Search Results - "Vascular calcification"

Protein Kinase D Knockdown Alleviates Vascular Calcification Through P53-SLC7A11 Axis-Mediated Ferroptosis.

He W; Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.; JiNan Key Laboratory of Cardiovascular Disease, Shandong, China., Meng Y; JiNan Key Laboratory of Cardiovascular Disease, Shandong, China.; Shandong University, Shandong Provincial Hospital, Jinan, Shandong, China., Liu W; Shandong Dermatology Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China., Geng J; Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.; JiNan Key Laboratory of Cardiovascular Disease, Shandong, China.; Shandong University, Shandong Provincial Hospital, Jinan, Shandong, China.

Journal Article , 2025

GDF11 Alleviates Vascular Calcification in VitD 3 -Overloaded Mice Through Inhibition of Inflammatory NF-κB Signal.

Huang J; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, People's Republic of China., Liang Q; Department of Anesthesiology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, People's Republic of China., Ye Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, People's Republic of China., Lan Z; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, People's Republic of China., Chen A; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, People's Republic of China., Yan J; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, People's Republic of China., Lu L; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, People's Republic of China.

Journal Article , 2025

SREBP1 deficiency aggravates vascular calcification via iASPP-triggered ferroptosis of vascular smooth muscle cells.

Wu Y; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Yang B; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Sun H; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Cheng M; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Jin J; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Zhang D; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Chang L; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Zhang S; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Bai Y; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China., Xu J; Department of Nephrology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050011, People's Republic of China. 46400262@hebmu.edu.cn.; Hebei Key Laboratory of Vascular Calcification in Kidney Disease, Shijiazhuang, People's Republic of China. 46400262@hebmu.edu.cn.; Hebei Clinical Research Center for Chronic Kidney Disease, Shijiazhuang, People's Republic of China. 46400262@hebmu.edu.cn.

Journal Article , 2025

The bone-vascular axis: the link between osteoporosis and vascular calcification.

Sun Y; Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.; Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China., Huang D; Honghui Hospital, Xi'an Jiaotong University, Xi'an, People's Republic of China. huangdageng@xjtu.edu.cn., Zhang Y; Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China. zhangyan1114@xjtu.edu.cn.; Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China. zhangyan1114@xjtu.edu.cn.

Journal Article; Review , 2025

High-phosphate causes endothelial extracellular matrix calcification by inducing endothelial cell mesenchymal transition and osteoblastic differentiation.

Ciceri P; Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, Milan, Italy., Artioli L; Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, Milan, Italy., Molinaro M; Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, Milan, Italy., Falleni M; Department of Health Sciences, Division of Pathology, University of Milan, Milan, Italy., Tosi D; Department of Health Sciences, Division of Pathology, University of Milan, Milan, Italy., Martinelli C; Department of Health Sciences, Division of Pathology, University of Milan, Milan, Italy., Santo N; Bio-imaging Facility Unitech Nolimits, University of Milan, Milan, Italy., Rondinone O; Department of Health Sciences, Division of Medical Genetics, University of Milan, Milan, Italy., Miozzo M; Department of Health Sciences, Division of Medical Genetics, University of Milan, Milan, Italy., Bianchi P; Division of General and Robotic Surgery, Department of Health Sciences, San Paolo Hospital, University of Milan, Milan, Italy., Gianelli U; Department of Health Sciences, Division of Pathology, University of Milan, Milan, Italy., Fontana L; Department of Health Sciences, Division of Medical Genetics, University of Milan, Milan, Italy., Cozzolino M; Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, Milan, Italy.

Journal Article , 2025

METTL3-mediated N6-methyladenosine modification contributes to vascular calcification.

Li L; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, China; Department of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Chai Q; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, China; Department of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Guo C; Department of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Wei J; Department of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Qin Y; Department of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Liu H; Department of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, China; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, China. Electronic address: flysharon@zju.edu.cn., Lu Z; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, China; Department of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China. Electronic address: luzhaoyang@zju.edu.cn.

Journal Article , 2025

Honokiol attenuates oxidative stress and vascular calcification via the upregulation of heme oxygenase-1 in chronic kidney disease.

Xian X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Zhao X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Zhou X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Liu H; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Li C; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Wu X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Chen Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Ye K; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Yang H; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China., Li M; Department of Pathophysiology, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, China., Yan J; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China. Electronic address: yanjy790@smu.edu.cn., Zhang X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, China. Electronic address: zhangxiuli@smu.edu.cn.

Journal Article , 2025

Activation of TFEB protects against diabetic vascular calcification by improving autophagic flux and activating Nrf2 antioxidant system.

Sun XJ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Xiao SJ; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Ma WQ; Department of cardiovascular medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.; Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Jin H; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Ren LQ; Department of Geriatrics, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Yao YY; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Chen ZD; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Li XX; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Chen T; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China., Liu NF; Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China.

Journal Article , 2025

Balancing accuracy and cost in machine learning models for detecting medial vascular calcification in chronic kidney disease: a pilot study.

