Sökresultat - "PIWI"

Two-factor authentication underpins the precision of the piRNA pathway.

Dias Mirandela M; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Zoch A; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Leismann J; Institute of Molecular Biology, Mainz, Germany., Webb S; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Berrens RV; IDRM, Department of Paediatrics, University of Oxford, Oxford, UK.; Department of Biochemistry, Oxford University, Oxford, UK., Valsakumar D; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.; Epigenetics Programme, Babraham Institute, Cambridge, UK., Kabayama Y; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Auchynnikava T; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Schito M; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Chowdhury T; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., MacLeod D; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Xiang X; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.; Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, Zhejiang University, Haining, China., Zou J; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Rappsilber J; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.; Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany., Allshire RC; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Voigt P; Epigenetics Programme, Babraham Institute, Cambridge, UK., Cook AG; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK., Barau J; Institute of Molecular Biology, Mainz, Germany., O'Carroll D; Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK. donal.ocarroll@ed.ac.uk.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK. donal.ocarroll@ed.ac.uk.

Journal Article , 2024

The expression profiles of piRNAs and their interacting Piwi proteins in cellular model of renal development: Focus on Piwil1 in mitosis.

Kazimierczyk M; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland., Fedoruk-Wyszomirska A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland., Gurda-Woźna D; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland., Wyszko E; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland., Swiatkowska A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland. Electronic address: agaswiat@ibch.poznan.pl., Wrzesinski J; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland. Electronic address: wrzesinj@ibch.poznan.pl.

Journal Article , 2024

Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.

Li Z; School of Basic Medical Sciences, Fudan University, Shanghai, China.; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Li Z; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Zhang Y; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China., Zhou L; School of Basic Medical Sciences, Fudan University, Shanghai, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China., Xu Q; School of Basic Medical Sciences, Fudan University, Shanghai, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China., Li L; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Zeng L; Department of Computer Science and Engineering, Center for Cognitive Machines and Computational Health (CMaCH), Shanghai Jiao Tong University, Shanghai, China., Xue J; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Niu H; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Zhong J; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Yu Q; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Li D; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China., Gui M; Liangzhu Laboratory, Zhejiang University, Hangzhou, China.; Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China., Huang Y; Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological SciencesChinese Academy of Sciences, Shanghai, China., Tu S; Department of Computer Science and Engineering, Center for Cognitive Machines and Computational Health (CMaCH), Shanghai Jiao Tong University, Shanghai, China., Zhang Z; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Song CQ; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. songchunqing@westlake.edu.cn.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. songchunqing@westlake.edu.cn.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China. songchunqing@westlake.edu.cn., Wu J; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. wujianping@westlake.edu.cn.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China. wujianping@westlake.edu.cn.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. wujianping@westlake.edu.cn., Shen EZ; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. shenenzhi@westlake.edu.cn.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. shenenzhi@westlake.edu.cn.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China. shenenzhi@westlake.edu.cn.

Journal Article , 2024

PiRNA hsa_piR_019914 Promoted Chondrocyte Anabolic Metabolism By Inhibiting LDHA-Dependent ROS Production.

Gao Y; Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, P.R. China., Yan W; Center of Stomatology, The Second Affiliated Hospital of Soochow University, Soochow, P.R. China., Sun L; Department of Orthopedic Surgery, Luan Hospital, Anhui Medical University, Luan, China., Zhang X; Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, P.R. China.; Department of Orthopedics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.

Journal Article , 2024

miRNA and piRNA differential expression profiles in Alzheimer's disease: A potential source of pathology and tool for diagnosis.

Landon B; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, United States of America., Subasinghe K; Department of Microbiology Immunology and Genetics, University of North Texas Health Science Center, Fort Worth, TX 76107, United States of America., Sumien N; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, United States of America., Phillips N; Department of Microbiology Immunology and Genetics, University of North Texas Health Science Center, Fort Worth, TX 76107, United States of America; Institute for Translational Research, University of North Texas Health Science Center, Fort Worth, TX 76107, United States of America. Electronic address: nicole.phillips@unthsc.edu.

Journal Article , 2025

Investigating a role for piRNA-associated piwi genes in overcoming host-plant resistance in the soybean aphid, Aphis glycines.

