Search Results - "Mendelian Randomization Analysis"

Causal validation of the relationship between air pollution and lung cancer: A bidirectional Mendelian randomization study and meta-analysis.

Wang X; The First People's Hospital of Kunming City and Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Xiao G; Zhoupu Hospital, Pudong New District, Shanghai, China., Xu W; The First People's Hospital of Kunming City and Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Ni C; The First People's Hospital of Kunming City and Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.

Journal Article; Meta-Analysis , 2025

Exploring the Causal Relationship Between Immune Cells and Idiopathic Pulmonary Fibrosis: A Mendelian Randomization Analysis.

Gong P; School of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi, China.; Shouyang County People's Hospital, Shouyang, Shanxi, China., Lu Y; School of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi, China., Chai X; School of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi, China., Li X; School of Basic Medical Sciences, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi, China.

Journal Article , 2025

Causal association between oral microbiota and oral cancer: a mendelian randomization study.

Wu Z; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Peng Q; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Ren Z; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Xu X; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Jiang X; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Yang W; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China., Han Y; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Oyang L; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Lin J; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Peng M; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Wu N; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Tang Y; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China., Liao Q; Department of Oncology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, Hunan, P. R. China. march-on@126.com., Zhou Y; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China. yujany_zhou@163.com.; Hunan Engineering Research Center of Tumor organoid Technology and application, Public Service Platform of Tumor organoids Technology, 283 Tongzipo Road, Changsha, 410013, Hunan, China. yujany_zhou@163.com.; Hunan Key Laboratory of Cancer Metabolism, The Affiliated Cancer Hospital of Xiangya School of Medicine, Hunan Cancer Hospital, Central South University, 283 Tongzipo Road, Changsha, 410013, Hunan, China. yujany_zhou@163.com.

Journal Article , 2025

Mendelian randomization combined with single-cell sequencing data analysis of chemokines and chemokine receptors and key genes and molecular mechanisms associated with epilepsy.

Zhang LM; Department of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Zeng T; Department of Neurology, The Pearl River Hospital Affiliated to Southern Medical University, Guangzhou, Guangdong, China., Zhang BR; Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Zhang QJ; Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Gao SJ; Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Zhu YL; Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Liu MW; Department of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, Yunnan, China.

Journal Article , 2025

Plasma Metabolites as Mediators Between Gut Microbiota and Parkinson's Disease: Insights from Mendelian Randomization.

Chen J; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Zhu L; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Wang F; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Zhu Y; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Chen J; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Liang C; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Liu B; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China., Pang A; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China. 879384106@qq.com., Yang X; Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China. yxldoc11@163.com.

Journal Article , 2025

The causal effects of systemic antioxidant capacity on male infertility: A two-sample mendelian randomization analysis.

Zhang X; Department of Urology, Shaoxing People's Hospital(The First Affiliated Hospital, Shaoxing University), 568 Zhongxing North Road, 312000, Shaoxing, Zhejiang, China., Zhu Z; Department of Urology, Shaoxing People's Hospital(The First Affiliated Hospital, Shaoxing University), 568 Zhongxing North Road, 312000, Shaoxing, Zhejiang, China., Shen C; Department of Urology, Shaoxing People's Hospital(The First Affiliated Hospital, Shaoxing University), 568 Zhongxing North Road, 312000, Shaoxing, Zhejiang, China., Tang G; Department of Urology, Shaoxing People's Hospital(The First Affiliated Hospital, Shaoxing University), 568 Zhongxing North Road, 312000, Shaoxing, Zhejiang, China. tangguiliangsx@126.com.

Journal Article , 2025

Challenges in interpreting Mendelian randomization studies with a disease as the exposure: Using COVID-19 liability studies as an exemplar.

Chen S; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Liang Y; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Mo JMY; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Li QHY; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., He B; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Luo S; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Burgess S; MRC Biostatistics Unit, Cambridge Institute of Public Health, University of Cambridge, Cambridge, United Kingdom., Au Yeung SL; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. ayslryan@hku.hk.

Journal Article; Systematic Review , 2025

Causal Effects From Kidney Function to Plasma Proteome: Integrated Observational and Mendelian Randomization Analysis With >50,000 UK Biobank Participants.

Cho JM; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gyeonggi-do, South Korea., Kim M; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea., Oh J; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea., Koh JH; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea., Cho S; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gyeonggi-do, South Korea., Kim Y; Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea., Lee S; Department of Internal Medicine, Uijeongbu Eulji University Medical Center, Seoul, South Korea., Kim K; Transdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Seoul, South Korea., Kim YC; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Han SS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Joo KW; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Kim YS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Lee H; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Kim DK; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea., Park S; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.

Journal Article , 2025

Causal Inference of Different Smoke Exposure Statuses and Influenza Risk: Insights From a Mendelian Randomization Study.

Guo Y; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, Hangzhou, China., Chen H; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, Hangzhou, China., Wu S; Center for Nephrology and Clinical Metabolomics and Division of Nephrology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China., Zhou J; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, Hangzhou, China., Chen Z; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, Hangzhou, China.

Journal Article , 2025

Sex-specific Mendelian randomization phenome-wide association study of basal metabolic rate.

Ng JCM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China., Schooling CM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China. cms1@hku.hk.; Graduate School of Public Health and Health Policy, The City University of New York, 55 West 125th St, New York, NY, 10027, USA. cms1@hku.hk.

Journal Article , 2025

Glaucoma and brain functional networks: a bidirectional Mendelian randomisation study.