Bialonczyk U; Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland. ubialonczyk@ibib.waw.pl., Debowska M; Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland., Dai L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Qureshi AR; Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden., Bobrowski L; Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.; Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland., Soderberg M; Pathology, Clinical Pharmacology and Safety Sciences, AstraZeneca R&D, Gothenburg, Sweden., Lindholm B; Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden., Stenvinkel P; Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden., Lukaszuk T; Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland., Poleszczuk J; Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.

Journal Article , 2025

Vascular calcification inhibitors in chronic kidney disease.

Adoberg A; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia; Centre of Nephrology, North Estonia Medical Centre, Tallinn, Estonia. Electronic address: annika.adoberg@taltech.ee., Leis L; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia; Centre of Nephrology, North Estonia Medical Centre, Tallinn, Estonia., Luman M; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia; Centre of Nephrology, North Estonia Medical Centre, Tallinn, Estonia., Uhlin F; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia; Linköping University, Department of Health, Medicine and Caring Sciences, Linköping, Sweden., Fridolin I; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia., Viigimaa M; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia; Centre of Cardiology, North Estonia Medical Centre, Tallinn, Estonia., Holmar J; Tallinn University of Technology, Department of Health Technologies, Tallinn, Estonia.

Journal Article; Systematic Review , 2025

Loss of ADAMTS5 promotes vascular calcification via versican/integrin β1/FAK signal.

Zhu Z; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China; Department of Cardiology, Tongde Hospital of Zhejiang Province, PR China., Liu H; Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, PR China., Feng L; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China., Lu L; Department of Pathophysiolgy, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, 510080, PR China., Zhu J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China., Liang Q; Department of Anesthesiology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510665, PR China., Lan Z; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China., Ye Y; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China., Wang S; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China., Chen A; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China. Electronic address: chenan805@163.com., Yan J; Department of Cardiology, Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, 510280, PR China. Electronic address: yanjy790@smu.edu.cn.

Journal Article , 2025

Vitamin K preserves gamma-glutamyl carboxylase activity against carbamylations in uremia: Implications for vascular calcification and adjunct therapies.

Kaesler N; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany., Kaushik S; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany.; Biosciences, Cardiff University, Cardiff, UK., Frisch J; Institute of Biophysics, Center of Human and Molecular Biology (ZHMB), Center for Gender-Specific Biology and Medicine (CGBM), Saarland University, Homburg, Germany., Ziegler S; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany., Grommes J; Marienhospital Aachen, Clinic for Vascular Surgery, Aachen, Germany., Gombert A; Clinic for Vascular Surgery, University Hospital of the RWTH Aachen, Aachen, Germany., Roma LP; Institute of Biophysics, Center of Human and Molecular Biology (ZHMB), Center for Gender-Specific Biology and Medicine (CGBM), Saarland University, Homburg, Germany., Kuppe C; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany., Jankowski J; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital of the RWTH Aachen, Aachen, Germany.; Department of Pathology, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands.; Aachen-Maastricht Institute for CardioRenal Disease (AMICARE), University Hospital RWTH Aachen, Aachen, Germany., Floege J; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany., de la Puente-Secades S; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital of the RWTH Aachen, Aachen, Germany., Kramann R; Medical Clinic II, University Hospital of the RWTH Aachen, Aachen, Germany., Jankowski V; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital of the RWTH Aachen, Aachen, Germany.

Journal Article , 2025

Effect of osteoporosis medications on vascular and valvular calcification: a systematic review and meta-analysis.

Lo HZ; Peninsula Health, 2 Hastings Road, Frankston, VIC, 3199, Australia., Leow K; Department of Cardiology, Canberra Hospital, Woden, Yamba Dr, Garran, Australian Capital Territory, 2605, Australia., Hii R; Department of Medicine, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia., Nerlekar N; Department of Medicine, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia.; Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Monash Medical Centre, 246 Clayton Rd, Clayton, VIC, 3168, Australia.; Monash Cardiovascular Research Centre, Monash University and Monash Heart, Monash Health, 246 Clayton Rd, Clayton, VIC, 3168, Australia., Ebeling PR; Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Monash Medical Centre, 246 Clayton Rd, Clayton, VIC, 3168, Australia., Rodríguez AJ; Department of Medicine, School of Clinical Sciences at Monash Health, Bone and Muscle Health Research Group, Monash University, Monash Medical Centre Block E, Level 5, 246 Clayton Rd, Clayton, VIC, 3168, Australia. Alexander.Rodriguez@monash.edu.

Journal Article; Systematic Review; Meta-Analysis; Review , 2025

Thrombospondin-1 binds to integrin β3 to inhibit vascular calcification through suppression of NF-κB pathway.

Liu F; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Liang Q; Department of Anesthesiology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, PR China., Li L; Department of Cardiology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, PR China., Gong Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Li M; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, PR China., Feng L; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Chen A; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Ye Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Lan Z; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Li Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China., Ou JS; Division of Cardiac Surgery, National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, NHC Key Laboratory of Assisted Circulation, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China., Lu L; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, PR China., Yan J; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China.

