Search Results - "Schlemm's Canal"

Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Primary and Secondary Open- and Closed-Angle Glaucoma.

Naftali Ben Haim, Liron^1,2 (AUTHOR), Yehezkeli, Veronika^1,2 (AUTHOR), Kratz, Assaf^3,4 (AUTHOR), Dar, Nimrod^1,2,4 (AUTHOR), Sharon, Tal^1,2,5 (AUTHOR), Harel, Gal^1,2 (AUTHOR), Burganski-Eliash, Zvia^2,5 (AUTHOR), Belkin, Avner^1,2,3 (AUTHOR) avner.belkin@gmail.com

Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2.

Mishra, Sarthak¹ (AUTHOR), Ipe, Ute¹ (AUTHOR), Nottebaum, Astrid F.¹ (AUTHOR), Peters, Kevin G.² (AUTHOR), Vestweber, Dietmar¹ (AUTHOR) vestweb@mpi-muenster.mpg.de

Semi-automated evaluation of trabecular meshwork and schlemm canal imaged with OCT in children with normal eyes vs. primary congenital glaucoma.

Wang, Bo¹ (AUTHOR) wang.bo@jhmi.edu, Gregston, Alden P.² (AUTHOR), Naithani, Rizul² (AUTHOR), Alvarez, Samuel³ (AUTHOR), Sigireddi, Rohini R.² (AUTHOR), Freedman, Sharon F.² (AUTHOR)

Anterior segment and Schlemm's canal alterations during the menstrual cycle in reproductive-age Turkish women.

Torun IM; Department of Ophthalmology, Medical Health Sciences University, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey. isilmerveaktas@hotmail.com., Dalkiliç HG; Department of Ophthalmology, Medical Health Sciences University, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey., Toplak G; Department of Ophthalmology, Medical Health Sciences University, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey., Sönmez M; Department of Ophthalmology, Medical Health Sciences University, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.

Journal Article , 2025

Time-Lapse Live-Cell Imaging Using Fluorescent Protein Sensors in Outflow Pathway Cells Under Fluid Flow Conditions

Shim, Myoung Sup^Aff4, Liton, Paloma B.^Aff4

Jakobs, Tatjana^Aff2, Liton, Paloma B.^Aff3, Walker, John M.^Aff1

Phacoemulsification combined with trabecular meshwork-Schlemm canal-based minimally invasive glaucoma surgery in primary angle-closure glaucoma: a systematic review and meta-analysis.

Fang Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, No. 7 Jinsui Road, Guangzhou, 510060, China., Song Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, No. 7 Jinsui Road, Guangzhou, 510060, China., Jin L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, No. 7 Jinsui Road, Guangzhou, 510060, China., Han Y; Department of Ophthalmology, University of California, San Francisco, CA, USA. ying.han@ucsf.edu., Zhang X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, No. 7 Jinsui Road, Guangzhou, 510060, China. zhangxl2@mail.sysu.edu.cn.

Journal Article; Systematic Review; Meta-Analysis , 2025

Relationship between Schlemm's canal incision length and the results of ab interno gonioscopy-assisted transluminal suture trabeculotomy.

Tanabe H; Department of Ophthalmology, Yokkaichi Digestive Disease Center, Yokkaichi, Mie, Japan. tennsyoudragon@icloud.com., Nakakura S; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Nishimura K; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Terao E; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Fujisawa Y; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Nagata Y; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Oogi S; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Adachi M; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan., Matsuya K; Department of Ophthalmology, Tsukazaki Hospital, Himeji, Hyogo, Japan.

Journal Article , 2025

Effect of the IL-6 trans-signaling pathway in the absence or presence of TGF-β2 on Schlemm's canal endothelial cells.

Urahashi M; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Fujimoto T; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: tomofuji@kumamoto-u.ac.jp., Inoue-Mochita M; Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan., Inoue T; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

Journal Article , 2025

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response.

