Search Results - "Mörtl, Mario"

  • Showing 1 - 9 results of 9
Refine Results
  1. 1
    The Rational Design of Selective Benzoxazepin Inhibitors of the α‑Isoform of Phosphoinositide 3‑Kinase Culminating in the Identification of (S)‑2-((2-(1-Isopropyl‑1H‑1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2‑d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)

    The Rational Design of Selective Benzoxazepin Inhibitors of the α‑Isoform of Phosphoinositide 3‑Kinase Culminating in the Identification of (S)‑2-((2-(1-Isopropyl‑1H‑1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2‑d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)

    Heffron, Timothy P.aff1, Heald, Robert A.aff2, Ndubaku, Chudiaff1, Wei, BinQingaff1, Augistin, Martinaff3, Do, Stevenaff1, Edgar, Kyleaff1, Eigenbrot, Charlesaff1, Friedman, Loriaff1, Gancia, Emanuelaaff2, Jackson, Philip S.aff2, Jones, Grahamaff2, Kolesnikov, Aleksanderaff1, Lee, Leslie B.aff1, Lesnick, John D.aff1, Lewis, Cristinaaff1, McLean, Nevilleaff2, Mörtl, Marioaff3, Nonomiya, Jimaff1, Pang, Jodieaff1, Price, Steveaff2, Prior, Wei Weiaff1, Salphati, Laurentaff1, Sideris, Steveaff1, Staben, Steven T.aff1, Steinbacher, Stefanaff3, Tsui, Vickieaff1, Wallin, Jeffreyaff1, Sampath, Deepakaff1, Olivero, Alan G.aff1

    Save to List
  2. 2
    Discovery and Optimization of a Novel Series of Potent Mutant B‑RafV600E Selective Kinase Inhibitors

    Discovery and Optimization of a Novel Series of Potent Mutant B‑RafV600E Selective Kinase Inhibitors

    Vasbinder, Melissa M.aff1d1, Aquila, Brianaff1d1, Augustin, Martinaff5, Chen, Huaweiaff1d1, Cheung, Tonyaff1d1, Cook, Donaldaff1d1, Drew, Lisaaff1d1, Fauber, Benjamin P.aff1d1, Glossop, Steveaff3d4, Grondine, Michaelaff1d1, Hennessy, Edwardaff1d1, Johannes, Jeffreyaff1d1, Lee, Stephenaff1d1, Lyne, Paulaff1d1, Mörtl, Marioaff5, Omer, Charlesaff1d1, Palakurthi, Sangeethaaff1d1, Pontz, Timothyaff1d1, Read, Jonaff3d3, Sha, Liaff1d1, Shen, Minhuiaff1d1, Steinbacher, Stefanaff5, Wang, Haixiaaff1d1, Wu, Allanaff1d2, Ye, Minweiaff1d1

    Save to List
  3. 3
    The E. coli Effector Protein NleF Is a Caspase Inhibitor.

    The E. coli Effector Protein NleF Is a Caspase Inhibitor.

    Blasche, Sonja1, Mörtl, Mario2, Steuber, Holger2, Siszler, Gabriella1, Nisa, Shahista3, Schwarz, Frank1, Lavrik, Inna4, Gronewold, Thomas M. A.5, Maskos, Klaus2, Donnenberg, Michael S.3, Ullmann, Dirk2, Uetz, Peter6 uetz@vcu.edu, Kögl, Manfred1

    PDF Full Text
    Save to List
  4. 4
    The Rational Design of Selective Benzoxazepin Inhibitors of the a-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)

    The Rational Design of Selective Benzoxazepin Inhibitors of the a-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)

    Heffron, Timothy P.1 theffron@gene.com, Heald, Robert A.2, Ndubaku, Chudi1, BinQing Wei1, Augistin, Martin3, Do, Steven1, Edgar, Kyle1, Eigenbrot, Charles1, Friedman, Lori1, Gancia, Emanuela2, Jackson, Philip S.2, Jones, Graham2, Kolesnikov, Aleksander1, Lee, Leslie B.1, Lesnick, John D.1, Lewis, Cristina1, McLean, Neville2, Mörtl, Mario3, Nonomiya, Jim1, Pang, Jodie1

    Linked Full Text
    Save to List
  5. 5
    Discovery and Optimization of a Novel Series of Potent Mutant B‑RafV600E Selective Kinase Inhibitors.

    Discovery and Optimization of a Novel Series of Potent Mutant B‑RafV600E Selective Kinase Inhibitors.

    Vasbinder, Melissa M.1 melissa.vasbinder@astrazeneca.com, Aquila, Brian, Augustin, Martin2, Chen, Huawei, Cheung, Tony, Cook, Donald, Drew, Lisa, Fauber, Benjamin P., Glossop, Steve, Grondine, Michael, Hennessy, Edward, Johannes, Jeffrey, Lee, Stephen, Lyne, Paul, Mörtl, Mario2, Omer, Charles, Palakurthi, Sangeetha, Pontz, Timothy, Read, Jon, Sha, Li

    Linked Full Text
    Save to List
  6. 6
    The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.

    The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.

    Mörtl, Mario, Sonderegger, Peter, Diederichs, Kay, Welte, Wolfram

    Save to List
  7. 7
    Structure-Function Correlation in Glycine Oxidase from Bacillus subtilis.

    Structure-Function Correlation in Glycine Oxidase from Bacillus subtilis.

    Mörtl, Mario1, Diederich, Kay1, Welte, Wolfram1, Molla, Gianluca2, Motteran, Laura2, Andriolo, Gabriella2, Pilone, Mirella S.2, Pollegioni, Loredano2 loredano.pollegioni@uninsubria.it

    Linked Full Text
    Save to List
  8. 8
    Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.

    Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.

    Gerritz SW; Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA. samuel.gerritz@bms.com, Cianci C, Kim S, Pearce BC, Deminie C, Discotto L, McAuliffe B, Minassian BF, Shi S, Zhu S, Zhai W, Pendri A, Li G, Poss MA, Edavettal S, McDonnell PA, Lewis HA, Maskos K, Mörtl M, Kiefersauer R, Steinbacher S, Baldwin ET, Metzler W, Bryson J, Healy MD, Philip T, Zoeckler M, Schartman R, Sinz M, Leyva-Grado VH, Hoffmann HH, Langley DR, Meanwell NA, Krystal M

    Journal Article , 2011

    Save to List
  9. 9
    The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.

    The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.

    Mörtl M; University of Konstanz, Department of Biology, Konstanz, Germany., Sonderegger P, Diederichs K, Welte W

    Journal Article; Research Support, Non-U.S. Gov't , 2007

    Save to List

Search Tools: