Search Results - "Polyether"

Antibacterial and cytotoxic angucyclines discovered by heterologous expression of a type II polyketide gene cluster.

Xu X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao 266237, China., Li J; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Wang L; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Yue X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Zhang F; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Lan D; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Zhang X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Xu H; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Che Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Zhu T; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Li D; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn., Xu X; Marine Biomedical Research Institute of Qingdao, Qingdao 266101, China., Zhang G; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China. zhangguojian@ouc.edu.cn.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao 266237, China.; Marine Biomedical Research Institute of Qingdao, Qingdao 266101, China.

Journal Article , 2025

Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins.

Fallon TR; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego, La Jolla, CA 92093, USA., Shende VV; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego, La Jolla, CA 92093, USA., Wierzbicki IH; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Pendleton AL; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Plant Biology, Purdue University, West Lafayette, IN 47907, USA., Watervoort NF; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Plant Biology, Purdue University, West Lafayette, IN 47907, USA., Auber RP; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Plant Biology, Purdue University, West Lafayette, IN 47907, USA., Gonzalez DJ; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Wisecaver JH; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.; Purdue Center for Plant Biology, Purdue University, West Lafayette, IN 47907, USA., Moore BS; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego, La Jolla, CA 92093, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. , 2024

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Simulated ischemia in live cerebral slices is mimicked by opening the Na ⁺ /K ⁺ pump: clues to the generation of spreading depolarization.

Kim D; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Gagolewicz P; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., McQueen S; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Latour H; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Tresidder K; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Jarvis CR; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Andrew RD; Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada.

Journal Article , 2025

Eribulin efficacy in long responder patients with metastatic breast cancer: A multicentric observational study.

Passildas J; Division de Recherche Clinique, Délégation Recherche Clinique & Innovation, Centre Jean Perrin, Centre de Lutte contre le Cancer, 58 rue Montalembert, F-63000, Clermont-Ferrand, France; Centre d'Investigation Clinique, UMR501, Clermont-Ferrand 63011, France; Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont-Ferrand F-63000, France. Electronic address: Judith.passildas@clermont.unicancer.fr., Paillard MJ; Medical Oncology, CHRU Besancon - Hopital Jean Minjoz, Besançon, France. Electronic address: mjpaillard@chu-besancon.fr., Uwer L; Medical Oncology, Institut de Cancérologie de Lorraine - Alexis Vautrin, Vandoeuvre Les Nancy, France. Electronic address: l.uwer@nancy.unicancer.fr., Molnar I; Division de Recherche Clinique, Délégation Recherche Clinique & Innovation, Centre Jean Perrin, Centre de Lutte contre le Cancer, 58 rue Montalembert, F-63000, Clermont-Ferrand, France; Centre d'Investigation Clinique, UMR501, Clermont-Ferrand 63011, France; Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont-Ferrand F-63000, France. Electronic address: Ioana.molnar@clermont.unicancer.fr., Dohollou N; Oncology, Polyclinique Bordeaux Nord Aquitaine, Bordeaux, France. Electronic address: n.dohollou@bordeauxnord.com., Petit T; Medical Oncology, Centre Paul Strauss Centre de Lutte contre le Cancer, Strasbourg, France. Electronic address: TPetit@strasbourg.unicancer.fr., Hajjaji N; Medical oncology, Centre Oscar Lambret, Lille, France. Electronic address: n-hajjaji@o-lambret.fr., Boudin L; Medical Oncology, Hôpital d'Instruction des Armées (HIA) Ste Anne, Toulon, France. Electronic address: laurys84@hotmail.com., Lorgis V; Oncologue médical, Institut Cancérologie de Bourgogne, Dijon, France. Electronic address: vlorgis@icb-cancer.fr., Jacquin JP; Medical Oncology, Institut de Cancérologie Lucien Neuwirth, Saint-Étienne, France. Electronic address: jean-philippe.jacquin@chu-st-etienne.fr., Abrial C; Division de Recherche Clinique, Délégation Recherche Clinique & Innovation, Centre Jean Perrin, Centre de Lutte contre le Cancer, 58 rue Montalembert, F-63000, Clermont-Ferrand, France; Centre d'Investigation Clinique, UMR501, Clermont-Ferrand 63011, France; Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont-Ferrand F-63000, France. Electronic address: Catherine.abrial@clermont.unicancer.fr., Mouret-Reynier MA; Medical Oncology, Jean Perrin, Centre de Lutte contre le Cancer, 58 rue Montalembert, Clermont-Ferrand F-63000, France. Electronic address: Marie-ange.mouret-reynier@clermont.unicancer.fr.

