Search Results - "Peter D Kwong"

Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.

Li Ou, Steven J Chen, I-Ting Teng, Lijuan Yang, Baoshan Zhang, Tongqing Zhou, Andrea Biju, Cheng Cheng, Wing-Pui Kong, Nicholas C Morano, Erik-Stephane D Stancofski, John-Paul Todd, Yaroslav Tsybovsky, Shuishu Wang, Cheng-Yan Zheng, John R Mascola, Lawrence Shapiro, Ruth A Woodward, Ursula J Buchholz, Peter D Kwong

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Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.

Hugh C Welles, Hannah A D King, Leonard Nettey, Nicole Cavett, Jason Gorman, Tongqing Zhou, Yaroslav Tsybovsky, Renguang Du, Kaimei Song, Richard Nguyen, David Ambrozak, Amy Ransier, Chaim A Schramm, Nicole A Doria-Rose, Adrienne E Swanstrom, James A Hoxie, Celia LaBranche, David C Montefiori, Daniel C Douek, Peter D Kwong, John R Mascola, Mario Roederer, Rosemarie D Mason

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Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.

I-Ting Teng, Alexandra F Nazzari, Misook Choe, Tracy Liu, Matheus Oliveira de Souza, Yuliya Petrova, Yaroslav Tsybovsky, Shuishu Wang, Baoshan Zhang, Mykhaylo Artamonov, Bharat Madan, Aric Huang, Sheila N Lopez Acevedo, Xiaoli Pan, Tracy J Ruckwardt, Brandon J DeKosky, John R Mascola, John Misasi, Nancy J Sullivan, Tongqing Zhou, Peter D Kwong

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High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19.

Sung Hee Ko, Elham Bayat Mokhtari, Prakriti Mudvari, Sydney Stein, Christopher D Stringham, Danielle Wagner, Sabrina Ramelli, Marcos J Ramos-Benitez, Jeffrey R Strich, Richard T Davey, Tongqing Zhou, John Misasi, Peter D Kwong, Daniel S Chertow, Nancy J Sullivan, Eli A Boritz

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Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans.

Zhaochun Chen, Ronald E Engle, Chen-Hsiang Shen, Huaying Zhao, Peter W Schuck, Emily J Danoff, Hanh Nguyen, Norihisa Nishimura, Kevin W Bock, Ian N Moore, Peter D Kwong, Robert H Purcell, Sugantha Govindarajan, Patrizia Farci

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Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates.

Xueqiao Liu, Bo Liang, Xiang Liu, Emerito Amaro-Carambot, Sonja Surman, Peter D Kwong, Barney S Graham, Peter L Collins, Shirin Munir

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Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.

Celia C LaBranche, Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, Kevin O Saunders, S Munir Alam, Mattia Bonsignori, Mario J Borgnia, Quentin J Sattentau, Amanda Eaton, Kelli Greene, Hongmei Gao, Hua-Xin Liao, Wilton B Williams, James Peacock, Haili Tang, Lautaro G Perez, Robert J Edwards, Thomas B Kepler, Bette T Korber, Peter D Kwong, John R Mascola, Priyamvada Acharya, Barton F Haynes, David C Montefiori

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Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.

Celia C LaBranche, Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, Kevin O Saunders, S Munir Alam, Mattia Bonsignori, Mario J Borgnia, Quentin J Sattentau, Amanda Eaton, Kelli Greene, Hongmei Gao, Hua-Xin Liao, Wilton B Williams, James Peacock, Haili Tang, Lautaro G Perez, Robert J Edwards, Thomas B Kepler, Bette T Korber, Peter D Kwong, John R Mascola, Priyamvada Acharya, Barton F Haynes, David C Montefiori

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Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage.

David Sacks, Jinal N Bhiman, Kevin Wiehe, Jason Gorman, Peter D Kwong, Lynn Morris, Penny L Moore

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Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.

