Search Results - "and pathway"

Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies.

Yang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Zhang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Li Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Zhou X; Renal Path Diagnostics at Pathologists BioMedical Laboratories, Lewisville, TX, USA., Honda K; Department of Anatomy, Showa University School of Medicine, Tokyo, Japan., Kang D; Department of Anatomy, Showa University School of Medicine, Tokyo, Japan., Wang M; Boston University Medical Campus, Boston, USA., Yang JH; Clinical Systems Biology Laboratories, Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Xia Z; Clinical Systems Biology Laboratories, Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Wei Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Liu L; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Hu R; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China., Takaki T; Department of Anatomy, Showa University School of Medicine, Tokyo, Japan., Xing G; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China. xgl@zzu.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

DNA-damage orchestrates self-renewal and differentiation via reciprocal p53 family and Hippo/Wnt/TGF-β pathway activation in embryonic stem cells.

Ye Y; Department of Clinical Pathobiology and Immunological Testing, School of Medical Laboratory, Qilu Medical University, Zibo, 255300, China., Xie W; Cam-Su Genomic Resource Center, Medical College of Soochow University, Suzhou, China., Wang X; Cam-Su Genomic Resource Center, Medical College of Soochow University, Suzhou, China., Tan S; Cam-Su Genomic Resource Center, Medical College of Soochow University, Suzhou, China., Yang L; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200120, China.; Guangzhou National Laboratory, Guangzhou International Bio Island, Guangzhou, 510005, Guangdong, China., Ma Z; Cam-Su Genomic Resource Center, Medical College of Soochow University, Suzhou, China., Zhu Z; Institute of Health and Medicine, Hefei Comprehensive National Science Center, 4090 Guanhai Road, Heifei, China., Chen X; Department of Biology, Southern University of Science and Technology, Shenzhen, China., Liu X; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200120, China., O'Neill E; Department of Oncology, University of Oxford, Oxford, UK. eric.oneill@oncology.ox.ac.uk., Chang L; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Jiangsu Province International Joint Laboratory for Regeneration Medicine, Medical College of Soochow University, Suzhou, China. changlei@suda.edu.cn., Zhang W; Cam-Su Genomic Resource Center, Medical College of Soochow University, Suzhou, China. zhangwensheng@suda.edu.cn.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Gannan Innovation and Translational Medicine Research Institute, Gannan Medical University, Ganzhou, China. zhangwensheng@suda.edu.cn.

Journal Article , 2025

Biliary atresia: insights into mechanisms using a toxic model of the disease including Wnt and Hippo signaling pathways and microtubules.

Fried S; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Har-Zahav A; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Hamudi Y; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Mahameed S; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Mansur R; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Dotan M; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Cozacov T; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Shamir R; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel., Wells RG; Division of Gastroenterology and Hepatology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Waisbourd-Zinman O; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel. orithw@tauex.tau.ac.il.; Faculty of Medicine and Health Sciences, Felsenstein Medical Research Center, Tel-Aviv University, Tel-Aviv, Israel. orithw@tauex.tau.ac.il.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. orithw@tauex.tau.ac.il.

Journal Article , 2025

C1q/MASP Complexes-Hybrid Complexes of Classical and Lectin Pathway Proteins Are Found in the Circulation.

Rosbjerg A; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Plchová TA; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Bayarri-Olmos R; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Holm BE; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Pedersen IS; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Skjoedt MO; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Garred P; Department of Clinical Immunology, Laboratory of Molecular Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Journal Article , 2024

MST1 selective inhibitor Xmu-mp-1 ameliorates neuropathological changes in a rat model of sporadic Alzheimer's Disease by modulating Hippo-Wnt signaling crosstalk.

Sahu MR; Laboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India., Ahmad MH; Laboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India., Mondal AC; Laboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India. acmondal@mail.jnu.ac.in.

Journal Article , 2024

Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis.

Chen W; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States.; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States., Lu Y; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States., Zhang Y; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States., Wu J; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States., McVicar A; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., Chen Y; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., Zhu S; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., Zhu G; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States., Lu Y; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., Zhang J; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., McConnell M; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States., Li YP; Division in Cellular and Molecular Medicine, Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, Tulane University, New Orleans, United States.; Department of Pathology, School of Medicine, University of Alabama at Birmingham, Birmingham, United States.