Journal Article; Observational Study; Multicenter Study , 2025

Eribulin exerts multitarget antineoplastic activity in glioma cells.

Alcântara GAS; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil., do Nascimento MC; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil.; Laboratory of Medical Investigation in Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Internal Medicine, Hematology Division, Faculdade de Medicina, University of São Paulo, São Paulo, 01246-903, Brazil., de Miranda LBL; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil., de Almeida BO; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil., Lima K; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil.; Laboratory of Medical Investigation in Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Internal Medicine, Hematology Division, Faculdade de Medicina, University of São Paulo, São Paulo, 01246-903, Brazil., Rego EM; Laboratory of Medical Investigation in Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Internal Medicine, Hematology Division, Faculdade de Medicina, University of São Paulo, São Paulo, 01246-903, Brazil., Costa-Lotufo LV; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil., Machado-Neto JA; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, São Paulo, SP, CEP 05508-900, Brazil. jamachadoneto@usp.br.

Journal Article , 2025

Salinomycin inhibits porcine epidemic diarrhea virus infection by targeting Wnt/β-catenin pathway.

Yuan C; College of Veterinary Medicine, Hebei Agricultural University; Veterinary Biological Technology Innovation Center of Hebei Province, Baoding 071000, China., Ma Y; College of Veterinary Medicine, Hebei Agricultural University; Veterinary Biological Technology Innovation Center of Hebei Province, Baoding 071000, China., Wang W; College of Veterinary Medicine, Hebei Agricultural University; Veterinary Biological Technology Innovation Center of Hebei Province, Baoding 071000, China., Wang Y; College of Veterinary Medicine, Hebei Agricultural University; Veterinary Biological Technology Innovation Center of Hebei Province, Baoding 071000, China., Shi X; Handan City Rural Revitalization Promotion Center, Handan 056004, Hebei Province, China., Song Q; College of Veterinary Medicine, Hebei Agricultural University; Veterinary Biological Technology Innovation Center of Hebei Province, Baoding 071000, China. Electronic address: songqinye@126.com.

Journal Article , 2025

Effect of Substituting Polyether Ionophore Anticoccidial Drugs With 1, 8-Cineole for the Control of Eimeria Infections in Broilers.

Sun J; School of Chemical Engineering and Technology, Tianjin University, Tianjin, The People's Republic of China.; Tianjin Naer Biotechnology Co., LTD., Tianjin, The People's Republic of China., Bao W; Tianjin Naer Biotechnology Co., LTD., Tianjin, The People's Republic of China., Han Y; School of Chemical Engineering and Technology, Tianjin University, Tianjin, The People's Republic of China., Zhang R; Tianjin Naer Biotechnology Co., LTD., Tianjin, The People's Republic of China., Zhou Z; School of Chemical Engineering and Technology, Tianjin University, Tianjin, The People's Republic of China.

Journal Article , 2025

HT1080 Human Fibrosarcoma Cells Selected for Super-eribulin Resistance In Vitro Become More Malignant and Are Arrested Synergistically by Methionine Restriction in Combination With Eribulin in Nude Mice.

