Search Results - "Pleiotropy"

Characterizing pleiotropy among bipolar disorder, schizophrenia, and major depression: a genome-wide cross-disorder meta-analysis.

Friligkou E; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; Aristotle University of Thessaloniki, Thessaloniki, Greece., Pathak GA; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA., Tylee DS; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA., De Lillo A; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy., Koller D; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA.; Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain., Cabrera-Mendoza B; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA., Polimanti R; Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA.

Journal Article; Meta-Analysis , 2025

A multivariable cis-Mendelian randomization method robust to weak instrument bias and horizontal pleiotropy bias.

Yang Y; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, United States., Lorincz-Comi N; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, United States., Li M; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, United States., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, United States.

Journal Article , 2025

Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation.

Lai WY; Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria.; Vienna Graduate School of Population Genetics, Vetmeduni Vienna, Vienna, Austria., Hsu SK; Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria.; Vienna Graduate School of Population Genetics, Vetmeduni Vienna, Vienna, Austria., Futschik A; Department of Applied Statistics, Johannes Kepler University Linz, Linz, Austria., Schlötterer C; Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria.

Journal Article , 2025

Genetic geroscience and Alzheimer's disease: The pleiotropy is the point!

Shardell M; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Chen C; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD, USA.

Journal Article , 2025

Quantifying pleiotropy through directed signaling networks: A synchronous Boolean network approach and in-silico pleiotropic scoring.

Fareed MM; School of Science and Engineering, Department of Computer Science, Università degli studi di Verona, Verona, Italy. Electronic address: m.mazharfareed97@gmail.com., Shityakov S; Laboratory of Chemoinformatics, Infochemistry Scientific Center, ITMO University, Saint Petersburg, Russia. Electronic address: shityakoff@hotmail.com.

Journal Article , 2025

The role of the brain-bone axis in skeletal degenerative diseases and psychiatric disorders, A genome-wide pleiotropic analysis.

Gao S; The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, China., Qi L; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology, China., Li N; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, China., Li X; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, China., Zhang J; The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, China., Zhang Z; The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, China., Liu W; Shandong University of Traditional Chinese Medicine, China; The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, China. Electronic address: fansui20192020@126.com.

Journal Article; Review , 2025

Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East Asians.

Zhi L; Department of Allergy, Shandong Institute of Respiratory Diseases, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China., Zheng Q; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China., Jiang Y; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Yu L; Institute of infection and immunity, Medical Science and Technology Innovation Center, Shandong First Medical University, Jinan, Shandong, China., Li L; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Song Y; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Peng B; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Zhang C; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Jiang H; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China., Li R; School of Basic Medical Sciences, Shandong First Medical University, Jinan, Shandong, China., Mentch F; The Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Glessner J; The Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Jia P; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China., Tang H; Institute of infection and immunity, Medical Science and Technology Innovation Center, Shandong First Medical University, Jinan, Shandong, China. tanghuazhang218@163.com.; Department of Rheumatology and Autoimmunology, Shandong Provincial Key Laboratory for Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China. tanghuazhang218@163.com., Hakonarson H; The Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Hakonarson@chop.edu., Chang X; Department of Allergy, Shandong Institute of Respiratory Diseases, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China. changxiao@sdfmu.edu.cn.; College of Medical Information and Artificial Intelligence, Shandong First Medical University, Jinan, Shandong, China. changxiao@sdfmu.edu.cn.; The Department of Otorhinolaryngology Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong, China. changxiao@sdfmu.edu.cn.