Fang R; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States., Zhang P; Department of Mechanical Engineering, Northwestern University, Evanston, Illinois, United States., Kim D; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States., Kweon J; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States., Sun C; Department of Mechanical Engineering, Northwestern University, Evanston, Illinois, United States., Huang AS; Hamilton Glaucoma Center, The Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, California, United States., Zhang HF; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States.

Journal Article , 2025

Preliminary antifibrotic and vasoconstrictor effects of adrenaline in Schlemm's canal and suprachoroidal minimally invasive glaucoma surgery in primary open-angle glaucoma.

Luo J; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK.; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Fajardo-Sanchez J; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK.; Department of Ophthalmology, Guy's and St Thomas', NHS Foundation Trust, London, SE1 7EH, UK., Qin M; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK., Patel B; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK., Mahtani K; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK., Ho H; Department of Ophthalmology, Guy's and St Thomas', NHS Foundation Trust, London, SE1 7EH, UK., Yu-Wai-Man C; Faculty of Life Sciences & Medicine, King's College London, London, SE1 7EH, UK. cynthia.yu-wai-man@kcl.ac.uk.; Department of Ophthalmology, Guy's and St Thomas', NHS Foundation Trust, London, SE1 7EH, UK. cynthia.yu-wai-man@kcl.ac.uk.

Journal Article , 2025

In Vivo Assessment of the Pediatric Trabecular Meshwork, Schlemm Canal, and Iridocorneal Angle Using Overhead-Mounted Optical Coherence Tomography.

Wang B; From the Wilmer Eye Institute, Johns Hopkins Hospital (B.W.), Baltimore, Maryland; Department of Ophthalmology, Duke University Medical Center (B.W., R.N., S.A., T.G., S.F.F.), Durham, North Carolina, USA.. Electronic address: wang.bo@jhmi.edu., Naithani R; Department of Ophthalmology, Duke University Medical Center (B.W., R.N., S.A., T.G., S.F.F.), Durham, North Carolina, USA., Alvarez S; Department of Ophthalmology, Duke University Medical Center (B.W., R.N., S.A., T.G., S.F.F.), Durham, North Carolina, USA., Glaser T; Department of Ophthalmology, Duke University Medical Center (B.W., R.N., S.A., T.G., S.F.F.), Durham, North Carolina, USA., Freedman SF; Department of Ophthalmology, Duke University Medical Center (B.W., R.N., S.A., T.G., S.F.F.), Durham, North Carolina, USA.. Electronic address: sharon.freedman@duke.edu.

Journal Article , 2025

The Change of Ciliary Muscle-Trabecular Meshwork-Schlemm Canal Complex after Phacoemulsification using Swept-Source-Optical Coherence Tomography.

Li Z; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China., Wu X; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China.; Hangzhou Hospital of Traditional Chinese Medical, Hangzhou, China., Ji X; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China.; Shanghai Dongfang Hospital, Shanghai, China., Zhu Z; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China., Zhe N; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China., Zhao YE; Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, China.; Eye Hospital of Wenzhou Medical University Hangzhou Branch, Hangzhou, China.

Journal Article , 2025

Long-term efficacy and safety of ab externo canaloplasty in the Polish Caucasian population with open-angle glaucoma: A 3-year retrospective study.

Konopińska, Joanna¹ (AUTHOR) joannakonopinska@o2.pl, Gołaszewska, Kinga¹ (AUTHOR), Saeed, Emil¹ (AUTHOR)

Schlemm's canal-selective Tie2/TEK knockdown induces sustained ocular hypertension in adult mice.

Schwakopf J; Department of Neurobiology, University of Utah, Salt Lake City, UT, 84132, USA., Romero CO; Department of Neurobiology, University of Utah, Salt Lake City, UT, 84132, USA., Lopez NN; Department of Neurobiology, University of Utah, Salt Lake City, UT, 84132, USA., Millar JC; Department of Pharmacology and Neuroscience and North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA., Vetter ML; Department of Neurobiology, University of Utah, Salt Lake City, UT, 84132, USA., Bosco A; Department of Neurobiology, University of Utah, Salt Lake City, UT, 84132, USA. Electronic address: alejandra.bosco@neuro.utah.edu.