Morinaga S; AntiCancer Inc., San Diego, CA, U.S.A.; Department of Surgery, University of California, San Diego, CA, U.S.A.; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Mizuta K; AntiCancer Inc., San Diego, CA, U.S.A.; Department of Surgery, University of California, San Diego, CA, U.S.A., Kang BM; AntiCancer Inc., San Diego, CA, U.S.A.; Department of Surgery, University of California, San Diego, CA, U.S.A., Han Q; AntiCancer Inc., San Diego, CA, U.S.A., Bouvet M; Department of Surgery, University of California, San Diego, CA, U.S.A., Yamamoto N; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hayashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Kimura H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Miwa S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Igarashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Higuchi T; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Tsuchiya H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Demura S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hoffman RM; AntiCancer Inc., San Diego, CA, U.S.A.; all@anticancer.com.; Department of Surgery, University of California, San Diego, CA, U.S.A.

Journal Article , 2025

The Effectiveness and Adverse Events of Eribulin Monotherapy in Indonesian Metastatic Breast Cancer (MBC) Patients.

Adiputra PAT; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Department of Surgery, Prof Dr IGNG Ngoerah General Hospital/Universitas Udayana, Denpasar, Bali, Indonesia., Siswiandari KM; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Gatot Soebroto Army Hospital, Jakarta, Indonesia., Hangesti D; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Gatot Soebroto Army Hospital, Jakarta, Indonesia., Qodir N; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Department of Surgery, Moh. Hoesin General Hospital /Universitas Sriwijaya, Palembang, Indonesia., Gautama W; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Dharmais Cancer Hospital - National Cancer Center, Jakarta, Indonesia., Hermansyah D; Indonesian Society of Surgical Oncology (ISSO), Indonesia.; Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Journal Article; Multicenter Study , 2025

Development and internal validation of a predictive model of overall and progression-free survival in eribulin-treated patients with breast cancer based on baseline peripheral blood parameters.

Natori K; Department of Surgery, Division of Breast and Endocrine Surgery, School of Medicine, Hyogo Medical University, 1-1 Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.; Department of Breast Surgery, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku, Tokyo, 162-8666, Japan., Igeta M; Department of Biostatistics, School of Medicine, Hyogo Medical University, 1-1 Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan., Morimoto T; Department of Breast Surgery, Yao Municipal Hospital, 1-3-1 Ryuge-Cho, Yao, Osaka, 581-0069, Japan., Nagahashi M; Department of Surgery, Division of Breast and Endocrine Surgery, School of Medicine, Hyogo Medical University, 1-1 Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan., Akashi-Tanaka S; Department of Breast Surgery, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku, Tokyo, 162-8666, Japan., Daimon T; Department of Biostatistics, School of Medicine, Hyogo Medical University, 1-1 Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan., Miyoshi Y; Department of Surgery, Division of Breast and Endocrine Surgery, School of Medicine, Hyogo Medical University, 1-1 Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan. ymiyoshi@hyo-med.ac.jp.

Journal Article; Validation Study , 2025

Selective tubulin-binding drugs induce pericyte phenotype switching and anti-cancer immunity.

He B; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Wood KH; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Li ZJ; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia.; Department of Geriatrics and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Guangdong, P. R. China., Ermer JA; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Li J; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Bastow ER; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Sakaram S; INSiGENe Pty Ltd, UGenome, Tucson, AZ, USA., Darcy PK; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Spalding LJ; Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Redfern CT; Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia., Canes J; SOLTI Cancer Research Group, Barcelona, Spain., Oliveira M; SOLTI Cancer Research Group, Barcelona, Spain.; Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.; Breast Cancer Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Prat A; SOLTI Cancer Research Group, Barcelona, Spain.; Medical Oncology Department, Hospital Clinic of Barcelona, Barcelona, Spain.; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Cortes J; SOLTI Cancer Research Group, Barcelona, Spain.; Medica Scientia Innovation Research (MEDSIR)-Oncoclínicas&Co, Jersey City, NJ, USA.; Medica Scientia Innovation Research (MEDSIR)-Oncoclínicas&Co, Sao Paulo, Brazil.; International Breast Cancer Center (IBCC), Pangaea Oncology, Quiron Group, Barcelona, Spain.; Faculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.; IOB Madrid, Institute of Oncology, Hospital Beata María Ana, Madrid, Spain., Thompson EW; School of Biomedical Sciences and Centre for Genomics and Personalised Health, Faculty of Health, Queensland University of Technology (QUT) and Translational Research Institute, Brisbane, Australia., Littlefield BA; Eisai Inc., Cambridge, MA, USA., Redfern A; Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia.; Fiona Stanley Hospital, Perth, WA, Australia., Ganss R; Cancer Microenvironment Laboratory, Harry Perkins Institute of Medical Research, Centre for Medical Research, The University of Western Australia, Perth, WA, Australia. ganss@perkins.uwa.edu.au.

