Search Results - "farnesoid X receptor"

Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction.

Qian, Shuwen^1,2,3 (AUTHOR) shuwen_qian@tongji.edu.cn, Su, Zehua^2,3 (AUTHOR), Lin, Jiaqi^2,3 (AUTHOR), Hou, Qianhao^2,3 (AUTHOR), Wang, Xiaomei² (AUTHOR), Li, Yuling⁴ (AUTHOR), Wang, Jieying⁵ (AUTHOR), Huang, Changchun⁶ (AUTHOR), Wang, Zetian^2,3 (AUTHOR), Cubero, Francisco Javier⁷ (AUTHOR), Wang, Xiangrui^2,3 (AUTHOR) xiangruiwang@vip.sina.com, Liao, Lijun^2,3 (AUTHOR) liao@pan-intelligence.com

Human umbilical cord mesenchymal stem cell-derived exosomes repair IBD by activating the SIRT1-FXR pathway in macrophages.

Zhou, Mengjiao^1,2 (AUTHOR) 1805711101@qq.com, Pei, Bing³ (AUTHOR) shxpeibing@outlook.com, Cai, Peipei¹ (AUTHOR) caipei1314@163.com, Yi, Chengxue⁴ (AUTHOR) yi.chengxue@163.com, Akanyibah, Francis Atim¹ (AUTHOR) akanyibahfrancis@gmail.com, Lyu, Changkun⁵ (AUTHOR) lvliang566@163.com, Mao, Fei^1,2 (AUTHOR) maofei2003@ujs.edu.cn

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT‐787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial.

Capozza, Thomas¹ (AUTHOR), Burkey, Jennifer¹ (AUTHOR), Van De Wetering, Jeroen² (AUTHOR), Kerb, Reinhold³ (AUTHOR), Callahan, Jennifer¹ (AUTHOR), Kryzhanovskaya, Ludmila¹ (AUTHOR), Erickson, Mary¹ (AUTHOR) mary.erickson@interceptpharma.com

Research Progress on the Mechanism of Bile Acids and Their Receptors in Depression.

Zhao, Xue¹ (AUTHOR), Zheng, Iin^1,2 (AUTHOR), Huang, Wenjing^1,3 (AUTHOR), Tang, Dongning^1,4 (AUTHOR), Zhao, Meidan^1,2,3,5 (AUTHOR), Hou, Ruiling¹ (AUTHOR), Huang, Ying^1,2 (AUTHOR), Shi, Yun^3,4 (AUTHOR), Zhu, Weili^4,5 (AUTHOR) zhu_wl@bjmu.edu.cn, Wang, Shenjun^1,2,3,5 (AUTHOR) sjwang@tjutcm.edu.cn

Protective Effect of Obeticholic Acid on Sepsis-Induced Liver Dysfunction via Regulating Bile Acid Homeostasis.

Wang, Jiahui¹ (AUTHOR), Ma, Li^1,2 (AUTHOR), An, Yuan¹ (AUTHOR), Ge, Yan^1,2 (AUTHOR), Xu, Dan^1,2 (AUTHOR), Mao, Enqiang¹ (AUTHOR) meq10970@rjh.com.cn

Phenotyping the Chemical Communications of the Intestinal Microbiota and the Host: Secondary Bile Acids as Postbiotics.

Urbani, Ginevra¹ (AUTHOR), Rondini, Elena² (AUTHOR), Distrutti, Eleonora^1,2 (AUTHOR), Marchianò, Silvia^1,2 (AUTHOR), Biagioli, Michele¹ (AUTHOR), Fiorucci, Stefano¹ (AUTHOR) stefano.fiorucci@unipg.it

Farnesoid X Receptor Regulated Sepsis‐Induced Abnormal Bile Acid Metabolism via the Fibroblast Growth Factor 15/Fibroblast Growth Factor Receptor 4 Pathway.

