Sökresultat - "interleukin"

The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway.

Ding C; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China., Gao H; Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China., Zhang L; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China., Lu Z; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China., Zhang B; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China., Li D; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China., Sun F; Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China. sunfengyin@qiluhospital.com.

Journal Article , 2025

Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.

Wu Z; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Wu X; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Meng X; Department of Neurosurgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200092, China., Lei J; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Zeng C; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Pu H; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Liu Y; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Xu Z; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University. Shanghai 200240, China., Wu X; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Huang S; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Electronic address: shenghuang@sh9hospital.org.cn., Qin J; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Liu J; Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, and School of Pharmacy, Guangdong Medical University, Dongguan 523808, China. Electronic address: jianqiangliu8@gdmu.edu.cn., Lu X; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Electronic address: luxinwu@shsmu.edu.cn., Li B; Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Electronic address: boli@shsmu.edu.cn.

Journal Article , 2025

Four months of treatment with anakinra combined with glucocorticoids for giant cell arteritis: a multicenter, randomized, double-blind, placebo-controlled trial.

de Boysson H; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France.; University of Caen Normandie, Caen, 14000, France., Ly KH; Department of Internal Medicine, Limoges University Hospital, 2 Avenue Martin Luther King, Limoges, 87000, France., Geffray L; Department of Internal Medicine, Lisieux Hospital, 4 Rue Roger Aini, Lisieux, 14100, France., Quemeneur T; Department of Internal Medicine, Valenciennes Hospital, 114 Avenue Desandrouin, Valenciennes, 59300, France., Liozon E; Department of Internal Medicine, Limoges University Hospital, 2 Avenue Martin Luther King, Limoges, 87000, France., Bezanahary H; Department of Internal Medicine, Limoges University Hospital, 2 Avenue Martin Luther King, Limoges, 87000, France., Gouellec NL; Department of Internal Medicine, Valenciennes Hospital, 114 Avenue Desandrouin, Valenciennes, 59300, France., Audemard A; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Dumont A; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Deshayes S; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France.; University of Caen Normandie, Caen, 14000, France., Boutemy J; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Maigné G; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Martin Silva N; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Sultan A; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Le Mauff B; University of Caen Normandie, Caen, 14000, France.; Department of Immunology and Histocompatibility (HLA), Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Petit G; Department of Immunology and Histocompatibility (HLA), Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Parienti JJ; University of Caen Normandie, Caen, 14000, France.; Department of Clinical Research and Biostatistics, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France., Aouba A; Department of Internal Medicine, Caen University Hospital, Avenue de la Côte de Nacre, Caen, 14000, France. aouba-a@chu-caen.fr.; University of Caen Normandie, Caen, 14000, France. aouba-a@chu-caen.fr.

Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III , 2025

A phase 1 clinical trial shows safe, sustained, AAV-mediated expression of IL-1Ra in the human osteoarthritic knee joint.

De la Vega RE; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Musculoskeletal Gene Therapy Laboratory, Mayo Clinic, Rochester, MN 55905, USA., Sellon JL; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA., Smith J; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Wisniewski SJ; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Jurisson ML; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Frick MA; Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA., Scrabeck TL; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Block JB; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Mills CJ; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA., Pohlkamp ZW; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA., Coenen MJ; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Musculoskeletal Gene Therapy Laboratory, Mayo Clinic, Rochester, MN 55905, USA., Hawse GP; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Musculoskeletal Gene Therapy Laboratory, Mayo Clinic, Rochester, MN 55905, USA., Abdul TY; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Musculoskeletal Gene Therapy Laboratory, Mayo Clinic, Rochester, MN 55905, USA.; Department of Clinical Pharmacology, Mayo Clinic, Rochester, MN 55905, USA., Conaghan P; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds LS7 4SA, UK., Keravala A; Genascence Corp., Palo Alto, CA 94306, USA., Chalberg TW; Genascence Corp., Palo Alto, CA 94306, USA., Robbins PD; Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA., Ghivizzani SC; Department of Orthopedics and Rehabilitation, University of Florida College of Medicine, Gainesville, FL 32610, USA., Evans CH; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Musculoskeletal Gene Therapy Laboratory, Mayo Clinic, Rochester, MN 55905, USA.; Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.

