Search Results - "Piatnitski Chekler, Eugene L."

Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6‑Bromoisoquinoline-1-carbonitrile with (S)‑3-Amino-2-methylpropan-1-ol

Sperry, Jeffrey B.^aff1, Price Wiglesworth, Kristin E.^aff1, Edmonds, Ian^aff2, Fiore, Phillip^aff2, Boyles, David C.^aff1, Damon, David B.^aff1, Dorow, Roberta L.^aff1, Piatnitski Chekler, Eugene L.^aff3, Langille, Jonathan^aff3, Coe, Jotham W.^aff3

Electrostatic Docking of a Supramolecular Host−Guest Assembly to Cytochrome c Probed by Bidirectional Photoinduced Electron Transfer
Docking of a Supramolecular Host−Guest Assembly to Cytochrome c

Jankowska, Katarzyna I., Pagba, Cynthia V., Piatnitski Chekler, Eugene L., Deshayes, Kurt, Piotrowiak, Piotr

Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2

Duncton, Matthew A.J., Piatnitski Chekler, Eugene L., Katoch-Rouse, Reeti, Sherman, Dan, Wong, Wai C., Smith, Leon M., II, Kawakami, Joel K., Kiselyov, Alexander S., Milligan, Daniel L., Balagtas, Chris, Hadari, Yaron R., Wang, Ying, Patel, Sheetal N., Rolster, Robin L., Tonra, James R., Surguladze, David, Mitelman, Stan, Kussie, Paul, Bohlen, Peter, Doody, Jacqueline F.

Azaindolines: derisking the indoline structural alert

Piatnitski Chekler, Eugene L., Khan, Taukeer A., Mamidala, Rajanikanth, Anderson, James T., Tangirala, Raghuram S., Verhoest, Patrick R., Gilbert, Adam M.

Structure-Based Design of Highly Selective Inhibitors of the CREB Binding Protein Bromodomain.

Denny, R. Aldrin¹ aldin.denny@pfizer.com, Flick, Andrew C.², Coe, Jotham², Langille, Jonathan², Basak, Arindrajit², Shenping Liu³, Stock, Ingrid⁴, Sahasrabudhe, Parag³, Bonin, Paul⁴, Hay, Duncan A.^5,6, Brennan, Paul E.⁶, Pletcher, Mathew⁷, Jones, Lyn H.¹ lynhowardjones@gmail.com, Piatnitski Chekler, Eugene L.¹ piatnits@gmail.com

Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents

Piatnitski Chekler, Eugene L., Butera, John A., Di, Li, Swillo, Robert E., Morgan, Gwen A., Rossman, Eric I., Huselton, Christine, Larsen, Bjarne D., Hennan, James K.

Design and chemical synthesis of [1,2,4]triazol[1,5- c]pyrimidin-5-yl amines, a novel class of VEGFR-2 kinase inhibitors

Kiselyov, Alexander S., Piatnitski Chekler, Eugene L., Chernisheva, Natalia B., Salamandra, Lev K., Semenov, Victor V.

Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors

Piatnitski Chekler, Eugene L., Katoch-Rouse, Reeti, Kiselyov, Alexander S., Sherman, Dan, Ouyang, Xiaohu, Kim, Ki, Wang, Ying, Hadari, Yaron R., Doody, Jacqueline F.

Efficient one-pot synthesis of substituted 2-amino-1,3,4-oxadiazoles

Piatnitski Chekler, Eugene L., Elokdah, Hassan M., Butera, John

Direct photocapture of bromodomains using tropolone chemical probes.

Hett, Erik C., Piatnitski Chekler, Eugene L., Basak, Arindrajit, Bonin, Paul D., Denny, R. Aldrin, Flick, Andrew C., Geoghegan, Kieran F., Liu, Shenping, Pletcher, Mathew T., Sahasrabudhe, Parag, Salter, Shores C., Stock, Ingrid A., Taylor, Alexandria P., Jones, Lyn H.

KiloscaleBuchwald–Hartwig Amination: OptimizedCoupling of Base-Sensitive 6-Bromoisoquinoline-1-carbonitrilewith (S)-3-Amino-2-methylpropan-1-ol.

Sperry, Jeffrey B.¹, Price Wiglesworth, Kristin E.¹, Edmonds, Ian¹, Fiore, Phillip¹, Boyles, David C.¹, Damon, David B.¹, Dorow, Roberta L.¹, Piatnitski Chekler, Eugene L.¹, Langille, Jonathan¹, Coe, Jotham W.¹

Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo.

Kilbourne, Edward J., Kenney, Thomas, Chippari, Susan, McNally, Christopher, Wang, Yihe, Lam, Ho-Sun, Vishwanathan, Karthick, Nagpal, Sunil, Thompson, Catherine C., Piatnitski Chekler, Eugene L.

Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin.

Nabhan, Joseph F., Gooch, Renea L., Piatnitski Chekler, Eugene L., Pierce, Betsy, Bulawa, Christine E.

1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators.

Piatnitski Chekler EL; BioTherapeutics Medicinal Chemistry, Pfizer Global Research and Development , 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Unwalla R, Khan TA, Tangirala RS, Johnson M, St Andre M, Anderson JT, Kenney T, Chiparri S, McNally C, Kilbourne E, Thompson C, Nagpal S, Weber G, Schelling S, Owens J, Morris CA, Powell D, Verhoest PR, Gilbert AM

Journal Article , 2014