Sökresultat - "beta-catenin"

A Longitudinal Study of E-Cadherin and Beta-Catenin in Progression of Oral Epithelial Dysplasia.

Yim IS; Faculty of Dentistry, The University of British Columbia, Vancouver, British Columbia, Canada.; BC Oral Cancer Prevention Program, Cancer Control Research, BC Cancer Research Institute, Vancouver, British Columbia, Canada., Zhang L; Faculty of Dentistry, The University of British Columbia, Vancouver, British Columbia, Canada.; BC Oral Cancer Prevention Program, Cancer Control Research, BC Cancer Research Institute, Vancouver, British Columbia, Canada., Rock LD; Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.; Beatrice Hunter Cancer Research Institute, Halifax, Nova Scotia, Canada., Rosin MP; BC Oral Cancer Prevention Program, Cancer Control Research, BC Cancer Research Institute, Vancouver, British Columbia, Canada.; Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada., Lin I; Faculty of Dentistry, The University of British Columbia, Vancouver, British Columbia, Canada.; BC Oral Cancer Prevention Program, Cancer Control Research, BC Cancer Research Institute, Vancouver, British Columbia, Canada., Laronde DM; Faculty of Dentistry, The University of British Columbia, Vancouver, British Columbia, Canada.; BC Oral Cancer Prevention Program, Cancer Control Research, BC Cancer Research Institute, Vancouver, British Columbia, Canada.

Journal Article , 2025

Structure-activity relationship explorations of 2-(isoxazol-5-yl)phenyl-3,4-dihydroxybenzoate derivatives to develop potent Wnt/β-catenin pathway inhibitors for colorectal cancer treatment.

Dong L; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China. Electronic address: dongli@gmc.edu.cn., Long T; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China., Zhang S; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China., Mao Y; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China., Liu M; Pharmacy Department, Guizhou Provincial People's Hospital, Nanming District, 550002, Guiyang, China., Zhao F; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China., Yang Z; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China., Li L; Guizhou Provincial Center for Disease Control and Prevention, Guiyang 550004, China., Chen SW; School of Pharmacy, Lanzhou University, Lanzhou 730000, China. Electronic address: chenshw@lzu.edu.cn., Liao S; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China. Electronic address: sgliao@gmc.edu.cn., Dong Y; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province & School of Pharmacy, Guizhou Medical University, Guian New District, 561113, China. Electronic address: dongyongxi@gmc.edu.cn.

Journal Article , 2025

Bisphenols exposure at environmentally relevant dose promoted ovarian cancer progression and modulated tumor microenvironment through β-catenin/SPP1 axis.

Xu S; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China., Yuan X; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China., Wang Y; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China., Fu Z; Department of Gynecology and Obstetrics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Chen K; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China; Department of Gynecology and Obstetrics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Cui Z; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China., Xu L; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China., Zhang H; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Xia D; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address: dxia@zju.edu.cn., Wu Y; Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address: georgewu@zju.edu.cn.

Journal Article , 2025

The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling.

Kassel S; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Yuan K; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Bunnag N; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Department of Biochemistry and Cell Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Neitzel LR; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Lu W; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Schwarzkopf A; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Maines B; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Loberg MA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Xu G; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Adams A; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., McCray AD; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Cho A; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Rockouski M; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Orton G; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Goldsmith L; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Aronno MMA; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Spencer ZT; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Khan OM; Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Ye F; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Williams C; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Lebensohn AM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Rohatgi R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Wang X; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA., Weiss VL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Hong CC; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Kettenbach AN; Department of Biochemistry and Cell Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA., Robbins DJ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Ahmed Y; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA. yashi.ahmed@dartmouth.edu.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA. yashi.ahmed@dartmouth.edu., Lee E; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA. ethan.lee@vanderbilt.edu.; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA. ethan.lee@vanderbilt.edu.

Journal Article , 2025

Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185.

Yang YJ; Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, #138 Sheng Li Road, Tainan, 70428, Taiwan. yaojong@mail.ncku.edu.tw.; Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. yaojong@mail.ncku.edu.tw., Wu CT; Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Cheng HC; Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chen WY; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Tseng JT; College of Life Science and Medicine, National Tsing Hua University, Hsinchu, Taiwan., Chang WL; Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Sheu BS; Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. sheubs@mail.ncku.edu.tw.; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. sheubs@mail.ncku.edu.tw.

Journal Article; Review , 2025

IRX2 and NPTX1 differential regulation of β-catenin underlies MEK-mediated proliferation in human neuroglial cells.

Chen A; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Wang H; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Li X; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Anastasaki C; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Gutmann DH; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA gutmannd@wustl.edu.

Journal Article , 2025

Rictor orchestrates β-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer.

Zhao X; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Lai H; Department of Gynecology, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China., Li G; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Qin Y; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Chen R; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Labrie M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Stommel JM; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Mills GB; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA., Ma D; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. dma@tjh.tjmu.edu.cn.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. dma@tjh.tjmu.edu.cn., Gao Q; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. qlgao@tjh.tjmu.edu.cn.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. qlgao@tjh.tjmu.edu.cn., Fang Y; National Clinical Research Center for Obstetrics and Gynaecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. tongjify@163.com.; Department of Gynaecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. tongjify@163.com.

Journal Article , 2025

Beta-catenin/sirtuin 1/farnesoid X receptor pathway promotion of portal vein ligation and parenchymal transection-induced rapid liver regeneration.

Tong Y; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Provincial Key Laboratory of Precise Diagnosis and Treatment of Abdominal Infection, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Gu Q; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Department of Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Dong B; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Provincial Key Laboratory of Precise Diagnosis and Treatment of Abdominal Infection, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Ying H; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Ji T; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Shen X; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Shen B; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Provincial Key Laboratory of Precise Diagnosis and Treatment of Abdominal Infection, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Yu H; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Provincial Key Laboratory of Precise Diagnosis and Treatment of Abdominal Infection, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Feng L; Department of Biomedical Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Cai X; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Li Z; Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Liver Regeneration and Metabolism Study Group, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Department of General Surgery, Alaer Hospital, School of Medicine, Tarim University, Alar, Xinjiang, China. Electronic address: 3313007@zju.edu.cn.

Journal Article , 2025

The function of β-catenin and GSK-3β in Procambarus clarkii Wnt signaling pathway during Spiroplasma eriocheiris infection.

Bi K; Animal Husbandry and Veterinary College, Jiangsu Vocational College of Agriculture and Forestry, Jurong, Jiangsu 212400, China., Li J; Key Laboratory of Genetic Breeding and cultivation for Freshwater Crustacean, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, China., Yang J; Jiangsu Key Laboratory for Aquatic Crustacean Diseases, College of Marine Science and Engineering, Nanjing Normal University, 2 Xuelin Road, Nanjing, 210023, China., Qiu S; Jiangsu Key Laboratory for Aquatic Crustacean Diseases, College of Marine Science and Engineering, Nanjing Normal University, 2 Xuelin Road, Nanjing, 210023, China., Zhang K; Animal Husbandry and Veterinary College, Jiangsu Vocational College of Agriculture and Forestry, Jurong, Jiangsu 212400, China., Wang H; Animal Husbandry and Veterinary College, Jiangsu Vocational College of Agriculture and Forestry, Jurong, Jiangsu 212400, China., Hu K; Animal Husbandry and Veterinary College, Jiangsu Vocational College of Agriculture and Forestry, Jurong, Jiangsu 212400, China., Chen L; Animal Husbandry and Veterinary College, Jiangsu Vocational College of Agriculture and Forestry, Jurong, Jiangsu 212400, China., Xu Y; Key Laboratory of Genetic Breeding and cultivation for Freshwater Crustacean, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, China. Electronic address: jsgyxuyu@126.com., Meng Q; Jiangsu Key Laboratory for Aquatic Crustacean Diseases, College of Marine Science and Engineering, Nanjing Normal University, 2 Xuelin Road, Nanjing, 210023, China. Electronic address: mlzzcld@aliyun.com.

Journal Article , 2025

Activated Notch1 promotes macrophage polarization and exacerbates sepsis-induced acute lung injury via β-catenin/NF-κB signaling.

Liu Z; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Lei Y; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Zuo J; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Zhang R; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Du H; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Hu H; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Zheng J; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China., Yang P; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China; Children's Digital Health and Data Center of Wuhan University, Wuhan 430071, China. Electronic address: yangpu@whu.edu.cn., Zhao D; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China; Children's Digital Health and Data Center of Wuhan University, Wuhan 430071, China. Electronic address: dczhao@whu.edu.cn.

Journal Article , 2025

IGF1R activates FOXP3-β-catenin signaling to promote breast cancer development.

Li L; Radiation Oncology Key Laboratory of Sichuan Province, Department of Radiotherapy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, 610041, China., Zhang Z; Key Laboratory of Environmental and Applied Microbiology, Key Laboratory of Environmental Microbiology of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China., Huang N; Radiation Oncology Key Laboratory of Sichuan Province, Department of Radiotherapy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, 610041, China., Ren J; Radiation Oncology Key Laboratory of Sichuan Province, Department of Radiotherapy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, 610041, China., Qin Y; Radiation Oncology Key Laboratory of Sichuan Province, Department of Radiotherapy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, 610041, China. qinyuan@scszlyy.org.cn., Luo Y; Radiation Oncology Key Laboratory of Sichuan Province, Department of Radiotherapy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, 610041, China. luoyk@sichuancancer.org.

Journal Article , 2025

A potential therapeutic molecule target: lncRNA AK023507 inhibits the metastasis of breast cancer by regulating the WNT/DOCK4/β-catenin axis.

Diao B; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 96, Fuxue Lane, Lucheng District, Wenzhou, 325000, China., Cai Y; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 96, Fuxue Lane, Lucheng District, Wenzhou, 325000, China.; Department of Thyroid and Breast Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, 318000, China., Song D; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 96, Fuxue Lane, Lucheng District, Wenzhou, 325000, China., Hu Y; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 96, Fuxue Lane, Lucheng District, Wenzhou, 325000, China., Xie B; Department of Thyroid and Breast Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, 318000, China., Kan Y; Department of Thyroid and Breast Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, 318000, China., Hu X; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 96, Fuxue Lane, Lucheng District, Wenzhou, 325000, China. drhxj@126.com.

Journal Article , 2025

ARHGAP17 Inhibits Hepatocellular Carcinoma Progression by Inactivation of Wnt/β-Catenin Signaling Pathway.

Fan S; Graduate Training Base, General Hospital of Northern Theater Command of Jinzhou Medical University, Shenyang, 110016, Liaoning, China.; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Zhao H; Graduate School, Jinzhou Medical University, Jinzhou, 121000, Liaoning, China., Li C; Department of Immunology, The College of Basic Medical Sciences, China Medical University, Shenyang, 110122, Liaoning, China., Chen X; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Sun M; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Chen F; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Long C; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Zhou Y; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Nan B; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Zhao H; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China., Zhang W; Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang, 110016, Liaoning, China. zhang_wei_1980@163.com.

Journal Article , 2025

YAP/TAZ, beta-catenin, and TGFb pathway activation in medical plasma-induced wound healing in diabetic mice.

Schmidt A; ZIK plasmatis, Leibniz-Institute for Plasma Science and Technology (INP), a member of the Leibniz Health Technologies Research Alliance, Felix-Hausdorff-Str. 2, 17489 Greifswald, Germany. Electronic address: anke.schmidt@inp-greifswald.de., von Woedtke T; ZIK plasmatis, Leibniz-Institute for Plasma Science and Technology (INP), a member of the Leibniz Health Technologies Research Alliance, Felix-Hausdorff-Str. 2, 17489 Greifswald, Germany; Institute for Hygiene and Environmental Medicine, Greifswald University Medical Center, Sauerbruchstr., 17475 Greifswald, Germany., Weltmann KD; ZIK plasmatis, Leibniz-Institute for Plasma Science and Technology (INP), a member of the Leibniz Health Technologies Research Alliance, Felix-Hausdorff-Str. 2, 17489 Greifswald, Germany., Bekeschus S; ZIK plasmatis, Leibniz-Institute for Plasma Science and Technology (INP), a member of the Leibniz Health Technologies Research Alliance, Felix-Hausdorff-Str. 2, 17489 Greifswald, Germany; Department of Clinic and Policlinic for Dermatology and Venerology, Rostock University Medical Center, Strempelstr. 13, 18057 Rostock, Germany. Electronic address: sander.bekeschus@inp-greifswald.de.