Journal Article; Clinical Trial, Phase I , 2025

The E3 ligase TRIM21 promotes progression of pancreatic ductal adenocarcinoma by down-regulating TAp63α and derepressing IL20RB .

Li Z; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Gao F; Liver Transplantation Center, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu 610041, Sichuan, China., Liu X; College of Life Sciences, China West Normal University, Nanchong 637009, Sichuan, China., Fan S; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Qi Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., He M; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Luo X; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Nie X; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Wang J; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Wang Y; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Xiao ZJ; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China., Li C; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan, China.

Journal Article , 2025

A hybrid protocol for peptide development: integrating deep generative models and physics simulations for biomolecular design targeting IL23R/IL23.

Qayyum N; Department of Molecular Science and Technology, Ajou University, Suwon 16499, South Korea. Electronic address: nailaqayyum16@ajou.ac.kr., Seo H; Department of Molecular Science and Technology, Ajou University, Suwon 16499, South Korea., Khan N; Department of Computer Science, Yonsei University, Seoul 03722, South Korea., Manan A; Department of Molecular Science and Technology, Ajou University, Suwon 16499, South Korea., Ramachandran R; Department of Molecular Science and Technology, Ajou University, Suwon 16499, South Korea., Haseeb M; S&K Therapeutics, Ajou University Campus Plaza 418, Worldcup-ro 199, Yeongtong-gu, Suwon 16502, South Korea., Kim E; Department of Molecular Science and Technology, Ajou University, Suwon 16499, South Korea., Choi S; S&K Therapeutics, Ajou University Campus Plaza 418, Worldcup-ro 199, Yeongtong-gu, Suwon 16502, South Korea. Electronic address: sangdunchoi@ajou.ac.kr.

Journal Article , 2025

Targeting the IL-23 Receptor Gene: A Promising Approach in Inflammatory Bowel Disease Treatment.

Pastras P; Division of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece., Aggeletopoulou I; Division of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece., Papantoniou K; Division of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece., Triantos C; Division of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece.

Journal Article; Review , 2025

Single-cell dynamics of breakthrough toxicities after anakinra prophylaxis for axicabtagene ciloleucel in lymphoma.

Frigault MJ; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., Yao N; Harvard Medical School, Boston, MA., Berger TR; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Wehrli M; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Gallagher KME; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Horick N; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Graham CE; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Jacobson CA; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA.; Dana-Farber Cancer Institute, Department of Hematology/Oncology, Boston, MA., Chen YB; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., Leick MB; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., DeFilipp Z; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., El-Jawahri AR; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., Johnson PC; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., Dolaher M; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Katsis K; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Kim AI; Harvard Medical School, Boston, MA.; Dana-Farber Cancer Institute, Department of Hematology/Oncology, Boston, MA., Crombie J; Harvard Medical School, Boston, MA.; Dana-Farber Cancer Institute, Department of Hematology/Oncology, Boston, MA., Merryman RW; Harvard Medical School, Boston, MA.; Dana-Farber Cancer Institute, Department of Hematology/Oncology, Boston, MA., Cook D; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Trailor M; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Cho H; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Jeffrey R 3rd; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA., Shen R; Kite, a Gilead Company, Santa Monica, CA., Filosto S; Kite, a Gilead Company, Santa Monica, CA., Nater J; Kite, a Gilead Company, Santa Monica, CA., Getz G; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA., Haradhvala NJ; Harvard Medical School, Boston, MA., Maus MV; Cellular Immunotherapy Program, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA.; Cancer Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.; Harvard Medical School, Boston, MA.

Clinical Trial, Phase II; Journal Article; Multicenter Study , 2025

Protective Effects of Interleukin-1 Inhibition With Anakinra in Mouse Models of Ischemic Stroke With and Without Reperfusion.

