Search Results - "Unfolded protein response"

Targeting of the Hybrid Bamboo BDDnaJ by Pathogen Effector ApcE12 Regulates the Unfolded Protein Response.

Luo F; College of Forestry, Sichuan Agricultural University, Chengdu, China., Fang X; School of Life Sciences, Neijiang Normal University, Neijiang, China., Luo H; College of Forestry, Sichuan Agricultural University, Chengdu, China., Ye Z; College of Forestry, Sichuan Agricultural University, Chengdu, China., Liu S; College of Forestry, Sichuan Agricultural University, Chengdu, China., Zhao H; College of Forestry, Sichuan Agricultural University, Chengdu, China., Li S; College of Forestry, Sichuan Agricultural University, Chengdu, China., Li S; College of Forestry, Sichuan Agricultural University, Chengdu, China.; National Forestry and Grassland Administration Key Laboratory of Forest Resources Conservation and Ecological Safety on the Upper Reaches of the Yangtze River and Forestry Ecological Engineering in the Upper Reaches of the Yangtze River Key Laboratory of Sichuan Province, Chengdu, China.

Journal Article , 2025

Unraveling the crucial role of UPR pathway in rat brain development.

Jiang Y; Anhui Medical University, Hefei, China., Wang A; Department of Neurosurgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Zou N; The Second School of Clinical Medicine, Anhui Medical University, Hefei, China., Dai H; Anhui Medical University, Hefei, China., Shan R; Anhui Medical University, Hefei, China., Ren S; Anhui Medical University, Hefei, China., Jiang T; Department of Biochemistry & Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China. tongcuij@ahmu.edu.cn., Li N; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, China. nslinan@163.com.

Journal Article , 2025

IRE1α-mediated UPR activation in gastrointestinal cancers: Adaptive mechanisms and therapeutic potential.

Soumya VV; Department of Biochemistry, Amala Cancer Research Centre (Recognised Research Centre, University of Calicut), Thrissur - 680 555, Kerala, India., Jisna B; Department of Biochemistry, Amala Cancer Research Centre (Recognised Research Centre, University of Calicut), Thrissur - 680 555, Kerala, India., Anu D; Department of Biochemistry, Amala Cancer Research Centre (Recognised Research Centre, University of Calicut), Thrissur - 680 555, Kerala, India., Binoy CF; Research and Post Graduate Department of Zoology, St Thomas College (Autonomous), Thrissur - 680 001, Affiliated to University of Calicut, Kerala, India., Babu TD; Department of Biochemistry, Amala Cancer Research Centre (Recognised Research Centre, University of Calicut), Thrissur - 680 555, Kerala, India. Electronic address: babutd@amalaims.org.

Journal Article; Review , 2025

ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation.

Shapira G; Department of Cell and Developmental Biology, Faculty of Medical and Health Sciences, Sagol School of Neuroscience, Edmond J Safra Center for Bioinformatics, Tel Aviv University, Tel Aviv, 6997801, Israel., Karmon G; Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Adams Super Center for Brain Studies and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel., Hacohen-Kleiman G; Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Adams Super Center for Brain Studies and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel., Ganaiem M; Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Adams Super Center for Brain Studies and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel., Shazman S; Department of Mathematics and Computer Science, The Open University of Israel, Ra'anana, 4353701, Israel., Theotokis P; Department of Neurology, Laboratory of Experimental Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Grigoriadis N; Department of Neurology, Laboratory of Experimental Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Shomron N; Department of Cell and Developmental Biology, Faculty of Medical and Health Sciences, Sagol School of Neuroscience, Edmond J Safra Center for Bioinformatics, Tel Aviv University, Tel Aviv, 6997801, Israel., Gozes I; Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Adams Super Center for Brain Studies and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel. igozes@tauex.tau.ac.il.

