Sökresultat - "PHGDH"

Activation of the De Novo Serine Synthesis Pathway and Disruption of Insulin Signaling Induced by Supplemental SeMet in Vitro: Activation of the De Novo Serine Synthesis Pathway and Disruption of Insulin Signaling Induced by Supplemental SeMet in Vitro

Zhan, Shuo, Huang, Jiaqiang, Liu, Yiqun, Han, Feng, Wang, Jianrong, Wang, Qin^{Aff1, IDs1201102404492y_cor1}, Huang, Zhenwu^{Aff1, Aff3, IDs1201102404492y_cor2}

Garlic-Derived Exosome-Like Nanovesicles: A Promising Natural Nanotherapy for Periodontitis via PHGDH/PI3K/AKT-Mediated Metabolic and Inflammatory Regulation

Yu C, Liu Y, Yu X, Liu J, Cao P, Liu G, Cai Y, Zhang Y, Luan Q

electronic resource

Visa; Visa

Non-canonical function of PHGDH promotes HCC metastasis by interacting with METTL3

Cheng, Bin^Aff1, Ma, Jing^Aff1, Tang, Ni, Liu, Rui, Peng, Pai^{Aff1, IDs13402024010292_cor1}, Wang, Kai^{Aff1, IDs13402024010292_cor2}

Increased Expression of PHGDH Under High-Selenium Stress In Vivo

Wang, Qin, Wang, Jianrong, Zhang, Xue, Liu, Yiqun, Han, Feng, Xiang, Xuesong, Guo, Yanbin, Huang, Zhen-wu^{Aff3, IDs12011024040797_cor8}

PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway

Xiaojin Liu, Bangxin Liu, Junwen Wang, Hongbin Liu, Jiasheng Wu, Yiwei Qi, Yuan Liu, Hongtao Zhu, Chaoxi Li, Liu Yang, Jian Song, Guojie Yao, Weidong Tian, Kai Zhao, Lin Han, Kai Shu, Suojun Zhang, Jianghong Man, Chao You, Haohao Huang, Ran Li

electronic resource

Visa

Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis

Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

electronic resource

Visa

Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway

Gong, Kunxiang^{Aff1, Aff2}, Huang, Yinger, Zheng, Yanqin, Zhu, Yinfu, Hao, Wenbo^{Aff4, IDs12672024010130_cor5}, Shi, Kun^{Aff1, Aff2, IDs12672024010130_cor6}

The cyanobacterial toxins BMAA and 2,4-DAB perturb the l-serine biosynthesis pathway and induce systemic changes in energy metabolism in human neuroblastoma cells: A proteomic study

Pu, Lisa ^a, Steele, Joel R. ^b, Phillips, Connor R. ^a, Violi, Jake P. ^c, Rodgers, Kenneth J. ^{a, ⁎}

L-serine metabolic regulation and host respiratory homeostasis

Pan Li, Xiaoyan Wu, Yanlan Huang, Ruijing Qin, Pan Xiong, Yangyang Qiu

electronic resource

Visa; Visa

SOX12 promotes serine synthesis and tumor progression in endometrial cancer

Zhang, Zi-hui ^{a, b, 1}, Hui, Yan ^{a, b, 1}, Wan, Qiong ^{a, b, 1}, Hu, Xing-yan ^{a, b}, Wang, Hao ^{a, b}, Liu, Cheng-cheng ^{a, b}, Wan, Feng-zhi ^{a, b}, Huang, Chun-yan ^{a, b}, Yi, Feng-xian ^{a, b}, Zeng, Shu-hua ^{a, b}, Li, Shuang ^{a, b, ⁎}, Ye, Hong ^{a, b, ⁎}

Mathematical modelling of carbohydrate and protein metabolism in muscle

Alharbi, Bandar Muidh ^{a, b}, Williams, Hannah E. ^{a, c}, Parr, Tim ^c, Brameld, John M ^c, Fallaize, Christopher ^a, Wattis, Jonathan A.D. ^{a, ⁎}

Molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH

Ziqi Huang, Kun Zhang, Yurui Jiang, Mengmeng Wang, Mei Li, Yuda Guo, Ruolin Gao, Ning Li, Chenyang Wang, Jia Chen, Jiefu Wang, Ning Liu, Xiang Liu, Shuangwei Liu, Mingming Wei, Cheng Yang, Guang Yang

electronic resource

Visa; Visa

Targeting metabolic reprogramming to overcome drug resistance in advanced bladder cancer: insights from gemcitabine‐ and cisplatin‐resistant models

Ichiro Kawahara, Hirofumi Yoshino, Wataru Fukumoto, Junya Arima, Saeki Saito, Gang Li, Ikumi Fukuda, Akihiko Mitsuke, Takashi Sakaguchi, Satoru Inoguchi, Ryosuke Matsushita, Masayuki Nakagawa, Shuichi Tatarano, Yasutoshi Yamada, Hideki Enokida

electronic resource

Visa; Visa

Phosphoglycerate Dehydrogenase Overexpression Inhibits Ferroptosis to Repress Calcification of Human Coronary Artery Vascular Smooth Muscle Cells via the P53/SLC7A11 Pathway

Zou Y, Li D, Guan G, Liu W

electronic resource

Visa; Visa

Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

Cai, Zhengnan^{Aff1, Aff2}, Li, Wan^{Aff1, Aff2}, Hager, Sonja^{Aff3, Aff4}, Wilson, Jayne Louise, Afjehi-Sadat, Leila, Heiss, Elke H., Weichhart, Thomas, Heffeter, Petra, Weckwerth, Wolfram^{Aff1, Aff8, IDs41423024011340_cor1}

KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner

Wang, Xin-Yu, Li, Hong-Ming, Xia, Ran, Li, Xiang, Zhang, Xing, Jin, Tong-Zhao, Zhang, Hong-Sheng^{Aff1, IDs11010023047771_cor7}

Acidosis overrides molecular heterogeneity to shape therapeutically targetable metabolic phenotypes in colon cancers

Richiardone, Elena ^a, Giolito, Maria Virginia ^a, Al Roumi, Rim ^a, Ambroise, Jérôme ^b, Boidot, Romain ^c, Drotleff, Bernhard ^d, Ghesquière, Bart ^{e, f}, Lupo, Barbara ^{g, h}, Trusolino, Livio ^{g, h}, Bardelli, Alberto ^{i, j}, Arena, Sabrina ^{g, h}, Feron, Olivier ^{a, k}, Corbet, Cyril ^{a, k, ⁎}

Ailanthone targets the KMT2A-MEN1 complex to suppress lung metastasis of osteosarcoma

Liang, Jinrong ^{a, b, 1}, Qiao, Guanglei ^{a, 1}, Zhang, Yawen ^{b, 1}, Yuan, Ying ^a, Liu, Zimei ^a, Jiang, Yue ^a, Zhang, Yan ^a, Deng, Zhoufeng ^a, Yu, Liping ^a, Lin, Hongjian ^a, Ma, Lijun ^a, Luo, Yanli ^c, Zhou, Yan ^b, Hu, Haiyan ^{d, ⁎}, Liu, Xin ^{e, f, ⁎}, Zhang, Jianjun ^{a, ⁎}

Chemical Components of the Fruits of Morus nigra Linn.: Methyl Caffeate as a Potential Anticancer Agent by Targeting 3‑Phosphoglycerate Dehydrogenase

Wang, Yali^aff1, Zheng, Mengzhu^aff2, Jiang, Qinghua^aff3, Xu, Yang^aff1, Zhou, Xuechen^aff2, Zhang, Na^aff1, Sun, Dejuan^aff1, Li, Hua^{aff1, aff2}, Chen, Lixia^aff1

Classical swine fever virus inhibits serine metabolism-mediated antiviral immunity by deacetylating modified PHGDH

Xiaowen Li, Yaoyao Huang, Xueyi Liu, Lihong Zhang, Xinyan Wang, Feifan Zhao, Linke Zou, Keke Wu, Wenxian Chen, Yuwei Qin, Sen Zeng, Bingke Li, Yintao He, Yiwan Song, Zhaoyao Li, Jindai Fan, Mingqiu Zhao, Lin Yi, Hongxing Ding, Shuangqi Fan, Jinding Chen

electronic resource

Visa