Chaparro-Cabanillas N; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Universitat de Barcelona Barcelona Spain., Aliena-Valero A; Unidad Mixta de Investigación Cerebrovascular Instituto de Investigación Sanitaria La Fe-Universidad de Valencia València Spain., Pedragosa J; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain., Pedrosa L; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain., Honores M; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain., Rossinyol-Boladeres M; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Universitat Autònoma de Barcelona Barcelona Spain., Salom JB; Unidad Mixta de Investigación Cerebrovascular Instituto de Investigación Sanitaria La Fe-Universidad de Valencia València Spain.; Departamento de Fisiología Universidad de Valencia València Spain., Chamorro Á; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain.; Servei de Neurologia Hospital Clínic Barcelona Spain., Arostegui JI; Universitat de Barcelona Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain.; Servei d'Immunologia Hospital Clínic Barcelona Spain., Urra X; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain.; Servei de Neurologia Hospital Clínic Barcelona Spain., Justicia C; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain., Planas AM; Departament de Neurociències i Terapèutica Experimental Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC Barcelona Spain.; Universitat de Barcelona Barcelona Spain.; Fundació de Recerca Clínic Barcelona-IDIBAPS Barcelona Spain.

Journal Article , 2025

Co-delivery of IL-1Ra and SOX9 via AAV inhibits inflammation and promotes cartilage repair in surgically induced osteoarthritis animal models.

Zhou K; School of Pharmacy, East China University of Science and Technology, Shanghai, China., Yuan M; School of Pharmacy, East China University of Science and Technology, Shanghai, China., Sun J; School of Pharmacy, East China University of Science and Technology, Shanghai, China., Zhang F; State Key Laboratory of Bioreactor Engineering, School of Biotechnology, East China University of Science and Technology, Shanghai, China., Li X; State Key Laboratory of Bioreactor Engineering, School of Biotechnology, East China University of Science and Technology, Shanghai, China., Xiao X; School of Pharmacy, East China University of Science and Technology, Shanghai, China. xiaoxiao2018aav@163.com.cn.; State Key Laboratory of Bioreactor Engineering, School of Biotechnology, East China University of Science and Technology, Shanghai, China. xiaoxiao2018aav@163.com.cn., Wu X; School of Pharmacy, East China University of Science and Technology, Shanghai, China. wuxia@ecust.edu.cn.

Journal Article , 2025

Evaluation of Novel Therapeutic Agents for Modulation of the Inflammatory Response in Rotator Cuff Tendinopathy Utilizing a Mouse Model of Subacromial Impingement.

Eliasberg CD; Sports Medicine Institute, Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.; Orthopaedic Soft Tissue Research Program, Hospital for Special Surgery Research Institute, New York, New York, USA., Carballo CB; Orthopaedic Soft Tissue Research Program, Hospital for Special Surgery Research Institute, New York, New York, USA., J H Yao V; City University of New York, School of Medicine, New York, New York, USA., Piacentini A; Orthopaedic Soft Tissue Research Program, Hospital for Special Surgery Research Institute, New York, New York, USA., Sanchez LA; Weill Cornell Medical College, New York, New York, USA., Li TM; University of California, San Francisco, San Francisco, California, USA., Havasy J; Long Island Jewish Medical Center/North Shore University Hospital, New York, New York, USA., Bowen EG; Rush University, Chicago, Illinois, USA., Khan M; University of Florida, Gainesville, Florida, USA., Rodeo SA; Sports Medicine Institute, Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.; Orthopaedic Soft Tissue Research Program, Hospital for Special Surgery Research Institute, New York, New York, USA.

Journal Article , 2025

Immune dysregulation in endometrial tuberculosis: elevated HLA-G and IL-1Ra as key modulators.