Journal Article , 2025

Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers.

van der Meer D; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway. d.van.der.meer@medisin.uio.no., Rahman Z; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Ottas A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, 51010, Estonia., Parekh P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Kutrolli G; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Stinson SE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Koromina M; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Rokicki J; Centre of Research and Education in Forensic Psychiatry (SIFER), Oslo University Hospital, Oslo, Norway., Sønderby IE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway., Parker N; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Tesfaye M; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Hindley G; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Psychosis Studies, Institute of Psychiatry, Psychology and Neurosciences, King's College London, London, UK., Rødevand LN; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Koch E; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Steen NE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway., Berg JP; Department of Medical Biochemistry, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., O'Connell KS; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Smeland OB; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Frei O; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Centre for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway., Dale AM; Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA, 92037, USA., Djurovic S; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Lehto K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, 51010, Estonia., Alver M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, 51010, Estonia., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, 51010, Estonia., Shadrin AA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway., Andreassen OA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway. ole.andreassen@medisin.uio.no.; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. ole.andreassen@medisin.uio.no.

Estonian Biobank Research Team

Journal Article , 2025

Pleiotropic effects of barley BLADE-ON-PETIOLE gene Uniculme4 on plant architecture and the jasmonic acid pathway.

Tavakol E; Department of Plant Genetics and Production, Shiraz University, Shiraz, Iran., Shariati V; Department of Molecular Biotechnology, National institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran., Fontana IM; Dipartimento di Scienze Agrarie e Ambientali-Produzione, Territorio, Agroenergia (DiSAA), University of Milan, Via Celoria 2, 20133 Milan, Italy.; Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, D06120 Halle (Saale), Germany., Binaghi M; Dipartimento di Scienze Agrarie e Ambientali-Produzione, Territorio, Agroenergia (DiSAA), University of Milan, Via Celoria 2, 20133 Milan, Italy., Stellmach H; Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, D06120 Halle (Saale), Germany., Hause B; Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, D06120 Halle (Saale), Germany., Bethke G; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Bilgic H; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Boddu J; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Okagaki R; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Heinen S; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Muehlbauer GJ; Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, MN 55108, USA., Rossini L; Dipartimento di Scienze Agrarie e Ambientali-Produzione, Territorio, Agroenergia (DiSAA), University of Milan, Via Celoria 2, 20133 Milan, Italy.

Journal Article , 2025

Multitrait Genetic Analysis Identifies Novel Pleiotropic Loci for Depression and Schizophrenia in East Asians.

Song Y; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Li L; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Jiang Y; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Peng B; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Jiang H; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Chao Z; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China., Chang X; College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University, Shandong, China.

Journal Article , 2025

Identifying links between cardiovascular disease and insomnia by modeling genes from a pleiotropic locus.

Abou Daya F; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Mandigo T; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02114, USA., Ober L; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Patel D; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Maher M; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Math S; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Tchio C; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Walker JA; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02114, USA., Saxena R; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02114, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Melkani GC; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.; UAB Nathan Shock Center, Birmingham, AL 35294, USA.

Journal Article , 2025

FBXO22 deficiency defines a pleiotropic syndrome of growth restriction and multi-system anomalies associated with a unique epigenetic signature.