Journal Article , 2024

Gingival Stem Cell-Conditioned Media and Low-Level Laser Therapy Enhance Periodontal Ligament Stem Cells Function by Upregulating Wnt and TGF-β Pathway Components: An In Vitro Study.

Aljabri MY; Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia., Alhazmi YA; Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia., Elsayyad SA; Dental Science Research Group, Health Research Centre of Excellence, The British University in Egypt (BUE), El Sherouk City, Egypt., Saber SM; Dental Science Research Group, Health Research Centre of Excellence, The British University in Egypt (BUE), El Sherouk City, Egypt.; Department of Endodontics, Faculty of Dentistry, The British University in Egypt (BUE), El Sherouk City, Egypt.; Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt., Shamel M; Dental Science Research Group, Health Research Centre of Excellence, The British University in Egypt (BUE), El Sherouk City, Egypt.; Oral Biology Department, Faculty of Dentistry, The British University in Egypt, Cairo, Egypt.

Journal Article , 2025

Therapeutic targets in the Wnt signaling pathway: Treating cancer with specificity.

Zhang J; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China., Guo H; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China., Gong C; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China., Shen J; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China., Jiang G; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China., Liu J; State Key Laboratory of Flexible Electronics (LoFE), Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China., Liang T; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China. Electronic address: tmliang@njnu.edu.cn., Guo L; State Key Laboratory of Flexible Electronics (LoFE), Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China. Electronic address: lguo@njupt.edu.cn.

Journal Article; Review; Research Support, Non-U.S. Gov't , 2025

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.

Hao Y; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhang X; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Ran S; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Li Y; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Ye W; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Wang S; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Li X; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Luo Z; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhao J; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zong J; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zheng K; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Li R; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhang H; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Lai L; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Huang P; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zou Z; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhan W; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Yue Z; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Wu J; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Xia J; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Journal Article , 2025

The function of circular RNAs in regulating Wnt/β-catenin signaling: An innovative therapeutic strategy for breast and gynecological cancers.

Kahkesh S; Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran., Hedayati N; School of Medicine, Iran University of Medical Science, Tehran, Iran., Rahimzadeh P; Surgical Research Society (SRS), Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran., Farahani N; Farhikhtegan Medical Convergence Sciences Research Center, Farhikhtegan Hospital Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Khoozani MF; Department of Cell and Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran., Abedi M; Department of Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran., Nabavi N; Independent Researcher, Victoria, British Columbia, Canada., Naeimi B; Academic Center for Education, Culture and Research (ACECR)-Khorasan Razavi, Mashhad, Iran., Khoshnazar SM; Gastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran. Electronic address: m.khoshnazar@kmu.ac.ir., Alimohammadi M; Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: mina.alimohammadi@sbmu.ac.ir., Alaei E; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: e.alaei2000@gmail.com., Mahmoodieh B; Young Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Electronic address: behi_mahmodieh@yahoo.com.

Journal Article; Review , 2025

PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight.

Ozel B; Ege University, Faculty of Medicine, Medical Biology Department, Izmir, Turkey., Kipcak S; Ege University, Faculty of Medicine, Medical Biology Department, Izmir, Turkey., Caglar HO; Department of Molecular Biology and Genetics, Science Faculty, Erzurum Technical University, Erzurum, Turkey., Kayabasi C; Balıkesir University, Faculty of Medicine, Medical Biology Department, Balıkesir, Turkey., Goker Bagca B; Aydın Adnan Menderes University, Faculty of Medicine, Medical Biology Department, Aydın, Turkey., Gunduz C; Ege University, Faculty of Medicine, Medical Biology Department, Izmir, Turkey., Selvi Gunel N; Ege University, Faculty of Medicine, Medical Biology Department, Izmir, Turkey., Biray Avci C; Ege University, Faculty of Medicine, Medical Biology Department, Izmir, Turkey. cigir.biray@ege.edu.tr.

Journal Article , 2025

IDO1-mediated AhR activation up-regulates pentose phosphate pathway via NRF2 to inhibit ferroptosis in lung cancer.

Zhan J; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Chen Y; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Liu Y; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Chen Y; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Li Z; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Li X; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., He Z; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Meng F; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Qian X; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China., Yang L; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China. Electronic address: yanglili@tjmuch.com., Yang Q; State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, Fudan University, Shanghai, China. Electronic address: yangqing68@fudan.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Natural small molecule thymoquinone increases the chemosensitivity of glioblastoma to temozolomide through inhibiting Wnt/β-catenin signaling pathway to downregulate MGMT expression: In vitro and in vivo validation.

Bai P; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Wang P; Department of Neurosurgery, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China., Ren T; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Tang Q; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Lin Z; OmixScience Research Institute, OmixScience Co., Ltd., Hangzhou 311199, China; Liangzhu Laboratory, Zhejiang University, Hangzhou 311100, China., Zhang N; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Zhao L; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Zhong R; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Sun G; Beijing Key Laboratory of Environmental and Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China. Electronic address: sunguohui@bjut.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Genetic insight into lung neuroendocrine tumors: Notch and Wnt signaling pathways as potential targets.

Pecora G; Unit of Endocrinology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, AOU Sant'Andrea, ENETS Center of Excellence, Rome, Italy.; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Mancini C; Unit of Endocrinology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, AOU Sant'Andrea, ENETS Center of Excellence, Rome, Italy.; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Mazzilli R; Unit of Endocrinology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, AOU Sant'Andrea, ENETS Center of Excellence, Rome, Italy., Zamponi V; Unit of Endocrinology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, AOU Sant'Andrea, ENETS Center of Excellence, Rome, Italy.; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Telese S; Department of Clinical and Molecular Medicine, Sant'Andrea Hospital-Sapienza University of Rome, Rome, Italy., Scalera S; Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Maugeri-Saccà M; Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Ciuffreda L; UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy., De Nicola F; UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy., Fanciulli M; UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy., La Salvia A; National Center for Drug Research and Evaluation, National Institute of Health (ISS), Rome, Italy., Mancini M; Morphologic and Molecular Pathology Unit, S. Andrea University Hospital, Rome, Italy., Vecchione A; Department of Clinical and Molecular Medicine, Sant'Andrea Hospital-Sapienza University of Rome, Rome, Italy.; Morphologic and Molecular Pathology Unit, S. Andrea University Hospital, Rome, Italy., Siciliani A; Department of Thoracic Surgery, Sant'Andrea University Hospital, Rome, Italy., Ibrahim M; Department of Thoracic Surgery, Sant'Andrea University Hospital, Rome, Italy., Bellavia D; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Isidori AM; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Faggiano A; Unit of Endocrinology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, AOU Sant'Andrea, ENETS Center of Excellence, Rome, Italy. antongiulio.faggiano@uniroma1.it., Mancini R; Department of Clinical and Molecular Medicine, Sant'Andrea Hospital-Sapienza University of Rome, Rome, Italy.; Morphologic and Molecular Pathology Unit, S. Andrea University Hospital, Rome, Italy., De Vitis C; Department of Clinical and Molecular Medicine, Sant'Andrea Hospital-Sapienza University of Rome, Rome, Italy.

Journal Article , 2025

Ginseng extract and total ginsenosides protect the function of hematopoietic stem cells by activating the Notch and Wnt signal pathways.

Gao X; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: 1459257481@qq.com., Qian B; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; Thoracic Surgery Department, The First Hospital of Jilin University, Changchun, Jilin, 130021, China. Electronic address: qianbx@jlu.edu.cn., Yuan T; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: 2755576457@qq.com., Pan D; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; Thoracic Surgery Department, The First Hospital of Jilin University, Changchun, Jilin, 130021, China. Electronic address: 18744030771@163.com., Liang Z; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: Liangzg123@126.com., Yin Y; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: yinyifei000121@163.com., Liu S; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: 18443402046@163.com., Li X; Northeast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: xiangyan_li1981@163.com., Zhao D; Northeast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: zhaodaqing1963@163.com., Zhang H; Research Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130021, China; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130117, China. Electronic address: 13843148162@163.com.

Journal Article , 2025

ANG-Modified Liposomes Coloaded With α-Melittin and Resveratrol Induce Apoptosis and Pyroptosis in Glioblastoma Cells by Impeding Wnt/β-Catenin Signaling.

Zhang HQ; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Wang Y; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Geng X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Dong M; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Liu Z; The Second Hospital of Jilin University, Changchun, China., Sun C; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Yu K; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China., Xin W; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing, China., Xu Y; Basic College of Medicine, Jilin Medical University, Jilin, China., Xu N; Basic College of Medicine, Jilin Medical University, Jilin, China., Liu W; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Science, Changchun, China.

Journal Article , 2025

The differentiation of glial precursors into neuronal-like cells through the Wnt and Neurotrophin signaling pathways via Ctnnβ1.

