Sökresultat - "RNA‐binding protein"

Evaluation of EWSR1/FUS rearrangements by FISH and NKX2.2 immunoexpression in simple bone cysts of the jaw.

Owosho AA; Department of Diagnostic Sciences, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN, USA; Department of Otolaryngology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: Aowosho@uthsc.edu., Shahrabi-Farahani S; Department of Diagnostic Sciences, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN, USA., DeColibus KA; Department of Diagnostic Sciences, College of Dentistry, The University of Tennessee Health Science Center, Memphis, TN, USA., Shasteen AM; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Summersgill KF; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Journal Article , 2024

Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain.

Selig EE; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Sohn EJ; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Stoja A; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Cell Systems and Anatomy, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Moreno-Romero AK; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Akula S; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Xu X; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Bishop AJR; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Cell Systems and Anatomy, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229., Libich DS; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.

Journal Article , 2025

Brain Metabolic Features of FUS-ALS: A 2-[ ¹⁸ F]FDG-PET Study.

Canosa A; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy.; Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy., Manera U; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy., Vasta R; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Zocco G; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Di Pede F; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Cabras S; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; University of Camerino, Center for Neuroscience, Camerino, Italy., De Mattei F; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Palumbo F; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Iazzolino B; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Minerva E; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Sbaiz L; Department of Clinical Pathology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Laboratory of Genetics, Turin, Italy., Brunetti M; Department of Clinical Pathology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Laboratory of Genetics, Turin, Italy., Gallone S; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy., Grassano M; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Matteoni E; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Polverari G; Positron Emission Tomography Center AFFIDEA-IRMET S.p.A, Turin, Italy., Fuda G; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Casale F; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Salamone P; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., De Marco G; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Marchese G; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Moglia C; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy., Calvo A; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy.; Neuroscience Institute of Turin (NIT), Turin, Italy., Pagani M; Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy.; Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden., Chiò A; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Neurology Unit 1U, Turin, Italy.; Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy.; Neuroscience Institute of Turin (NIT), Turin, Italy.

Journal Article , 2025

Investigating the role of conformational heterogeneity in FUS-RRM fibrillation.

Aazmi O; Department of Biology, Indian Institute of Science Education and Research (IISER), Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Aswale AR; Department of Biology, Indian Institute of Science Education and Research (IISER), Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Saju L; Department of Chemistry, Indian Institute of Science Education and Research, Thiruvananthapuram, Maruthamala P. O, Vithura, Kerala 695551, India., Chugh J; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Dr. Homi Bhabha Road, Pashan, Pune 411008, India. Electronic address: cjeet@iiserpune.ac.in.

Journal Article , 2025

DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases.

Ge R; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Chen M; School of Life Sciences and Medicine, Shandong University of Technology, Zibo, China., Wu S; Wisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China.; Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction), Xi'an Jiaotong-Liverpool University, Suzhou, China., Huang S; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China., Zhou P; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Cao M; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Zhang F; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Zang J; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Zhu Y; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Li J; School of Life Sciences and Medicine, Shandong University of Technology, Zibo, China., Ni G; Wisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China.; Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction), Xi'an Jiaotong-Liverpool University, Suzhou, China., Yang Z; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China., Li Q; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Pan W; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Zhang L; Research Center of Translational Medicine, Jinan Central Hospital Affiliated to Shandong First Medical University, Jinan, China., Liu M; Laboratory of Tissue Homeostasis, Haihe Laboratory of Cell Ecosystem, Tianjin, China.; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China., Xuan C; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China., Yu H; Department of Neuroscience, Genentech, South San Francisco, San Francisco, CA, USA. yu.haiyang@gene.com., Zhou J; Center for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China. junzhou@sdnu.edu.cn.; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China. junzhou@sdnu.edu.cn., Xie S; Department of Ophthalmology, Laboratory of Molecular Ophthalmology and Tianjin Key Laboratory of Ocular Trauma, Ministry of Education International Joint Laboratory of Ocular Diseases, Tianjin Institute of Eye Health and Eye Diseases, China-UK 'Belt and Road' Ophthalmology Joint Laboratory, Tianjin Medical University General Hospital, Tianjin, China. songboxie@tmu.edu.cn.

Journal Article , 2025

Net charge driven recruitment of supercharged GFP mutants into FUS droplets.

