Search Results - "SRC"

Restoration of pp60 ^Src Re-Establishes Electron Transport Chain Complex I Activity in Pulmonary Hypertensive Endothelial Cells.

Yegambaram M; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA., Pokharel MD; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA., Sun X; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA., Lu Q; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA., Soto J; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA., Aggarwal S; Department of Cellular Biology & Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA., Maltepe E; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA., Fineman JR; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA.; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA., Wang T; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA.; Department of Environmental Health Sciences, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL 33199, USA., Black SM; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port St. Lucie, FL 34987-2352, USA.; Department of Cellular Biology & Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.; Department of Environmental Health Sciences, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL 33199, USA.

Journal Article , 2025

Lipid-driven Src self-association modulates its transformation capacity.

Mohammad IL; View item Biomolecular NMR Laboratory, Department of Inorganic and Organic Chemistry, Universitat de Barcelona (UB), Barcelona, Spain., Giannotti MI; View item Nanoprobes and Nanoswitches Group, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; View item Materials Science and Physical Chemistry Department, IQTCUB, Universitat de Barcelona (UB), Barcelona, Spain., Fourgous E; CNRS UMR5237, University of Montpellier, CRBM, Montpellier, France.; Equipe Labellisée Ligue Contre le Cancer, CRBM, University of Montpellier, CNRS, Montpellier, France., Boublik Y; CNRS UMR5237, University of Montpellier, CRBM, Montpellier, France.; Equipe Labellisée Ligue Contre le Cancer, CRBM, University of Montpellier, CNRS, Montpellier, France., Fernández A; View item Biomolecular NMR Laboratory, Department of Inorganic and Organic Chemistry, Universitat de Barcelona (UB), Barcelona, Spain., Le Roux AL; View item Nanoprobes and Nanoswitches Group, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Sirvent A; CNRS UMR5237, University of Montpellier, CRBM, Montpellier, France.; Equipe Labellisée Ligue Contre le Cancer, CRBM, University of Montpellier, CNRS, Montpellier, France., Taulés M; View item Centres Científics i Tecnològics (CCiTUB), Universitat de Barcelona (UB), Barcelona, Spain., Roche S; CNRS UMR5237, University of Montpellier, CRBM, Montpellier, France Serge.Roche@crbm.cnrs.fr.; Equipe Labellisée Ligue Contre le Cancer, CRBM, University of Montpellier, CNRS, Montpellier, France., Pons M; View item Biomolecular NMR Laboratory, Department of Inorganic and Organic Chemistry, Universitat de Barcelona (UB), Barcelona, Spain mpons@ub.edu.

Journal Article , 2025

Interaction of T-cell-specific adapter protein with Src- and Tec-family kinases.

Huszenicza Z; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Gilmour BC; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Koll L; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Kjelstrup H; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Chan H; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Sundvold V; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Granum S; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Spurkland A; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Journal Article , 2024

Role of the GRP78-c-Src signaling pathway on osteoblast differentiation of periodontal ligament fibroblasts induced by cyclic mechanical stretch.

Hu J; Public Experimental Platform, College of Life Science Institute, Jinzhou Medical University, Jinzhou 121001, China., Cui Z; Center of Oral Implantology, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China., Huang K; Dept. of Orthodontics, Affiliated Stomatological Hospital, Jinzhou Medical University, Jinzhou 121001, China., Su R; College of Basic Medical Science, Jinzhou Medical University, Jinzhou 121001, China., Zhao S; Public Experimental Platform, College of Life Science Institute, Jinzhou Medical University, Jinzhou 121001, China.

Journal Article , 2024

Hantaan virus activates Src family kinase and induces endothelial cell hyperpermeability via the TLR4/TRAF6 pathway.

Wang X; Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China., Shen H; Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China., Du H; Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China., Jiang H; Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China., Wang P; Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China., Zhang Y

Journal Article , 2025

Compound FLZ attenuates neuroinflammation through inhibiting Src/PTEN/Akt signaling pathway.

Li FF; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Zheng YP; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Li G; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Yang Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Ma JW; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Zang CX; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Tao D; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Li L; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Bao XQ; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Zhang D; State Key Laboratory of Bioactive Substance and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Journal Article , 2025

Advancing Src kinase inhibition: From structural design to therapeutic innovation - A comprehensive review.

Su Y; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China., Zhu K; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China., Wang J; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China., Liu B; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China., Chang Y; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China., Chang D; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China; TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Chengdu, 610072, China. Electronic address: changdg@cdutcm.edu.cn., You Y; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China; TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Chengdu, 610072, China. Electronic address: yyd110@163.com.

Journal Article; Review , 2025

Suppression of SRC protein kinase activity alleviates the severity of aganglionosis by impairing CAV1/FLNA expression.