Journal Article , 2025

Insight into Ca ²⁺ - inositol 1,4,5-trisphosphate receptor 2 (IP 3 R2)-mediated unfolded protein response and apoptosis in scallop Patinopecten yessoensis under high temperature stress.

Gu W; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China., Ma X; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China., Yang C; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China. Electronic address: yangchuanyan@dlou.edu.cn., Jiang D; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China., Fan H; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China., Wang L; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China., Song L; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian 116023, China. Electronic address: lshsong@dlou.edu.cn.

Journal Article , 2025

Unraveling the functional and molecular interplay between cellular senescence and the unfolded protein response.

Giroud J; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, University of Lille, Lille, France., Combémorel E; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, University of Lille, Lille, France., Pourtier A; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, University of Lille, Lille, France., Abbadie C; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, University of Lille, Lille, France., Pluquet O; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, University of Lille, Lille, France.

Journal Article; Review , 2025

HNF4A Regulated APEH Deficiency Promotes UPR Activation in Diabetic Kidney Disease.

Wang F; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Peng Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Liang L; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Ruan Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Yu S; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China.; Department of Intensive Care Medicine, Jinyang Hospital Affiliated of Guizhou Medical University, Guiyang Second People's Hospital, Guiyang, Guizhou Province, China., Mo X; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China.; Department of Intensive Care Medicine, Jinyang Hospital Affiliated of Guizhou Medical University, Guiyang Second People's Hospital, Guiyang, Guizhou Province, China., Tan W; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Xu X; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Jia J; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Peng J; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Yu X; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Chen Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Long C; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Li M; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Shi M; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Zhang F; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Xiao Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Liu L; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Zhou Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Zhang T; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Guo B; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China., Wang Y; Department of Pathophysiology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou Province, China.; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, Guizhou Province, China.

Journal Article , 2025

Unveiling the crosstalk between unfolded protein response and apoptosis in triclosan induced hepatotoxicity in Labeo rohita.

Trivedi A; Toxicogenomics Laboratory, Department of Animal Science, M.J.P. Rohilkhand University, Bareilly, 243006, India. abha14sep@gmail.com., Saxena V; Toxicogenomics Laboratory, Department of Animal Science, M.J.P. Rohilkhand University, Bareilly, 243006, India., Banaee M; Department of Environmental Sciences, Faculty of Natural Resources, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran., Bakhasha J; Toxicogenomics Laboratory, Department of Animal Science, M.J.P. Rohilkhand University, Bareilly, 243006, India., Arya N; Toxicogenomics Laboratory, Department of Animal Science, M.J.P. Rohilkhand University, Bareilly, 243006, India., Yadav KK; Department of Zoology, Government Degree College, Bakkha Kheda, Unnao, 209801, India., Rizzo MG; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy., Faggio C; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.; Department of Eco-Sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.

Journal Article , 2025

UPR ^mt alleviates bone cancer pain through the restoration of mitochondrial function.

Li D; Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China., Xie M; Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China., Zeng H; Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China., Yu J; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Xu R; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Wang Z; Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China., Huang Y; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. Electronic address: hyl199006@126.com., Yang Y; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. Electronic address: 05yangyan1987@163.com., Sun Y; Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: sunyue@nju.edu.cn.

Journal Article , 2025

P.1 and P.2 SARS-CoV-2 Brazilian variants activate the unfolded protein response with a time and pathway specificity.

