Sökresultat - "Transdifferentiation"

Dynamics of Cell Fate Decisions during Chemically Induced Multi-Lineage Trans-Differentiation at Single-Cell Level.

E W; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Fei L; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Wang J; Liangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, China., Wang X; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Wang R; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Wang X; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Zhang P; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Chen J; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Wu J; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Jiang M; Liangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, China., Huang D; School of Medicine, Tsinghua University, Beijing, 100191, China., Jia D; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China., Guo G; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China.; Liangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, China., Han X; Bone Marrow Transplantation Center of the First Affiliated Hospital, and Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, China.; Zhejiang Key Laboratory of Multi-omics Precision Diagnosis and Treatment of Liver Diseases, Hangzhou, Zhejiang, 310000, China.

Journal Article , 2025

5-HT promotes pancreatic α-to-β cell transdifferentiation.

Liu N; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Liu T; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Alim N; Department of Pediatrics, Tianjin Medical University General Hospital, Tianjin 300052, PR China., Zou J; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Hu X; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Zhang B; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Liu F; Department of Pediatrics, Tianjin Medical University General Hospital, Tianjin 300052, PR China., Ding X; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Sun P; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China., Wang S; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China; Tianjin Key Laboratory for Organ Transplantation, Tianjin First Central Hospital, Tianjin 300192, PR China; School of Medicine, Nankai University, Tianjin 300071, PR China., Zhang L; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Institute of Acute Abdominal Diseases, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, PR China. Electronic address: lanqiuzhang@126.com., Zheng R; Department of Pediatrics, Tianjin Medical University General Hospital, Tianjin 300052, PR China. Electronic address: rzheng@tmu.edu.cn., Liang R; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, PR China; NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Tianjin 300384, PR China. Electronic address: liangrui@nankai.edu.cn.

Journal Article , 2025

Transdifferentiation of Hairy Cell Leukemia to Lytic and Mass-Producing Histiocytic Sarcoma: A Novel Head and Neck Example and Review of the Literature.

Davies AJ; Oral and Maxillofacial Surgery, University of the Pacific Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA. adavies@pacific.edu., Daneshpajouhnejad P; Department of Pathology, Stanford Hospital, Palo Alto, USA., Patwardhan M; Oral and Maxillofacial Surgeon, Private Practice California, Huntington Beach, USA., Xu Z; University of the Pacific Arthur A. Dugoni School of Dentistry, San Francisco, USA., Cox DP; Oral and Maxillofacial Surgery, University of the Pacific Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA.

Journal Article; Case Reports; Review , 2025

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation.

Wang Y; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Xue H; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Zhu X; The First Affiliated Hospital of Jinan University, First Clinical Medical College, Jinan University, Guangzhou, 510632, P. R. China., Lin D; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Chen Z; The First Affiliated Hospital of Jinan University, First Clinical Medical College, Jinan University, Guangzhou, 510632, P. R. China., Dong X; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Chen J; Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China., Shi M; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Ni Y; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada.; Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China., Cao J; Department of Cell and Systems Biology, University of Toronto, Toronto, M5S 3G5, Canada., Wu R; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Kang C; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Pang X; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada., Crea F; Cancer Research Group, School of Life Health and Chemical Sciences, The Open University, Milton Keynes, MK7 6AA, UK., Lin YY; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada., Collins CC; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada., Gleave ME; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada., Parolia A; Michigan Center for Translational Pathology, Department of Urology, University of Michigan Medical School, Rogel Cancer Center, University of Michigan Hospital, Ann Arbor, 48109, USA., Chinnaiyan A; Michigan Center for Translational Pathology, Department of Urology, University of Michigan Medical School, Rogel Cancer Center, University of Michigan Hospital, Ann Arbor, 48109, USA., Ong CJ; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada., Wang Y; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, V5Z 1M9, Canada.; Vancouver Prostate Centre, Vancouver, V6H 3Z6, Canada.; Department of Experimental Therapeutics, BC Cancer, Vancouver, V5Z 1L3, Canada.

Journal Article , 2025

Foxo1 directs the transdifferentiation of mouse Sertoli cells into granulosa-like cells.

