Search Results - "off-target effects"

Designing Selective Drugs: Multi-Objective Optimization to Mitigate Off-Target Effects

Shin, Dong-Hee, Son, Young-Han, Lee, Deok-Joong, Kam, Tae-Eui

2025 International Conference on Electronics, Information, and Communication (ICEIC)

CRISPR Off-Target Analysis Platforms

Xu, Christine L.^Aff4, Ruan, Merry Zhechao^Aff5, Ragi, Sara D.^Aff6, Tsang, Stephen H.^Aff7

Tsang, Stephen H.^Aff2, Quinn, Peter M.J.^Aff3, Walker, John M.^Aff1

Methods for Measuring CRISPR/Cas9 DNA Cleavage in Cells

Cromwell, Christopher R.^Aff5, Jovel, Juan^Aff6, Hubbard, Basil P.^Aff5

Fulga, Tudor A.^Aff2, Knapp, David J. H. F.^Aff3, Ferry, Quentin R. V.^Aff4, Walker, John M.^Aff1

Upconversion Core-Shell Nanoconstructs for Cancer Theragnostics

Singh, Aditya^Aff4, Maheshwari, Shubhrat^{Aff5, Aff6}, Vishwakarma, Vishal Kumar^Aff7, Prajapati, Bhupendra^Aff8

Patel, Jayvadan K, editor^Aff1, Dhas, Namdev, editor^Aff2, Saraogi, Gaurav Kant, editor^Aff3

Practical Approaches for Metabolic Engineering

Mohanty, Sudipta Kumar^Aff3, Indu, B. K.^Aff3, Achar, Sharad S.^Aff3, Suhasa, G.^Aff3

Anuradha, M., editor^Aff1, Balasubramanya, S., editor^Aff2

CRISPR in Zebrafish

Challa, Anil Kumar^Aff11

Turksen, Kursad, Series Editor^Aff1, Carbonell, Pablo, Series Editor^Aff2, Roig, Joan, Series Editor^Aff3, Berenjian, Aydin, Series Editor^Aff4, Levite, Mia, Series Editor^Aff5, Bosserhoff, Anja K., Series Editor^Aff6, Wolyniak, Michael J., editor^Aff7, Pattison, Donna L., editor^Aff8, Pieczynski, Jay N., editor^Aff9, Santisteban, Maria S., editor^Aff10

Identifying Suitable Target Regions and Analyzing Off-Target Effects of Therapeutic Oligonucleotides

Pedersen, Lykke^Aff5, Hagedorn, Peter H.^Aff5, Koch, Troels^Aff5

Gissberg, Olof^Aff2, Zain, Rula^Aff3, Lundin, Karin E.^Aff4, Walker, John M.^Aff1

Exploring 5′-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency

Mobergslien, Anne^Aff3, Sioud, Mouldy^Aff3

Sioud, Mouldy^Aff2, Walker, John M.^Aff1

Metabolic Network Reconstructions to Predict Drug Targets and Off-Target Effects

Rawls, Kristopher^Aff3, Dougherty, Bonnie V.^Aff3, Papin, Jason^Aff3

Nagrath, Deepak^Aff2, Walker, John M.^Aff1

Versatile plant genome engineering using anti-CRISPR-Cas12a systems

He, Yao^{Aff1, Aff2}, Liu, Shishi^{Aff2, Aff3}, Chen, Long^{Aff4, Aff5}, Pu, Dongkai, Zhong, Zhaohui, Xu, Tang, Ren, Qiurong, Dong, Chuan, Wang, Yawei, Wang, Danning, Zheng, Xuelian, Guo, Fengbiao^{Aff6, Aff7, IDs1142702427047_cor1}, Zhang, Tao^{Aff4, Aff5, IDs1142702427047_cor2}, Qi, Yiping^{Aff8, Aff9, IDs1142702427047_cor3}, Zhang, Yong^{Aff1, Aff2, IDs1142702427047_cor4}

CRISPR/Cas9-mediated knockout strategies for enhancing immunotherapy in breast cancer

Xu, Chenchen^{Aff1, IDs00210024032082_cor1}

RNA Interference Screening for Genes Regulating Drosophila Muscle Morphogenesis

Kaya-Çopur, Aynur^Aff3, Schnorrer, Frank^Aff3

Rønning, Sissel Beate^Aff2, Walker, John M.^Aff1

CRISPR/Cas genome editing for cotton precision breeding: mechanisms, advances, and prospects

Vijay Sheri, Harikrishnan Mohan, Phanikanth Jogam, Anshu Alok, Gulab Khan Rohela, Baohong Zhang

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Physiopathological effects of entrance versus distal spread-out Bragg peak on mouse spinal cord neurons

Filippo Torrisi, Francesco Paolo Cammarata, Valentina Bravatà, Marco Calvaruso, Cristiana Alberghina, Anna Maria Pavone, Giada Petringa, Giuseppe Antonio Pablo Cirrone, Simona Denaro, Anna Gervasi, Simona D’Aprile, Nunzio Vicario, Emanuele Scifoni, Pietro Pisciotta, Giorgio Russo, Rosalba Parenti

electronic resource

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Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective

Srividhya Venkataraman, David Zaruk, Kathleen Hefferon

electronic resource

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Ex Vivo Dual Perfusion of the Human Placenta: Disease Simulation, Therapeutic Pharmacokinetics and Analysis of Off-Target Effects

Brownbill, Paul^{Aff4, Aff5}, Sebire, Neil^Aff6, McGillick, Erin V.^{Aff7, Aff8}, Ellery, Stacey^{Aff7, Aff8}, Murthi, Padma^{Aff7, Aff8, Aff9}

Murthi, Padma^Aff2, Vaillancourt, Cathy^Aff3, Walker, John M.^Aff1

RNAi-Mediated Knockdown of Protein Expression

Baumann, Volker^Aff5, Lorenzer, Cornelia^Aff5, Thell, Michael^Aff5, Winkler, Anna-Maria^Aff5, Winkler, Johannes^{Aff5, Aff6}

Kaufmann, Michael^Aff2, Klinger, Claudia^Aff3, Savelsbergh, Andreas^Aff4, Walker, John M.^Aff1

A Guide to Genome-Wide In Vivo RNAi Applications in Drosophila

Kaya-Çopur, Aynur^Aff3, Schnorrer, Frank^Aff3

Dahmann, Christian^Aff2, Walker, John M.^Aff1

AttSiOff: a self-attention-based approach on siRNA design with inhibition and off-target effect prediction

Liu, Bin, Yuan, Ye^{Aff1, IDs44258024000191_cor2}, Pan, Xiaoyong, Shen, Hong-Bin, Jin, Cheng^{Aff2, IDs44258024000191_cor5}

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Chehelgerdi, Mohammad^{Aff1, Aff2, IDs12943023019255_cor1}, Chehelgerdi, Matin^{Aff1, Aff2}, Khorramian-Ghahfarokhi, Milad, Shafieizadeh, Marjan, Mahmoudi, Esmaeil, Eskandari, Fatemeh, Rashidi, Mohsen^{Aff6, Aff7}, Arshi, Asghar, Mokhtari-Farsani, Abbas^{Aff1, Aff9}