Sökresultat - "MCL-1"

MicroRNA-29b-3p reduces cisplatin resistance in non-small cell lung cancer by targeting myeloid cell leukemia-1

Cheng, Yuanjun^Aff1, Chen, Bin^Aff1, Dong, Xuxiao, Shu, Jian^{Aff2, IDs13273024004386_cor1}, Yao, Jie^{Aff1, IDs13273024004386_cor2}

Mcl-1 is an important target protein for kaempferol from persimmon leaves in sensitizing ABT-199 to induce apoptosis in hepatoma cancer cells

Chen, Li^{Aff1, Aff2}, Jiang, Xu Dong, Liu, Xue Ping, Lee, Yu Zhao, Tham, Chau Ling^{Aff4, Aff5}, Yusof, Rohana, Gao, Si^{Aff2, IDs12032025026963_cor1}, Lee, Ming Tatt^{Aff1, Aff7, IDs12032025026963_cor2}

Overexpression of MCL-1 in canine hepatocellular carcinoma and its efficacy as a prognostic marker

Jehun Baek, Jaeho Cho, Hun-kyeong Shin, Wan Hee Kim

electronic resource

Visa

A combination of Dihydroartemisinin and Venetoclax enhances antitumor effect in AML via C-MYC/BCL-XL/MCL-1 triple targeting

Fenglin Li, Yao Chen, Haihui Zhuang, Renzhi Pei, Yuyu Lu, Dong chen, Shuangyue Li, Peipei Ye, Jiaying lian, Ying Lu

electronic resource

Visa

Structural basis of BAK sequestration by MCL-1 in apoptosis

Srivastava, Shagun ^{1, 9}, Sekar, Giridhar ^{2, 9}, Ojoawo, Adedolapo ^{2, 3, 9}, Aggarwal, Anup ^{2, 4, 9}, Ferreira, Elisabeth ¹, Uchikawa, Emiko ⁵, Yang, Meek ⁶, Grace, Christy R. ², Dey, Raja ¹, Lin, Yi-Lun ², Guibao, Cristina D. ², Jayaraman, Seetharaman ^{2, 7}, Mukherjee, Somnath ⁸, Kossiakoff, Anthony A. ⁸, Dong, Bin ⁶, Myasnikov, Alexander ⁵, Moldoveanu, Tudor ^{1, 10, ∗}

Flow cytometric expression of Bcl-2, Mcl-1, and their ratios correlates with primary and secondary cytogenetic changes and their combinations in multiple myeloma

Singla, Shelly^Aff1, Sreedharanunni, Sreejesh^{Aff1, IDs00277024060043_cor1}, Singh, Archana, Singh, Charanpreet, Bose, Parveen, Kumar, Arun, Balakrishnan, Anand, Jain, Arihant, Khadwal, Alka, Lad, Deepesh, Prakash, Gaurav, Sharma, Praveen, Mallik, Nabhajit, Sachdeva, Man Updesh Singh, Das, Reena, Malhotra, Pankaj

The Role of miR-29a and miR-143 on the Anti-apoptotic MCL-1/cIAP-2 Genes Expression in EGFR Mutated Non-small Cell Lung Carcinoma Patients

Abrehdari-Tafreshi, Zahra^{Aff1, IDs10528024107406_cor1}, Arefian, Ehsan^{Aff2, Aff3}, Rakhshani, Nasser, Najafi, S. Mahmoud A.^{Aff1, IDs10528024107406_cor4}

BCL-2 Protein Family Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy

Garner, Thomas P.^{Aff3, Aff4, Aff5, Aff6}, Gavathiotis, Evripidis^{Aff3, Aff4, Aff5, Aff6}

Gavathiotis, Evripidis^Aff2, Walker, John M.^Aff1

20(S)-protopanaxadiol inhibits proliferation and induces apoptosis of acute myeloid leukemia cells via targeting Bcl-XL and MCL-1

Meng Xu, Feng Hao, Shuangshuang Wu, Zhanning Qu, Junying Li, Shuang Chen, Fang Fang, Yundong Zhao, Cheng Hu

electronic resource

Visa; Visa

Discovery of benzethonium chloride as a potent STAT3 inhibitor for the treatment of HNSCC