Kamagata K; Faculty of Engineering and Graduate School of Engineering, Gifu University, Yanagido 1-1, Gifu, 501-1193, Japan; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan; Department of Chemistry, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan; Graduate School of Life Sciences, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan. Electronic address: kamagata.kiyoto.p7@f.gifu-u.ac.jp., Hong Y; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan; Graduate School of Life Sciences, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan., Banerjee T; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan; Department of Chemistry, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan., Takahashi H; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan., Mano E; Faculty of Engineering and Graduate School of Engineering, Gifu University, Yanagido 1-1, Gifu, 501-1193, Japan.

Journal Article , 2025

Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.

Schweingruber C; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v. 16C, 106 91, Stockholm, Sweden.; Department of Cell and Molecular Biology, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden., Nijssen J; Department of Cell and Molecular Biology, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden.; Department of Neuroscience, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden., Mechtersheimer J; UK Dementia Research Institute Centre at King's College London, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Rd, SE5 9RX, London, United Kingdom., Reber S; UK Dementia Research Institute Centre at King's College London, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Rd, SE5 9RX, London, United Kingdom., Lebœuf M; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v. 16C, 106 91, Stockholm, Sweden.; Department of Cell and Molecular Biology, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden., O'Brien NL; UK Dementia Research Institute Centre at King's College London, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Rd, SE5 9RX, London, United Kingdom., Mei I; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v. 16C, 106 91, Stockholm, Sweden., Hedges E; UK Dementia Research Institute Centre at King's College London, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Rd, SE5 9RX, London, United Kingdom., Keuper M; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius v. 20C, 106 91, Stockholm, Sweden., Benitez JA; Department of Neuroscience, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden., Radoi V; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v. 16C, 106 91, Stockholm, Sweden., Jastroch M; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius v. 20C, 106 91, Stockholm, Sweden., Ruepp MD; UK Dementia Research Institute Centre at King's College London, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Rd, SE5 9RX, London, United Kingdom. marc-david.ruepp@kcl.ac.uk., Hedlund E; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v. 16C, 106 91, Stockholm, Sweden. eva.hedlund@dbb.su.se.; Department of Cell and Molecular Biology, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden. eva.hedlund@dbb.su.se.; Department of Neuroscience, Karolinska Institutet, Biomedicum, Solna v. 9, 171 77, Stockholm, Sweden. eva.hedlund@dbb.su.se.

Journal Article , 2025

Molecular insights into the effect of 1,6-hexanediol on FUS phase separation.

Zheng T; Department of Molecular Biology, Cell Biology & Biochemistry and Robert J. and Nancy D. Carney Institute for Brain Science, Brown University, Providence, RI, USA., Wake N; Therapeutic Sciences Graduate Program, Brown University, Providence, RI, USA., Weng SL; Department of Chemistry, Texas A&M University, College Station, TX, USA., Perdikari TM; Center for Biomedical Engineering, Brown University, Providence, RI, USA., Murthy AC; Molecular Biology, Cell Biology & Biochemistry Graduate Program, Brown University, Providence, RI, USA., Mittal J; Department of Chemistry, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu.; Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu.; Interdisciplinary Graduate Program in Genetics and Genomics, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu., Fawzi NL; Department of Molecular Biology, Cell Biology & Biochemistry and Robert J. and Nancy D. Carney Institute for Brain Science, Brown University, Providence, RI, USA. nicolas_fawzi@brown.edu.

Journal Article , 2025

The self-renewal function of Oct-4 can be replaced by the EWS-Oct-4 fusion protein in embryonic stem cells.

Lee EJ; Laboratory of Molecular and Cellular Biology, Department of Life Science, Sogang University, Seoul, 04107, Korea., Sun R; Laboratory of Molecular and Cellular Biology, Department of Life Science, Sogang University, Seoul, 04107, Korea., Kim J; Laboratory of Molecular and Cellular Biology, Department of Life Science, Sogang University, Seoul, 04107, Korea. jkim@sogang.ac.kr.; Stress-Responding Bionanomaterial Center, Sogang University, Seoul, 04107, Korea. jkim@sogang.ac.kr.

Journal Article , 2025

Probing the Formation and Liquid-to-Solid Transition of FUS Condensates via the Lifetimes of Fluorescent Proteins.

Ji J; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China., Xu K; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structures, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Wang W; School of Life Sciences, Technology Center for Protein Sciences, Tsinghua University, Beijing 100084, China., Chen C; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Journal Article , 2025

Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma.

Sohn EJ; Greehey Children's Cancer Research Institute and Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Libich DS; Greehey Children's Cancer Research Institute and Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Journal Article , 2025

Release of FUS into the extracellular space is regulated by its amino-terminal prion-like domain.