Sean P O'Brien, Adrienne E Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T Immonen, Gregory Q Del Prete, Christine M Fennessey, Jason Gorman, Kathryn E Foulds, Stephen D Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D Bieniasz, Hui Li, George M Shaw, John R Mascola, Richard A Koup, Peter D Kwong, Jeffrey D Lifson, Mario Roederer, Brandon F Keele

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Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

Celia C LaBranche, Andrew T McGuire, Matthew D Gray, Shay Behrens, Xuejun Chen, Tongqing Zhou, Quentin J Sattentau, James Peacock, Amanda Eaton, Kelli Greene, Hongmei Gao, Haili Tang, Lautaro G Perez, Kevin O Saunders, Peter D Kwong, John R Mascola, Barton F Haynes, Leonidas Stamatatos, David C Montefiori

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HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

Celia C LaBranche, Andrew T McGuire, Matthew D Gray, Shay Behrens, Peter D Kwong, Xuejun Chen, Tongqing Zhou, Quentin J Sattentau, James Peacock, Amanda Eaton, Kelli Greene, Hongmei Gao, Haili Tang, Lautaro G Perez, Kevin O Saunders, John R Mascola, Barton F Haynes, Leonidas Stamatatos, David C Montefiori

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Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

Andrew J Borst, Connor E Weidle, Matthew D Gray, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume BE Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler

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Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.

Adam S Dingens, Priyamvada Acharya, Hugh K Haddox, Reda Rawi, Kai Xu, Gwo-Yu Chuang, Hui Wei, Baoshan Zhang, John R Mascola, Bridget Carragher, Clinton S Potter, Julie Overbaugh, Peter D Kwong, Jesse D Bloom

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Routine single particle CryoEM sample and grid characterization by tomography

Alex J Noble, Venkata P Dandey, Hui Wei, Julia Brasch, Jillian Chase, Priyamvada Acharya, Yong Zi Tan, Zhening Zhang, Laura Y Kim, Giovanna Scapin, Micah Rapp, Edward T Eng, William J Rice, Anchi Cheng, Carl J Negro, Lawrence Shapiro, Peter D Kwong, David Jeruzalmi, Amedee des Georges, Clinton S Potter, Bridget Carragher

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HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

Xiaochu Ma, Maolin Lu, Jason Gorman, Daniel S Terry, Xinyu Hong, Zhou Zhou, Hong Zhao, Roger B Altman, James Arthos, Scott C Blanchard, Peter D Kwong, James B Munro, Walther Mothes

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Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

Nuria González, Krisha McKee, Rebecca M Lynch, Ivelin S Georgiev, Laura Jimenez, Eulalia Grau, Eloísa Yuste, Peter D Kwong, John R Mascola, José Alcamí

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Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus.

Mallika Sastry, Baoshan Zhang, Man Chen, M Gordon Joyce, Wing-Pui Kong, Gwo-Yu Chuang, Kiyoon Ko, Azad Kumar, Chiara Silacci, Michelle Thom, Andres M Salazar, Davide Corti, Antonio Lanzavecchia, Geraldine Taylor, John R Mascola, Barney S Graham, Peter D Kwong

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Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.

Nicole A Doria-Rose, Han R Altae-Tran, Ryan S Roark, Stephen D Schmidt, Matthew S Sutton, Mark K Louder, Gwo-Yu Chuang, Robert T Bailer, Valerie Cortez, Rui Kong, Krisha McKee, Sijy O'Dell, Felicia Wang, Salim S Abdool Karim, James M Binley, Mark Connors, Barton F Haynes, Malcolm A Martin, David C Montefiori, Lynn Morris, Julie Overbaugh, Peter D Kwong, John R Mascola, Ivelin S Georgiev

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Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

Constantinos Kurt Wibmer, Jason Gorman, Gabriel Ozorowski, Jinal N Bhiman, Daniel J Sheward, Debra H Elliott, Julie Rouelle, Ashley Smira, M Gordon Joyce, Nonkululeko Ndabambi, Aliaksandr Druz, Mangai Asokan, Dennis R Burton, Mark Connors, Salim S Abdool Karim, John R Mascola, James E Robinson, Andrew B Ward, Carolyn Williamson, Peter D Kwong, Lynn Morris, Penny L Moore

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