Sökresultat - "Magnuson, Steven R."

GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1

Taylor, Alexander M.^aff1, Bailey, Chris^aff1, Belmont, Lisa D.^aff2, Campbell, Robert^aff1, Cantone, Nico^aff1, Côté, Alexandre^aff1, Crawford, Terry D.^aff2, Cummings, Richard^aff1, DeMent, Kevin^aff2, Duplessis, Martin^aff1, Flynn, Megan^aff2, Good, Andrew C.^aff1, Huang, Hon-Ren^aff1, Joshi, Shivangi^aff1, Leblanc, Yves^aff1, Murray, Jeremy^aff2, Nasveschuk, Christopher G.^aff1, Neiss, Adrianne^aff1, Poy, Florence^aff1, Romero, F. Anthony^aff2, Sandy, Peter^aff1, Tang, Yong^aff1, Tsui, Vickie^aff2, Zawadzke, Laura^aff1, Sims, Robert J., III^aff1, Audia, James E.^aff1, Bellon, Steven F.^aff1, Magnuson, Steven R.^aff2, Albrecht, Brian K.^aff1, Cochran, Andrea G.^aff2

GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1‑like

Wang, Shumei^aff1, Tsui, Vickie^aff1, Crawford, Terry D.^aff1, Audia, James E.^aff2, Burdick, Daniel J.^aff1, Beresini, Maureen H.^aff1, Côté, Alexandre, Cummings, Richard^aff2, Duplessis, Martin^aff2, Flynn, E. Megan^aff1, Hewitt, Michael C.^aff2, Huang, Hon-Ren^aff2, Jayaram, Hariharan^aff2, Jiang, Ying^aff3, Joshi, Shivangi^aff2, Murray, Jeremy^aff1, Nasveschuk, Christopher G.^aff2, Pardo, Eneida^aff2, Poy, Florence^aff2, Romero, F. Anthony^aff1, Tang, Yong^aff2, Taylor, Alexander M.^aff2, Wang, Jian^aff3, Xu, Zhaowu^aff3, Zawadzke, Laura E.^aff2, Zhu, Xiaoyu^aff3, Albrecht, Brian K.^aff2, Magnuson, Steven R.^aff1, Bellon, Steve^aff2, Cochran, Andrea G.^aff1

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Crawford, Terry D.^aff1, Tsui, Vickie^aff1, Flynn, E. Megan^aff1, Wang, Shumei^aff1, Taylor, Alexander M.^aff2, Côté, Alexandre^aff2, Audia, James E.^aff2, Beresini, Maureen H.^aff1, Burdick, Daniel J.^aff1, Cummings, Richard^aff2, Dakin, Les A.^aff2, Duplessis, Martin^aff2, Good, Andrew C.^aff2, Hewitt, Michael C.^aff2, Huang, Hon-Ren^aff2, Jayaram, Hariharan^aff2, Kiefer, James R.^aff1, Jiang, Ying^aff3, Murray, Jeremy^aff1, Nasveschuk, Christopher G.^aff2, Pardo, Eneida^aff2, Poy, Florence^aff2, Romero, F. Anthony^aff1, Tang, Yong^aff2, Wang, Jian^aff3, Xu, Zhaowu^aff3, Zawadzke, Laura E.^aff2, Zhu, Xiaoyu^aff3, Albrecht, Brian K.^aff2, Magnuson, Steven R.^aff1, Bellon, Steve^aff2, Cochran, Andrea G.^aff1

Discovery of Selective 4‑Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization

Crawford, Terry D., Ndubaku, Chudi O., Chen, Huifen, Boggs, Jason W., Bravo, Brandon J., DeLaTorre, Kelly, Giannetti, Anthony M., Gould, Stephen E., Harris, Seth F., Magnuson, Steven R., McNamara, Erin, Murray, Lesley J., Nonomiya, Jim, Sambrone, Amy, Schmidt, Stephen, Smyczek, Tanya, Stanley, Mark, Vitorino, Philip, Wang, Lan, West, Kristina, Wu, Ping, Ye, Weilan

Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Hanan, Emily J.^aff1d1, van Abbema, Anne^aff1d2, Barrett, Kathy^aff1d2, Blair, Wade S.^aff1d2, Blaney, Jeff^aff1d1, Chang, Christine^aff1d2, Eigenbrot, Charles^aff1d3, Flynn, Sean^aff2, Gibbons, Paul^aff1d1, Hurley, Christopher A.^aff2, Kenny, Jane R.^aff1d4, Kulagowski, Janusz^aff2, Lee, Leslie^aff1d5, Magnuson, Steven R.^aff1d1, Morris, Claire^aff2, Murray, Jeremy^aff1d3, Pastor, Richard M.^aff1d1, Rawson, Tom^aff1d1, Siu, Michael^aff1d1, Ultsch, Mark^aff1d3, Zhou, Aihe^aff1d1, Sampath, Deepak^aff1d5, Lyssikatos, Joseph P.^aff1d1

Cyclopentannulation by an Iterative Process of Sequential Claisen Rearrangement and Enyne Radical Closure: Routes to Triquinane and Propellane Systems and Use in the Synthesis of (±)-Ceratopicanol

Clive, D. L. J., Magnuson, Steven R., Manning, Hartford W., Mayhew, Darrin L.