Xu X; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China., Liu Y; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China., Lan M; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China., Liu F; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China., Xia H; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China., Zeng J; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.

Journal Article , 2025

IGF2BP3 Triggers STAT3 Pathway by Stabilizing SRC RNA in an m6A-Dependent Manner to Promote Lymphatic Metastasis in LUAD.

Ding J; Department of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; Key Laboratory of Radiation Oncology of Taizhou, Radiation Oncology Institute of Enze Medical Health Academy, Taizhou Hospital Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.; Department of Radiation Oncology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Wang X; Key Laboratory of Radiation Oncology of Taizhou, Radiation Oncology Institute of Enze Medical Health Academy, Taizhou Hospital Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.; Department of Radiation Oncology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Yang H; Key Laboratory of Radiation Oncology of Taizhou, Radiation Oncology Institute of Enze Medical Health Academy, Taizhou Hospital Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.; Department of Radiation Oncology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Zhang L; School of Laboratory Medicine, Ningxia Medical University, Yinchuan, China., Ying Y; Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Pi W; Key Laboratory of Radiation Oncology of Taizhou, Radiation Oncology Institute of Enze Medical Health Academy, Taizhou Hospital Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.; Department of Radiation Oncology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Deng G; Key Laboratory of Radiation Oncology of Taizhou, Radiation Oncology Institute of Enze Medical Health Academy, Taizhou Hospital Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.; Department of Radiation Oncology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang, China., Zhu Y; Department of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Journal Article , 2025

LCN2 promotes focal adhesion formation and invasion by stimulating c-Src activation.

Choudhary BS; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India.; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India., Chaudhary N; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Khan BK; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India.; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India., Vijan A; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Mandal D; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Pilankar L; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Gawand S; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Uttankar P; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India.; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India., Sharma M; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Shivashankar A; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Doloi R; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Joshi N; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India., Das M; Molecular Immunology, Mazumdar Shaw Medical Foundation, 8th floor, Mazumdar Shaw Medical Centre, Narayana Health City, Bommasandra, Bangalore 560099, India.; Center for Precision Diagnostic and Therapeutic Research, India (CPDTRI), B-202, First Floor, Block 1, KSSIDC Complex, Electronic City Phase 1, Bengaluru 560100, Karnataka, India., Dalal SN; Cell and Tumour Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India.; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India.

Journal Article , 2025

Kaempferol targets Src to exert its chemopreventive effects on mammary tumorigenesis via regulation of the PI3K/AKT pathway.

Wang P; Laboratory Medicine Center, Sichuan Provincial Women's and Children's Hospital, Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu 610032, China., Ma Y; Department of Clinical Research, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610042, China., Rao X; Department of Clinical Research, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610042, China., Luo Q; Laboratory Medicine Center, Sichuan Provincial Women's and Children's Hospital, Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu 610032, China., Xiao X; Laboratory Medicine Center, Sichuan Provincial Women's and Children's Hospital, Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu 610032, China., Wang T; Department of Clinical Research, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610042, China. Electronic address: wangting8934@126.com., Long F; Laboratory Medicine Center, Sichuan Provincial Women's and Children's Hospital, Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu 610032, China. Electronic address: longfangyi1206@163.com.

Journal Article , 2025

Therapeutic potential of GNRHR analogs and SRC/FAK inhibitors to counteract tumor growth and metastasis in breast cancer.

Mondaca JM; Laboratorio de Transducción de Señales y Movimiento Celular, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina., Muñoz JMF; Departamento de Laboratorio de Salud Pública, Ministerio de Salud y Deportes, Gobierno de Mendoza, Mendoza, Argentina., Barraza GA; Laboratorio de Transducción de Señales y Movimiento Celular, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina., Vanderhoeven F; Laboratorio de Biología Tumoral, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina., Redondo AL; Laboratorio de Biología Tumoral, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina., Flamini MI; Laboratorio de Biología Tumoral, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina. Electronic address: mflamini@mendoza-conicet.gov.ar., Sanchez AM; Laboratorio de Transducción de Señales y Movimiento Celular, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina. Electronic address: amsanchez@mendoza-conicet.gov.ar.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Siglec6 CAR T cells suppressed progression of AML via inhibiting Siglec6 and SHP2 induced Src and ERK signaling activation.

Li Q; Department of Hematology, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Lin L; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Gao S; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Chen L; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Zhang Z; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Ma J; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Liu S; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China., Cao Z; Department of Hematology, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China., Zhao H; Department of Hematology, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China. hzhao02@tmu.edu.cn., Wang Y; Department of Hematology, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China. yfwang@tmu.edu.cn.; Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin, China. yfwang@tmu.edu.cn.

Journal Article , 2025

Taletrectinib promotes pyroptosis in colorectal carcinoma via SRC/AKT/mTOR axis inhibition.