Shu L; Fudan University Eye Ear Nose and Throat Hospital Department of Ophthalmology, Shanghai, China., Chen X; Fudan University Eye Ear Nose and Throat Hospital Department of Ophthalmology, Shanghai, China., Sun X; Department of Ophthalmology & Visual Science, Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China xhsun@shmu.edu.cn.; Fudan University Institutes of Brain Science, Shanghai, China.

Journal Article , 2025

Association between clonal hematopoiesis and periodontitis: a two-sample mendelian randomization study.

Qiu F; Wuxi School of Medicine, Jiangnan University, Wuxi, 214122, Jiangsu, China., Shao W; Wuxi School of Medicine, Jiangnan University, Wuxi, 214122, Jiangsu, China., Qin X; Wuxi School of Medicine, Jiangnan University, Wuxi, 214122, Jiangsu, China., Xu R; Affiliated Hospital of Jiangnan University, Comprehensive Building, No. 1000, Hefeng Road, Binhu District, Wuxi City, 214125, Jiangsu Province, China., Lu H; Affiliated Hospital of Jiangnan University, Comprehensive Building, No. 1000, Hefeng Road, Binhu District, Wuxi City, 214125, Jiangsu Province, China. LuHua1969@outlook.com.

Journal Article , 2025

Uncovering leading compounds for alzheimer's disease treatment: mendelian randomization and virtual screening insights into plasma protein modulation.

Sun X; School of Science, Hong Kong University of Science and Technology, Hong Kong, People's Republic of China., Hu X; Department of Nuclear Medicine, Southwest Hospital, Third Military Medical University, Chongqing, China., Wei J; Central Diagnostics Laboratory, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands., An H; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK. c4003171@newcastle.ac.uk.

Journal Article , 2025

Investigation of brain structures and potential mechanisms associated with ADHD: Insights from Mendelian randomization and genetic analysis.

Hu X; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, China; Guangdong Clinical Research Academy of Chinese Medicine, China., Lin L; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, China; Guangzhou University of Chinese Medicine, China., Wu Z; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, China; Guangzhou University of Chinese Medicine, China.

Journal Article , 2025

Bidirectional Mendelian randomization analysis of plasma lipidome and psychiatric disorders.

Yu L; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Long Q; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Zhang Y; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China; Department of Psychiatry, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China., Liu Y; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Guo Z; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Cao X; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Qin F; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Xu Y; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Qian Q; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Gao B; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China., Chen J; Department of Gastroenterology, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China., Liu J; Department of Dermatology and Venereology, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China., Zeng Y; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China; Department of Psychiatry, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China. Electronic address: zengyong@kmmu.edu.cn., Teng Z; Key Laboratory of Neurological and Psychiatric Disease Research of Yunnan Province, The Second Affiliated Hospital of Kunming Medical University, Kunming, China. Electronic address: tengzhaowei@kmmu.edu.cn.

Journal Article , 2025

Causal link between gut microbiota and obsessive-compulsive disorder: A two-sample Mendelian randomization analysis.

He M; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Zhang H; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Luo Z; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Duan X; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Zhao F; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Su P; Department of Occupational and Environmental Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Zeng Z; Department of Occupational and Environmental Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Zhou L; Department of Occupational and Environmental Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China., Chen C; Department of Occupational and Environmental Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China. Electronic address: chengzhichen@cqmu.edu.cn., Qiu J; Department of Health Laboratory Technology, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Research Center for Environment and Human Health, School of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China. Electronic address: 102335@cqmu.edu.cn.

Journal Article , 2025

Proteome-wide Mendelian randomization reveals causal associations between plasma proteins and autoimmune thyroid disease.

Li Y; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Zhu W; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Chen Y; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Kang Q; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Zhang Y; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Yang P; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Wang S; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China., Liu C; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China. lc_ahmu@163.com., Zhang Y; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China. zy18356056506@163.com., Zhang Q; Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China. zhangqiu@ahmu.edu.cn.

Journal Article , 2025

A flexible machine learning Mendelian randomization estimator applied to predict the safety and efficacy of sclerostin inhibition.

Legault MA; Department of Computer Science, McGill University, Montreal, QC, Canada; Mila, Montreal, QC, Canada; Faculté de pharmacie, Université de Montréal, Montreal, QC, Canada; Centre de recherche Azrieli du CHU Sainte-Justine, Montreal, QC, Canada. Electronic address: marc-andre.legault.1@umontreal.ca., Hartford J; Valence Labs, Montreal, QC, Canada., Arsenault BJ; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada; Department of Medicine, Faculty of Medicine, Université Laval, Quebec, QC, Canada., Yang AY; Mila, Montreal, QC, Canada; Department of Mathematics and Statistics, McGill University, Montreal, QC, Canada., Pineau J; Department of Computer Science, McGill University, Montreal, QC, Canada; Mila, Montreal, QC, Canada.

Journal Article , 2025

Causal relationship between immune cells and osteoporosis based on genetic prediction: a bidirectional two-sample mediated Mendelian randomization analysis.

Wang H; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China., Yu Z; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China., Chen B; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China., Xu S; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China., Zhou Y; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China., Tang X; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China. tangxf921@gmail.com.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China. tangxf921@gmail.com., Qin Y; Department of Orthopaedics, The Second Hospital of Jilin University, Jilin University, Changchun, 130041, People's Republic of China. qinyg@jlu.edu.cn.; Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Jilin University, Changchun, 130041, People's Republic of China. qinyg@jlu.edu.cn.

Journal Article , 2025

Causal role of immune cells in varicose veins: insights from a Mendelian randomization study.

Zhang QF; Department of Andrology, Department of Urology, Guilin People's Hospital, Guilin, 541002, China., Liu QL; Department of Vascular Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, China. wangyi243265@163.com.

Journal Article , 2025