Ramakrishna NB; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore., Mohamad Sahari UB; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore; Department of Biochemistry, National University of Singapore, Singapore 119260, Singapore., Johmura Y; Division of Cancer and Senescence Biology, Cancer Research Institute, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa, Japan., Ali NA; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore., Alghamdi M; Unit of Medical Genetics, Department of Pediatrics, College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia., Bauer P; Centogene AG, Rostock, Germany., Khan S; Centogene AG, Rostock, Germany., Ordoñez N; Centogene AG, Rostock, Germany., Ferreira M; Centogene AG, Rostock, Germany., Pinto Basto J; Centogene AG, Rostock, Germany., Alkuraya FS; Department of Translational Genomics, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Faqeih EA; Section of Medical Genetics, King Fahad Medical City, Children's Specialist Hospital, Riyadh, Saudi Arabia., Mori M; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA; Genetic and Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA., Almontashiri NAM; Center for Genetics and Inherited Diseases, Taibah University, 7534 Abdul Muhsin Ibn Abdul Aziz, Al Ihn, Al-Madinah al-Munawwarah 42318, Saudi Arabia; Faculty of Applied Medical Sciences, Taibah University, Janadah Bin Umayyah Road, Tayba, Al-Madinah al-Munawwarah 42353, Saudi Arabia., Al Shamsi A; Paediatrics Department, Tawam Hospital, Al-Ain, United Arab Emirates., ElGhazali G; HQ Medical Operations Division, Union 71, Abu Dhabi, United Arab Emirates., Abu Subieh H; Maternal Fetal Medicine Department, Kanad Hospital, Al Ain, United Arab Emirates., Al Ojaimi M; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., El-Hattab AW; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Said Al-Kindi SA; Department of Neonatology, Armed Forces Hospital, Muscat, Oman., Alhashmi N; Child Health Department, Royal Hospital, Muscat, Oman., Alhabshan F; Department of Cardiac Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia., Al Saman A; Pediatric Neurology Department, National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia., Tfayli H; Pediatric Endocrinology and Diabetes, American University of Beirut Medical Center (AUBMC), Beirut, Lebanon., Arabi M; Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology Division, Children's Heart Center, American University of Beirut Medical Center, Beirut, Lebanon., Khalifeh S; Pediatric Neurology Division, American University of Beirut Medical Center, Beirut, Lebanon., Taylor A; Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates., Alfadhel M; Genetics and Precision Medicine Department (GPM), King Abdullah Specialized Children's Hospital (KASCH), King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNG-HA), Riyadh, Saudi Arabia; Medical Genomic Research Department, King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Ministry of National Guard Health Affairs (MNG-HA), Riyadh, Saudi Arabia., Jain R; Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates., Sinha S; Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates., Shenbagam S; Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates., Ramachandran R; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates; Center for Genomic Discovery, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates., Altunoğlu U; Medical Genetics Department, Koç University School of Medicine (KUSOM), Istanbul 34010, Turkey., Jacob A; Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates; Dubai Health, Dubai, United Arab Emirates., Thalange N; Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates; Dubai Health, Dubai, United Arab Emirates., El Bejjani M; Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates; Dubai Health, Dubai, United Arab Emirates., Perrin A; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore., Shin JW; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore; Department of Biochemistry, National University of Singapore, Singapore 119260, Singapore., Al-Maawali A; Child Health Department, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Al-Shidhani A; Child Health Department, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Al-Futaisi A; Child Health Department, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Rabea F; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates., Chekroun I; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates., Almarri MA; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates; Genome Center, Dubai Police GHQ, Dubai, United Arab Emirates., Ohta T; Department of Translational Oncology, St. Marianna University Graduate School of Medicine, Kawasaki, Japan., Nakanishi M; Division of Cancer Cell Biology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan., Alsheikh-Ali A; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates; Dubai Health, Dubai, United Arab Emirates., Ali FR; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Dubai, United Arab Emirates; Center for Genomic Discovery, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates., Bertoli-Avella AM; Centogene AG, Rostock, Germany., Reversade B; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A(∗)STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore; Medical Genetics Department, Koç University School of Medicine (KUSOM), Istanbul 34010, Turkey; NUS Cardiovascular-Metabolic Disease Translational Research Programme (CVMD-TRP), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore; Laboratory of Human Genetics & Therapeutics, Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia. Electronic address: bruno@reversade.com., Abou Tayoun A; Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates; Center for Genomic Discovery, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates. Electronic address: ahmad.tayoun@dubaihealth.ae.

Journal Article , 2025

Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations.

Malone SG; Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD, USA., Davis CN; Mental Illness Research, Education and Clinical Center, Crescenz VA Medical Center, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Piserchia Z; Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD, USA., Setzer MR; Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD, USA., Toikumo S; Mental Illness Research, Education and Clinical Center, Crescenz VA Medical Center, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhou H; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale University School of Medicine, New Haven, CT, USA., Winterlind EL; Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD, USA., Gelernter J; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Justice A; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale University School of Public Health, New Haven, CT, USA., Leggio L; Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Baltimore, MD, USA.; Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, RI, USA.; Division of Addiction Medicine, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Rentsch CT; Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.; London School of Hygiene and Tropical Medicine, London, UK., Kranzler HR; Mental Illness Research, Education and Clinical Center, Crescenz VA Medical Center, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gray JC; Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD, USA. Joshua.gray@usuhs.edu.