Chen J; Department of Cell Biology, Zunyi Medical University, Zunyi, Guizhou 563000, China., Cen C; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Wang M; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Qin S; Lin He's Academician Workstation of New Medicine and Clinical Translation, Jining Medical University, Jining, Shandong 272000, China., Liu B; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Shen Z; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Cui X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Hou X; Department of Cell Biology, Zunyi Medical University, Zunyi, Guizhou 563000, China. Electronic address: hxh19801122@163.com., Gao F; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: gaof@ioz.ac.cn., Chen M; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: chenmin@ioz.ac.cn.

Journal Article , 2025

Alzheimer's disease as an auto-innate immune pathology with potential cell trans-differentiation and enhanced trained immunity in 3xTg-AD mouse model.

Saaoud F; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Liu L; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Xu K; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Lu Y; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Shao Y; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Ben Issa M; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Jiang X; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA.; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Wang X; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Liu X; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Autieri M; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA., Wu S; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Wei J; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Yu J; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Bouchareb R; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Gillespie A; Section of Nephrology, Hypertension, and Kidney Transplantation, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Luo JJ; Department of Neurology, Temple University, Philadelphia, PA, USA., Martinez L; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, USA., Vazquez-Padron R; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, USA., Sun J; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Zhao H; Department of Biomedical Education and Data Sciences, Temple University, Philadelphia, PA, USA., Wang H; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Pratico D; Alzheimer's Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Yang X; Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, USA.; Lemole Center for Integrated Lymphatics and Vascular Research, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

Journal Article , 2025

Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer.

Wang H; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Zhang S; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China., Pan Q; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.; Jinfeng Laboratory, Chongqing, China., Guo J; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Li N; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.; Jinfeng Laboratory, Chongqing, China., Chen L; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China., Xu J; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China., Zhou J; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China., Gu Y; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Wang X; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Zhang G; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Lian Y; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Zhang W; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Lin N; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Jin Z; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Zang Y; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Lan W; Department of Urology, Daping Hospital, Army Medical University, Chongqing, China., Cheng X; Jinfeng Laboratory, Chongqing, China., Tan M; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China., Chen FX; Fudan University Shanghai Cancer Center, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, China., Jiang J; Department of Urology, Daping Hospital, Army Medical University, Chongqing, China., Liu Q; Department of Urology, Daping Hospital, Army Medical University, Chongqing, China. liuqiuli900827@163.com., Zheng M; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. myzheng@simm.ac.cn., Qin J; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. qinjun@sibs.ac.cn.; Jinfeng Laboratory, Chongqing, China. qinjun@sibs.ac.cn.

Journal Article , 2025

24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting T H 17 pathogenicity and transdifferentiation.

Zhu C; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Boucheron N; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Al-Rubaye O; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Chung BK; Department of Transplantation Medicine, Clinic of Surgery and Specialized Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway., Thorbjørnsen LW; Department of Transplantation Medicine, Clinic of Surgery and Specialized Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway., Köcher T; Vienna BioCenter Core Facilities, Metabolomics, Vienna BioCenter, Vienna, Austria., Schuster M; Biomedical Sequencing Facility, Cemm, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Claudel T; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Halilbasic E; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Kunczer V; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Muscate F; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Cavanagh LL; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Waltenberger D; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Lercher A; Cemm, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Ohradanova-Repic A; Institute for Hygiene and Applied Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Schatzlmaier P; Institute for Hygiene and Applied Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Stojakovic T; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Bergthaler A; Cemm, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute for Hygiene and Applied Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Stockinger H; Institute for Hygiene and Applied Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bock C; Biomedical Sequencing Facility, Cemm, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Kenner L; Division of Experimental and Translational Pathology, Department of Pathology, Medical University of Vienna, Vienna, Austria.; Unit of Laboratory Animal Pathology, Department for Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria., Karlsen TH; Department of Transplantation Medicine, Clinic of Surgery and Specialized Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway., Ellmeier W; Institute of Immunology, Center for Pathophysiology Infectiology and Immunology, Medical University of Vienna, Vienna, Austria michael.trauner@meduniwien.ac.at wilfried.ellmeier@meduniwien.ac.at., Trauner M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria michael.trauner@meduniwien.ac.at wilfried.ellmeier@meduniwien.ac.at.