Journal Article , 2025

High Affinity Aptamers and Their Specificity for Azaspiracid-2 Using Capture-SELEX.

Yang J; Basic Medical College, Naval Medical University, Shanghai 200433, China., Li X; Basic Medical College, Naval Medical University, Shanghai 200433, China., Sun W; Basic Medical College, Naval Medical University, Shanghai 200433, China., Cui Y; Basic Medical College, Naval Medical University, Shanghai 200433, China., Chen H; Basic Medical College, Naval Medical University, Shanghai 200433, China., Yang Y; Basic Medical College, Naval Medical University, Shanghai 200433, China., Sun M; Basic Medical College, Naval Medical University, Shanghai 200433, China., Wang L; Basic Medical College, Naval Medical University, Shanghai 200433, China.

Journal Article , 2025

Dichloroacetate and Salinomycin as Therapeutic Agents in Cancer.

Hunt S; Department of Chemistry and Biochemistry, Oberlin College, 173 W Lorain St, Oberlin, OH 44074, USA., Thyagarajan A; Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Dayton, OH 45435, USA., Sahu RP; Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Dayton, OH 45435, USA.

Journal Article; Review , 2025

Salinomycin and oxaliplatin synergistically enhances cytotoxic effect on human colorectal cancer cells in vitro and in vivo.

Liu F; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China.; Department of Geriatrics, Gastroenterology, Qilu Hospital of Shandong University, 107 Wenhuaxi Road, Jinan, 250012, Shandong, China., Lv R; Postdoctoral Working Station, Liaocheng People's Hospital, 252000, Liaocheng, Shandong, China.; Department of Radiology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China.; Department of PET/CT, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Qiao X; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital & Institute, Haidian District, Beijing, 100142, China., Lv G; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Yuan H; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Han J; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Wang X; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Wan J; Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, Shandong, China., Wang M; Department of Geriatrics, Gastroenterology, Qilu Hospital of Shandong University, 107 Wenhuaxi Road, Jinan, 250012, Shandong, China. doctorminmin@163.com.; Shandong Key Laboratory of Cardiovascular Proteomics, Jinan, 250012, Shandong, China. doctorminmin@163.com.

Journal Article , 2025

Potential threat of environmental toxin palytoxin to cerebral nerves: A mechanism study in vitro and in vivo.

Zhang X; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: zhang_jn0307@163.com., Huang L; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. Electronic address: huanglei_research@126.com., Liu Y; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: 1480588460@qq.om., Li X; Department of General Practice Characteristic Medical Center of Chinese People Armed Police Force, Tianjin 300300, China. Electronic address: lixuewen7501@163.com., Zhou H; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: zhouhytj@163.com., Qin K; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: qinkang2020@foxmail.com., Li S; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: liza3320@163.com., Ren S; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: renshuyue2018@163.com., Jia X; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: jiaxueling0506@163.com., Gao Z; Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Sciences, Tianjin 300050, China. Electronic address: gaozhx@163.com.