Yuefeng Han, Shumin Li, Deshang Chen, Mingjie Zhang, Guoying Han, QianQian Xu, Xianming Ge, Mengli Wang, Yan Pan, Sien Ma, Beibei Xu, Mengmeng Deng, Bao Zhao

electronic resource

Visa; Visa

A phase 1b study of venetoclax and alvocidib in patients with relapsed/refractory acute myeloid leukemia

Jonas, Brian A, Hou, Jing‐Zhou, Roboz, Gail J, Alvares, Caroline L, Jeyakumar, Deepa, Edwards, John R, Erba, Harry P, Kelly, Richard J, Röllig, Christoph, Fiedler, Walter, Brackman, Deanna, Siddani, Satya R, Chyla, Brenda, Hilger‐Rolfe, Jacqueline, Watts, Justin M

application/pdf

Synthesis, Biological Evaluation, and Molecular Docking Studies of 7-Azaindole-Acylsulfonamide Derivatives as Mcl-1 Inhibitors

Yan, Zixue, Zhou, Le, Cheng, Zhiyun, Jiang, Haiqing, Zhang, Yihan, Deng, Ritian, Wan, Yichao^{Aff1, IDS1070363224090226_cor7}

Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma

Liu, Tingyu, Yue, Xin^{Aff2, IDs13402024009279_cor2}, Chen, Xue, Yan, Ru, Wu, Chong, Li, Yunzhi, Bu, Xianzhang, Han, Hui^{Aff1, IDs13402024009279_cor8}, Liu, Ran-Yi^{Aff1, IDs13402024009279_cor9}

USP13 promotes proliferation and angiogenesis of diffuse large B-cell lymphoma cells by promoting MCL-1 expression

Yang, Huiyun, Chen, Tianping, Fan, Minxia, Xu, Weihua, Wu, Xiuwei^{Aff3, IDs1327302300367w_cor5}

Osteosarcoma cells depend on MCL-1 for survival, and osteosarcoma metastases respond to MCL-1 antagonism plus regorafenib in vivo

Yanhao Ji, Michael A. Harris, Lucas M. Newton, Tiffany J. Harris, W. Douglas Fairlie, Erinna F. Lee, Christine J. Hawkins

electronic resource

Visa

NL101 synergizes with the BCL-2 inhibitor venetoclax through PI3K-dependent suppression of c-Myc in acute myeloid leukaemia

Lu, Ying^{Aff1, Aff3}, Jiang, Xia^{Aff1, Aff2, Aff3}, Li, Youhong^{Aff1, Aff2, Aff3}, Li, Fenglin^{Aff1, Aff3}, Zhao, Mengting, Lin, Ye, Jin, Lili^{Aff1, Aff2, Aff3}, Zhuang, Haihui^{Aff1, Aff3}, Li, Shuangyue^{Aff1, Aff3}, Ye, Peipei^{Aff1, Aff3}, Pei, Renzhi^{Aff1, Aff3}, Jin, Jie, Jiang, Lei^{Aff1, Aff2, IDs12967024056470_cor13}

The CDK9 inhibitor enitociclib overcomes resistance to BTK inhibition and CAR-T therapy in mantle cell lymphoma

Jiang, Vivian, Lee, William, Zhang, Tianci, Jordan, Alexa, Yan, Fangfang, Cai, Qingsong, McIntosh, Joseph, Vargas, Jovanny, Liu, Yang, Wang, Michael^{Aff1, Aff2, IDs40364024005897_cor10}

The pan-BH-3 mimetic, obatoclax, synergistically enhances cisplatin-induced apoptosis in oral squamous cell carcinoma through a mechanism that involves degradation of the pro-survival protein Mcl-1

Gao, Tianyi ^⁎, Magnano, Stefania, Quadros, Molly, Barroeta, Patricia Hannon, Zisterer, Daniela M.

Low extracellular pH enhances TRAIL-induced apoptosis by downregulating Mcl-1 expression

Vafaeinik, Farzaneh ^a, Zhang, Lin ^{b, c}, Lee, Yong J. ^{a, ⁎}

Synergistic activity of S63845 and parthenolide to overcome acquired resistance to MEK1/2 inhibitor in melanoma cells: Mechanisms and therapeutic potential

Hartman, Mariusz L., Sztiller-Sikorska, Malgorzata, Czyz, Malgorzata ^⁎