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition

Ghosh, Srimoyee, Taylor, Alexander, Chin, Melissa, Huang, Hon-Ren, Conery, Andrew R., Mertz, Jennifer A., Salmeron, Andres, Dakle, Pranal J., Mele, Deanna, Cote, Alexandre, Jayaram, Hari, Setser, Jeremy W., Poy, Florence, Hatzivassiliou, Georgia, DeAlmeida-Nagata, Denise, Sandy, Peter, Hatton, Charlie, Romero, F. Anthony, Chiang, Eugene, Reimer, Thornik, Crawford, Terry, Pardo, Eneida, Watson, Venita G., Tsui, Vickie, Cochran, Andrea G., Zawadzke, Laura, Harmange, Jean-Christophe, Audia, James E., Bryant, Barbara M., Cummings, Richard T., Magnuson, Steven R., Grogan, Jane L., Bellon, Steve F., Albrecht, Brian K., Sims, Robert J., III, Lora, Jose M.

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2)

Crawford, Terry D.^aff1, Audia, James E.^aff2, Bellon, Steve^aff2, Burdick, Daniel J.^aff1, Bommi-Reddy, Archana^aff2, Côté, Alexandre^aff2, Cummings, Richard T.^aff2, Duplessis, Martin^aff2, Flynn, E. Megan^aff1, Hewitt, Michael^aff2, Huang, Hon-Ren^aff2, Jayaram, Hariharan^aff2, Jiang, Ying^aff3, Joshi, Shivangi^aff2, Kiefer, James R.^aff1, Murray, Jeremy^aff1, Nasveschuk, Christopher G.^aff2, Neiss, Arianne^aff2, Pardo, Eneida^aff2, Romero, F. Anthony^aff1, Sandy, Peter^aff2, Sims, Robert J., III^aff2, Tang, Yong^aff2, Taylor, Alexander M.^aff2, Tsui, Vickie^aff1, Wang, Jian^aff3, Wang, Shumei^aff1, Wang, Yongyun^aff3, Xu, Zhaowu^aff3, Zawadzke, Laura^aff2, Zhu, Xiaoqin^aff3, Albrecht, Brian K.^aff2, Magnuson, Steven R.^aff1, Cochran, Andrea G.^aff1

Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance

Crawford, Terry D., Vartanian, Steffan, Côté, Alexandre, Bellon, Steve, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Zawadzke, Laura, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G., Stokoe, David

A Concise Total Synthesis of Dysidiolide through Application of a Dioxolenium-Mediated Diels−Alder Reaction

Magnuson, Steven R., Sepp-Lorenzino, Laura, Rosen, Neal, Danishefsky, Samuel J.

Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors

Wang, Lan, Stanley, Mark, Boggs, Jason W., Crawford, Terry D., Bravo, Brandon J., Giannetti, Anthony M., Harris, Seth F., Magnuson, Steven R., Nonomiya, Jim, Schmidt, Stephen, Wu, Ping, Ye, Weilan, Gould, Stephen E., Murray, Lesley J., Ndubaku, Chudi O., Chen, Huifen

Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles

René, Olivier, Souverneva, Alexandra, Magnuson, Steven R., Fauber, Benjamin P.

Discovery of Selective 4-Amino-pyridopyrimidineInhibitors of MAP4K4 Using Fragment-Based Lead Identification andOptimization.

Crawford, Terry D.¹, Ndubaku, Chudi O.¹, Chen, Huifen¹, Boggs, Jason W.¹, Bravo, Brandon J.¹, De La Torre, Kelly¹, Giannetti, Anthony M.¹, Gould, Stephen E.¹, Harris, Seth F.¹, Magnuson, Steven R.¹, McNamara, Erin¹, Murray, Lesley J.¹, Nonomiya, Jim¹, Sambrone, Amy¹, Schmidt, Stephen¹, Smyczek, Tanya¹, Stanley, Mark¹, Vitorino, Philip¹, Wang, Lan¹, West, Kristina¹

Discovery of Potent andSelective PyrazolopyrimidineJanus Kinase 2 Inhibitors.

Hanan, EmilyJ.¹, van Abbema, Anne¹, Barrett, Kathy¹, Blair, Wade S.¹, Blaney, Jeff¹, Chang, Christine¹, Eigenbrot, Charles¹, Flynn, Sean¹, Gibbons, Paul¹, Hurley, ChristopherA.¹, Kenny, Jane R.¹, Kulagowski, Janusz¹, Lee, Leslie¹, Magnuson, Steven R.¹, Morris, Claire¹, Murray, Jeremy¹, Pastor, RichardM.¹, Rawson, Tom¹, Siu, Michael¹, Ultsch, Mark¹

Cyclopentannulation by an iterative process of sequential...

D.L.J. Clive, Magnuson, Steven R.

Synthesis of the sesquiterpene (±)-ceratopicanol: Use of radicals derived from epoxides

Clive, Derrick L.J., Magnuson, Steven R.