Haller A; Department of Entomology, The Ohio State University, Wooster, OH, USA., Poelstra JW; Molecular and Cellular Imaging Center, The Ohio State University, Wooster, OH, USA., Pipatpongpinyo W; Molecular and Cellular Imaging Center, The Ohio State University, Wooster, OH, USA., Kreuter N; Department of Entomology, The Ohio State University, Wooster, OH, USA.; Department of Biological Sciences, The College of Wooster, Wooster, OH, USA., Wilson JR; USDA Agricultural Research Service, Corn, Soybean & Wheat Quality Research Unit, Wooster, OH, USA., Michel A; Department of Entomology, The Ohio State University, Wooster, OH, USA.

Journal Article , 2025

Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development.

Lee SK; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Shen W; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Wen W; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Joo Y; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Xue Y; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Park A; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Qiang A; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Su S; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Zhang T; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Zhang M; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Fan J; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Zhang Y; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., De S; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Gainetdinov I; Department of Biology, New York University, New York, NY 10003, USA., Sharov A; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Maragkakis M; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Wang W; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address: wangw@grc.nia.nih.gov.

Journal Article , 2025

Potentially diagnostic and prognostic roles of piRNAs/PIWIs in pancreatic cancer: A review.

Liu Y; Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Li C; Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Cui X; Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Li M; Prenatal Diagnosis Center, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China., Liu S; Prenatal Diagnosis Center, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China. Electronic address: liushiguo@qdu.edu.cn., Wang Z; Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: wangzusen@126.com.

Journal Article; Review , 2025

Identifying piRNAs that regulate BaP-induced lung injuries: A bottom-up approach from toxicity pathway investigation to animal validation.

Lei Q; School of Public Health, Qingdao University, Qingdao, China., Du C; School of Public Health, Qingdao University, Qingdao, China., Ma Y; School of Public Health, Qingdao University, Qingdao, China., Shou Y; School of Public Health, Qingdao University, Qingdao, China., Chen L; School of Public Health, Qingdao University, Qingdao, China., Feng C; School of Public Health, Qingdao University, Qingdao, China., Zheng Y; School of Public Health, Qingdao University, Qingdao, China., Yu D; School of Public Health, Qingdao University, Qingdao, China., Jin Y; School of Public Health, Qingdao University, Qingdao, China. Electronic address: yuanjin@qdu.edu.cn.

Journal Article , 2024

Identification and expression patterns of somatic piRNAs and PIWI genes in Riptortus pedestris (Hemiptera: Alydidae).

Ren Y; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin, P.R. China., Dong W; Tianjin Key Laboratory of Food and Biotechnology, School of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin, P.R. China., Bu W; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin, P.R. China., Xue H; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin, P.R. China.

Journal Article , 2024

piRNA processing within non-membrane structures is governed by constituent proteins and their functional motifs.

Suyama R; Laboratory of Germline Biology, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan., Kai T; Laboratory of Germline Biology, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.

Journal Article; Review , 2025

Sex-biased fertility degeneration induced by depletion of an auxiliary piRNA-pathway factor Qin in Bombyx mori.

Chen K; Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Scientific Research Center, Chinese Academy of Agricultural Sciences, Zhenjiang, 212100, China., Ye L; Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Scientific Research Center, Chinese Academy of Agricultural Sciences, Zhenjiang, 212100, China., Yu Y; Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Scientific Research Center, Chinese Academy of Agricultural Sciences, Zhenjiang, 212100, China., Guo P; Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Scientific Research Center, Chinese Academy of Agricultural Sciences, Zhenjiang, 212100, China., Tan A; Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture and Rural Affairs, Sericultural Scientific Research Center, Chinese Academy of Agricultural Sciences, Zhenjiang, 212100, China. Electronic address: atan@just.edu.cn.

Journal Article , 2025

iPiDA-LGE: a local and global graph ensemble learning framework for identifying piRNA-disease associations.

Wei H; School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, 710126, China. weihang@xidian.edu.cn., Hou J; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China., Liu Y; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, Guangdong, 518118, China., Shaytan AK; Department of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.; International Laboratory of Bioinformatics, AI and Digital Sciences Institute, Faculty of Computer Science, HSE University, Moscow, 109028, Russia., Liu B; SMBU-MSU-BIT Joint Laboratory On Bioinformatics and Engineering Biology, Shenzhen MSU-BIT University, Shenzhen, Guangdong, 518172, China. bliu@bliulab.net.; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China. bliu@bliulab.net.; Zhongguancun Academy, Beijing, 100094, China. bliu@bliulab.net., Wu H; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China. hwu@bliulab.net.