Journal Article , 2025

Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor.

de la Puente-Secades S; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands., Mikolajetz D; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Gayrard N; Institut National de la Santé Et de la Recherche Médicale (INSERM), RD-Néphrologie and EA7288, Montpellier, France., Hermann J; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Jankowski V; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Bhargava S; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Meyer A; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Argilés À; Institut National de la Santé Et de la Recherche Médicale (INSERM), RD-Néphrologie and EA7288, Montpellier, France., Saritas T; Institute of Experimental Medicine and Systems Biology, Division of Nephrology, University Hospital RWTH Aachen, Aachen, Germany.; Division of Nephrology and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany., van der Vorst EPC; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany.; Interdisciplinary Centre for Clinical Research (IZKF), University Hospital RWTH Aachen, Aachen, Germany.; Aachen-Maastricht Institute for CardioRenal Disease (AMICARE), University Hospital RWTH Aachen, Aachen, Germany.; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, Munich, Germany., Wu Z; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Noels H; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany.; Aachen-Maastricht Institute for CardioRenal Disease (AMICARE), University Hospital RWTH Aachen, Aachen, Germany., Tepel M; Institute of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark., Alghamdi K; Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.; The University of Manchester, Faculty of Biology, Medicine and Health, Manchester, UK., Ward D; The University of Manchester, Faculty of Biology, Medicine and Health, Manchester, UK., Zidek W; Meoclinic, Department of Nephrology & Charité, Department of Nephrology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Wolf M; Department of Orthodontics, Dental Clinic, University Hospital RWTH Aachen, Aachen, Germany., Floege J; Division of Nephrology and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany., Schurgers L; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands.; Division of Nephrology and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany.; Aachen-Maastricht Institute for CardioRenal Disease (AMICARE), University Hospital RWTH Aachen, Aachen, Germany., Orth-Alampour S; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany., Jankowski J; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen 52074, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands.; Aachen-Maastricht Institute for CardioRenal Disease (AMICARE), University Hospital RWTH Aachen, Aachen, Germany.

Journal Article , 2025

Epigenetic Regulation of Human Vascular Calcification.

Kajuluri LP; Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA 02114, USA., Guo YY; Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA 02114, USA., Lee S; Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA 02114, USA., Christof M; School of Arts and Sciences, University of Rochester, Rochester, NY 14627, USA., Malhotra R; Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA 02114, USA.

Journal Article; Review , 2025

Calciprotein particle-activated endothelial cells aggravate smooth muscle cell calcification via paracrine signalling.

Feenstra L; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Zeper LW; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., van de Langenberg B; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., Kahlman EJEM; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., de La Roij G; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., Reijrink M; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Bernay B; Normandie Univ, UNICAEN, US EMerode, Plateform Proteogen, 14000, Caen, France., Chatre L; Université de Caen Normandie, CNRS, Normandie Université, ISTCT UMR6030, GIP CYCERON, 14000, Caen, France., Kuipers J; Department of Biomedical Sciences, University Medical Center of Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands., Giepmans BNG; Department of Biomedical Sciences, University Medical Center of Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands., Mastik MF; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Kooistra W; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Lodewijk ME; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Zuidscherwoude M; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., Pol RA; Department of Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Smith ER; Department of Nephrology, Royal Melbourne Hospital, Parkville, VIC, Australia.; Department of Medicine, University of Melbourne, Parkville, VIC, Australia.; SEHA Kidney Care, Abu Dhabi Health Services (SEHA), Abdu Dhabi, United Arab Emirates., Krenning G; Department of Clinical Pharmacy and Pharmacology, University Medical Center of Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., de Baaij JHF; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands., Hillebrands JL; Department of Pathology and Medical Biology (HPC: EA10), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. j.l.hillebrands@umcg.nl., Hoenderop JGJ; Department of Medical Biosciences, Radboud University Medical Center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands. joost.hoenderop@radboudumc.nl.

TransplantLines Investigators

Journal Article , 2025

Acetylation-ubiquitination crosstalk of DJ-1 mediates microcalcification formation in diabetic plaques via collagen-matrix vesicles interaction.

Sun Z; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.; Institute of Cardiovascular Diseases, Jiangsu University, Zhenjiang 212001, China., Li L; Department of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Wu Y; Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China., Zhang L; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Zang G; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Qian Y; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Yao H; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Mao X; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China., Wang Z; Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.; Institute of Cardiovascular Diseases, Jiangsu University, Zhenjiang 212001, China.

Journal Article , 2025

Involvement of miRNA-204 carried by the exosomes of macrophages in the AT2 receptor-mediated improvement of vascular calcification.

Bai HY; Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Lv XR; Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Gu HB; Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Li H; Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China. 9911263@163.com., Shan BS; Department of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China. shanbssuzhou@outlook.com.

Journal Article , 2025

STING Facilitates Vascular Calcification via p-STAT1/NLRP3 Signal.

Lu L; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China., Liu X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Gong Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Zhou X; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Chen A; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Li M; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China., Feng L; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Lan Z; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Ye Y; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China., Liang Q; Department of Anesthesiology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China., Yan J; Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, China.

Journal Article , 2025