Journal Article , 2025

Trastuzumab-Pertuzumab Plus Eribulin or Taxane as First-Line Chemotherapy for Human Epidermal Growth Factor 2-Positive Locally Advanced/Metastatic Breast Cancer: The Randomized Noninferiority Phase III EMERALD Trial.

Yamashita T; Department of Breast Surgery and Oncology, Kanagawa Cancer Center, Kanagawa, Japan., Saji S; Department of Medical Oncology, Fukushima Medical University, Fukushima, Japan., Takano T; Department of Breast Medical Oncology, The Cancer Institute Hospital of JFCR, Tokyo, Japan., Naito Y; Department of General Internal Medicine, National Cancer Center Hospital East, Chiba, Japan., Tsuneizumi M; Department of Breast Surgery, Shizuoka General Hospital, Shizuoka, Japan., Yoshimura A; Department of Breast Oncology, Aichi Cancer Center Hospital, Aichi, Japan., Takahashi M; Department of Breast Surgery, Hokkaido University Hospital, Hokkaido, Japan., Tsurutani J; Advanced Cancer Translational Research Institute, Showa University, Tokyo, Japan., Iwatani T; Breast and Endocrine Surgery, Okayama University Hospital, Okayama, Japan., Kitada M; Department of Breast Disease Center, Asahikawa Medical University Hospital, Hokkaido, Japan., Tada H; Department of Surgery, Division of Breast and Endocrine Surgery, Tohoku University Hospital, Miyagi, Japan., Mori N; Department of Breast Surgery, Seirei Hamamatsu General Hospital, Shizuoka, Japan., Higuchi T; Department of Breast Unit, Japanese Red Cross Saitama Hospital, Saitama, Japan., Iwasa T; Department of Medical Oncology, Kindai University Hospital, Osaka, Japan., Araki K; Department of Breast Medical Oncology, Gunma Prefectural Cancer Center, Gunma, Japan., Koizumi K; Department of Surgery 1, Division of Breast Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan., Hasegawa H; Medical HQs, Eisai Co, Ltd, Tokyo, Japan., Uchida Y; Medical HQs, Eisai Co, Ltd, Tokyo, Japan., Morita S; Department of Biomedical Statistics and Bioinformatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Masuda N; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study , 2025

The impact of different levels of functional oil supplementation in combination with salinomycin on growth performance and intestinal microbiota of broilers undergoing Eimeria challenge: An analysis of dynamics.

Stefanello TB; Department of Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Cardinal KM; Department of Animal Science, Instituto Federal Farroupilha, Alegrete, RS, Brazil., Orso C; Department of Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Franceschi CH; Department of Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Silva JP; Department of Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Mann MB; Institute of Food Science and Technology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Frazzon J; Institute of Food Science and Technology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Moraes PO; Department of Animal Science and Rural Development, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil., Ribeiro AML; Department of Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: aribeiro@ufrgs.br.

Journal Article , 2024

Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma.

Azumi M; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan. Electronic address: azumi@toyaku.ac.jp., Kusama K; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan., Yoshie M; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan., Nakano S; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan., Tsuru A; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan., Kato T; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan; Department of Gynecologic Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan., Tamura K; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan. Electronic address: hiro@toyaku.ac.jp.

Journal Article , 2024

Real-world treatment patterns and clinical outcomes in patients treated with eribulin after prior phosphoinositide 3-Kinase inhibitor treatment for metastatic breast cancer.

Goyal RK; RTI Health Solutions, Research Triangle Park, NC, USA., Zhang J; Eisai Inc, Nutley, NJ, USA., Davis KL; RTI Health Solutions, Research Triangle Park, NC, USA., Sluga-O'Callaghan M; RTI Health Solutions, Research Triangle Park, NC, USA., Kaufman PA; Larner College of Medicine, Division of Hematology/Oncology, University of Vermont Cancer Center, 111 Colchester Avenue, EP2, Burlington, VT, 05401, USA. Peter.Kaufman@uvmhealth.org.

Journal Article , 2024