Search Results - "Temme JS"

In vitro selection of cyclized, glycosylated peptide antigens that tightly bind HIV high mannose patch antibodies.

Bailey JK, Horiya S, Neralkar M, Horvath V, Nakamoto K, Temme JS, Turra RJ, Krauss IJ

Journal Article; Preprint , 2025

Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1.

Orfanoudaki M; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Krumpe LRH; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Shenoy SR; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Wilson J; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Guszczynski T; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Henrich CJ; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Molina-Molina E; IrsiCaixa, Germans Trias i Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain., Erkizia I; IrsiCaixa, Germans Trias i Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain., Blanco J; IrsiCaixa, Germans Trias i Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain; Department of Infectious Diseases and Immunity, Centre for Health and Social Care Research (CESS), Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain; CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain., Izquierdo-Useros N; IrsiCaixa, Germans Trias i Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain; CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain., Montiero F; Embrapa Genetic Resources and Biotechnology National Institute of Science and Technology in Synthetic Biology, Brasília, Brazil., Tanuri A; Embrapa Genetic Resources and Biotechnology National Institute of Science and Technology in Synthetic Biology, Brasília, Brazil., Rech E; Embrapa Genetic Resources and Biotechnology National Institute of Science and Technology in Synthetic Biology, Brasília, Brazil., O'Keefe BR; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA; Natural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, Maryland, USA. Electronic address: okeefeba@mail.nih.gov.

Journal Article , 2025

Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics.

Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Tan Z; Department of Chemistry, Michigan State University, 578 S Shaw Lane, East Lansing, MI 48824, USA; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA., Li M; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Yang M; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Wlodawer A; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Huang X; Department of Chemistry, Michigan State University, 578 S Shaw Lane, East Lansing, MI 48824, USA; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA., Schneekloth JS Jr; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. Electronic address: gildersj@mail.nih.gov.

Journal Article , 2024

Anti-glycan monoclonal antibodies: Basic research and clinical applications.

Gillmann KM; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Marglous S; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Brown CE; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA. Electronic address: gildersj@mail.nih.gov.

Journal Article; Review , 2023

Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies.

Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Crainic JA; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Walker LM; Adimab LLC, Lebanon, New Hampshire, USA; Adagio Therapeutics, Inc, Waltham, Massachusetts, USA., Yang W; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan, USA., Tan Z; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan, USA., Huang X; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan, USA; Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan, USA., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA. Electronic address: gildersj@mail.nih.gov.

Journal Article; Research Support, N.I.H., Intramural , 2022

Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O -GalNAcylation in Numerous Human Tissues and Cell Lines.

Xia L; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Bellomo TR; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Gibadullin R; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Congdon MD; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Edmondson EF; Molecular Histopathology Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States., Li M; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States.; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States., Wlodawer A; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Li C; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Patel P; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Butcher D; Molecular Histopathology Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States.

Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S. , 2022

Selective Recognition of Carbohydrate Antigens by Germline Antibodies Isolated from AID Knockout Mice.

DeLaitsch AT; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Pridgen JR; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Tytla A; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Peach ML; Basic Science Program, Chemical Biology Laboratory, Leidos Biomedical Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States., Hu R; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Farnsworth DW; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., McMillan AK; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Flanagan N; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Nicklaus MC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States.

Journal Article; Research Support, N.I.H., Intramural , 2022

Anti-glycan antibodies: roles in human disease.

Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, U.S.A., Butler DL; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, U.S.A., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, U.S.A.

Journal Article; Review , 2021

The Impact of Sustained Immunization Regimens on the Antibody Response to Oligomannose Glycans.

Nguyen DN; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Redman RL; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Horiya S; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Bailey JK; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Xu B; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Stanfield RL; Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Temme JS; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States., Wang S; Department of Biology, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Rodal AA; Department of Biology, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States., Wilson IA; Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Krauss IJ; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States.

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. , 2020

Factors contributing to variability of glycan microarray binding profiles.

Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. gildersj@mail.nih.gov., Campbell CT, Gildersleeve JC

Journal Article; Research Support, N.I.H., Intramural , 2019

Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog.

Morehouse BR; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Kumar RP; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Matos JO; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Yu Q; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Bannister A; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Malik K; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Temme JS; Department of Chemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Krauss IJ; Department of Chemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States., Oprian DD; Department of Biochemistry , Brandeis University , 415 South Street , Waltham , Massachusetts 02454 , United States.

Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. , 2019

A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide.

Trabbic KR; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Whalen K; Rockland Immunochemicals Inc., Limerick, PA, 19464, USA., Abarca-Heideman K; Rockland Immunochemicals Inc., Limerick, PA, 19464, USA., Xia L; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Temme JS; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Edmondson EF; Pathology and Histotechnology Lab, Leidos Biomedical Research Inc., Frederick, MD, USA., Gildersleeve JC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Barchi JJ Jr; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA. barchij@mail.nih.gov.

Journal Article; Research Support, N.I.H., Extramural , 2019

Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.

Nguyen DN; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Xu B; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Stanfield RL; Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Bailey JK; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Horiya S; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Temme JS; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States., Leon DR; Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts 02215, United States., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States., Costello CE; Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts 02215, United States., Wilson IA; Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Krauss IJ; Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, United States.

Journal Article , 2019

Zirconium Metal-Organic Frameworks Assembled from Pd and Pt P ^N N ^N P Pincer Complexes: Synthesis, Postsynthetic Modification, and Lewis Acid Catalysis.

Reiner BR, Mucha NT, Rothstein A, Temme JS, Duan P, Schmidt-Rohr K, Foxman BM, Wade CR; Department of Chemistry , Brandeis University , 415 South Street MS 015 , Waltham , Massachusetts 02453 , United States.

Journal Article , 2018

DNA display of folded RNA libraries enabling RNA-SELEX without reverse transcription.

MacPherson IS; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, 651 Ilalo St., Biosciences Building, Suite 325, Honolulu, Hawaii 96813-5525, USA. iain.macpherson@hawaii.edu and Department of Chemistry, Brandeis University, 415 South St. MS 015, Waltham, MA 02454-9110, USA. kraussi@brandeis.edu., Temme JS; Department of Chemistry, Brandeis University, 415 South St. MS 015, Waltham, MA 02454-9110, USA. kraussi@brandeis.edu., Krauss IJ; Department of Chemistry, Brandeis University, 415 South St. MS 015, Waltham, MA 02454-9110, USA. kraussi@brandeis.edu.

Journal Article , 2017

Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12.

Horiya S; Department of Chemistry, Brandeis University , Waltham, Massachusetts 02454-9110, United States., Bailey JK, Temme JS, Guillen Schlippe YV, Krauss IJ

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2014

High temperature SELMA: evolution of DNA-supported oligomannose clusters which are tightly recognized by HIV bnAb 2G12.

Temme JS; Department of Chemistry, Brandeis University , Waltham, Massachusetts, 02454-9110, United States., MacPherson IS, DeCourcey JF, Krauss IJ

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2014

Directed evolution of 2G12-targeted nonamannose glycoclusters by SELMA.

Temme JS; Department of Chemistry, Brandeis University, 415 South St., Waltham, MA 02454 (USA)., Drzyzga MG, MacPherson IS, Krauss IJ

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2013

Multivalent glycocluster design through directed evolution.

MacPherson IS; Department of Chemistry, Brandeis University, 415 South St., Waltham, MA 02454, USA., Temme JS, Habeshian S, Felczak K, Pankiewicz K, Hedstrom L, Krauss IJ

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't , 2011