Journal Article , 2025

Evolution of piRNA-guided defense against transposable elements.

Pritam S; Biological Sciences, North Dakota State University, Fargo, ND, USA., Signor S; Biological Sciences, North Dakota State University, Fargo, ND, USA. Electronic address: sarah.signor@ndsu.edu.

Journal Article; Review , 2025

Integration of multi-omics data to unveil the molecular landscape and role of piRNAs in early-onset colorectal cancer.

Zhou S; Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Yu L; Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Zhao J; Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Xiao Q; Department of Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China., Sun J; Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Wang L; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Zhou Y; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Lu Y; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Dunlop MG; Cancer Research UK Scotland Centre and Medical Research Council Human Genetics Unit, University of Edinburgh, Edinburgh, UK., Theodoratou E; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.; Cancer Research UK Scotland Centre and Medical Research Council Human Genetics Unit, University of Edinburgh, Edinburgh, UK., Zhang H; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. honghezhang@zju.edu.cn., Ding K; Department of Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China. dingkefeng@zju.edu.cn.; Center for Medical Research and Innovation in Digestive System Tumors, Ministry of Education, Hangzhou, China. dingkefeng@zju.edu.cn.; Zhejiang Provincial Clinical Research Center for CANCER, Hangzhou, China. dingkefeng@zju.edu.cn., Li X; Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. xueli157@zju.edu.cn.

Journal Article , 2025

Paramutation-Like Behavior of Genic piRNA-Producing Loci in Drosophila virilis .

Bespalova AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Kulikova DA; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia., Zelentsova ES; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Rezvykh AP; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Guseva IO; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Moscow Center for Advanced Studies, Kulakova Str. 20, 123592 Moscow, Russia., Dorador AP; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Funikov SY; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

Journal Article , 2025

Traffic Jam activates the Flamenco piRNA cluster locus and the Piwi pathway to ensure transposon silencing and Drosophila fertility.

Rivera AJ; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Lee JR; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Gupta S; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Yang L; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Goel RK; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA; Proteomics Service Center and Center for Network Systems Biology, Boston University, Boston, MA, USA., Zaia J; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA; Proteomics Service Center and Center for Network Systems Biology, Boston University, Boston, MA, USA., Lau NC; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA; Genome Science Institute, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA. Electronic address: nclau@bu.edu.

Journal Article , 2025

The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries.

Alizada A; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK., Martins A; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Mouniée N; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Rodriguez Suarez JV; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK., Bertin B; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Gueguen N; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Mirouse V; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Papameletiou AM; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK., Rivera AJ; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Lau NC; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Akkouche A; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Maupetit-Méhouas S; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France., Hannon GJ; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK. Electronic address: greg.hannon@cruk.cam.ac.uk., Czech Nicholson B; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK. Electronic address: ben.nicholson@cruk.cam.ac.uk., Brasset E; iGReD, Université Clermont Auvergne, CNRS, INSERM, Faculté de Médecine, 63000 Clermont-Ferrand, France. Electronic address: emilie.brasset@uca.fr.

Journal Article , 2025

A catalytic hairpin assembly system with sliding replication for the detection of piRNAs.

Yang H; Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China. zhongxw31@nsmc.edu.cn.; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Gong F; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Yao C; Department of Geriatrics, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Cheng J; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., He S; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Jia Y; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Zhang Y; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China., Ma Q; Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China. zhongxw31@nsmc.edu.cn., Guo X; Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China. zhongxw31@nsmc.edu.cn., He H; Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China. zhongxw31@nsmc.edu.cn., Zhong X; Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan, China. zhongxw31@nsmc.edu.cn.; School of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000 Sichuan, China.; Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000 Sichuan, China.

Journal Article , 2025

In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins.

Kawaguchi S; Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan., Xu X; Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan., Soga T; D3 Center, Osaka University, Osaka, Japan., Yamaguchi K; NEC Solution Innovators, Ltd., Tokyo, Japan., Kawasaki R; NEC Solution Innovators, Ltd., Tokyo, Japan., Shimouchi R; Graduate School of Information Science and Technology, Osaka University, Osaka, Japan., Date S; D3 Center, Osaka University, Osaka, Japan.; Graduate School of Information Science and Technology, Osaka University, Osaka, Japan., Kai T; Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.

Journal Article , 2025