de Morais Gomes V; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., Santos DM; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., Macedo-da-Silva J; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., Lazari LC; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., Machado RRG; Laboratory of Clinical and Molecular Virology, Department of Microbiology, ICB, University of São Paulo, Brazil., Dos Santos AF; Department of Biochemistry, Institute of Chemistry, University of São Paulo, Brazil., Araujo DB; Laboratory of Clinical and Molecular Virology, Department of Microbiology, ICB, University of São Paulo, Brazil., Coutinho JVP; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., Arini GS; Department of Biochemistry, Institute of Chemistry, University of São Paulo, Brazil., Angeli CB; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil., de Souza EE; Unit for Drug Discovery, Department of Parasitology, ICB, University of São Paulo, Brazil., Marques RF; Laboratory of Antigen Targeting for Dendritic Cells, Department of Parasitology, ICB, University of São Paulo, Brazil., Boscardin SB; Laboratory of Antigen Targeting for Dendritic Cells, Department of Parasitology, ICB, University of São Paulo, Brazil., Wrenger C; Unit for Drug Discovery, Department of Parasitology, ICB, University of São Paulo, Brazil., Marinho CRF; Laboratory of Experimental Immunoparasitology, Department of Parasitology, ICB, University of São Paulo, Brazil., Oliveira DBL; Laboratory of Clinical and Molecular Virology, Department of Microbiology, ICB, University of São Paulo, Brazil., Durigon EL; Laboratory of Clinical and Molecular Virology, Department of Microbiology, ICB, University of São Paulo, Brazil; Scientific Platform Pasteur USP, Sao Paulo, Brazil., Labriola L; Department of Biochemistry, Institute of Chemistry, University of São Paulo, Brazil., Rosa-Fernandes L; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil; Laboratory of Experimental Immunoparasitology, Department of Parasitology, ICB, University of São Paulo, Brazil; Centre for Motor Neuron Disease Research, Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, Sydney, Australia., Palmisano G; GlycoProteomics Laboratory, Department of Parasitology, ICB, University of São Paulo, Brazil; School of Natural Sciences, Macquarie University, Sydney, Australia. Electronic address: palmisano.gp@gmail.com.

Journal Article , 2025

Unraveling UPR-mediated intercellular crosstalk: Implications for immunotherapy resistance mechanisms.

Lu S; Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Provincial Key Laboratory of Pancreatic Disease, First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Key Laboratory of Frontier Medical Research on Cancer Metabolism, Hangzhou, China; Institute of Fundamental and Transdisciplinary Research, Zhejiang University, Hangzhou, China., Zhou Q; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao R; Department of Gynecological Radiotherapy, Zhejiang Cancer Hospital, Hangzhou, China., Xie L; Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address: xiel@srrsh.com., Cao WM; Department of Breast Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, China. Electronic address: caowm@zjcc.org.cn., Feng YX; Zhejiang Provincial Key Laboratory of Pancreatic Disease, First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Key Laboratory of Frontier Medical Research on Cancer Metabolism, Hangzhou, China; Institute of Fundamental and Transdisciplinary Research, Zhejiang University, Hangzhou, China. Electronic address: China.yxfeng@zju.edu.cn.

Journal Article; Review , 2025

A preliminary study on the regulation and impact of unfolded protein response on circadian genes in Litopenaeus vannamei.

Chen WY; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China., Yan ZY; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China., Shu-Chen; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China., Liu AN; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China., Miao YT; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China., Wang L; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China. Electronic address: wanglei@scnu.edu., Chen YH; Institute of Modern Aquaculture Science and Engineering (IMASE)/Guangdong-Macao Joint Laboratory for Aquaculture Breeding Development and Innovation/College of Life Science, South China Normal University, 510640, Guangzhou, 510631, PR China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519000, PR China. Electronic address: 20181024@m.scnu.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

CD40 Induces Unfolded Protein Response, Upregulation of VEGF, and Vascular Leakage in Diabetic Retinopathy.

Vos S; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Portillo JC; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Hubal A; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH.; Department of Pathology, Case Western Reserve University, Cleveland, OH., Bapputty R; Department of Pediatrics, Case Western Reserve University, Cleveland, OH., Pfaff A; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Aaron R; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Weng M; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Sun D; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH., Lu ZR; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH., Yu JS; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH., Subauste CS; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH.; Department of Pathology, Case Western Reserve University, Cleveland, OH.

Journal Article , 2025

The Role of ER Stress and the Unfolded Protein Response in Cancer.

