Sökresultat - "Pengrong Yan"

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation

Tanaya Roychowdhury, Seth W. McNutt, Chiranjeevi Pasala, Hieu T. Nguyen, Daniel T. Thornton, Sahil Sharma, Luke Botticelli, Chander S. Digwal, Suhasini Joshi, Nan Yang, Palak Panchal, Souparna Chakrabarty, Sadik Bay, Vladimir Markov, Charlene Kwong, Jeanine Lisanti, Sun Young Chung, Stephen D. Ginsberg, Pengrong Yan, Elisa De Stanchina, Adriana Corben, Shanu Modi, Mary L. Alpaugh, Giorgio Colombo, Hediye Erdjument-Bromage, Thomas A. Neubert, Robert J. Chalkley, Peter R. Baker, Alma L. Burlingame, Anna Rodina, Gabriela Chiosis, Feixia Chu

electronic resource

Visa

Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2

Fan Sun, Pengrong Yan, Yadong Xiao, Hongqiao Zhang, Steven D Shapiro, Gutian Xiao, Zhaoxia Qu

electronic resource

Visa; Visa

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

Anna Rodina, Chao Xu, Chander S. Digwal, Suhasini Joshi, Yogita Patel, Anand R. Santhaseela, Sadik Bay, Swathi Merugu, Aftab Alam, Pengrong Yan, Chenghua Yang, Tanaya Roychowdhury, Palak Panchal, Liza Shrestha, Yanlong Kang, Sahil Sharma, Justina Almodovar, Adriana Corben, Mary L. Alpaugh, Shanu Modi, Monica L. Guzman, Teng Fei, Tony Taldone, Stephen D. Ginsberg, Hediye Erdjument-Bromage, Thomas A. Neubert, Katia Manova-Todorova, Meng-Fu Bryan Tsou, Jason C. Young, Tai Wang, Gabriela Chiosis

electronic resource

Visa

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

Suhasini Joshi, Erica DaGama Gomes, Tai Wang, Adriana Corben, Tony Taldone, Srinivasa Gandu, Chao Xu, Sahil Sharma, Salma Buddaseth, Pengrong Yan, Lon Yin L. Chan, Askan Gokce, Vinagolu K. Rajasekhar, Lisa Shrestha, Palak Panchal, Justina Almodovar, Chander S. Digwal, Anna Rodina, Swathi Merugu, NagaVaraKishore Pillarsetty, Vlad Miclea, Radu I. Peter, Wanyan Wang, Stephen D. Ginsberg, Laura Tang, Marissa Mattar, Elisa de Stanchina, Kenneth H. Yu, Maeve Lowery, Olivera Grbovic-Huezo, Eileen M. O’Reilly, Yelena Janjigian, John H. Healey, William R. Jarnagin, Peter J. Allen, Chris Sander, Hediye Erdjument-Bromage, Thomas A. Neubert, Steven D. Leach, Gabriela Chiosis

electronic resource

Visa

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Alexander Bolaender, Danuta Zatorska, Huazhong He, Suhasini Joshi, Sahil Sharma, Chander S. Digwal, Hardik J. Patel, Weilin Sun, Brandon S. Imber, Stefan O. Ochiana, Maulik R. Patel, Liza Shrestha, Smit. K. Shah, Shuo Wang, Rashad Karimov, Hui Tao, Pallav D. Patel, Ananda Rodilla Martin, Pengrong Yan, Palak Panchal, Justina Almodovar, Adriana Corben, Andreas Rimner, Stephen D. Ginsberg, Serge Lyashchenko, Eva Burnazi, Anson Ku, Teja Kalidindi, Sang Gyu Lee, Milan Grkovski, Bradley J. Beattie, Pat Zanzonico, Jason S. Lewis, Steve Larson, Anna Rodina, Nagavarakishore Pillarsetty, Viviane Tabar, Mark P. Dunphy, Tony Taldone, Fumiko Shimizu, Gabriela Chiosis

electronic resource

Visa

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

Maria Carmen Inda, Suhasini Joshi, Tai Wang, Alexander Bolaender, Srinivasa Gandu, John Koren III, Alicia Yue Che, Tony Taldone, Pengrong Yan, Weilin Sun, Mohammad Uddin, Palak Panchal, Matthew Riolo, Smit Shah, Afsar Barlas, Ke Xu, Lon Yin L. Chan, Alexandra Gruzinova, Sarah Kishinevsky, Lorenz Studer, Valentina Fossati, Scott A. Noggle, Julie R. White, Elisa de Stanchina, Sonia Sequeira, Kyle H. Anthoney, John W. Steele, Katia Manova-Todorova, Sujata Patil, Mark P. Dunphy, NagaVaraKishore Pillarsetty, Ana C. Pereira, Hediye Erdjument-Bromage, Thomas A. Neubert, Anna Rodina, Stephen D. Ginsberg, Natalia De Marco Garcia, Wenjie Luo, Gabriela Chiosis

electronic resource

Visa

Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

Fan Sun, Liwen Li, Pengrong Yan, Jingjiao Zhou, Steven D. Shapiro, Gutian Xiao, Zhaoxia Qu

electronic resource

Visa

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

Pengrong Yan, Hardik J. Patel, Sahil Sharma, Adriana Corben, Tai Wang, Palak Panchal, Chenghua Yang, Weilin Sun, Thais L. Araujo, Anna Rodina, Suhasini Joshi, Kenneth Robzyk, Srinivasa Gandu, Julie R. White, Elisa de Stanchina, Shanu Modi, Yelena Y. Janjigian, Elizabeth G. Hill, Bei Liu, Hediye Erdjument-Bromage, Thomas A. Neubert, Nanette L.S. Que, Zihai Li, Daniel T. Gewirth, Tony Taldone, Gabriela Chiosis

electronic resource

Visa; Visa

Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Pengrong Yan, Zhaoxia Qu, Chie Ishikawa, Naoki Mori, Gutian Xiao

electronic resource

Visa; Visa; Visa

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The epichaperome is an integrated chaperome network that facilitates tumour survival.

Rodina, Anna, Tai Wang, Pengrong Yan, DaGama Gomes, Erica, Dunphy, Mark P. S., Pillarsetty, Nagavarakishore, Koren III, John, Gerecitano, John F., Taldone, Tony, Hongliang Zong, Caldas-Lopes, Eloisi, Alpaugh, Mary, Corben, Adriana, Riolo, Matthew, Beattie, Brad, Pressl, Christina, Peter, Radu I., Chao Xu, Trondl, Robert, Patel, Hardik J.

Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation.

Guoliang Qing, Pengrong Yan, Zhaoxia Qu, Hudan Liu, Gutian Xiao

Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK).

Guoliang Qing, Pengrong Yan, Gutian Xiao

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Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Taxmediated tumorigenesis.

Jing Fu, Zhaoxia Qu, Pengrong Yan, Shirong Li, Xinxin Song, Chie Ishikawa, Aqeilan, Rami I., Mori, Naoki, Rabson, Arnold B., Gutian Xiao

Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.

Yifeng Li^1,2, Dandan Zhang¹, Wei Jin^2,3, Chunhong Shao⁴, Pengrong Yan¹, Congjian Xu⁵, Haihui Sheng², Yan Liu^2,3, Jinde Yu³, Yuying Xie¹, Yingnan Zhao¹, Lu, Daru¹, Nebert, Daniel W.⁶, Harrison, Donald C.⁶, Wei Huang^2,3 huangwei@chgc.sh.cn, Jin, Li^1,6 ljin007@gmail.com