Zhang T; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China., Zou Y; School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China., Zhang SH; School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China., Wang YY; School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China., He S; School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China., Yuan W; School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China., Yang M; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China., Liu T; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China., Deng SH; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China., Wu DM; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China., Xu Y; School of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China. yingxu825@126.com.

Journal Article , 2025

HIV-1 Nef activates proviral DNA transcription by recruiting Src kinase to phosphorylate host protein Nef-associated factor 1 to compromise its viral restrictive function.

Fan T-J; Pingyuan Laboratory, State Key Laboratory of Antiviral Drugs, Henan Normal University, Xinxiang, China.; Shanghai Sci-Tech Inno Center for Infection & Immunity, Shanghai, China., Xie C; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Graduate School of Guangzhou Medical University, Guangzhou, China., Li L; Pingyuan Laboratory, State Key Laboratory of Antiviral Drugs, Henan Normal University, Xinxiang, China., Jin X; Pingyuan Laboratory, State Key Laboratory of Antiviral Drugs, Henan Normal University, Xinxiang, China., Cui J; Shanghai Sci-Tech Inno Center for Infection & Immunity, Shanghai, China., Wang J-H; Pingyuan Laboratory, State Key Laboratory of Antiviral Drugs, Henan Normal University, Xinxiang, China.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

Journal Article , 2025

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development.

Wang Q; Department of Ophthalmology, Columbia University, New York, United States., Li H; Department of Ophthalmology, Columbia University, New York, United States., Mao Y; Department of Ophthalmology, Columbia University, New York, United States., Garg A; Department of Ophthalmology, Columbia University, New York, United States., Park ES; Department of Ophthalmology, Columbia University, New York, United States., Wu Y; Department of Ophthalmology, Columbia University, New York, United States., Chow A; Department of Ophthalmology, Columbia University, New York, United States., Peregrin J; Department of Ophthalmology, Columbia University, New York, United States., Zhang X; Department of Ophthalmology, Columbia University, New York, United States.; Department of Pathology and Cell Biology, Columbia University, New York, United States.

Journal Article , 2025

Macrophage Lyn Kinase Is a Sex-Specific Regulator of Post-Subarachnoid Hemorrhage Neuroinflammation.

Islam R; Cooper Medical School of Rowan University Camden NJ USA.; Department of Neurology Cooper University Health Care Camden NJ USA., Choudhary HH; Cooper Medical School of Rowan University Camden NJ USA., Zhang F; Cooper Medical School of Rowan University Camden NJ USA.; Department of Neurology Cooper University Health Care Camden NJ USA., Mehta H; Cooper Medical School of Rowan University Camden NJ USA.; Department of Neurology Cooper University Health Care Camden NJ USA., Yoshida J; Cooper Medical School of Rowan University Camden NJ USA., Thomas A; Cooper Medical School of Rowan University Camden NJ USA.; Department of Neurosurgery Cooper University Health Care Camden NJ USA., Hanafy K; Cooper Medical School of Rowan University Camden NJ USA.; Department of Neurology Cooper University Health Care Camden NJ USA.; Center for Neuroinflammation Cooper Medical School of Rowan University Camden NJ USA.

Journal Article , 2025

Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.

Li Q; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Zhou M; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Yang Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Jiang Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Chen C; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Hu E; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Chen J; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China., Wang D; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550014 Guiyang, PR China; Natural Products Research Center of Guizhou Province, 550014 Guiyang, PR China. Electronic address: wangdaoping@gmc.edu.cn.

Journal Article , 2025

Targeting Na,K-ATPase-Src signaling to normalize cerebral blood flow in a murine model of familial hemiplegic migraine.

Staehr C; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.; School of Clinical Medicine, University of Queensland, St Lucia, Qld, Australia., Guldbrandsen HØ; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Homilius C; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Johnsen LØ; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Postnov D; Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark., Pedersen TM; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Pierre S; Institute for Interdisciplinary Research, Marshall University, Huntington, USA., Sandow SL; School of Clinical Medicine, University of Queensland, St Lucia, Qld, Australia.; School of Health, University of the Sunshine Coast, Maroochydore, Qld, Australia., Matchkov VV; Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Journal Article , 2025

AXL and SRC in clear cell renal cell carcinoma: absence of mutations, rare alternative splicing events, but association of protein expression with poor prognosis.

Brada MD; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Karakulak T; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Schraml P; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Haberecker M; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Rutishauser D; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Ross JS; Foundation Medicine, Inc., Cambridge, MA, USA.; Department of Pathology, Upstate Medical University, Syracuse, NY, USA.; Department of Urology, Upstate Medical University, Syracuse, NY, USA.; Department of Medicine (Oncology), Upstate Medical University, Syracuse, NY, USA., Eberli D; Department of Urology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Moch H; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland.

Journal Article , 2025