Journal Article , 2025

Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.

Shou W; Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Institute of Pediatrics, Kunming Children's Hospital, 288 Qianxing Road, Kunming, Yunnan, 650228, P.R. China. shouwh_chgc@163.com.; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China. shouwh_chgc@163.com., Zhang C; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China., Wang Y; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China., Wang H; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China., Guo L; Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Institute of Pediatrics, Kunming Children's Hospital, 288 Qianxing Road, Kunming, Yunnan, 650228, P.R. China., Li L; Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Institute of Pediatrics, Kunming Children's Hospital, 288 Qianxing Road, Kunming, Yunnan, 650228, P.R. China., Zhang T; Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Institute of Pediatrics, Kunming Children's Hospital, 288 Qianxing Road, Kunming, Yunnan, 650228, P.R. China. zts68420@sina.com., Huang W; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China., Shi J; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), 2140 Xietu Road, Shanghai, 200032, P.R. China. shijx@chgc.sh.cn.

Journal Article , 2025

Stable pleotropic loci controlling the accumulation of multiple nutritional elements in wheat.

Joukhadar R; Agriculture Victoria, Centre for AgriBioscience, AgriBio, Bundoora, VIC, Australia. r.joukhadar@agrisapiens.com.au., Trethowan RM; School of Life and Environmental Sciences, Plant Breeding Institute, Sydney Institute of Agriculture, The University of Sydney, Narrabri, NSW, Australia. richard.trethowan@sydney.edu.au.; School of Life and Environmental Sciences, Plant Breeding Institute, Sydney Institute of Agriculture, The University of Sydney, Cobbitty, NSW, Australia. richard.trethowan@sydney.edu.au., Thistlethwaite R; School of Life and Environmental Sciences, Plant Breeding Institute, Sydney Institute of Agriculture, The University of Sydney, Narrabri, NSW, Australia., Hayden MJ; Agriculture Victoria, Centre for AgriBioscience, AgriBio, Bundoora, VIC, Australia.; School of Applied Systems Biology, La Trobe University, Bundoora, VIC, Australia., Stangoulis J; College of Science and Engineering, Flinders University, Sturt Road, Bedford Park, South Australia, 5042, Australia., Cu S; College of Science and Engineering, Flinders University, Sturt Road, Bedford Park, South Australia, 5042, Australia., Tibbits J; Agriculture Victoria, Centre for AgriBioscience, AgriBio, Bundoora, VIC, Australia., Daetwyler HD; Agriculture Victoria, Centre for AgriBioscience, AgriBio, Bundoora, VIC, Australia.

Journal Article , 2025

Transcriptional Reprogramming and Allelic Variation in Pleiotropic QTL Regulates Days to Flowering and Growth Habit in Pigeonpea.

Kumar K; ICAR-National Institute for Plant Biotechnology, New Delhi, India.; ICAR-Indian Institute of Pulses Research, Kanpur, India.; The Graduate School, ICAR-Indian Agricultural Research Institute, New Delhi, India., Durgesh K; ICAR-Indian Agricultural Research Institute, Division of Genetics, New Delhi, India., Anjoy P; ICAR-Indian Agricultural Statistical Research Institute, New Delhi, India., Srivastava H; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Tribhuvan KU; ICAR-Indian Institute of Agricultural Biotechnology, Ranchi, India., Sevanthi AM; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Singh A; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Prabha R; Agricultural Knowledge Management Unit, ICAR-Indian Agricultural Research Institute, New Delhi, India., Sharma S; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Joshi R; ICAR-Indian Agricultural Research Institute, Division of Genetics, New Delhi, India., Jain PK; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Singh NK; ICAR-National Institute for Plant Biotechnology, New Delhi, India., Gaikwad K; ICAR-National Institute for Plant Biotechnology, New Delhi, India.

Journal Article , 2025

The mosaicism of Cas-induced mutations and pleiotropic effects of scarlet gene in an emerging model system.