Zhou, Ziyang¹ (AUTHOR), Xu, Dan¹ (AUTHOR), Huang, Liou¹ (AUTHOR), Cui, Yuhui¹ (AUTHOR), Chen, Hui² (AUTHOR), Tang, Jianguo¹ (AUTHOR) tangjg_2094@163.com

Gut Microbiota and Its Metabolite Taurine- β -Muricholic Acid Contribute to Antimony- and/or Copper-Induced Liver Inflammation.

Wu, Dandan¹ (AUTHOR), Lin, Qiwen¹ (AUTHOR), Hou, Senao¹ (AUTHOR), Cui, Xiaorui¹ (AUTHOR), Shou, Na¹ (AUTHOR), Yuan, Xuefeng¹ (AUTHOR), Xu, Wenqian¹ (AUTHOR), Fu, Keyi¹ (AUTHOR), Wang, Qi¹ (AUTHOR), Shi, Zunji¹ (AUTHOR) shizj@lzu.edu.cn

Gut microbiota-mediated bile acid transformations regulate the transport of aflatoxin B1 from the intestine to the liver in piglets.

Mao, Jiangdi¹ (AUTHOR), Wei, Yusen¹ (AUTHOR), Ni, Zhixiang¹ (AUTHOR), Zhang, Jinzhi¹ (AUTHOR), Zhu, Junli² (AUTHOR), Wang, Haifeng¹ (AUTHOR) haifengwang@zju.edu.cn

27-Hydroxymangiferolic Acid Extends Lifespan and Improves Neurodegeneration in Caenorhabditis elegans by Activating Nuclear Receptors.

Gao, Xiaoyan¹ (AUTHOR), Yu, Jing^1,2 (AUTHOR), Li, Yin^1,2 (AUTHOR), Shi, Hang^1,2 (AUTHOR), Zhang, Lijun¹ (AUTHOR), Fang, Minglv¹ (AUTHOR), Liu, Ying¹ (AUTHOR), Huang, Cheng¹ (AUTHOR) chuang@shutcm.edu.cn, Fan, Shengjie¹ (AUTHOR) shengjiefan@shutcm.edu.cn

Farnesoid X Receptor Attenuates the Tumorigenicity of Liver Cancer Stem Cells by Inhibiting STAT3 Phosphorylation.

Ye, Wenling^1,2 (AUTHOR), Zhao, Yang² (AUTHOR), Wang, Yibo² (AUTHOR), Wang, Yahan² (AUTHOR), Zhang, Huan² (AUTHOR), Wang, Fengling^1,2 (AUTHOR) wangfl@henu.edu.cn, Chen, Weidong^1,2 (AUTHOR) wangfl@henu.edu.cn

FXR promotes clear cell renal cell carcinoma carcinogenesis via MMP-7-regulated EMT pathway.

Liu, Jiachen^1,2,3,4 (AUTHOR), Huang, Shiyu^1,2 (AUTHOR), Hou, Yanguang⁵ (AUTHOR), Fu, Shujie^1,2 (AUTHOR), Wang, Lei^1,2 (AUTHOR), Hu, Juncheng^1,2 (AUTHOR) hujc@whu.edu.cn, Liu, Cheng⁶ (AUTHOR) 2013103020057@whu.edu.cn, Liu, Xiuheng^1,2 (AUTHOR) drliuxh@hotmail.com

The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet.

Hwang, Jiyeon^1,2 (AUTHOR), Okada, Junichi^1,2 (AUTHOR), Liu, Li^1,2 (AUTHOR), Pessin, Jeffrey E.^1,2,3 (AUTHOR), Schwartz, Gary J.^1,2 (AUTHOR), Jo, Young-Hwan^1,2,3,4 (AUTHOR) young-hwan.jo@einsteinmed.edu

Activation of Nrf2 and FXR via Natural Compounds in Liver Inflammatory Disease.

Belka, Marta^1,2 (AUTHOR) mbelka@ump.edu.pl, Gostyńska-Stawna, Aleksandra³ (AUTHOR) agostynska@ump.edu.pl, Stawny, Maciej³ (AUTHOR) mstawny@ump.edu.pl, Krajka-Kuźniak, Violetta¹ (AUTHOR) vkrajka@ump.edu.pl

Silibinin, a commonly used therapeutic agent for non‐alcohol fatty liver disease, functions through upregulating intestinal expression of fibroblast growth factor 15/19.

Bai, Yujie¹ (AUTHOR), Zhang, Jing¹ (AUTHOR), Li, Jialin¹ (AUTHOR), Liao, Minghui¹ (AUTHOR), Zhang, Yajing¹ (AUTHOR), Xia, Yufeng¹ (AUTHOR) yfxiacpu@126.com, Wei, Zhifeng¹ (AUTHOR) zhifeng-wei@hotmail.com, Dai, Yue¹ (AUTHOR) yuedaicpu@cpu.edu.cn

Farnesoid X receptor: From Structure to Function and Its Pharmacology in Liver Fibrosis.

Chuan Ding^1,2, Zeping Wang¹, Xinyue Dou¹, Qiao Yang¹, Yan Ning¹, Shi Kao¹, Xianan Sang¹, Min Hao¹, Kuilong Wang¹, Mengyun Peng¹, Shuosheng Zhang³ zhangshuosheng@aliyun.com, Xin Han^1,2 xinhan@zcmu.edu.cn, Gang Cao^1,2 caogang33@163.com

Correction to: Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling.

Zhang, Wanru¹ (AUTHOR), Qin, Xiali¹ (AUTHOR), Zhang, Kexin¹ (AUTHOR), Ma, Jiahui¹ (AUTHOR), Li, Mengfan¹ (AUTHOR), Jin, Ge¹ (AUTHOR), Liu, Xiang¹ (AUTHOR), Wang, Sinan¹ (AUTHOR), Wang, Bangmao¹ (AUTHOR), Wu, Jing² (AUTHOR) wujing36youyi@ccmu.edu.cn, Liu, Tianyu¹ (AUTHOR) liutianyu@tmu.edu.cn, Zhong, Weilong¹ (AUTHOR) zhongweilong@tmu.edu.cn, Cao, Hailong¹ (AUTHOR) caohailong@tmu.edu.cn

Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling.

Zhang, Wanru¹ (AUTHOR), Qin, Xiali¹ (AUTHOR), Zhang, Kexin¹ (AUTHOR), Ma, Jiahui¹ (AUTHOR), Li, Mengfan¹ (AUTHOR), Jin, Ge¹ (AUTHOR), Liu, Xiang¹ (AUTHOR), Wang, Sinan¹ (AUTHOR), Wang, Bangmao¹ (AUTHOR), Wu, Jing² (AUTHOR) wujing36youyi@ccmu.edu.cn, Liu, Tianyu¹ (AUTHOR) liutianyu@tmu.edu.cn, Zhong, Weilong¹ (AUTHOR) zhongweilong@tmu.edu.cn, Cao, Hailong¹ (AUTHOR) caohailong@tmu.edu.cn

Emodin alleviates cholestatic liver injury by modulating Sirt1/Fxr signaling pathways.

Hu, Zhi¹ (AUTHOR), Cheng, Xiaohua¹ (AUTHOR), Cai, Jun¹ (AUTHOR), Huang, Chao² (AUTHOR), Hu, Jinfang¹ (AUTHOR) hujinfang333@126.com, Liu, Jianming¹ (AUTHOR) liujianming390@163.com

The GLP-1 Receptor Agonist Liraglutide Decreases Primary Bile Acids and Serotonin in the Colon Independently of Feeding in Mice.

Nonogaki, Katsunori¹ (AUTHOR) katsu@tohoku.ac.jp, Kaji, Takao¹ (AUTHOR)