Huang D; Graduate School of Hebei North University, Zhangjiakou, China.; Department of Reproductive Medicine Clinic, The Eighth Medical Center, Chinese PLA General Hospital, Beijing, China., Dai J; Department of Pathology, The Eighth Medical Center, Chinese PLA General Hospital, Beijing, China., Yu H; Department of Reproductive Medicine Clinic, The Eighth Medical Center, Chinese PLA General Hospital, Beijing, China., Chen W; Department of Pathology, The Eighth Medical Center, Chinese PLA General Hospital, Beijing, China.

Journal Article , 2025

Off-Label Use of Anakinra in Inflammatory Conditions in Neonates and Infants Up to 3 Months of Age: A Case Series and a Review of the Literature.

De Rose DU; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy.; Microbiology, Immunology, Infectious Diseases, and Transplants (MIMIT), Faculty of Medicine and Surgery, 'Tor Vergata' University of Rome, Rome, Italy., Campi F; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Maddaloni C; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Ronci S; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy. sara.ronci@opbg.net., Caoci S; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Savarese I; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Bersani I; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Ronchetti MP; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Auriti C; Saint Camillus International University of Health Sciences, Rome, Italy., Capolupo I; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy., Merli P; Hematology and Oncology Unit, 'Bambino Gesù' Children's Hospital IRCCS, Rome, Italy., Insalaco A; Rheumatology Unit, 'Bambino Gesù' Children Hospital IRCSS, Rome, Italy., De Benedetti F; Rheumatology Unit, 'Bambino Gesù' Children Hospital IRCSS, Rome, Italy., Dotta A; Neonatal Intensive Care Unit-'Bambino Gesù' Children's Hospital IRCCS, 00165, Rome, Italy.

Journal Article; Review; Case Reports , 2025

Efficacy and Safety of Anakinra in Colchicine-Resistant or -Intolerant Familial Mediterranean Fever: A Single-Center Real-Life Experience.

Ocak T; Department of Rheumatology, Bursa City Hospital, 16250 Bursa, Turkey., Köse HN; Department of Internal Medicine, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey., Yağız B; Department of Rheumatology, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey., Coşkun BN; Department of Rheumatology, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey., Dalkılıç E; Department of Rheumatology, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey., Pehlivan Y; Department of Rheumatology, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey.

Journal Article , 2025

Comparison of IL-1 Receptor Antagonist and Dexamethasone in Noise-Induced Hearing Loss: Animal Model.

Yaşar NG; Department of Otolaryngology-Head and Neck Surgery, Ankara City Hospital, Ankara, Turkey., Yiğman Z; Department of Histology and Embryology, Gazi University Faculty of Medicine, Ankara, Turkey.; Neuroscience and Neurotechnology Center of Excellence NOROM, Gazi University, Ankara, Turkey., Billur D; Department of Histology and Embryology, Ankara University Faculty of Medicine, Ankara, Turkey., Tufan A; Department of Internal Medicine, Division of Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey.; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Gündüz B; Department of Audiology, Gazi University Faculty of Health Sciences, Ankara, Turkey., Kamişli GIŞ; Department of Audiology, Gazi University Faculty of Health Sciences, Ankara, Turkey., Karamert R; Department of Otorhinolaryngology, Gazi University Faculty of Medicine, Ankara, Turkey.

Journal Article; Comparative Study , 2025

[Combination therapy with rituximab and anakinra in the treatment of chronic pericarditis complicating rheumatoid arthritis].

Belfeki N; Service de Médecine Interne et Immunologie Clinique. Groupe Hospitalier Sud Ile de France, Melun, France. Electronic address: nabil.belfeki@ghsif.fr., Ghriss N; Service de Médecine Interne et Immunologie Clinique. Groupe Hospitalier Sud Ile de France, Melun, France., Hamrouni H; Service d'Imagerie Médicale. Groupe Hospitalier Sud Ile de France, Melun, France., Kammoun S; Service de Médecine Interne et Immunologie Clinique. Groupe Hospitalier Sud Ile de France, Melun, France., Alloujami M; Service de Cardiologie. Groupe Hospitalier Sud Ile de France, Melun, France., Moini C; Service de Cardiologie. Groupe Hospitalier Sud Ile de France, Melun, France.