Ghemrawi R; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates; rose.ghemrawi@aau.ac.ae.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates., Kremesh S; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates., Mousa WK; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.; College of Pharmacy, Mansoura University, Mansoura, Egypt., Khair M; Core Technology Platforms, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.

Journal Article; Review , 2025

Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH.

Goossen CJ; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Kufner A; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Dustin CM; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Al Ghouleh I; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Yuan S; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Straub AC; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Sembrat J; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine University of Pittsburgh, Pittsburgh, PA, 15261, USA., Baust JJ; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Gomez D; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Kračun D; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Balgrist University Hospital, University of Zurich, Zurich, Switzerland; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland. Electronic address: dkracun@ethz.ch., Pagano PJ; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address: pagano@pitt.edu.

Journal Article , 2025

p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy.

Trouvé P; Univ Brest, Inserm, EFS, UMR 1078, 22 Avenue Camille Desmoulins, F-29200 Brest, France., Férec C; Univ Brest, Inserm, EFS, UMR 1078, 22 Avenue Camille Desmoulins, F-29200 Brest, France.

Journal Article; Review , 2025

Spring viraemia of carp virus modulates the time-dependent unfolded protein response to facilitate viral replication.

Romero A; Instituto de Investigaciones Marinas Spanish National Research Council (CSIC), Vigo, Spain., Figueras A; Instituto de Investigaciones Marinas Spanish National Research Council (CSIC), Vigo, Spain., Novoa B; Instituto de Investigaciones Marinas Spanish National Research Council (CSIC), Vigo, Spain.

Journal Article , 2025

Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress.

Di Pede A; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Ko B; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., AlOkda A; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Tamez González AA; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Zhu S; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Van Raamsdonk JM; Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Intergrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.

Journal Article , 2025

Acute treadmill exercise induces mitochondrial unfolded protein response in skeletal muscle of male rats.

Turkel I; Department of Exercise and Sport Sciences, Faculty of Sport Sciences, Hacettepe University, Ankara, Turkey. Electronic address: ibrahimturkel@hacettepe.edu.tr., Kubat GB; Department of Mitochondria and Cellular Research, Gulhane Health Sciences Institute, University of Health Sciences, Ankara, Turkey; Gulhane Training and Research Hospital, University of Health Sciences, Ankara, Turkey. Electronic address: gokhanburcin.kubat@sbu.edu.tr., Fatsa T; Gulhane Health Sciences Institute, University of Health Sciences, Ankara, Turkey., Acet O; Department of Pathology, Gulhane Training and Research Hospital, Ankara, Turkey., Ozerklig B; Department of Exercise and Sport Sciences, Faculty of Sport Sciences, Hacettepe University, Ankara, Turkey; Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada; Children's Hospital Research Institute of Manitoba (CHRIM), Winnipeg, Canada., Yazgan B; Department of Medical Services and Techniques, Sabuncuoglu Serefeddin Health Services Vocational School, Amasya University, Amasya, Turkey., Simsek G; Department of Pathology, Gulhane Training and Research Hospital, Ankara, Turkey., Singh KK; Departments of Genetics, Dermatology and Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Kosar SN; Division of Exercise Nutrition and Metabolism, Faculty of Sport Sciences, Hacettepe University, Ankara, Turkey.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Control of Rhizobia Endosymbiosis by Coupling ER Expansion with Enhanced UPR.

Ren J; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang Q; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; Houji Laboratory in Shanxi Province, Academy of Agronomy, Shanxi Agricultural University, Taiyuan, 030031, China.; Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829, Cologne, Germany., Zhang X; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China., Cao Y; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wu J; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Tian J; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China., Yu Y; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China., Gong Q; State Key Laboratory of Microbial Metabolism & Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China., Kong Z; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.; Houji Laboratory in Shanxi Province, Academy of Agronomy, Shanxi Agricultural University, Taiyuan, 030031, China.

Journal Article , 2025