Journal Article , 2025

Macrophages Transdifferentiate Into Myofibroblasts During Ocular Surface Inflammation.

Sinha NR; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Pulimamidi VK; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Folorunso OS; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Xi L; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Dana NK; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Bolleddula J; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Cho WJ; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Mittal SK; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA., Chauhan SK; Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.

Journal Article , 2025

Delivery of bone marrow mesenchymal stem cell-derived exosomes into fibroblasts attenuates intestinal fibrosis by weakening its transdifferentiation via the CCN2-TGF-β axis.

Ling F; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277, Jiefang Avenue, Wuhan, 430022, Hubei province, China.; Department of Gastroenterology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China., Yang W; Department of Gastroenterology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China., Yuan M; Pediatric Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Chen Y; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277, Jiefang Avenue, Wuhan, 430022, Hubei province, China., Li J; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277, Jiefang Avenue, Wuhan, 430022, Hubei province, China., Wu J; Department of Gastroenterology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China., Zhu L; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277, Jiefang Avenue, Wuhan, 430022, Hubei province, China. zhuliangru@hust.edu.cn.

Journal Article , 2025

Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation.

Teng M; Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Guo J; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Xu X; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Ci X; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Mo Y; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Kohen Y; Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Ni Z; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Chen S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Guo WY; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Bakht M; Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA., Ku S; Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA., Sigouros M; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Luo W; Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China., Macarios CM; Department of Chemistry, University of Toronto, Toronto, ON, Canada., Xia Z; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada., Chen M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Ul Haq S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Yang W; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Berlin A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., van der Kwast T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Ellis L; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Zoubeidi A; Vancouver Prostate Centre, Vancouver, BC, Canada; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada., Zheng G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Ming J; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Wang Y; Vancouver Prostate Centre, Vancouver, BC, Canada; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada., Cui H; Department of Chemistry, University of Toronto, Toronto, ON, Canada., Lok BH; Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada., Raught B; Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Beltran H; Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA. Electronic address: himisha_beltran@dfci.harvard.edu., Qin J; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. Electronic address: qinjun@sibs.ac.cn., He HH; Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. Electronic address: hansen.he@uhn.ca.

Journal Article , 2025

Casz1 is required for both inner hair cell fate stabilization and outer hair cell survival.

Sun Y; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Ren M; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Zhang Y; Department of Otolaryngology-Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Li S; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Luo Z; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Sun S; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., He S; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Wang G; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Zhang D; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Mansour SL; Department of Human Genetics, University of Utah, Salt Lake City, UT, USA., Song L; Department of Otolaryngology-Head and Neck Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Liu Z; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.; Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai, China.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Combination of Epigallocatechin-3-Gallate and Tramiprosate Prevent Accumulation of Intracellular Aβ and Dysfunctional Autophagy-Lysosomal Pathway at Earliest Stage of Transdifferentiation of Mesenchymal Stromal Cells into PSEN1 E280A Cholinergic-like Neurons.

Soto-Mercado V; Neuroscience Research Group, Institute of Medical Research, Faculty of Medicine, University Research Headquarters, Calle 62#52-59, Building 1, Laboratory 411/412, Medellin 050010, Colombia., Mendivil-Perez M; Neuroscience Research Group, Faculty of Nursing, University Research Headquarters, Calle 62#52-59, Building 1, Laboratory 411/412, Medellin 050010, Colombia., Jimenez-Del-Rio M; Neuroscience Research Group, Institute of Medical Research, Faculty of Medicine, University Research Headquarters, Calle 62#52-59, Building 1, Laboratory 411/412, Medellin 050010, Colombia., Velez-Pardo C; Neuroscience Research Group, Institute of Medical Research, Faculty of Medicine, University Research Headquarters, Calle 62#52-59, Building 1, Laboratory 411/412, Medellin 050010, Colombia.

Journal Article , 2025

Effects of Verteporfin on Interstitial Fluid Flow-Induced Fibrotic Transdifferentiation of Human Tenon Fibroblasts.