Nakaya T; School of Pharmacy at Fukuoka, International University of Health and Welfare, Fukuoka, Japan.

Journal Article , 2025

Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series.

Shneider NA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: ns327@cumc.columbia.edu., Harms MB; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Korobeynikov VA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Rifai OM; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Hoover BN; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Harrington EA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Aziz-Zaman S; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Singleton J; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Jamil A; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Madan VR; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Lee I; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Andrews JA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Smiley RM; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Alam MM; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Black LE; Charles River Laboratories, Wilmington, MA, USA., Shin M; College of Pharmacy, Sookmyung Women's University, Seoul, South Korea., Watts JK; UMass Chan Medical School, University of Massachusetts, Worcester, MA, USA., Walk D; University of Minnesota Medical School, Minneapolis, MN, USA., Newman D; Henry Ford Hospital, Detroit, MI, USA., Pascuzzi RM; Indiana University School of Medicine, Indianapolis, IN, USA., Weber M; Kantonsspital St Gallen, St Gallen, Switzerland., Neuwirth C; Kantonsspital St Gallen, St Gallen, Switzerland., Da Cruz S; VIB-KU Leuven Center for Brain and Disease Research, Department of Neurosciences, KU Leuven and Leuven Brain Institute, Leuven, Belgium., Soriano A; Ionis Pharmaceuticals, Carlsbad, CA, USA., Lane R; Ionis Pharmaceuticals, Carlsbad, CA, USA., Henry S; Ionis Pharmaceuticals, Carlsbad, CA, USA., Mathews J; Ionis Pharmaceuticals, Carlsbad, CA, USA., Jafar-Nejad P; Ionis Pharmaceuticals, Carlsbad, CA, USA., Norris D; Ionis Pharmaceuticals, Carlsbad, CA, USA., Rigo F; Ionis Pharmaceuticals, Carlsbad, CA, USA., Brown RH; Ionis Pharmaceuticals, Carlsbad, CA, USA., Miller S; Ionis Pharmaceuticals, Carlsbad, CA, USA., Crean R; Ionis Pharmaceuticals, Carlsbad, CA, USA., Bennett CF; Ionis Pharmaceuticals, Carlsbad, CA, USA.

Journal Article; Multicenter Study , 2025

A Cutaneous Vascular Neoplasm With an EWSR1-NFATC2 Translocation-Contributing to the Spectrum of Vascular Lesions Characterized by NFATC-Related Fusions.

Schurink B; Department of Pathology, Amsterdam University Medical Centers, the Netherlands., van Huizen AM; Department of Dermatology, Amsterdam University Medical Centers, the Netherlands., Savci-Heijink CD; Department of Pathology, Amsterdam University Medical Centers, the Netherlands., Kooi EJ; Department of Pathology, Amsterdam University Medical Centers, the Netherlands.

Case Reports; Journal Article , 2025

Spatiotemporal deciphering of dynamic the FUS interactome during liquid-liquid phase separation in living cells.

Song S; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Xie H; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Wang Q; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Sun X; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Xu J; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Chen R; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China., Zhu Y; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China., Jiang L; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China., Ding X; Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China. dingxianting@sjtu.edu.cn.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai, China. dingxianting@sjtu.edu.cn.

Journal Article , 2025

Sinonasal EWSR1::POU2AF3 sarcoma: a case report and literature review.

Çetin S; Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. sirmacetinn@gmail.com., Yılmaz İ; Department of Pathology, Abdulhamid Han Research and Training Hospital, University of Health Sciences, Istanbul, Turkey., Bakkaloğlu DV; Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey., Çelik M; Department of Otorhinolaryngology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey., Bilgiç B; Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey., Özlük Y; Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Journal Article; Case Reports; Review , 2025

EWSR1::BEND2 fusion sarcoma in bone: a report of two rare cases.

Çetin S; Istanbul Faculty of Medicine, Department of Pathology, Istanbul University, Istanbul, Turkey. sirmacetinn@gmail.com., Ünverengil G; Istanbul Faculty of Medicine, Department of Pathology, Istanbul University, Istanbul, Turkey., Yılmaz İ; Department of Pathology, Abdulhamid Han Research and Training Hospital, Istanbul, Turkey., Erdoğan N; Department of Pathology, Istanbul Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey., Danyeli AE; Department of Pathology, Acıbadem University Medical Faculty, Istanbul, Turkey., Salduz A; Istanbul Faculty of Medicine, Department of Orthopedics and Traumatology, Istanbul University, Istanbul, Turkey., Bilgiç B; Istanbul Faculty of Medicine, Department of Pathology, Istanbul University, Istanbul, Turkey.