Journal Article; Case Reports; English Abstract , 2025

Interleukin-1 Receptor Antagonists Partially Inhibited Histological Injury but Not Tissue Inflammation in a Sheep Model of Pregnancy.

Takahashi Y; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan. yuki.s0618@gmail.com.; Department of Obstetrics, Tohoku University, 1-1 Seiryomachi Aobaku, Sendai, Miyagi, Japan. yuki.s0618@gmail.com., Fee EL; Division of Obstetrics and Gynecology, The University of Western Australia, Perth, Western Australia, Australia., Takahashi T; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan., Usuda H; Division of Obstetrics and Gynecology, The University of Western Australia, Perth, Western Australia, Australia., Ikeda H; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan., Carter SW; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Saito Y; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan., Sato S; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan., Mochii N; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan., Chemtob S; Department of Pharmacology and Physiology, University of Montreal, Montreal, Canada., Olson DM; Departments of Obstetrics and Gynecology, Pediatrics, and Physiology, University of Alberta, Alberta, Canada., Keelan JA; Division of Obstetrics and Gynecology, The University of Western Australia, Perth, Western Australia, Australia., Kumagai Y; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Obstetrics, Tohoku University, 1-1 Seiryomachi Aobaku, Sendai, Miyagi, Japan., Choolani MA; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Illanes SE; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Obstetrics and Gynaecology, University of the Andes, Santiago, Chile.; IMPACT, Center of Interventional Medicine for Precision and Advanced Cellular Therapy, Santiago, Chile., Saito M; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan.; Department of Obstetrics, Tohoku University, 1-1 Seiryomachi Aobaku, Sendai, Miyagi, Japan., Kemp MW; Centre for Perinatal and Neonatal Medicine, Tohoku University Hospital, Sendai, Japan.; Division of Obstetrics and Gynecology, The University of Western Australia, Perth, Western Australia, Australia.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; School of Veterinary and Life Sciences, Murdoch University, Perth, Australia.; Women and Infants Research Foundation, Level 2, Carson House, King Edward Memorial Hospital, Perth, Australia.

Journal Article , 2025

Long-term efficacy and safety of colchicine and anti-IL-1 blockers in FMF: results from the Eurofever multicenter observational study.