Xu S; Division of Biological Sciences, University of Missouri, Columbia, MO, 65211, USA. sxwf7@umsystem.edu., Neupane S; Division of Biological Sciences, University of Missouri, Columbia, MO, 65211, USA., Wang H; Department of Biology, University of Texas at Arlington, Arlington, TX, 76019, USA.; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, 75235, USA., Pham TP; Department of Biology, University of Texas at Arlington, Arlington, TX, 76019, USA., Snyman M; Department of Biology, University of Texas at Arlington, Arlington, TX, 76019, USA.; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 75235, USA., Huynh TV; Division of Biological Sciences, University of Missouri, Columbia, MO, 65211, USA., Wang L; Division of Biological Sciences, University of Missouri, Columbia, MO, 65211, USA.

Journal Article , 2025

Extranuclear function of Arabidopsis HOOKLESS1 regulates pleiotropic developmental processes in a non-cell-autonomous manner.

Nobusawa T; Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-3 Kagamiyama, Higashi-Hiroshima, 739-8526, Japan., Matsushima N; Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-3 Kagamiyama, Higashi-Hiroshima, 739-8526, Japan., Ueda H; Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-3 Kagamiyama, Higashi-Hiroshima, 739-8526, Japan., Yumoto E; Advanced Instrumental Analysis Center, Teikyo University, 1-1 Toyosatodai, Utsunomiya, Tochigi, 320-8551, Japan., Asahina M; Advanced Instrumental Analysis Center, Teikyo University, 1-1 Toyosatodai, Utsunomiya, Tochigi, 320-8551, Japan.; Department of Biosciences, Teikyo University, 1-1 Toyosatodai, Utsunomiya, Tochigi, 320-8551, Japan., Kusaba M; Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-3 Kagamiyama, Higashi-Hiroshima, 739-8526, Japan.

Journal Article , 2025

Genetic correlation, pleiotropic loci and shared risk genes between major depressive disorder and gastrointestinal tract disorders.

Zhou S; Healthy Food Evaluation Research Center, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China., Zi J; Healthy Food Evaluation Research Center, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China., Hu Y; Healthy Food Evaluation Research Center, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China., Wang X; Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Maternal & Child Nutrition Center, West China Second University Hospital, Sichuan University, Chengdu, China., Cheng G; Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Maternal & Child Nutrition Center, West China Second University Hospital, Sichuan University, Chengdu, China. Electronic address: gcheng@scu.edu.cn., Xiong J; Healthy Food Evaluation Research Center, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu 610041, China. Electronic address: jzx0004@tigermail.auburn.edu.

Journal Article , 2025

A pleiotropy scan to discover new susceptibility loci for pancreatic ductal adenocarcinoma.

