Sökresultat - "Podzimkova, Nada"

Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

Champiat, Stephane ^{1, 13, 15, ∗}, Garralda, Elena ², Galvao, Vladimir ², Cassier, Philippe A. ³, Gomez-Roca, Carlos ⁴, Korakis, Iphigenie ⁴, Grell, Peter ⁵, Naing, Aung ⁶, LoRusso, Patricia ⁷, Mikyskova, Romana ⁸, Podzimkova, Nada ⁹, Reinis, Milan ⁸, Ouali, Kaissa ¹, Schoenenberger, Andreu ⁹, Kiemle-Kallee, Joachim ¹⁰, Tillmanns, Sascha ¹⁰, Sachse, Richard ¹⁰, Moebius, Ulrich ⁹, Spisek, Radek ⁹, Bechard, David ¹¹, Jelinkova, Lenka Palova ^{9, 12, 14}, Adkins, Irena ^{9, 12, 14}, Marabelle, Aurelien ^{1, 14}

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Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v.

Matuskova H; SOTIO Biotech a.s, Prague, Czech Republic., Marasek P; SOTIO Biotech a.s, Prague, Czech Republic., Mazhara V; Laboratory of Tumor Immunology, Institute of Microbiology Czech Academy of Sciences, Prague, Czech Republic., Simonova E; SOTIO Biotech a.s, Prague, Czech Republic., Kosinova L; SOTIO Biotech a.s, Prague, Czech Republic., Danek P; SOTIO Biotech a.s, Prague, Czech Republic., Danova K; SOTIO Biotech a.s, Prague, Czech Republic., Sajnerova K; SOTIO Biotech a.s, Prague, Czech Republic., Malatova I; SOTIO Biotech a.s, Prague, Czech Republic., Hrabankova K; SOTIO Biotech a.s, Prague, Czech Republic., Greco D; SOTIO Biotech a.s, Prague, Czech Republic., Martinec O; SOTIO Biotech a.s, Prague, Czech Republic., Fabisik M; SOTIO Biotech a.s, Prague, Czech Republic., Podzimkova N; SOTIO Biotech a.s, Prague, Czech Republic., Hladikova K; SOTIO Biotech a.s, Prague, Czech Republic., Behalova K; Laboratory of Tumor Immunology, Institute of Microbiology Czech Academy of Sciences, Prague, Czech Republic., Antosova Z; SOTIO Biotech a.s, Prague, Czech Republic., Sirova M; Laboratory of Tumor Immunology, Institute of Microbiology Czech Academy of Sciences, Prague, Czech Republic., Mikyskova R; Laboratory of Immunological and Tumor models, Institute of Molecular Genetics Czech Academy of Sciences, Prague, Czech Republic., Reinis M; Laboratory of Immunological and Tumor models, Institute of Molecular Genetics Czech Academy of Sciences, Prague, Czech Republic., Kovar M; Laboratory of Tumor Immunology, Institute of Microbiology Czech Academy of Sciences, Prague, Czech Republic., Béchard D; Cytune Pharma S.A.S, Nantes, France., Moebius U; SOTIO Biotech a.s, Prague, Czech Republic., Palova Jelinkova L; SOTIO Biotech a.s, Prague, Czech Republic.; Department of Immunology, 2nd Faculty of Medicine and University Hospital Motol, Charles University, Prague, Czech Republic., Spisek R; SOTIO Biotech a.s, Prague, Czech Republic.; Department of Immunology, 2nd Faculty of Medicine and University Hospital Motol, Charles University, Prague, Czech Republic., Steegmaier M; SOTIO Biotech a.s, Prague, Czech Republic., Adkins I; SOTIO Biotech a.s, Prague, Czech Republic adkins@sotio.com.; Department of Immunology, 2nd Faculty of Medicine and University Hospital Motol, Charles University, Prague, Czech Republic.

Journal Article , 2025