Ma W; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, China., Yang JW; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, China.; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Zhang T; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Weng XH; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, China., Shen L; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, China., Zhao SH; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., He Y; Gastroenterology Department, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Wu ZZ; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Li FF; Gastroenterology Department, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Shang Y; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Guo JH; Second Department of General Surgery, First People's Hospital of Yunnan Province, Kunming, Yunnan, China., Li LY; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, China.

Journal Article , 2025

The pentose phosphate pathway (PPP) in the glioma metabolism: A potent enhancer of malignancy.

Trejo-Solís C; Laboratorio Experimental de Enfermedades Neurodegenerativas, Unidad Periférica para el Estudio de la Neuroinflamación, Laboratorio de Neuropatologia Experimental, Instituto Nacional de Neurología y Neurocirugía, CDMX, 14269, Mexico. Electronic address: cristina.trejo@innn.edu.mx., Escamilla-Ramírez Á; Service de Neuro-Oncologie, Hospitaux Universitaires Pitie Salpetriere, Paris, France. Electronic address: aucasaga@yahoo.com.mx., Gómez-Manzo S; Laboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, CDMX, 04530, Mexico. Electronic address: saulmanzo@ciencias.unam.mx., Castillo-Rodriguez RA; CICATA Unidad Morelos, Instituto Politécnico Nacional, Boulevard de la Tecnología, 1036 Z-1, P 2/2, Atlacholoaya, 62790, Xochitepec, Mexico. Electronic address: racastillo@ipn.mx., Palomares-Alonso F; Laboratorio Experimental de Enfermedades Neurodegenerativas, Unidad Periférica para el Estudio de la Neuroinflamación, Laboratorio de Neuropatologia Experimental, Instituto Nacional de Neurología y Neurocirugía, CDMX, 14269, Mexico., Castillo-Pérez C; Laboratorio Experimental de Enfermedades Neurodegenerativas, Unidad Periférica para el Estudio de la Neuroinflamación, Laboratorio de Neuropatologia Experimental, Instituto Nacional de Neurología y Neurocirugía, CDMX, 14269, Mexico. Electronic address: ccastillo@innn.edu.mx., Jiménez-Farfán D; Laboratorio de Inmunología, División de Estudios de Posgrado e Investigación, Facultad de Odontología, Universidad Nacional Autónoma de México, 04510, Ciudad de Mexico, Mexico. Electronic address: farfanmd@unam.mx., Sánchez-García A; Laboratorio Experimental de Enfermedades Neurodegenerativas, Unidad Periférica para el Estudio de la Neuroinflamación, Laboratorio de Neuropatologia Experimental, Instituto Nacional de Neurología y Neurocirugía, CDMX, 14269, Mexico., Gallardo-Pérez JC; Departamento de Fisiopatología Cardio-Renal, Instituto Nacional de Cardiología, 14080, Ciudad de Mexico, Mexico; Facultad de Ciencias, Universidad Nacional Autónoma de México, 04510, Ciudad de México, Mexico. Electronic address: jcgallardo@ciencias.unam.mx.

Journal Article; Review , 2025

Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis.

Laffer B; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany., Ohms M; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany., Kenno S; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany., Tsui P; Kira Pharmaceuticals, Research and Development, Cambridge, MA, United States., Ehlers-Jeske E; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany., Song W; Kira Pharmaceuticals, Research and Development, Cambridge, MA, United States., Song WC; Department of Systems Pharmacology and Translational Therapeutics, The University of Pennsylvania, Philadelphia, PA, United States., Köhl J; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany.

Journal Article , 2025

Cell type-specific regulation of the pentose phosphate pathway during development and metabolic stress-driven autoimmune diseases: Relevance for inflammatory liver, renal, endocrine, cardiovascular and neurobehavioral comorbidities, carcinogenesis, and aging.

Banki K; Departments of Medicine, Microbiology and Immunology, Biochemistry and Molecular Biology, and Pathology, State University of New York Upstate Medical University, Norton College of Medicine, 750 East Adams Street, Syracuse, NY 13210, USA., Perl A; Departments of Medicine, Microbiology and Immunology, Biochemistry and Molecular Biology, and Pathology, State University of New York Upstate Medical University, Norton College of Medicine, 750 East Adams Street, Syracuse, NY 13210, USA. Electronic address: perla@upstate.edu.

Journal Article; Review , 2025