Journal Article , 2024

Effectiveness and biocompatibility of a novel Schlemm's canal microstent for glaucoma management.

Huang M; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Zhang Y; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Chen Z; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Liu C; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Wang J; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Feng X; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Cheng W; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Wu Q; Xinzheng Branch Zhengzhou Central Hospital, Public People's Hospital of Xinzheng, Xinzheng, China., Wang Y; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China., Liu Q; Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China. 439640104@qq.com.

Journal Article , 2024

Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.

Balasubramanian R; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States., Kizhatil K; Department of Ophthalmology and Visual Sciences, The Ohio State University Medical Center, Columbus, United States., Li T; Department of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, United States., Tolman N; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.; Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, United States., Bhandari A; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.; Neuroscience Graduate Program, University of Utah, Salt Lake City, United States., Clark G; Department of Ophthalmology and Visual Sciences, The Ohio State University Medical Center, Columbus, United States., Bupp-Chickering V; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States., Kelly RA; Department of Ophthalmology, Duke University, Durham, United States., Zhou S; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.; SUNY Downstate Health Sciences University, New York, United States., Peregrin J; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States., Simón M; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States., Montgomery C; Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States., Stamer WD; Department of Ophthalmology, Duke University, Durham, United States., Qian J; Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, United States., John SWM; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, United States.

Journal Article , 2024

The role of YAP/TAZ mechanosignaling in trabecular meshwork and Schlemm's canal cell dysfunction.

Ghosh R; Department of Ophthalmology and Visual Sciences, Center for Vision Research, SUNY Upstate Medical University, Syracuse, NY 13210, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Herberg S; Department of Ophthalmology and Visual Sciences, Center for Vision Research, SUNY Upstate Medical University, Syracuse, NY 13210, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA; Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA; BioInspired Institute, Syracuse University, Syracuse, NY 13244, USA; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA. Electronic address: herbergs@upstate.edu.

Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural , 2024

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats.

Xu L; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Glaucoma Research Institute of Wenzhou Medical University, Wenzhou, Zhejiang, China., Zhao Y; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Zhang X; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Gang X; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Han J; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Zhou T; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Qi B; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Song S; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China., Ren R; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Glaucoma Research Institute of Wenzhou Medical University, Wenzhou, Zhejiang, China., Liang Y; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou, Zhejiang, China.; The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Glaucoma Research Institute of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Journal Article , 2024

Glaucoma-Protective Human Single-Nucleotide Polymorphism in the Angpt2 Locus Increased ANGPT2 Expression and Schlemm Canal Area in Mice-Brief Report.

Kiyota N; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Onay T; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Leeaw P; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Liu P; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Deb DK; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Thomson BR; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago., Segrè AV; Department of Ophthalmology, Ocular Genomics Institute, Massachusetts Eye and Ear, Boston (A.V.S., J.L.W.).; Department of Ophthalmology, Harvard Medical School, Boston, MA (A.V.S., J.L.W.).; Broad Institute of Harvard and MIT, Cambridge, MA (A.V.S., J.L.W.)., Wiggs JL; Department of Ophthalmology, Ocular Genomics Institute, Massachusetts Eye and Ear, Boston (A.V.S., J.L.W.).; Department of Ophthalmology, Harvard Medical School, Boston, MA (A.V.S., J.L.W.).; Broad Institute of Harvard and MIT, Cambridge, MA (A.V.S., J.L.W.)., Quaggin SE; Feinberg Cardiovascular and Renal Research Institute (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.; Division of Nephrology and Hypertension (N.K., T.O., P. Leeaw, P. Liu, D.K.D., B.R.T., S.E.Q.), Northwestern University Feinberg School of Medicine, Chicago.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2024

Comparison of iris area, Schlemm's canal, and corneal tomography parameters in unaffected eyes with unilateral fuchs uveitis syndrome patients.

Balci, Sevcan¹, Bolac, Ruveyde¹ ruveydebolac@gmail.com, Turan-Vural, Ece¹