Search Results - "mitochondrial permeability transition pore"

Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction.

Ni R; International Genome Center, Jiangsu University, Zhenjiang, 212013, China.; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada., Ji XY; International Genome Center, Jiangsu University, Zhenjiang, 212013, China.; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada., Cao T; Institutes of Biology and Medical Sciences and Institute for Cardiovascular Science, Soochow University, Suzhou, 215123, China., Liu XW; Affiliated Hospital, Jiangsu University, Zhenjiang, 212013, China.; School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Wang C; International Genome Center, Jiangsu University, Zhenjiang, 212013, China.; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada., Lu C; Department of Chemical and Biochemical Engineering, Western University, London, ON, Canada., Peng A; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada., Zhang ZX; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada.; Department of Medicine, Western University, London, ON, Canada., Fan GC; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Zhang J; Department of Chemical and Biochemical Engineering, Western University, London, ON, Canada., Su ZL; International Genome Center, Jiangsu University, Zhenjiang, 212013, China. szl30@ujs.edu.cn., Peng TQ; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada. tpeng2@uwo.ca.; Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada. tpeng2@uwo.ca.; Department of Medicine, Western University, London, ON, Canada. tpeng2@uwo.ca.

Journal Article , 2025

Inhibition of the mitochondrial permeability transition pore as a promising target for protecting auditory function in cisplatin-induced hearing loss.

Kim YR; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea; Advanced Bio-Resource Research Center, Kyungpook National University, Daegu, Republic of Korea., Jun S; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea; School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea., Jung S; Department of Applied Chemistry, Center for Bionano Intelligence Education and Research, Hanyang University ERICA, Ansan, Republic of Korea., Lee B; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (KMEDI-Hub), Daegu, Republic of Korea., Lee SH; Center of Research Equipment (104-Dong), Korea Basic Science Institute, Ochang, Cheongju, Chungbuk 28119, Republic of Korea., Lee J; Advanced Bio-Resource Research Center, Kyungpook National University, Daegu, Republic of Korea., Hwang JS; Advanced Bio-Resource Research Center, Kyungpook National University, Daegu, Republic of Korea., Thoudam T; Research Institute of Aging and Metabolism, Kyungpook National University, Daegu 41404, Republic of Korea., Lee H; Research Institute of Aging and Metabolism, Kyungpook National University, Daegu 41404, Republic of Korea., Sinam IS; Bio-Medical Research Institute, Kyungpook National University Hospital, Daegu, Republic of Korea., Jeon JH; Research Institute of Aging and Metabolism, Kyungpook National University, Daegu 41404, Republic of Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu 41404, Republic of Korea., Lee KY; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea. Electronic address: kylee@knu.ac.kr., Min SJ; Department of Applied Chemistry, Center for Bionano Intelligence Education and Research, Hanyang University ERICA, Ansan, Republic of Korea; Department of Chemical & Molecular Engineering, Hanyang University ERICA, Ansan, Republic of Korea. Electronic address: sjmin@hanyang.ac.kr., Kim UK; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea; School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea. Electronic address: kimuk@knu.ac.kr.

Journal Article , 2025

Inside-out submitochondrial particles affect the mitochondrial permeability transition pore opening under conditions of mitochondrial dysfunction.

Algieri C; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Cugliari A; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Glogowski PA; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Granata S; IRCCS Neuromed, Pozzilli, Italy., Fabbri M; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Trombetti F; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Bacci ML; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy., Nesci S; Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy. Electronic address: salvatore.nesci@unibo.it.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Senolysis by GLS1 Inhibition Ameliorates Kidney Aging by Inducing Excessive mPTP Opening Through MFN1.

Chen Y; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Zhao N; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Zhang Y; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Chen X; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Chen Y; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Wang Y; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Wu J; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Zhao W; Division of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.; Key Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Journal Article , 2025

Differential effects of endo- and exopolyphosphatase expression on the induction of the mitochondrial permeability transition pore.

Akosah Y; Department of Molecular Pathobiology, New York University, New York, NY, USA., Hambardikar V; Department of Biology, Rutgers University, Camden, NJ, USA., Neginskaya M; Department of Molecular Pathobiology, New York University, New York, NY, USA., Morris S; Department of Molecular Pathobiology, New York University, New York, NY, USA., Solesio ME; Department of Biology, Rutgers University, Camden, NJ, USA., Pavlov EV; Department of Molecular Pathobiology, New York University, New York, NY, USA. Electronic address: ep37@nyu.edu.

