR regulates myeloid cell proliferation and differentiation.

Cao, Q, Gearhart, MD, Gery, S, Shojaee, S, Yang, H, Sun, H, Lin, D-C, Bai, J-W, Mead, M, Zhao, Z, Chen, Q, Chien, W-W, Alkan, S, Alpermann, T, Haferlach, T, Müschen, M, Bardwell, VJ, Koeffler, HP

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Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia

Swaminathan, S, Klemm, L, Park, E, Papaemmanuil, E, Ford, A, Kweon, SM, Trageser, D, Hasselfeld, B, Henke, N, Mooster, J, Geng, H, Schwarz, K, Kogan, SC, Casellas, R, Schatz, DG, Lieber, MR, Greaves, MF, Müschen, M

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Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

Shojaee, S, Caeser, R, Buchner, M, Park, E, Swaminathan, S, Hurtz, C, Geng, H, Chan, LN, Klemm, L, Hofmann, WK, Qiu, YH, Zhang, N, Coombes, KR, Paietta, E, Molkentin, J, Koeffler, HP, Willman, CL, Hunger, SP, Melnick, A, Kornblau, SM, Müschen, M

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YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

Muschen, Markus, Chang, BH, Johnson, K, LaTocha, D, Rowley, JSJ, Bryant, J, Burke, R, Smith, RL, Loriaux, M, Müschen, M, Mullighan, C

Infectious origins of childhood leukemia

Muschen, Markus, Swaminathan, S, Müschen, M

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Muschen, Markus, Tsai, CT, Yang, PM, Chern, TR, Chuang, SH, Lin, JH, Klemm, L, Müschen, M, Chen, CC

Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL

Muschen, Markus, Fontanari, LM, Japp, AS, Krause, A, Mooster, J, Chopra, M, Müschen, M, Bohlander, SK

O-acetylated n-acetylneuraminic acid as a novel target for therapy in human pre-b acute lymphoblastic leukemia

Muschen, Markus, Parameswaran, R, Lim, M, Arutyunyan, A, Abdel-Azim, H, Hurtz, C, Lau, K, Müschen, M, Yu, RK, von, M, Heisterkamp, N

ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.

Thai, M, Ting, PY, McLaughlin, J, Cheng, D, Müschen, M, Witte, ON, Colicelli, J

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Development of resistance to dasatinib in Bcr/Abl-positive acute lymphoblastic leukemia

Fei, F, Stoddart, S, Müschen, M, Kim, Y-M, Groffen, J, Heisterkamp, N

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Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction.

Müschen, M, Re, D, Jungnickel, B, Diehl, V, Rajewsky, K, Küppers, R

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Rare occurrence of classical Hodgkin's disease as a T cell lymphoma.

Müschen, M, Rajewsky, K, Bräuninger, A, Baur, AS, Oudejans, JJ, Roers, A, Hansmann, ML, Küppers, R

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Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia

Gang, E J, Hsieh, Y-T, Pham, J, Zhao, Y, Nguyen, C, Huantes, S, Park, E, Naing, K, Klemm, L, Swaminathan, S, Conway, E M, Pelus, L M, Crispino, J, Mullighan, C G, McMillan, M, Müschen, M, Kahn, M^{Aff2, IDonc2013169_cor17}, Kim, Y-M

VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia

Mangum, D S, Downie, J, Mason, C C, Jahromi, M S, Joshi, D, Rodic, V, Müschen, M, Meeker, N, Trede, N^{Aff1, Aff2}, Frazer, J K, Zhou, Y, Cheng, C, Jeha, S, Pui, C-H, Willman, C L, Harvey, R C, Hunger, S P, Yang, J J, Barnette, P^{Aff1, Aff2}, Mullighan, C G, Miles, R R, Schiffman, J D^{Aff1, Aff2, IDleu2013223_cor22}

SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells

Sprangers, M, Feldhahn, N, Liedtke, S, Jumaa, H, Siebert, R, Müschen, M^{Aff1, ID1209520_cor6}

The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells

Sprangers, M, Feldhahn, N, Herzog, S, Hansmann, M-L, Reppel, M, Hescheler, J, Jumaa, H, Siebert, R, Müschen, M^{Aff1, ID1209510_cor9}

BCR–ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells

Klein, F, Feldhahn, N, Herzog, S, Sprangers, M, Mooster, J L, Jumaa, H, Müschen, M^{Aff1, ID1209133_cor7}