Journal Article; Case Reports , 2025

EWSR1::SSX1 Fusion-Driven Synovial Sarcoma: A Case Presentation and Review of the Literature.

Vega-Gonzalez J; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Toro JAC; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., García EL; Department of Pathology, Hospital General Universitario Nuestra Señora del Prado, Talavera de la Reina, Toledo, Spain., Ospina GM; Department of Medical Oncology, Hospital Clinico San Carlos, School of Medicine, UCM, IdissC, EURACAN Referral Centre, Madrid, Spain., Serrano MT; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Gallardo AMC; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Giménez RB; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Martínez DH; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Egido AG; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., García LA; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Nielsen L; Department of Pathology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain., Plaza JC; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain., Medina LO; Department of Pathology, Hospital Universitario Clínico San Carlos, Health Research Institute 'San Carlos' (IdISCC), Universidad Complutense de Madrid, Madrid, Spain.

Case Reports; Journal Article; Review , 2025

Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter.

Cervera ST; Unidad de Tumores Sólidos Infantiles. Instituto de Investigación de Enfermedades Raras. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras. Instituto de Salud Carlos III (CB06/07/1009; CIBERER-ISCIII), Madrid, Spain.; Escuela de Doctorado. Universidad Autónoma de Madrid. Cantoblanco, Madrid, Spain., Martínez S; Unidad de Tumores Sólidos Infantiles. Instituto de Investigación de Enfermedades Raras. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain., Iranzo-Martínez M; Unidad de Tumores Sólidos Infantiles. Instituto de Investigación de Enfermedades Raras. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras. Instituto de Salud Carlos III (CB06/07/1009; CIBERER-ISCIII), Madrid, Spain., Notario L; Centro Nacional de Microbiología. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain., Melero-Fernández de Mera RM; Unidad de Tumores Sólidos Infantiles. Instituto de Investigación de Enfermedades Raras. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras. Instituto de Salud Carlos III (CB06/07/1009; CIBERER-ISCIII), Madrid, Spain.; Facultad HM de Ciencias de la Salud. Universidad Camilo José Cela. Instituto de Investigación Sanitaria HM Hospitales, Madrid, Spain., Alonso J; Unidad de Tumores Sólidos Infantiles. Instituto de Investigación de Enfermedades Raras. Instituto de Salud Carlos III. Majadahonda, Madrid, Spain. fjalonso@isciii.es.; Centro de Investigación Biomédica en Red de Enfermedades Raras. Instituto de Salud Carlos III (CB06/07/1009; CIBERER-ISCIII), Madrid, Spain. fjalonso@isciii.es.

Journal Article , 2025

Cytoplasmic accumulation of a splice variant of hnRNPA2/B1 contributes to FUS-associated toxicity in a mouse model of ALS.

Rossi S; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy., Milani M; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy.; Department of Biology, University of Rome Tor Vergata, Rome, Italy.; PhD Program in Cellular and Molecular Biology, University of Rome Tor Vergata, Rome, Italy., Della Valle I; Department of Biology, University of Rome Tor Vergata, Rome, Italy.; PhD Program in Cellular and Molecular Biology, University of Rome Tor Vergata, Rome, Italy., Bisegna S; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy., Durante V; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy., Addesse M; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy.; Department of Biology, University of Rome Tor Vergata, Rome, Italy., D'Avorio E; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy.; Department of Biology, University of Rome Tor Vergata, Rome, Italy., Di Salvio M; Institute of Biology and Molecular Pathology, IBPM-CNR, Rome, Italy., Serafino A; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy., Cestra G; Institute of Biology and Molecular Pathology, IBPM-CNR, Rome, Italy.; IRCCS San Raffaele, Rome, Italy., Apolloni S; Department of Biology, University of Rome Tor Vergata, Rome, Italy. Savina.Apolloni@uniroma2.it., D'Ambrosi N; Department of Biology, University of Rome Tor Vergata, Rome, Italy. nadia.dambrosi@uniroma2.it., Cozzolino M; Institute of Translational Pharmacology, IFT-CNR, Rome, Italy. mauro.cozzolino@ift.cnr.it.

Journal Article , 2025