Journal Article; Research Support, N.I.H., Extramural , 2025

How does mitochondrial Ca2+ change during ischemia and reperfusion? Implications for activation of the permeability transition pore.

Murphy E; Cardiac Physiology Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Eisner DA; Unit of Cardiac Physiology, Division of Cardiovascular Sciences, University of Manchester, Manchester, UK.

Journal Article; Review , 2025

Point of No Return-What Is the Threshold of Mitochondria With Permeability Transition in Cells to Trigger Cell Death.

Kritskaya KA; Institute of Cell Biophysics of the Russian Academy of Sciences, Puschino, Russia., Stelmashchuk OA; Orel State University named after I.S. Turgenev, Orel, Russia., Abramov AY; Orel State University named after I.S. Turgenev, Orel, Russia.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London, UK.

Journal Article , 2025

CgANT2 regulates mitophagy of oyster haemocyte response against bacterial stimulation.

Wu W; School of Life Science, Liaoning Normal University, Dalian, 116029, China; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Lv X; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Sun J; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Wang Z; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Dong M; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Wang L; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Song L; Liaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian, 116023, China; Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China. Electronic address: lshsong@dlou.edu.cn.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Modulation of mitochondrial permeability transition pores in reperfusion injury: Mechanisms and therapeutic approaches.

Morciano G; Department of Medical Sciences, University of Ferrara, Ferrara, Italy.; Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy., Pinton P; Department of Medical Sciences, University of Ferrara, Ferrara, Italy.; Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.

Journal Article; Review , 2025

The Role of Mitochondrial Permeability Transition in Bone Metabolism, Bone Healing, and Bone Diseases.

Zhu X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Qin Z; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Zhou M; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Li C; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Jing J; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Ye W; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China., Gan X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Journal Article; Review , 2024

A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore.

Vanderhaeghe S; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.; Laboratory of Neurobiology, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; reMYND, Leuven, Belgium., Prerad J; reMYND, Leuven, Belgium., Tharkeshwar AK; Department of Human Genetics, KU Leuven - University of Leuven, Leuven, Belgium.; KU Leuven Institute for Single Cell Omics (LISCO), KU Leuven - University of Leuven, Leuven, Belgium., Goethals E; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.; reMYND, Leuven, Belgium., Vints K; Electron Microscopy Platform and VIB-Bioimaging Core, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Beckers J; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.; Laboratory of Neurobiology, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Scheveneels W; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.; Laboratory of Neurobiology, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Debroux E; reMYND, Leuven, Belgium., Princen K; reMYND, Leuven, Belgium., Van Damme P; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium., Fivaz M; reMYND, Leuven, Belgium. marc.fivaz@remynd.com., Griffioen G; reMYND, Leuven, Belgium. gerard.griffioen@ext.remynd.com., Van Den Bosch L; Laboratory of Neurobiology, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium. ludo.vandenbosch@kuleuven.be.; Laboratory of Neurobiology, VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium. ludo.vandenbosch@kuleuven.be.

Journal Article , 2024

The adenine nucleotide translocase family underlies cardiac ischemia-reperfusion injury through the mitochondrial permeability pore independently of cyclophilin D.

Patel P; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA., Mendoza A; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA., Ramirez D; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA., Robichaux D; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA., Molkentin JD; Department of Pediatrics, Cincinnati Children's Hospital and the University of Cincinnati, Cincinnati, OH, USA., Karch J; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA.; The Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA.

Journal Article , 2024

Naringin alleviates fluoride-induced neurological impairment: A focus on the regulation of energy metabolism mediated by mitochondrial permeability transition pore.

Du Y; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China; School of Water Conservancy Science and Engineering, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address: duyuhui@zzu.edu.cn., Wang G; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address: wgq1001@gs.zzu.edu.cn., Liu B; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China., Guo M; Wuhan Asia Heart Hospital, Wuhan, Hubei 430000, China., Yan X; Department of Neurology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan 450001, China., Dou M; School of Water Conservancy Science and Engineering, Zhengzhou University, Zhengzhou, Henan 450001, China., Yu F; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address: yufangfang@zzu.edu.cn., Ba Y; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China; National Health Commission Key Laboratory of Birth Defects Prevention, Henan Key Laboratory of Population Defects Prevention, Zhengzhou, Henan 450001, China. Electronic address: byyue@zzu.edu.cn., Zhou G; Department of Environmental Health & Environment and Health Innovation Team, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China; National Health Commission Key Laboratory of Birth Defects Prevention, Henan Key Laboratory of Population Defects Prevention, Zhengzhou, Henan 450001, China. Electronic address: zhouguoyu@zzu.edu.cn.

