Search Results - "Shengyong Yang"

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

Xiaoning Qi, Lianhe Zhao, Chenyu Tian, Yueyue Li, Zhen-Lin Chen, Peipei Huo, Runsheng Chen, Xiaodong Liu, Baoping Wan, Shengyong Yang, Yi Zhao

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Correction to: TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways

Wenzhi Shen, Renle Du, Jun Li, Xiaohe Luo, Shuangtao Zhao, Antao Chang, Wei Zhou, Ruifang Gao, Dehong Luo, Juan Wang, Na Hao, Yanhua Liu, Yanan Chen, Yunping Luo, Peiqing Sun, Shengyong Yang, Na Luo, Rong Xiang

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Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7

Xinyi Zhou, Xiaoyu Yang, Shenzhen Huang, Guifeng Lin, Kexin Lei, Qian Wang, Weimin Lin, Hanwen Li, Xingying Qi, Dutmanee Seriwatanachai, Shengyong Yang, Bin Shao, Quan Yuan

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Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51

Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao

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An integrative pan-cancer bioinformatics analysis of MSRB1 and its association with tumor immune microenvironment, prognosis, and immunotherapy

Shanshan Jiang, Shengyong Yang, Zhengdan Gao, Chuan Yin, Mengmeng Zhang, Qian Wu, Yi Li

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A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Chong Huang, Huiping Shuai, Jingxin Qiao, Yuxin Hou, Rui Zeng, Anjie Xia, Lingwan Xie, Zhen Fang, Yueyue Li, Chaemin Yoon, Qiao Huang, Bingjie Hu, Jing You, Baoxue Quan, Xiu Zhao, Nihong Guo, Shiyu Zhang, Ronggang Ma, Jiahao Zhang, Yifei Wang, Ruicheng Yang, Shanshan Zhang, Jinshan Nan, Haixing Xu, Falu Wang, Jian Lei, Hin Chu, Shengyong Yang

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Non-classical ferroptosis inhibition by a small molecule targeting PHB2

Wei Yang, Bo Mu, Jing You, Chenyu Tian, Huachao Bin, Zhiqiang Xu, Liting Zhang, Ronggang Ma, Ming Wu, Guo Zhang, Chong Huang, Linli Li, Zhenhua Shao, Lunzhi Dai, Laurent Désaubry, Shengyong Yang

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Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor

Yueshan Li, Liting Zhang, Yifei Wang, Jun Zou, Ruicheng Yang, Xinling Luo, Chengyong Wu, Wei Yang, Chenyu Tian, Haixing Xu, Falu Wang, Xin Yang, Linli Li, Shengyong Yang

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HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

Nan Liu, Lifang Zhou, Guifeng Lin, Yun Hu, Yaoge Jiao, Yanhong Wang, Jingming Liu, Shengyong Yang, Shaohua Yao

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A New Type of Endometrial Cancer Models in Mice Revealing the Functional Roles of Genetic Drivers and Exploring their Susceptibilities

Jingyao Chen, Siqi Dai, Lei Zhao, Yiman Peng, Chongen Sun, Hongling Peng, Qian Zhong, Yuan Quan, Yue Li, Xuelan Chen, Xiangyu Pan, Ailing Zhong, Manli Wang, Mengsha Zhang, Shengyong Yang, You Lu, Zhong Lian, Yu Liu, Shengtao Zhou, Zhengyu Li, Feifei Na, Chong Chen

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Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B

Na Sang, Xi Zhong, Kun Gou, Huan Liu, Jing Xu, Yang Zhou, Xia Zhou, Yuanzhi Liu, Zhiqian Chen, Yue Zhou, Yan Li, Lei Tao, Na Su, Lingyun Zhou, Jiahao Qiu, Xinyu Yang, Zeping Zuo, Li Fu, Jingyao Zhang, Dan Li, Cong Li, Qingxiang Sun, Jian Lei, Rui Li, Shengyong Yang, Xiaobo Cen, Yinglan Zhao

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Small molecules in targeted cancer therapy: advances, challenges, and future perspectives

Lei Zhong, Yueshan Li, Liang Xiong, Wenjing Wang, Ming Wu, Ting Yuan, Wei Yang, Chenyu Tian, Zhuang Miao, Tianqi Wang, Shengyong Yang

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Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

Wei Yan, Lin Cheng, Wei Wang, Chao Wu, Xin Yang, Xiaozhe Du, Liang Ma, Shiqian Qi, Yuquan Wei, Zhiliang Lu, Shengyong Yang, Zhenhua Shao

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Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections

Rui Zhang, Xiaohua Jiang, Jingxin Qiao, Zeng Wang, Aiping Tong, Jinliang Yang, Shengyong Yang, Li Yang

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Novel CDKs inhibitors for the treatment of solid tumour by simultaneously regulating the cell cycle and transcription control

Xin Wang, Kaiyuan Deng, Cheng Wang, Yao Li, Tianqi Wang, Zhi Huang, Yakun Ma, Peiqing Sun, Yi Shi, Shengyong Yang, Yan Fan, Rong Xiang

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Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway

Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang

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Structural and Functional Insights into an Archaeal Lipid Synthase

Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng

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Structural and Functional Insights into an Archaeal Lipid Synthase

Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng

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Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer

Wen Peng, Huaqing Zhang, Shisheng Tan, Yan Li, Yang Zhou, Liang Wang, Chunqi Liu, Qiu Li, Xiaobo Cen, Shengyong Yang, Yinglan Zhao

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SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines

Wei Yan, Tao Yang, Jianhong Yang, Taijin Wang, Yamei Yu, Yuxi Wang, Qiang Chen, Peng Bai, Dan Li, Haoyu Ye, Qiang Qiu, Yongzhao Zhou, Yiguo Hu, Shengyong Yang, Yuquan Wei, Weimin Li, Lijuan Chen

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