Search Results - "Piatnitski Chekler EL"

Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin.

Nabhan JF; Rare Disease Research Unit, Worldwide Research and Development, Pfizer, 610 Main Street, Cambridge, MA 02139, USA., Gooch RL; Rare Disease Research Unit, Worldwide Research and Development, Pfizer, 610 Main Street, Cambridge, MA 02139, USA., Piatnitski Chekler EL; Worldwide Medicinal Chemistry, Pfizer, 610 Main Street, Cambridge, MA 02139, USA., Pierce B; Worldwide Medicinal Chemistry, Pfizer, Eastern Point Road, Groton, CT 06340, USA., Bulawa CE; Rare Disease Research Unit, Worldwide Research and Development, Pfizer, 610 Main Street, Cambridge, MA 02139, USA.

Journal Article , 2015

1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators.

Piatnitski Chekler EL; BioTherapeutics Medicinal Chemistry, Pfizer Global Research and Development , 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Unwalla R, Khan TA, Tangirala RS, Johnson M, St Andre M, Anderson JT, Kenney T, Chiparri S, McNally C, Kilbourne E, Thompson C, Nagpal S, Weber G, Schelling S, Owens J, Morris CA, Powell D, Verhoest PR, Gilbert AM

Journal Article , 2014

Electrostatic docking of a supramolecular host-guest assembly to cytochrome c probed by bidirectional photoinduced electron transfer.

Jankowska KI; Department of Chemistry, Rutgers University, 73 Warren Street, Newark, New Jersey 07102, United States., Pagba CV, Piatnitski Chekler EL, Deshayes K, Piotrowiak P

Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. , 2010

Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents.

Piatnitski Chekler EL; Wyeth Research, Chemical Sciences, Collegeville, PA 19426, USA. piatnits@gmail.com, Butera JA, Di L, Swillo RE, Morgan GA, Rossman EI, Huselton C, Larsen BD, Hennan JK

Journal Article , 2009

Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2.

Duncton MA; ImClone Systems, Inc., 180 Varick Street, New York, NY 10014, USA. mattduncton@yahoo.com, Piatnitski Chekler EL, Katoch-Rouse R, Sherman D, Wong WC, Smith LM 2nd, Kawakami JK, Kiselyov AS, Milligan DL, Balagtas C, Hadari YR, Wang Y, Patel SN, Rolster RL, Tonra JR, Surguladze D, Mitelman S, Kussie P, Bohlen P, Doody JF

Journal Article , 2009

Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors.

Piatnitski Chekler EL; Department of Chemistry, ImClone Systems Incorporated, New York, NY 10014, USA. piatnits@gmail.com, Katoch-Rouse R, Kiselyov AS, Sherman D, Ouyang X, Kim K, Wang Y, Hadari YR, Doody JF

Journal Article , 2008