Giaccherini M; Department of Biology, University of Pisa, Pisa, Italy., Rende M; Department of Biology, University of Pisa, Pisa, Italy., Gentiluomo M; Department of Biology, University of Pisa, Pisa, Italy., Corradi C; Department of Biology, University of Pisa, Pisa, Italy., Archibugi L; Digestive and Liver Disease Unit, Sant'Andrea Hospital, Rome, Italy.; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Ermini S; Blood Transfusion Service, Azienda Ospedaliero Universitaria Meyer, Florence, Italy., Maiello E; Department of Oncology, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Italy., Morelli L; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., van Eijck CHJ; Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Cavestro GM; Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, IRCCS San Raffaele, Milan, Italy., Schneider M; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany., Mickevicius A; Surgery Department, Lithuanian University of Health Sciences, Kaunas, Lithuania., Adamonis K; Gastroenterology Department, Lithuanian University of Health Sciences, Kaunas, Lithuania., Basso D; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy., Hlavac V; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Gioffreda D; Division of Gastroenterology and Research Laboratory, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Italy., Talar-Wojnarowska R; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland., Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany., Lovecek M; Department of Surgery I, University Hospital Olomouc, Olomouc, Czech Republic., Vanella G; Digestive and Liver Disease Unit, Sant'Andrea Hospital, Rome, Italy.; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Gazouli M; Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Uno M; Center for Translational Research in Oncology (LIM24), Instituto Do Câncer Do Estado de São Paulo, (ICESP), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, Brazil., Malecka-Wojciesko E; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland., Vodicka P; Institute of Experimental Medicine, Czech Academy of Science, Prague, Czech Republic.; Institute of Biology and Medical Genetics, 1st Medical Faculty, Charles University in Prague, Prague, Czech Republic., Goetz M; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bijlsma MF; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC and Cancer Center Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Amsterdam, The Netherlands., Petrone MC; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Bazzocchi F; Department of Surgery, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Italy., Kiudelis M; Surgery Department, Lithuanian University of Health Sciences, Kaunas, Lithuania., Szentesi A; Medical School, Institute for Translational Medicine, University of Pécs, Pécs, Hungary.; János Szentágothai Research Center, University of Pécs, Pécs, Hungary.; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.; Centre for Translational Medicine, Department of Medicine, University of Szeged, Szeged, Hungary., Carrara S; Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center IRCCS, Milan, Italy., Nappo G; Pancreatic Unit, Humanitas Clinical and Research Center IRCCS, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Milanetto AC; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy., Soucek P; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Katzke V; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Peduzzi G; Department of Biology, University of Pisa, Pisa, Italy., Rizzato C; Department of Biology, University of Pisa, Pisa, Italy., Pasquali C; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy., Chen X; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany., Capurso G; Digestive and Liver Disease Unit, Sant'Andrea Hospital, Rome, Italy.; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Hackert T; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany., Bueno-de-Mesquita B; Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Uzunoglu FG; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hegyi P; Medical School, Institute for Translational Medicine, University of Pécs, Pécs, Hungary.; János Szentágothai Research Center, University of Pécs, Pécs, Hungary.; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.; Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Budapest, Hungary., Greenhalf W; Institute for Health Research Liverpool Pancreas Biomedical Research Unit, University of Liverpool, Liverpool, United Kingdom., Theodoropoulos GE; First Department of Propaedeutic Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece., Sperti C; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy., Perri F; Division of Gastroenterology and Research Laboratory, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Italy., Oliverius M; Surgery Clinic Third Faculty of Medicine, Charles University, Prague, Czech Republic., Mambrini A; Oncological Department Massa Carrara, Azienda USL Toscana Nord Ovest, Carrara, Italy., Tavano F; Division of Gastroenterology and Research Laboratory, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Italy., Farinella R; Department of Biology, University of Pisa, Pisa, Italy., Arcidiacono PG; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Lucchesi M; Oncological Department Massa Carrara, Azienda USL Toscana Nord Ovest, Carrara, Italy., Bunduc S; Medical School, Institute for Translational Medicine, University of Pécs, Pécs, Hungary.; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.; Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Fundeni Clinical Institute, Bucharest, Romania., Kupcinskas J; Gastroenterology Department, Lithuanian University of Health Sciences, Kaunas, Lithuania., Di Franco G; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Stocker H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany., Neoptolemos JP; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany., Bambi F; Blood Transfusion Service, Azienda Ospedaliero Universitaria Meyer, Florence, Italy., Jamroziak K; Department of Hematology, Transplantology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland., Testoni SGG; Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, IRSSC San Raffaele Scientific Institute, Milan, Italy., Aoki MN; Laboratory for Applied Science and Technology in Health, Carlos Chagas Institute, Oswaldo Cruz Foundation (Fiocruz), Curitiba, Brazil., Mohelnikova-Duchonova B; Department of Oncology, Palacky University Olomouc, Olomouc, Czech Republic., Izbicki JR; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Pezzilli R; County Medical Association of Potenza, Potenza, Italy., Lawlor RT; ARC-NET: Centre for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy., Kauffmann EF; Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy., López de Maturana E; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Malats N; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Campa D; Department of Biology, University of Pisa, Pisa, Italy.

Journal Article; Meta-Analysis , 2025