Bustaffa M; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genova, Italy., Bella S; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genova, Italy., Bayindir Y; Hacettepe University Faculty of Medicine, Department of Pediatric Rheumatology, Ankara, Turkey., Amaryan G; Arabkir Medical Complex - Institute of Child and Adolescent Health, National Pediatric Centre for Familial Mediterranean Fever, Yerevan State Medical University, Yerevan, Armenia., Gallizzi R; Magna Graecia University, Department of Medical of Health Sciences, Catanzaro, Italy., Papadopoulou-Alataki E; Papageorgiou Hospital, 4th Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece., Fabio G; Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy., Assalia N; Schneider Children's Medical Center of Israel, Pediatric Rheumatology Unit, Petach-Tikvah, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Israel., Amarilyo G; Schneider Children's Medical Center of Israel, Pediatric Rheumatology Unit, Petach-Tikvah, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Israel., Bakkaloglu S; Gazi University Faculty of Medicine, Pediatric Rheumatology, Ankara, Turkey., Jesenak M; Jesenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, National Centre for Periodic Fever Syndromes, Department of Paediatrics and Adolescent Medicine, Department of Pulmonology and Phthisiology, Institute of Clinical Immunology and Medical Genetics, Martin, Slovakia., Breda L; Ospedale Policlinico - Università degli studi di Chieti, Dipartimento di Pediatria, Chieti, Italy., Anton J; Hospital Sant Joan de Déu, ERN-RITA Center, Department of Pediatric Rheumatology, Universitat de Barcelona, Barcelona, Spain., Legger E; Pediatric Rheumatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Alessio M; Department of Translational Medical Science, Federico II University of Naples, Italy., Simonini G; IRCCS Meyer Children's Hospital, Rheumatology Unit, ERN-ReCONNECT Center, Florence, Italy., Rigante D; Department of Life Sciences and Public Health, Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica Sacro Cuore, Rome, Italy., Obici L; Fondazione IRCCS Policlinico San Matteo, UOS Malattie Rare and Amyloidosis Research and Treatment Centre, Pavia, Italy., Kuemmerle-Deschner J; University Hospital Tuebingen, Department of Pediatrics, Division of Pediatric Rheumatology and Autoinflammation Reference Center, Tuebingen, Germany., Kasapcopur O; Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey., Insalaco A; IRCCS Ospedale Pediatrico Bambino Gesù, ERN-RITA Center, Division of Rheumatology, Rome, Italy., Glerup M; Aarhus University Hospital, The Department of Paediatrics and Adolescent Medicine, Aarhus, Denmark; Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark., Frenkel J; Wilhelmina Children's Hospital, Department of Pediatric Immunology and Rheumatology, Utrecht, the Netherlands., Brunner J; Department of Pediatrics, Pediatric Rheumatology, Medical University Innsbruck, Innsbruck and Department of Dentistry, Faculty of Medicine and Dentistry, Danube Private University Krems, Austria., Horneff G; Asklepios Clinic Sankt Augustin, Department of General Paediatrics, Sankt Augustin, Germany; University Hospital of Cologne, Medical Faculty, Department of Paediatric and Adolescents Medicine, Cologne, Germany., Sánchez-Manubens J; Pediatric Rheumatology, Department of Pediatrics, Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA). Universitat Autonoma de Barceona, Sabadell, Spain., Cantarini L; University of Siena, Department of Medical Sciences, Surgery and Neurosciences, Rheumatology Unit, Siena, Italy., Spagnolo A; Magna Graecia University, Department of Medical of Health Sciences, Catanzaro, Italy., Alataki S; Papageorgiou Hospital, 4th Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece., Carrabba M; Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy., Belder N; Gazi University Faculty of Medicine, Pediatric Rheumatology, Ankara, Turkey., Porreca A; Department for the Promotion of Human Science and Quality of Life, San Raffaele University, Rome, Italy., Caorsi R; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genova, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Università degli Studi di Genova, Genova, Italy., Ruperto N; Fondazione IRCCS San Gerardo dei Tintori di Monza, Reumatologia Pediatrica, Monza, Italy; Università degli Studi di Milano-Bicocca, Pediatria, Milan, Italy., Gattorno M; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genova, Italy. Electronic address: marcogattorno@gaslini.org., Ozen S; Hacettepe University Faculty of Medicine, Department of Pediatric Rheumatology, Ankara, Turkey.

Eurofever Registry

Journal Article; Observational Study; Multicenter Study , 2025

Reduced interleukin-2 receptor subunit γ expression in Crohn's disease: A potential mechanism for γδ T cell deficiency.

Hussain MS; Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehra Dun 248007, Uttarākhand, India. sadiquehussain007@gmail.com., Bisht AS; School of Pharmaceutical Sciences, Shri Guru Ram Rai University, Dehra Dun 248001, Uttarākhand, India., Gupta G; Centre for Research Impact & Outcome-Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India.; Centre of Medical and Bio-allied Health Sciences Research, Ajman University, Al Jerf 00000, Ajman, United Arab Emirates.

Journal Article; Letter , 2025

Combined Systemic Immunotherapy and Intrathecal Dexamethasone in Febrile Infection Related Epilepsy Syndrome.

Fisher KS; Division of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Ankar A; Division of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Cokley J; Department of Pharmacy, Texas Children's Hospital, Houston, Texas, USA., Muscal E; Division of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.; Division of Rheumatology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Riviello JJ; Division of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Lai YC; Division of Pediatric Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine at Texas Children's Hospital, Houston, Texas, USA.

Journal Article; Case Reports , 2025