Frömmichen J; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Bungert E; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Ströble J; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Gläser M; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Gottwald C; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Zeqiri K; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Reinhard T; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lübke J; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schlunck G; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wiedenmann CJ; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Journal Article , 2025

Conditional Overexpression of Net1 Enhances the Trans-Differentiation of Lgr5 ⁺ Progenitors into Hair Cells in the Neonatal Mouse Cochlea.

Lin Y; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Zhang Q; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Tong W; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Wang Y; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Wu L; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Xiao H; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Tang X; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Dai M; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Ye Z; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China., Chai R; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China.; Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Science, Beijing, China.; Department of Otolaryngology Head and Neck Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Zhang S; State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China.; Southeast University Shenzhen Research Institute, Shenzhen, China.

Journal Article , 2025

Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster.

Marcetteau J; Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal., Duarte P; Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal., Leitão AB; Fundação Champalimaud, Lisboa, Portugal. alexandre.leitao@research.fchampalimaud.org., Sucena É; Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal. jesucena@fc.ul.pt.; Departamento de Biologia Animal, Faculdade de Ciências, Universidade de Lisboa, Edifício C2, Campo Grande, 1749-016, Lisbon, Portugal. jesucena@fc.ul.pt.; cE3c: Centre for Ecology, Evolution and Environmental Changes, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016, Lisbon, Portugal. jesucena@fc.ul.pt.

Journal Article , 2025

Synergistic and antagonistic activities of IRF8 and FOS enhancer pairs during an immune-cell fate switch.

Klonizakis A; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain.; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 08005, Barcelona, Spain., Alcoverro-Bertran M; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain.; Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Spain., Massó P; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain., Thomas J; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain.; Faculty of Life Sciences and Medicine, King's College, WC2R 2LS, London, UK., de Andrés-Aguayo L; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain., Wei X; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain.; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 08005, Barcelona, Spain., Varamogianni-Mamatsi V; Institute of Pathology, University Medical Center Göttingen, 37075, Göttingen, Germany., Nikolaou C; Institute for Bioinnovation, Biomedical Sciences Research Centre 'Alexander Fleming', 16672, Vari, Greece. cnikolaou@fleming.gr., Graf T; Genome Biology Program, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain. thomas.graf@crg.eu.; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 08005, Barcelona, Spain. thomas.graf@crg.eu.

Journal Article , 2025

Copper Impedes Calcification of Human Aortic Vascular Smooth Muscle Cells Through Inhibition of Osteogenic Transdifferentiation and Promotion of Extracellular Matrix Stability.

Orlov I; University of Picardie Jules Verne, Amiens, France., Lenglet G; University of Picardie Jules Verne, Amiens, France., Avondo C; University of Picardie Jules Verne, Amiens, France., Beattie JH; The Rowett Institute, University of Aberdeen, Aberdeen, UK., Kamel S; University of Picardie Jules Verne, Amiens, France., Korichneva I; University of Picardie Jules Verne, Amiens, France.

Journal Article , 2025

Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.

Chou CC; Department of Biology, Stanford University, Stanford, CA, USA. cchou6@stanford.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. cchou6@stanford.edu., Vest R; Department of Chemical Engineering, Stanford University, Stanford, CA, USA.; Department of Neurology and Neurological Sciences and The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA.; Qinotto Inc., San Carlos, CA, USA., Prado MA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain., Wilson-Grady J; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Shibuya Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Moran-Losada P; Department of Neurology and Neurological Sciences and The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA.; Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, USA., Lee TT; Department of Biology, Stanford University, Stanford, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Luo J; Palo Alto Veterans Institute for Research Inc. (PAVIR), Palo Alto, CA, USA., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Kelly JW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA., Finley D; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Wernig M; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Wyss-Coray T; Department of Neurology and Neurological Sciences and The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA.; Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, USA., Frydman J; Department of Biology, Stanford University, Stanford, CA, USA. jfrydman@stanford.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. jfrydman@stanford.edu.; Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, USA. jfrydman@stanford.edu.; Department of Genetics, Stanford University, Stanford, CA, USA. jfrydman@stanford.edu.

Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural , 2025

Cell Reprogramming, Transdifferentiation, and Dedifferentiation Approaches for Heart Repair.

Almeida M; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Vital CM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Rodrigues MR; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Araújo BC; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.

Journal Article; Review , 2025