Journal Article , 2025

Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers.

Lehrich BM; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, PA, USA., Delgado ER; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Pathology, Division of Experimental Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Yasaka TM; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, PA, USA., Liu S; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Cao C; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Liu Y; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Taheri MN; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Pathology, Division of Experimental Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA., Guan X; Translational Medicine, Genentech Inc., San Francisco, CA, USA., Koeppen H; Translational Medicine, Genentech Inc., San Francisco, CA, USA., Singh S; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Meadows V; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Liu JJ; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Singh-Varma A; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Krutsenko Y; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Poddar M; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Hitchens TK; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Foley LM; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Liang B; Hepatic Surgery Center, Department of Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Rialdi A; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rai RP; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Patel P; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Riley M; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bell A; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Raeman R; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Dadali T; Alnylam Pharmaceuticals, Boston, MA, USA., Luke JJ; UPMC Hillman Cancer Center and University of Pittsburgh, Pittsburgh, PA, USA., Guccione E; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ebrahimkhani MR; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Pathology, Division of Experimental Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA., Lujambio A; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen X; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Maier M; Alnylam Pharmaceuticals, Boston, MA, USA., Wang Y; Translational Medicine, Genentech Inc., San Francisco, CA, USA., Broom W; Alnylam Pharmaceuticals, Boston, MA, USA., Tao J; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. junyantao2010@gmail.com.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. junyantao2010@gmail.com.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA. junyantao2010@gmail.com., Monga SP; Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. smonga@pitt.edu.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. smonga@pitt.edu.; Pittsburgh Liver Research Center, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA. smonga@pitt.edu.; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. smonga@pitt.edu.

Journal Article , 2025

Wnt/β-catenin regulates Gli1 + osteogenic progenitors in condylar subchondral bone development and osteoarthritis.

Wang J; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, P. R. China., Sun L; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, P. R. China., Zhang Y; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, P. R. China., Chen S; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, P. R. China. chens@bjmu.edu.cn., He Y; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, P. R. China. fridaydust1983@163.com.

Journal Article , 2025

Effects of Adolescent Social Isolation on PFC's β-Catenin Levels and Anxiety-Like Behaviors in Male and Female Rats: Study of the Role of Dopaminergic D2 Receptors.

Funes A; Laboratorio de Toxicología Experimental, Departamento de Ciencias de los Alimentos y del Medioambiente, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, S2002LRL, Argentina., Ramirez AI; Laboratorio de Toxicología Experimental, Departamento de Ciencias de los Alimentos y del Medioambiente, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, S2002LRL, Argentina.; CONICET-Rosario, S2000EZP, Rosario, Santa Fe, Argentina., Konjuh CN; Laboratorio de Toxicología Experimental, Departamento de Ciencias de los Alimentos y del Medioambiente, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, S2002LRL, Argentina., Rosso SB; Laboratorio de Toxicología Experimental, Departamento de Ciencias de los Alimentos y del Medioambiente, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, S2002LRL, Argentina.; CONICET-Rosario, S2000EZP, Rosario, Santa Fe, Argentina., Cuesta S; Department of Cell Biology and Neurosciences, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854 - 8000, USA., Pacchioni AM; Laboratorio de Toxicología Experimental, Departamento de Ciencias de los Alimentos y del Medioambiente, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, S2002LRL, Argentina. pacchioni.alejandra@conicet.gov.ar.; CONICET-Rosario, S2000EZP, Rosario, Santa Fe, Argentina. pacchioni.alejandra@conicet.gov.ar.

Journal Article , 2025

CDX1 and CDX2 suppress colon cancer stemness by inhibiting β-catenin-facilitated formation of Pol II-DSIF-PAF1C complex.

Aoki K; Department of Pharmacology, Faculty of Medicine, University of Fukui, Fukui, Japan. aokik@u-fukui.ac.jp.; Life Science Support Center, University of Fukui, Fukui, Japan. aokik@u-fukui.ac.jp., Nitta A; Department of Pharmacology, Faculty of Medicine, University of Fukui, Fukui, Japan., Igarashi A; Department of Pharmacology, Faculty of Medicine, University of Fukui, Fukui, Japan.

Journal Article , 2025

Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma.

Wong K; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Bishop JA; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Weinreb I; Laboratory Medicine Program, University Health Network, Toronto General Hospital, Toronto, ON, Canada.; Department of Pathobiology and Laboratory Medicine, University of Toronto, Toronto, ON, Canada., Motta M; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Del Castillo Velasco-Herrera M; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Bellacchio E; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Ferreira I; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., van der Weyden L; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Boccacino JM; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Lauri A; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Rotundo G; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Ciolfi A; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Cheema S; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Olvera-León R; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Offord V; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Droop A; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Vermes I; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Allgäuer M; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Hyrcza M; Department of Pathology and Laboratory Medicine, University of Calgary, Arnie Charboneau Cancer Institute, Calgary, AB, Canada., Anderson E; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., Smith K; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK., de Saint Aubain N; Department of Pathology, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles, Brussels, Belgium., Mogler C; School of Medicine and Health, Technical University Munich, Munich, Germany., Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Arends MJ; Edinburgh Pathology, Cancer Research UK Scotland Centre, The University of Edinburgh, Institute of Genetics and Cancer, Edinburgh, UK., Brenn T; Departments of Pathology and Dermatology, University of Michigan, Ann Arbor, Michigan, USA., Tartaglia M; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy., Adams DJ; Experimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK. da1@sanger.ac.uk.

Journal Article , 2025

The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes.

Jauregi-Miguel A; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Söderholm S; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Science for Life Laboratory, SciLifeLab, Linköping University, Linköping 58183, Sweden., Weiss T; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Science for Life Laboratory, SciLifeLab, Linköping University, Linköping 58183, Sweden., Nordin A; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Science for Life Laboratory, SciLifeLab, Linköping University, Linköping 58183, Sweden., Ghezzi V; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Brütsch SM; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Pagella P; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Department of Physics, Chemistry, and Biology, Division of Biophysics and Bioengineering, Faculty of Science and Engineering, Linköping University, Linköping 58183, Sweden., van de Grift Y; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Science for Life Laboratory, SciLifeLab, Linköping University, Linköping 58183, Sweden., Zambanini G; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Ulisse J; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Mattia A; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Deviatiiarov R; Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan 420012, Russian Federation.; Endocrinology Research Center, Moscow 115478, Russian Federation.; Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan., Faustini E; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Moparthi L; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Zhong W; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Björnsson B; Department of Surgery in Linköping, Linköping University, Linköping 58225, Sweden.; Department of Biomedicine and Clinical Sciences, Linköping University, Linköping 58225, Sweden., Sandström P; Department of Surgery in Linköping, Linköping University, Linköping 58225, Sweden.; Department of Biomedicine and Clinical Sciences, Linköping University, Linköping 58225, Sweden., Lundqvist E; Department of Biomedicine and Clinical Sciences, Linköping University, Linköping 58225, Sweden.; Department of Surgery, Vrinnevi Hospital, Norrköping, Linköping University, Norrköping 60379, Sweden., Lottersberger F; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Koch S; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., Moor AE; Department of Biosystems Science and Engineering, Federal Institute of Technology Zürich, Basel 4056, Switzerland., Sun XF; Department of Oncology, Division of Surgery, Orthopedics and Oncology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Department of Biomedical and Clinical Sciences, Division of Surgery, Orthopedics and Oncology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden., von Castelmur E; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Physics, Chemistry and Biology, Division of Chemistry, Faculty of Science and Engineering, Linköping University, Linköping 58183, Sweden., Sheng G; International Research Center for Medical Sciences, Kumamoto University, Kumamoto 860-8555, Japan., Cantù C; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping 58183, Sweden.; Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58225, Sweden.; Science for Life Laboratory, SciLifeLab, Linköping University, Linköping 58183, Sweden.

Journal Article , 2025