Journal Article , 2024

Double Braking Effects of Nanomedicine on Mitochondrial Permeability Transition Pore for Treating Idiopathic Pulmonary Fibrosis.

Lu A; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Xu Z; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Zhao Z; Department of Pharmacy, Clinical Trial Research Center, China-Japan Friendship Hospital, Beijing, 100029, China., Yan Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Jiang L; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Geng J; National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, 100029, China., Jin H; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Wang X; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Liu X; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Zhu Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Shi Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China., Liu L; Department of Pharmacy, Clinical Trial Research Center, China-Japan Friendship Hospital, Beijing, 100029, China., Dai H; National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, 100029, China., Wang JC; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.; Laboratory of Innovative Formulations and Pharmaceutical Excipients, Peking University Ningbo Institute of Marine Medicine, Ningbo, 315832, China.

Journal Article , 2024

Cyclophilin D plays a critical role in the survival of senescent cells.

Protasoni M; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain.; Cambridge Institute of Science, Altos Labs, Granta Park, Cambridge, CB21 6GP, UK., López-Polo V; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain., Stephan-Otto Attolini C; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain., Brandariz J; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Herranz N; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain., Mateo J; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Vall d'Hebron University Hospital, Barcelona, Spain., Ruiz S; Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, 20814, USA., Fernandez-Capetillo O; Spanish National Cancer Research Center (CNIO), 28028, Madrid, Spain.; Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Kovatcheva M; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain. marta.kovatcheva@ifom.eu.; IFOM ETS-The AIRC Institute of Molecular Oncology, Milan, Italy. marta.kovatcheva@ifom.eu., Serrano M; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain. mserrano@altoslabs.com.; Cambridge Institute of Science, Altos Labs, Granta Park, Cambridge, CB21 6GP, UK. mserrano@altoslabs.com.

Journal Article , 2024

Cardioprotective Effect of Chronic Hypoxia Involves Inhibition of Mitochondrial Permeability Transition Pore Opening.

Alanova P; Laboratory of Developmental Cardiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic. Petra.Alanova@fgu.cas.cz., Alan L, Neckar J, Ostadal B, Kolar F

Journal Article , 2024

Endogenous complement 1q binding protein (C1qbp) regulates mitochondrial permeability transition and post-myocardial infarction remodeling and dysfunction.

Gutiérrez-Aguilar M; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA; Departamento de Bioquímica, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico., Klutho PJ; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA., Aguayo-Ortiz R; Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico., Song L; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA., Baines CP; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA; Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA; Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO 65211, USA. Electronic address: bainesc@missouri.edu.

Journal Article , 2024

Melatonin attenuates liver ischemia-reperfusion injury via inhibiting the PGAM5-mPTP pathway.

Shi X; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Zhang J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Gao J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Guo D; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Zhang S; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Chen X; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China., Tang H; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Henan Engineering Technology Research Center of Organ Transplantation, Zhengzhou, Henan, China.; ZhengZhou Engineering Laboratory of Organ Transplantation Technique and Application, Zhengzhou, Henan, China.

Journal Article , 2024

Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.

Hu SS; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Wang TY; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Ni L; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Hu FX; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Yue BW; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Zheng Y; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Wang TL; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Kumar A; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Wang YY; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China., Wang JE; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China. wangjinew@163.com.; College of Basic Medical Science, China Three Gorges University, Yichang, 443002, China. wangjinew@163.com., Zhou ZY; Third-grade Pharmacological Laboratory of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China. in_bud@ctgu.edu.cn.; College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, China. in_bud@ctgu.edu.cn.

Journal Article , 2024

CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.

He L; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Lin J; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Lu S; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Li H; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Chen J; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Wu X; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Yan Q; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Liu H; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China.; State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200123, China., Li H; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China., Shi Y; Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China.; Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Tongji University Cancer Center, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, 200092, China.

Journal Article , 2024